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Prothena Corp PLC

6.93

+0.06000.87%

Post-market: 6.930.00000.00%18:31 EDT

Volume:724.89K

Turnover:5.06M

Market Cap:373.02M

PE:-3.38

High:7.10

Open:6.89

Low:6.80

Close:6.87

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Overview Company News Filings

Chardan Adjusts PT on Prothena to $18 From $40 After Drug Removal From Model, Keeps Buy Rating

MT Newswires Live

Prothena price target lowered to $18 from $40 at Chardan

Prothena downgraded to Hold from Buy at Jefferies

Oppenheimer downgrades Prothena (PRTA) to a Hold

BUZZ-Ireland's Prothena drops as Jefferies downgrades to 'hold' after drug fails trial

Prothena Corporation plc Publishes Presentation on Advancements in Life-Saving Therapies for Protein Dysregulation Diseases

BRIEF-Prothena Announces Phase 3 Affirm-Al Clinical Trial For Birtamimab In Patients With Al Amyloidosis Did Not Meet Primary Endpoint

Prothena to Stop Birtamimab Development After Trial for AL Amyloidosis Fails to Meet Primary Endpoint

MT Newswires Live

Prothena trading resumes

Prothena to Cut Jobs, End Drug Trial After Missed Endpoints

Prothena announces AFFIRM-AL trial did not meet primary endpoint

Prothena trading halted, news pending

Prothena Corporation plc Conducted Annual Shareholder Meeting

Prothena (PRTA) Receives a Buy from Piper Sandler

H.C. Wainwright Keeps Their Buy Rating on Prothena (PRTA)

RBC Trims Price Target on Prothena to $18 From $20, Keeps Sector Perform, Speculative Risk

MT Newswires Live

RBC Capital Remains a Hold on Prothena (PRTA)

Prothena Is Maintained at Buy by Chardan Capital

Prothena Corporation PLC reports results for the quarter ended March 31 - Earnings Summary

Prothena Corp Q1 EPS $(1.12) Misses $(0.97) Estimate, Sales $2.83M Miss $8.05M Estimate

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The firm removed birtamimab from t...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/prothena-price-target-lowered-to-18-from-40-at-chardan-thefly?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/prothena-price-target-lowered-to-18-from-40-at-chardan-thefly?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["PRTA","BK4139"],"gpt_icon":0},{"id":"2538459960","title":"Prothena downgraded to Hold from Buy at Jefferies","url":"https://stock-news.laohu8.com/highlight/detail?id=2538459960","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2538459960?lang=en_us&edition=fundamental","pubTime":"2025-05-27 17:00","pubTimestamp":1748336424,"startTime":"0","endTime":"0","summary":"Jefferies downgraded Prothena (PRTA) to Hold from Buy with a price target of $6, down from $32. The company’s Phase III study in light-chain amyloi...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/prothena-downgraded-to-hold-from-buy-at-jefferies-thefly?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/prothena-downgraded-to-hold-from-buy-at-jefferies-thefly?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["PRTA","BK4139"],"gpt_icon":0},{"id":"2538278455","title":"Oppenheimer downgrades Prothena (PRTA) to a Hold","url":"https://stock-news.laohu8.com/highlight/detail?id=2538278455","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2538278455?lang=en_us&edition=fundamental","pubTime":"2025-05-27 16:45","pubTimestamp":1748335539,"startTime":"0","endTime":"0","summary":"Prothena (PRTA – Research Report) received a Hold rating and price target from Oppenheimer analyst Jay Olson yesterday. The company’s shares closed...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/oppenheimer-downgrades-prothena-prta-to-a-hold?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/oppenheimer-downgrades-prothena-prta-to-a-hold?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["OPY","PRTA"],"gpt_icon":0},{"id":"2538845365","title":"BUZZ-Ireland's Prothena drops as Jefferies downgrades to 'hold' after drug fails trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2538845365","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2538845365?lang=en_us&edition=fundamental","pubTime":"2025-05-27 16:33","pubTimestamp":1748334831,"startTime":"0","endTime":"0","summary":"BUZZ-Ireland's Prothena drops as Jefferies downgrades to 'hold' after drug fails trial** Shares of therapy developer Prothena Corporation PRTA.O are down nearly 2% at $4.77 in pre-market trading** Jefferies downgrades the stock's rating to \"hold\" from \"buy\"; slashes PT to $6 from $32, a 8.8% discount to the last close** PRTA becomes stock with lowest PT, per Jefferies, on Wall Street ** We see uncertainty around the pipeline given the failure of the AL amyloidosis  drug - brokerage** Adds it finds \"risk\" in the co's Alzheimer's drug PRX012 phase 1 trial data      ** Co says phase 3 clinical trial of Birtamimab in patients with AL amyloidosis did not meet primary endpoint     ** Avg rating of  10 analysts is \"buy\"; median PT $29.5— data compiled by LSEG     ** PRTA falls ~52.49% YTD, up to last close  ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250527:nL6N3RZ09X:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["PRTA"],"gpt_icon":0},{"id":"2537631731","title":"Prothena Corporation plc Publishes Presentation on Advancements in Life-Saving Therapies for Protein Dysregulation Diseases","url":"https://stock-news.laohu8.com/highlight/detail?id=2537631731","media":"Reuters","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2537631731?lang=en_us&edition=fundamental","pubTime":"2025-05-24 08:21","pubTimestamp":1748046069,"startTime":"0","endTime":"0","summary":"Prothena Corporation plc has released a presentation detailing its ongoing efforts in developing life-saving therapies for diseases related to protein dysregulation, such as Alzheimer's disease, Parkinson's disease, and transthyretin amyloidosis. The presentation highlights the company's focus on therapeutics engineered to eliminate pathogenic proteins while preserving normal biology, utilizing a biology-directed engine for disease-driven antibody engineering. It outlines multiple clinical programs, including three partnered Phase 2 programs and one wholly-owned Phase 1 program. Prothena has established strong collaborations with partners like Bristol Myers Squibb, Novo Nordisk, and Roche. The presentation also emphasizes the global impact of neurodegenerative diseases and the economic burden they pose. You can access the full presentation through the link below.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250524:nNDLb901jq:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4585","LU1670710588.SGD","LU1718418525.SGD","BK4534","LU1032466523.USD","LU1670711123.USD","LU0096364046.USD","LU0061475181.USD","LU0114720955.EUR","LU0321505439.SGD","LU2360032135.SGD","LU2133065610.SGD","BK4588","LU0882574055.USD","LU1585245621.USD","BK4139","LU1670710661.SGD","LU2125154935.USD","LU0306807586.USD","BK4559","LU0868494617.USD","LU1291159041.SGD","LU0237698245.USD","LU1989771016.USD","LU0225771236.USD","LU2125154778.USD","LU1571399168.USD","IE0009355771.USD","LU1261432733.SGD","PRTA","LU0306806265.USD","IE0002141913.USD","IE00BJJMRZ35.SGD","LU1093756168.USD","LU1868836914.USD","IE00BFXG1179.USD","LU0456855351.SGD","BK4581","LU0985481810.HKD","LU2242646821.SGD","BMY","IE00B2B36J28.USD","BK4007","LU1868836757.USD","IE00BFTCPJ56.SGD","IE00BJT1NW94.SGD","LU0267386448.USD","LU0321505868.SGD","LU2242652126.USD","LU1868836591.USD"],"gpt_icon":0},{"id":"2537415206","title":"BRIEF-Prothena Announces Phase 3 Affirm-Al Clinical Trial For Birtamimab In Patients With Al Amyloidosis Did Not Meet Primary Endpoint","url":"https://stock-news.laohu8.com/highlight/detail?id=2537415206","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2537415206?lang=en_us&edition=fundamental","pubTime":"2025-05-24 04:54","pubTimestamp":1748033660,"startTime":"0","endTime":"0","summary":"BRIEF-Prothena Announces Phase 3 Affirm-Al Clinical Trial For Birtamimab In Patients With Al Amyloidosis Did Not Meet Primary EndpointProthena Corporation PLC PRTA.O:PROTHENA ANNOUNCES PHASE 3 AFFIRM-","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250523:nTUABWPNBK:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["PRTA","BK4139"],"gpt_icon":0},{"id":"2537492152","title":"Prothena to Stop Birtamimab Development After Trial for AL Amyloidosis Fails to Meet Primary Endpoint","url":"https://stock-news.laohu8.com/highlight/detail?id=2537492152","media":"MT Newswires Live","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2537492152?lang=en_us&edition=fundamental","pubTime":"2025-05-24 04:42","pubTimestamp":1748032934,"startTime":"0","endTime":"0","summary":"Prothena  said late Friday that it will discontinue the development of birtamimab after the phase 3 Affirm-Al trial of monoclonal antibody failed to meet the primary endpoint in treating patients with AL amyloidosis, or amyloid light chain amyloidosis.The company said it will also stop the open-label extension of the Affirm-Al clinical trial.Prothena said it expects to provide details of its plans to reduce ongoing operating expenses, which include job cuts, in June and the results of its review of business options once finalized.","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["AL","IE00B19Z6F94.USD","BK4572","IE0034390439.USD","BK4139","BK4104","PRTA"],"gpt_icon":0},{"id":"2537152295","title":"Prothena trading resumes","url":"https://stock-news.laohu8.com/highlight/detail?id=2537152295","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2537152295?lang=en_us&edition=fundamental","pubTime":"2025-05-24 04:35","pubTimestamp":1748032511,"startTime":"0","endTime":"0","summary":"16:35 EDT Prothena (PRTA) trading resumes Published first on TheFly – the ultimate source for real-time, market-moving breaking financial news. Try...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/prothena-trading-resumes-thefly?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/prothena-trading-resumes-thefly?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["PRTA","BK4139"],"gpt_icon":0},{"id":"2537152321","title":"Prothena to Cut Jobs, End Drug Trial After Missed Endpoints","url":"https://stock-news.laohu8.com/highlight/detail?id=2537152321","media":"Dow Jones","labels":["executive"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2537152321?lang=en_us&edition=fundamental","pubTime":"2025-05-24 04:25","pubTimestamp":1748031900,"startTime":"0","endTime":"0","summary":"Prothena said it would reduce its workforce after a recent trial failed to meet its primary and secondary endpoints.The Irish biotechnology company is planning a \"substantial\" job cut as it aims to decrease expenses, Chief Executive Daniel Welch said Friday. It is also evaluating business options, and will provide more details on the cuts in June, he said.Prothena reported unfavorable data from a Phase 3 trial of birtamimab to treat the blood disorder AL amyloidosis. The study didn't meet its primary endpoint of time to all-cause mortality, the company said. The study also failed to meet the secondary endpoints of a 6-minute walk test distance and short-form-36 version 2 physical component score, Prothena said.Due to the results, Prothena said it would end the trial.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":"Prothena to Cut Jobs, End Drug Trial After Missed Endpoints","news_tag":"executive","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","PRTA"],"gpt_icon":0},{"id":"2537615280","title":"Prothena announces AFFIRM-AL trial did not meet primary endpoint","url":"https://stock-news.laohu8.com/highlight/detail?id=2537615280","media":"TIPRANKS","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2537615280?lang=en_us&edition=fundamental","pubTime":"2025-05-24 04:15","pubTimestamp":1748031315,"startTime":"0","endTime":"0","summary":"Prothena (PRTA) announced the Phase 3 AFFIRM-AL clinical trial evaluating birtamimab in patients with AL amyloidosis did not meet its primary endpo...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/prothena-announces-affirm-al-trial-did-not-meet-primary-endpoint-thefly?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/prothena-announces-affirm-al-trial-did-not-meet-primary-endpoint-thefly?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["IE0034390439.USD","AL","BK4572","BK4139","PRTA","BK4104","IE00B19Z6F94.USD"],"gpt_icon":0},{"id":"2537152877","title":"Prothena trading halted, news pending","url":"https://stock-news.laohu8.com/highlight/detail?id=2537152877","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2537152877?lang=en_us&edition=fundamental","pubTime":"2025-05-24 04:05","pubTimestamp":1748030719,"startTime":"0","endTime":"0","summary":"16:01 EDT Prothena (PRTA) trading halted, news pending Published first on TheFly – the ultimate source for real-time, market-moving breaking financ...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/prothena-trading-halted-news-pending-thefly?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/prothena-trading-halted-news-pending-thefly?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","PRTA"],"gpt_icon":0},{"id":"2536734054","title":"Prothena Corporation plc Conducted Annual Shareholder Meeting","url":"https://stock-news.laohu8.com/highlight/detail?id=2536734054","media":"Reuters","labels":["executive"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2536734054?lang=en_us&edition=fundamental","pubTime":"2025-05-17 04:06","pubTimestamp":1747425963,"startTime":"0","endTime":"0","summary":"Prothena Corporation plc held its annual general meeting of shareholders on May 13, 2025. During the meeting, shareholders approved several proposals. The amendment to the Prothena Corporation plc 2018 Long Term Incentive Plan, which increased the number of ordinary shares authorized for issuance by 2,000,000, was approved. The appointment of KPMG LLP as the company's independent registered public accounting firm for the fiscal year ending December 31, 2025, was ratified, and the board of directors was authorized to approve the remuneration of the auditor. Additionally, the compensation of the company's named executive officers was approved in a non-binding advisory vote.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. 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