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Tempest Therapeutics Inc.

7.49

+0.26003.60%

Post-market: 7.500.0100+0.13%19:25 EDT

Volume:29.18K

Turnover:212.14K

Market Cap:30.61M

PE:-0.38

High:7.49

Open:7.15

Low:7.05

Close:7.23

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Overview Company News Filings

Tempest Therapeutics Receives Green Light from China's NMPA for Pivotal Trial of Amezalpat Combination Therapy for First-Line HCC

Tempest Therapeutics Inc. Files Prospectus for $6.25 Million Direct Offering to Fund Strategic Initiatives and Operations

Tempest Therapeutics Announces $4.6 Million Registered Direct Offering of Common Stock to Institutional Investor

BRIEF-Tempest Therapeutics Terminates ATM Prospectus Supplement Dated February 6, 2025 - SEC Filing

Tempest Therapeutics Suspends Prospectus Supplement, Halts Securities Sales Under Jefferies Agreement

Top Premarket Gainers

MT Newswires Live

24H｜Chinese ADRs Gain Ahead of US-China Trade Talks; AppLovin, Robinhood Dip Missing S&P 500 Inclusion

Tiger Newspress

Stocks to Watch: Children's Place, Tempest Therapeutics

Tempest Therapeutics Inc. Announces Management Transition to Consulting Roles for CEO, CFO, and CMO

Tempest Therapeutics Secures Orphan Drug Designation from European Medicines Agency for Amezalpat in Hepatocellular Carcinoma Treatment

Tempest Therapeutics Inc reports results for the quarter ended March 31 - Earnings Summary

Tempest Therapeutics Inc expected to post a loss of $3.51 a share - Earnings Preview

Tempest Therapeutics Reports Q1 2025 Results: Net Loss Widens to $10.9M, EPS at $3.16

Tempest Therapeutics Inc expected to post a loss of $3.29 a share - Earnings Preview

Tempest Presents New Amezalpat MOA Data Reinforcing Its Potential as Novel Cancer Treatment at the 2025 AACR Annual Meeting

Tempest Therapeutics Cut to Sector Perform From Sector Outperform by Scotiabank

HC Wainwright Downgrades Tempest Therapeutics to Neutral From Buy

MT Newswires Live

BUZZ-Tempest rises as company eyes potential merger to advance liver cancer drug

Tempest Therapeutics Seeks Partner as It Explores Strategic Alternatives

Tempest Therapeutics to explore strategic alternatives

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Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Tempest Therapeutics Inc. published the original content used to generate this news brief via GlobeNewswire  on June 30, 2025, and is solely responsible for the information contained therein.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250630:nNDL867ZvB:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IE00B64PRP62.GBP","IE00BKPKM429.USD","TPST","BK4112","IE00B3QW5Z07.USD","NDAQ","LU2095319765.USD","BK4139","BK4588","IE00BGHQF748.EUR","BK4585","LU2210150020.SGD","LU2210149790.SGD"],"gpt_icon":0},{"id":"2543554240","title":"Tempest Therapeutics Inc. Files Prospectus for $6.25 Million Direct Offering to Fund Strategic Initiatives and Operations","url":"https://stock-news.laohu8.com/highlight/detail?id=2543554240","media":"Reuters","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2543554240?lang=en_us&edition=fundamental","pubTime":"2025-06-13 04:19","pubTimestamp":1749759577,"startTime":"0","endTime":"0","summary":"Tempest Therapeutics Inc. has announced its entry into a securities purchase agreement with a single institutional investor, as detailed in a recent prospectus filed with the Securities and Exchange Commission. The agreement allows Tempest to issue and sell 405,000 shares of common stock and prefunded warrants for 334,000 additional shares in a registered direct offering. The offering, priced at $6.25 per share of common stock and $6.249 per prefunded warrant, is aimed at raising funds to support strategic alternatives and general corporate purposes. The net proceeds, combined with existing cash reserves, are expected to fund the company's operations into the second quarter of 2026, although this estimate may change based on future financial needs. The company has engaged Cooley LLP to provide a legal opinion on the validity of the securities being issued.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250612:nNDLpsQ8N:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","TPST"],"gpt_icon":0},{"id":"2542815745","title":"Tempest Therapeutics Announces $4.6 Million Registered Direct Offering of Common Stock to Institutional Investor","url":"https://stock-news.laohu8.com/highlight/detail?id=2542815745","media":"Reuters","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2542815745?lang=en_us&edition=fundamental","pubTime":"2025-06-11 20:00","pubTimestamp":1749643248,"startTime":"0","endTime":"0","summary":"Tempest Therapeutics Inc., a clinical-stage biotechnology company focused on developing targeted and immune-mediated cancer therapeutics, has announced a $4.6 million registered direct offering of common stock. This transaction involves the sale of 739,000 shares at $6.25 each to a single institutional investor. H.C. Wainwright & Co. is serving as the exclusive placement agent for the offering. The company plans to use the net proceeds to support its strategic alternative process and for general corporate purposes. The offering is expected to close around June 12, 2025, pending customary closing conditions.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Tempest Therapeutics Inc. published the original content used to generate this news","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250611:nNDL3jHlQR:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IE00B64PRP62.GBP","LU2210149790.SGD","IE00BGHQF748.EUR","TPST","BK4112","IE00B3QW5Z07.USD","LU2095319765.USD","LU2210150020.SGD","BK4139","IE00BKPKM429.USD","BK4585","BK4588","NDAQ"],"gpt_icon":0},{"id":"2542589073","title":"BRIEF-Tempest Therapeutics Terminates ATM Prospectus Supplement Dated February 6, 2025 - SEC Filing","url":"https://stock-news.laohu8.com/highlight/detail?id=2542589073","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2542589073?lang=en_us&edition=fundamental","pubTime":"2025-06-11 19:52","pubTimestamp":1749642753,"startTime":"0","endTime":"0","summary":"BRIEF-Tempest Therapeutics Terminates ATM Prospectus Supplement Dated February 6, 2025 - SEC FilingJune 11  - Tempest Therapeutics Inc TPST.O:TEMPEST THERAPEUTICS INC - TERMINATES ATM PROSPECTUS SUPPLEMENT DATED FEBRUARY 6, 2025 - SEC FILINGSource text: [ID:n0001193125-25-138802]Further company coverage: TPST.O ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250611:nFWN3SE0EC:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","TPST"],"gpt_icon":0},{"id":"2542110589","title":"Tempest Therapeutics Suspends Prospectus Supplement, Halts Securities Sales Under Jefferies Agreement","url":"https://stock-news.laohu8.com/highlight/detail?id=2542110589","media":"Reuters","labels":["express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2542110589?lang=en_us&edition=fundamental","pubTime":"2025-06-11 19:41","pubTimestamp":1749642101,"startTime":"0","endTime":"0","summary":"Tempest Therapeutics Inc. has announced the suspension and termination of its prospectus supplement, originally filed on February 6, 2025, related to the company's common stock issuable under the Open Market Sale Agreement with Jefferies LLC. The decision, communicated on June 11, 2025, halts any sales of securities under this agreement until a new prospectus or registration statement is filed. Despite this change, the Sales Agreement itself remains effective. Further details about the Sales Agreement can be found in the company's previous Form 8-K filing with the Securities and Exchange Commission on June 20, 2024.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Tempest Therapeutics Inc. published the original content used to generate ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250611:nNDLBV8Cl:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["JEF","TPST"],"gpt_icon":0},{"id":"2542843643","title":"Top Premarket Gainers","url":"https://stock-news.laohu8.com/highlight/detail?id=2542843643","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2542843643?lang=en_us&edition=fundamental","pubTime":"2025-06-09 20:05","pubTimestamp":1749470754,"startTime":"0","endTime":"0","summary":"Tempest Therapeutics  shares were up 33% in recent premarket activity Monday, following a 3.9% increase in the previous session.VinFast Auto  stock rose 13% after the company reported higher Q1 revenue year over year.NewAmsterdam Pharma  shares were up nearly 12% after the company reported data from pre-specified Alzheimer's disease biomarker analyses in a phase 3 clinical trial.Graham  stock was up 10% pre-bell Monday after the company posted higher fiscal Q4 adjusted earnings and net sales from a year earlier.","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["NAMS","BK4161","GHM.AU","GHM","TPST","BK4139","BK7104","BK4099","VFS"],"gpt_icon":0},{"id":"1174710461","title":"24H｜Chinese ADRs Gain Ahead of US-China Trade Talks; AppLovin, Robinhood Dip Missing S&P 500 Inclusion","url":"https://stock-news.laohu8.com/highlight/detail?id=1174710461","media":"Tiger Newspress","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1174710461?lang=en_us&edition=fundamental","pubTime":"2025-06-09 10:00","pubTimestamp":1749434400,"startTime":"0","endTime":"0","summary":"$Tempest Therapeutics(TPST)$ said three of its c-suite executives transitioned to consulting agreements. The agreements have one-year terms and come as the cancer-treatment company is exploring strate","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":true,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BIDU","TPST","CVNA","PDD","PONY","BILI","JD","BABA","TME","XPEV","LI","WRD","IBKR","HOOD","NTES","APP","TCOM"],"gpt_icon":1},{"id":"2541896440","title":"Stocks to Watch: Children's Place, Tempest Therapeutics","url":"https://stock-news.laohu8.com/highlight/detail?id=2541896440","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2541896440?lang=en_us&edition=fundamental","pubTime":"2025-06-07 06:25","pubTimestamp":1749248700,"startTime":"0","endTime":"0","summary":"Children's Place posted a decline in same-store and overall sales in the first quarter. Management said uncertainty from tariffs and low consumer sentiment are putting pressure on finances. Shares sank 23% to $5.24 in postmarket trading Friday.Tempest Therapeutics said three of its c-suite executives transitioned to consulting agreements. The agreements have one-year terms and come as the cancer-treatment company is exploring strategic alternatives. Shares rose 7% to $8.80 after the market closed Friday.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4539","BK4094","BK4139","TPST","LENZ","BK4007","PLCE"],"gpt_icon":0},{"id":"2541898902","title":"Tempest Therapeutics Inc. Announces Management Transition to Consulting Roles for CEO, CFO, and CMO","url":"https://stock-news.laohu8.com/highlight/detail?id=2541898902","media":"Reuters","labels":["executive"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2541898902?lang=en_us&edition=fundamental","pubTime":"2025-06-07 04:06","pubTimestamp":1749240414,"startTime":"0","endTime":"0","summary":"Tempest Therapeutics Inc. has announced management changes as part of a plan to extend its capital resources and explore strategic alternatives. Effective June 5, 2025, CEO Stephen Brady, EVP and Chief Medical Officer Samuel Whiting, and CFO Nicholas Maestas have transitioned to consulting roles with the company. Each will continue to serve in their respective executive capacities under one-year consulting agreements. The transitions come without any disagreements between the executives and the company.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Tempest Therapeutics Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Secur","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250606:nNDL4N84dv:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"executive","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["TPST","BK4139"],"gpt_icon":0},{"id":"2541102772","title":"Tempest Therapeutics Secures Orphan Drug Designation from European Medicines Agency for Amezalpat in Hepatocellular Carcinoma Treatment","url":"https://stock-news.laohu8.com/highlight/detail?id=2541102772","media":"Reuters","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2541102772?lang=en_us&edition=fundamental","pubTime":"2025-06-05 20:00","pubTimestamp":1749124832,"startTime":"0","endTime":"0","summary":"Tempest Therapeutics Secures Orphan Drug Designation from European Medicines Agency for Amezalpat in Hepatocellular Carcinoma Treatment. Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Tempest Therapeutics Inc. published the original content used to generate this news brief via GlobeNewswire  on June 05, 2025, and is solely responsible for the information contained therein.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250605:nNDL9VgTS9:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IE00BKPKM429.USD","TPST","BK4588","LU2210149790.SGD","IE00B3QW5Z07.USD","NDAQ","BK4585","LU2210150020.SGD","LU2095319765.USD","IE00B64PRP62.GBP","BK4112","BK4139","IE00BGHQF748.EUR"],"gpt_icon":0},{"id":"2535391922","title":"Tempest Therapeutics Inc reports results for the quarter ended March 31 - Earnings Summary","url":"https://stock-news.laohu8.com/highlight/detail?id=2535391922","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2535391922?lang=en_us&edition=fundamental","pubTime":"2025-05-16 19:59","pubTimestamp":1747396789,"startTime":"0","endTime":"0","summary":"Tempest Therapeutics Inc reports results for the quarter ended March 31 - Earnings SummaryTempest Therapeutics Inc TPST.OQ reported a quarterly adjusted loss of $3.16 per share for the quarter ended M","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250516:nL8N3RO0VS:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["TPST"],"gpt_icon":0},{"id":"2535047824","title":"Tempest Therapeutics Inc  expected to post a loss of $3.51 a share - Earnings Preview","url":"https://stock-news.laohu8.com/highlight/detail?id=2535047824","media":"Reuters","labels":["dataReport","preview"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2535047824?lang=en_us&edition=fundamental","pubTime":"2025-05-14 19:04","pubTimestamp":1747220678,"startTime":"0","endTime":"0","summary":"Tempest Therapeutics Inc  expected to post a loss of $3.51 a share - Earnings Preview Tempest Therapeutics Inc TPST.OQ TPST.O is expected to show no change in quarterly revenue when it reports  result","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250514:nL8N3RM11P:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"Tempest Therapeutics Inc  expected to post a loss of $3.51 a share - Earnings Preview","news_tag":"dataReport,preview","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["TPST"],"gpt_icon":0},{"id":"2535082637","title":"Tempest Therapeutics Reports Q1 2025 Results: Net Loss Widens to $10.9M, EPS at $3.16","url":"https://stock-news.laohu8.com/highlight/detail?id=2535082637","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2535082637?lang=en_us&edition=fundamental","pubTime":"2025-05-14 04:23","pubTimestamp":1747167829,"startTime":"0","endTime":"0","summary":"Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Tempest Therapeutics Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on May 13, 2025, and is solely responsible for the information contained therein.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250513:nNDL4ShLRd:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["TPST"],"gpt_icon":0},{"id":"2533588436","title":"Tempest Therapeutics Inc  expected to post a loss of $3.29 a share - Earnings Preview","url":"https://stock-news.laohu8.com/highlight/detail?id=2533588436","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2533588436?lang=en_us&edition=fundamental","pubTime":"2025-05-05 19:15","pubTimestamp":1746443706,"startTime":"0","endTime":"0","summary":"Tempest Therapeutics Inc  expected to post a loss of $3.29 a share - Earnings Preview Tempest Therapeutics Inc TPST.OQ TPST.O is expected to show no change in quarterly revenue when it reports  result","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250505:nL8N3RD0LX:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["TPST"],"gpt_icon":0},{"id":"2531263620","title":"Tempest Presents New Amezalpat MOA Data Reinforcing Its Potential as Novel Cancer Treatment at the 2025 AACR Annual Meeting","url":"https://stock-news.laohu8.com/highlight/detail?id=2531263620","media":"GlobeNewswire","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2531263620?lang=en_us&edition=fundamental","pubTime":"2025-04-29 04:05","pubTimestamp":1745870700,"startTime":"0","endTime":"0","summary":"BRISBANE, Calif., April 28, 2025  -- Tempest Therapeutics, Inc. , a clinical-stage biotechnology company developing first-in-classi targeted and immune-mediated therapeutics to fight cancer, today announced that a presentation of new data supporting the immune component of amezalpat’s purported dual mechanism of action that reinforces its potential as a novel cancer treatment at the 2025 American Association for Cancer Research  Annual Meeting.“The data presented at the AACR Annual Meeting show that amezalpat reduced tumor promoting immunosuppression by M2 macrophages and T regulatory cells resulting in immune activation. These data support the immune-mediated anti-cancer activity of the proposed dual MOA of amezalpat,” said Sam Whiting, M.D., Ph.D., chief medical officer and head of R&D at Tempest, “and are consistent with clinical data showing promising results in patients with HCC, RCC and CCA including in combination with approved immunotherapy. The results reinforce amezalpat’s no","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/tempest-presents-amezalpat-moa-data-200500767.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4139","TPST"],"gpt_icon":0},{"id":"2526565220","title":"Tempest Therapeutics Cut to Sector Perform From Sector Outperform by Scotiabank","url":"https://stock-news.laohu8.com/highlight/detail?id=2526565220","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2526565220?lang=en_us&edition=fundamental","pubTime":"2025-04-10 20:23","pubTimestamp":1744287780,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/TPST/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  April 10, 2025 08:23 ET (12:23 GMT)","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LENZ","TPST"],"gpt_icon":0},{"id":"2526653735","title":"HC Wainwright Downgrades Tempest Therapeutics to Neutral From Buy","url":"https://stock-news.laohu8.com/highlight/detail?id=2526653735","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2526653735?lang=en_us&edition=fundamental","pubTime":"2025-04-10 20:14","pubTimestamp":1744287261,"startTime":"0","endTime":"0","summary":"HC Wainwright Downgrades Tempest Therapeutics to Neutral From Buy","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["LENZ","TPST"],"gpt_icon":0},{"id":"2526496193","title":"BUZZ-Tempest rises as company eyes potential merger to advance liver cancer drug","url":"https://stock-news.laohu8.com/highlight/detail?id=2526496193","media":"Reuters","labels":["corporation","merge"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2526496193?lang=en_us&edition=fundamental","pubTime":"2025-04-10 05:12","pubTimestamp":1744233159,"startTime":"0","endTime":"0","summary":"BUZZ-Tempest rises as company eyes potential merger to advance liver cancer drug** Shares of cancer drug developer Tempest Therapeutics TPST.O rise ~9% to $7.79 in extended trading** TPST says it is exploring strategic alternatives, such as mergers or partnerships, to advance its cancer treatment programs** Company's pipeline includes its lead liver cancer drug, amezalpat, and TPST-1495, a treatment for familial adenomatous polyposis, a rare genetic disorder** Amezalpat received both Orphan Drug and Fast Track designations from the US FDA** As of last close, stock down 34% YTD","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250409:nL3N3QN280:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"corporation,merge","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","TPST"],"gpt_icon":0},{"id":"2526346401","title":"Tempest Therapeutics Seeks Partner as It Explores Strategic Alternatives","url":"https://stock-news.laohu8.com/highlight/detail?id=2526346401","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2526346401?lang=en_us&edition=fundamental","pubTime":"2025-04-10 05:01","pubTimestamp":1744232460,"startTime":"0","endTime":"0","summary":"Tempest Therapeutics is exploring strategic alternatives for the business, including mergers, partnerships, acquisition, joint ventures and licensing agreements.Shares rose 9.2% to $7.81 in post-market trading. Through Wednesday's close, the stock has fallen 85% over the past 12 months.The clinical-stage biotechnology company on Wednesday said that it hired MTS Health Partners as financial adviser for its strategic evaluation process.\"Given the positive data and commercial potential with this [company] pipeline, as well as the clearance from the Food and Drug Administration on the lead program's pivotal study, we believe this is a rare opportunity for a partner,\" Chief Executive Stephen Brady 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