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Prothena Corp PLC

4.77

-0.0600-1.24%

Volume:678.59K

Turnover:3.23M

Market Cap:256.75M

PE:-2.33

High:4.88

Open:4.83

Low:4.66

Close:4.83

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Overview Company News Filings

Buy/Sell: Wall Street's Top 10 Stock Calls This Week

Prothena Cut to Underperform From Neutral by B of A Securities

Prothena Corporation Plc : Bofa Global Research Cuts to Underperform From Neutral; Cuts Price Objective to $4 From $22

THOMSON REUTERS

BofA Securities Downgrades Prothena to Underperform From Neutral, $4 Price Target

MT Newswires Live

Prothena downgraded to Underperform at BofA after birtamimab fails in clinic

Update: Prothena Shares Fall, Stock Downgraded by Multiple Research Firms After Birtamimab Development Discontinued

MT Newswires Live

Prothena Corporation Plc : H.c. Wainwright Cuts Target Price to $14 From $30

THOMSON REUTERS

Prothena Shares Fall After Trial Results Miss, Job Cuts

Exchange-Traded Funds, Equity Futures Higher Pre-Bell Tuesday as US Delays EU Tariff Implementation

MT Newswires Live

Prothena Corporation Plc : Oppenheimer Cuts to Perform From Outperform

THOMSON REUTERS

BUZZ-U.S. STOCKS ON THE MOVE-CoreWeave, U.S. Steel, Southwest Airlines

Prothena Is Maintained at Buy by HC Wainwright & Co.

Chardan Adjusts PT on Prothena to $18 From $40 After Drug Removal From Model, Keeps Buy Rating

MT Newswires Live

Prothena price target lowered to $18 from $40 at Chardan

Prothena downgraded to Hold from Buy at Jefferies

Oppenheimer downgrades Prothena (PRTA) to a Hold

BUZZ-Ireland's Prothena drops as Jefferies downgrades to 'hold' after drug fails trial

Prothena Corporation Plc : Jefferies Cuts to Hold From Buy; Cuts Target Price to $6 From $32

THOMSON REUTERS

Prothena Corporation plc Publishes Presentation on Advancements in Life-Saving Therapies for Protein Dysregulation Diseases

BRIEF-Prothena Announces Phase 3 Affirm-Al Clinical Trial For Birtamimab In Patients With Al Amyloidosis Did Not Meet Primary Endpoint

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Wainwright Cuts Target Price to $14 From $30","url":"https://stock-news.laohu8.com/highlight/detail?id=2538628964","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2538628964?lang=en_us&edition=fundamental","pubTime":"2025-05-27 21:53","pubTimestamp":1748354022,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250527:nFWN3RZ1C9:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["PRTA","BK4139"],"gpt_icon":0},{"id":"2538466024","title":"Prothena Shares Fall After Trial Results Miss, Job Cuts","url":"https://stock-news.laohu8.com/highlight/detail?id=2538466024","media":"Dow Jones","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2538466024?lang=en_us&edition=fundamental","pubTime":"2025-05-27 20:28","pubTimestamp":1748348880,"startTime":"0","endTime":"0","summary":"Prothena shares fell after the company reported unfavorable trial results and said it would shrink its workforce.The stock was down 27% to $4.81 in pre-market trading Tuesday.The Irish biotechnology company said Friday its Phase 3 trial of a blood-disorder treatment had not met its primary or secondary endpoints. As a result, it was ending the trial, it said.Oppenheimer analysts downgraded the Prothena stock to perform from outperform, and removed its price target. The analyst said they are still optimistic about the company's internal and partnered programs, but the trial was a main driver behind their thesis.\"We're moving to the sidelines for now,\" they said in a research note.Chief Executive Daniel Welch called the results disappointing. He said Prothena is now planning what it called a substantial job cut in an effort to reduce expenses. It is also evaluating business options that it thinks could be in the best interest for shareholders.The company expects to share more details abo","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["PRTA","BK4139"],"gpt_icon":0},{"id":"2538466109","title":"Exchange-Traded Funds, Equity Futures Higher Pre-Bell Tuesday as US Delays EU Tariff Implementation","url":"https://stock-news.laohu8.com/highlight/detail?id=2538466109","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2538466109?lang=en_us&edition=fundamental","pubTime":"2025-05-27 20:21","pubTimestamp":1748348506,"startTime":"0","endTime":"0","summary":"The broad market exchange-traded fund SPDR S&P 500 ETF Trust (SPY) was up 1.5% and the actively traded Invesco QQQ Trust (QQQ) was 1.6% higher in Tuesday's premarket activity as US President Donald Tr","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":"1c45938e64e61ba4d59c3ce1543549b9","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":[".IXIC","NXT.AU","XLK","XRT","IGV","IYK","SLV","IYW","EXI","VIS","IBB","XLP","FAZ","XLF","NXT","XLI","PRTA","USO","SPY","SPY.AU","IYJ","XPRO","RTH",".DJI","VT","VDC","VHT","BITO",".SPX","VHT.AU","FAS","EQR","V","IGM","XLY","XLE","IPK","PMR","UNG","XSD","XLV","RTH.AU","EEM","IYE","IVV"],"gpt_icon":1},{"id":"2538466495","title":"Prothena Corporation Plc : Oppenheimer Cuts to Perform From Outperform","url":"https://stock-news.laohu8.com/highlight/detail?id=2538466495","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2538466495?lang=en_us&edition=fundamental","pubTime":"2025-05-27 20:21","pubTimestamp":1748348485,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250527:nFWN3RZ16E:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["PRTA","BK4139"],"gpt_icon":0},{"id":"2538946581","title":"BUZZ-U.S. STOCKS ON THE MOVE-CoreWeave, U.S. Steel, Southwest Airlines","url":"https://stock-news.laohu8.com/highlight/detail?id=2538946581","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2538946581?lang=en_us&edition=fundamental","pubTime":"2025-05-27 19:44","pubTimestamp":1748346274,"startTime":"0","endTime":"0","summary":"BUZZ-U.S. STOCKS ON THE MOVE-CoreWeave, U.S. Steel, Southwest AirlinesEikon search string for individual stock moves: STXBZThe Day Ahead newsletter: https://refini.tv/3LI4BU7The Morning News Call news","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250527:nL6N3RZ0GH:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0642271901.SGD","LU0300736062.USD","IE00B19Z8X17.USD","LU0320765646.SGD","X","LU0472753341.HKD","CRWV","LU0942090050.USD","LU0823413660.USD","AU","LU0516423174.USD","LU0589944569.HKD","LU0820561818.USD","PRTA","BK4504","LU0823426308.USD","BK4213","LU0231483743.USD","CRM","LU0314106906.USD","LU1668664300.SGD","LU1989764748.USD","LU0612318385.USD","LU1582986433.USD","LU0345780281.USD","LU0109392836.USD","XOM","LU1064927863.SGD","LU0496367417.USD","BK4588","LU0943347566.SGD","CVX","LU0327786744.USD","NEM","LU0683595622.HKD","LU0047473722.SGD","LU2125154935.USD","INFA","BARC.UK","LU0353189680.USD","LU2133065610.SGD","COP","LU0203347892.USD","LU1803068979.SGD","LU0198837287.USD","LU1718418525.SGD","BK4566","LUV"],"gpt_icon":1},{"id":"2538246352","title":"Prothena Is Maintained at Buy by HC Wainwright & Co.","url":"https://stock-news.laohu8.com/highlight/detail?id=2538246352","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2538246352?lang=en_us&edition=fundamental","pubTime":"2025-05-27 19:14","pubTimestamp":1748344440,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/PRTA/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  May 27, 2025 07:14 ET (11:14 GMT)","market":"other","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["PRTA"],"gpt_icon":0},{"id":"2538468804","title":"Chardan Adjusts PT on Prothena to $18 From $40 After Drug Removal From Model, Keeps Buy Rating","url":"https://stock-news.laohu8.com/highlight/detail?id=2538468804","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2538468804?lang=en_us&edition=fundamental","pubTime":"2025-05-27 18:47","pubTimestamp":1748342852,"startTime":"0","endTime":"0","summary":"Prothena (PRTA) has an average rating of overweight and mean price target of $30, according to analysts polled by FactSet.(MT Newswires covers equity, commodity and economic research from major banks ","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate","earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["PT","PRTA"],"gpt_icon":0},{"id":"2538622454","title":"Prothena price target lowered to $18 from $40 at Chardan","url":"https://stock-news.laohu8.com/highlight/detail?id=2538622454","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2538622454?lang=en_us&edition=fundamental","pubTime":"2025-05-27 17:30","pubTimestamp":1748338251,"startTime":"0","endTime":"0","summary":"Chardan lowered the firm’s price target on Prothena (PRTA) to $18 from $40 and keeps a Buy rating on the shares. The firm removed birtamimab from t...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/prothena-price-target-lowered-to-18-from-40-at-chardan-thefly?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/prothena-price-target-lowered-to-18-from-40-at-chardan-thefly?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["PRTA","BK4139"],"gpt_icon":0},{"id":"2538459960","title":"Prothena downgraded to Hold from Buy at Jefferies","url":"https://stock-news.laohu8.com/highlight/detail?id=2538459960","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2538459960?lang=en_us&edition=fundamental","pubTime":"2025-05-27 17:00","pubTimestamp":1748336424,"startTime":"0","endTime":"0","summary":"Jefferies downgraded Prothena (PRTA) to Hold from Buy with a price target of $6, down from $32. The company’s Phase III study in light-chain amyloi...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/prothena-downgraded-to-hold-from-buy-at-jefferies-thefly?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/prothena-downgraded-to-hold-from-buy-at-jefferies-thefly?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","PRTA"],"gpt_icon":0},{"id":"2538278455","title":"Oppenheimer downgrades Prothena (PRTA) to a Hold","url":"https://stock-news.laohu8.com/highlight/detail?id=2538278455","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2538278455?lang=en_us&edition=fundamental","pubTime":"2025-05-27 16:45","pubTimestamp":1748335539,"startTime":"0","endTime":"0","summary":"Prothena (PRTA – Research Report) received a Hold rating and price target from Oppenheimer analyst Jay Olson yesterday. The company’s shares closed...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/oppenheimer-downgrades-prothena-prta-to-a-hold?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/oppenheimer-downgrades-prothena-prta-to-a-hold?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["OPY","PRTA"],"gpt_icon":0},{"id":"2538845365","title":"BUZZ-Ireland's Prothena drops as Jefferies downgrades to 'hold' after drug fails trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2538845365","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2538845365?lang=en_us&edition=fundamental","pubTime":"2025-05-27 16:33","pubTimestamp":1748334831,"startTime":"0","endTime":"0","summary":"BUZZ-Ireland's Prothena drops as Jefferies downgrades to 'hold' after drug fails trial** Shares of therapy developer Prothena Corporation PRTA.O are down nearly 2% at $4.77 in pre-market trading** Jefferies downgrades the stock's rating to \"hold\" from \"buy\"; slashes PT to $6 from $32, a 8.8% discount to the last close** PRTA becomes stock with lowest PT, per Jefferies, on Wall Street ** We see uncertainty around the pipeline given the failure of the AL amyloidosis  drug - brokerage** Adds it finds \"risk\" in the co's Alzheimer's drug PRX012 phase 1 trial data      ** Co says phase 3 clinical trial of Birtamimab in patients with AL amyloidosis did not meet primary endpoint     ** Avg rating of  10 analysts is \"buy\"; median PT $29.5— data compiled by LSEG     ** PRTA falls ~52.49% YTD, up to last close  ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250527:nL6N3RZ09X:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["PRTA"],"gpt_icon":0},{"id":"2538434342","title":"Prothena Corporation Plc : Jefferies Cuts to Hold From Buy; Cuts Target Price to $6 From $32","url":"https://stock-news.laohu8.com/highlight/detail?id=2538434342","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2538434342?lang=en_us&edition=fundamental","pubTime":"2025-05-27 14:36","pubTimestamp":1748327761,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250527:nFWN3RZ0JN:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","PRTA"],"gpt_icon":0},{"id":"2537631731","title":"Prothena Corporation plc Publishes Presentation on Advancements in Life-Saving Therapies for Protein Dysregulation Diseases","url":"https://stock-news.laohu8.com/highlight/detail?id=2537631731","media":"Reuters","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2537631731?lang=en_us&edition=fundamental","pubTime":"2025-05-24 08:21","pubTimestamp":1748046069,"startTime":"0","endTime":"0","summary":"Prothena Corporation plc has released a presentation detailing its ongoing efforts in developing life-saving therapies for diseases related to protein dysregulation, such as Alzheimer's disease, Parkinson's disease, and transthyretin amyloidosis. The presentation highlights the company's focus on therapeutics engineered to eliminate pathogenic proteins while preserving normal biology, utilizing a biology-directed engine for disease-driven antibody engineering. It outlines multiple clinical programs, including three partnered Phase 2 programs and one wholly-owned Phase 1 program. Prothena has established strong collaborations with partners like Bristol Myers Squibb, Novo Nordisk, and Roche. The presentation also emphasizes the global impact of neurodegenerative diseases and the economic burden they pose. You can access the full presentation through the link below.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. 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