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Prothena Corp PLC

5.89

-0.1800-2.97%

Volume:132.63K

Turnover:793.69K

Market Cap:317.04M

PE:-2.87

High:6.14

Open:6.14

Low:5.87

Close:6.07

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Overview Company News Filings

Cantor Fitzgerald Keeps Their Hold Rating on Prothena (PRTA)

Prothena up 3% after announcing corporate restructuring, cash burn update

Prothena sees 2025 net cash burn from operating/investing at $170M-$178M

Prothena Chief Regulatory Officer Karp, Chief People Officer Ford to depart

Prothena Corp Public Ltd Co - Announces 63% Workforce Reduction - SEC Filing

THOMSON REUTERS

Prothena Corporation Announces 63% Workforce Reduction Amidst Strategic Reorganization

BRIEF-Prothena announces corporate restructuring

Prothena Corporation Announces Phase 3 Advancement of Prasinezumab for Early-Stage Parkinson's Disease

Prothena Corporation Plc - May Receive up to $105 Mln in 2026

THOMSON REUTERS

Prothena Announces Corporate Restructuring

THOMSON REUTERS

Prothena Corporation Plc - Announces 63% Workforce Reduction

THOMSON REUTERS

Prothena: Expects Discontinuation of Birtamimab Development Will Result in Approximate Decrease of $96 Mln (Midpoint) in Annualized Net Cash Burn

THOMSON REUTERS

Oppenheimer Sticks to Their Hold Rating for Prothena (PRTA)

Prothena Corporation Announces Advancement of Prasinezumab into Phase III Trials for Early-Stage Parkinson's Disease

Buy/Sell: Wall Street's Top 10 Stock Calls This Week

Prothena Cut to Underperform From Neutral by B of A Securities

Prothena Corporation Plc : Bofa Global Research Cuts to Underperform From Neutral; Cuts Price Objective to $4 From $22

THOMSON REUTERS

BofA Securities Downgrades Prothena to Underperform From Neutral, $4 Price Target

MT Newswires Live

Prothena downgraded to Underperform at BofA after birtamimab fails in clinic

Update: Prothena Shares Fall, Stock Downgraded by Multiple Research Firms After Birtamimab Development Discontinued

MT Newswires Live

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This move is aimed at substantially reducing operating costs to focus on remaining wholly-owned programs, obligations to partnered programs, and anticipated business development activities. The workforce reduction is expected to be completed by the end of the fourth quarter of 2025. The decision follows the company's May 2025 announcement to discontinue the development of birtamimab. Affected employees, both in the U.S. and internationally, will receive severance payments and benefits as per the company's amended severance plan. Notably, the employment of Carol D. Karp, Chief Regulatory Officer, and David A. Ford, Chief People Officer, will end on August 1, 2025, which will also result in specific compensation arrangements. The company estimates recognizing around $16 to $20 million in severance-related expenses. 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Roche, in collaboration with Prothena, will progress prasinezumab into Phase 3 development for early-stage Parkinson's disease. Additionally, Prothena anticipates the release of initial data in August from its Phase 1 ASCENT clinical trials for the PRX012 program, targeting Alzheimer's disease. Looking ahead, Novo Nordisk plans to share data from its Phase 2 clinical trial evaluating coramitug for ATTR-CM in the latter half of 2025. Furthermore, Prothena expects to complete a Phase 1 clinical trial for PRX019 in collaboration with Bristol Myers Squibb by 2026, and Bristol Myers Squibb aims to conclude a Phase 2 TargetTau-1 clinical trial evaluating BMS-986446 in Alzheimer's disease by 2027.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250618:nNDL29nLHn:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4559","BK4588","IE00BJT1NW94.SGD","LU1032466523.USD","LU0321505439.SGD","IE0009355771.USD","LU0061475181.USD","LU0114720955.EUR","BK4534","LU0237698245.USD","LU1718418525.SGD","BK4585","LU1868837136.USD","LU1670711040.USD","LU1868836757.USD","BK4007","LU1571399168.USD","LU1670710588.SGD","LU2125154935.USD","LU0225771236.USD","LU0456855351.SGD","LU1868837300.USD","IE00BFTCPJ56.SGD","IE00BSNM7G36.USD","LU0267386448.USD","LU1261432733.SGD","LU1323610961.USD","LU1670711123.USD","LU1093756325.SGD","LU2242646821.SGD","LU0306806265.USD","PRTA","LU1291159041.SGD","LU2133065610.SGD","LU0868494617.USD","LU2360032135.SGD","BK4139","LU0882574055.USD","LU1868836914.USD","LU0096364046.USD","LU1670710661.SGD","BK4532","IE0002141913.USD","LU1430594728.SGD","LU2242652126.USD","LU1093756168.USD","LU0321505868.SGD","LU1989771016.USD","LU0306807586.USD","BMY"],"gpt_icon":0},{"id":"2544900406","title":"Prothena Corporation Plc - 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The company’s shares closed last Friday at $5.08...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/oppenheimer-sticks-to-their-hold-rating-for-prothena-prta-blurbs?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/oppenheimer-sticks-to-their-hold-rating-for-prothena-prta-blurbs?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["OPY","PRTA"],"gpt_icon":0},{"id":"2543464294","title":"Prothena Corporation Announces Advancement of Prasinezumab into Phase III Trials for Early-Stage Parkinson's Disease","url":"https://stock-news.laohu8.com/highlight/detail?id=2543464294","media":"Reuters","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2543464294?lang=en_us&edition=fundamental","pubTime":"2025-06-16 13:06","pubTimestamp":1750050377,"startTime":"0","endTime":"0","summary":"Prothena Corporation plc has announced that its partner Roche will advance the investigational drug prasinezumab into Phase III development for early-stage Parkinson's disease. This decision is based on data from the Phase IIb PADOVA study and ongoing open-label extensions from both the PADOVA and the Phase II PASADENA studies. Prasinezumab is an anti-alpha-synuclein antibody targeting a biological driver of Parkinson's disease progression. While the primary endpoint of time to confirmed motor progression did not achieve statistical significance, positive trends were noted, suggesting potential clinical benefits. The ongoing studies are evaluating the long-term safety and efficacy of prasinezumab in over 750 patients with early-stage Parkinson's disease. Further results from these studies will be presented as they become available.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely i","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250616:nNDL1CKrWj:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["PRTA","BK4139"],"gpt_icon":0},{"id":"1116659555","title":"Buy/Sell: Wall Street's Top 10 Stock Calls This Week","url":"https://stock-news.laohu8.com/highlight/detail?id=1116659555","media":"The Fly","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1116659555?lang=en_us&edition=fundamental","pubTime":"2025-06-01 09:00","pubTimestamp":1748739600,"startTime":"0","endTime":"0","summary":"Wall Street experts reveal the 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