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ASCLETIS-B

8.610

-0.490-5.38%

Volume:4.79M

Turnover:41.78M

Market Cap:8.30B

PE:-26.18

High:9.300

Open:9.110

Low:8.560

Close:9.100

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Overview Company News Filings

Ascletis Announces First Participants Dosed in U.S. Phase I Clinical Study of Asc50, a Potential Best-in-Class Oral Small Molecule Il-17 Inhibitor for the Treatment of Psoriasis

THOMSON REUTERS

Ascletis Pharma Inc. Announces First Participants Dosed in U.S. Phase I Clinical Trial of Potential Best-in-Class Psoriasis Treatment ASC50

HK Movers | HK's Biotech Shares Soar. JOINN Soars 8%; Fudan-Zhangjiang up 6%; HeartCare up 2%

Tiger Newspress

HK Movers | Biotech Stocks Jump. Canbridge Soars 40%; Ascletis Jumps 17%; TYK Medicines Gains 7%; HBM Holdings, Abbisko Up More Than 6%

Tiger Newspress

China's Biotech Moment Ignites a 60% Stock Rally That Beats AI

HK Movers｜Pharma Shares Rallied. Sino Biopharm Up 13%; Immunothech And Zai Lab Up 5%; Dualitybio And Grand Pharmaup 4%

Tiger Newspress

Ascletis Announces Poster Presentations on the Study Results of Asc30 and Asc47 at the 85TH Scientific Sessions of American Diabetes Association (Ada)

THOMSON REUTERS

Ascletis Pharma Inc. Announces Poster Presentations on Study Results of GLP-1R Agonist ASC30 and Weight Loss Drug Candidate ASC47 at ADA Scientific Sessions

HK Movers｜Pharma Shares Rallied. CSPC Pharma Up 9%; 3SBio Up 4%; Yihai Up 3%; Genscript Bio And JXR Up 2%.

Tiger Newspress

HK Movers｜HK Pharma Shares Kept Rally. Zai Lab Up 7%; Hutchmed Up 6%; Immunotech Up 5%

Tiger Newspress

BUZZ-Sagimet soars as oral acne drug aces late-stage trial in China

Sagimet Biosciences Shares Jump 52% Premarket After Oral Acne Drug With Partner Ascletis Met the Main Goals in a Late-Stage Trial

THOMSON REUTERS

Sagimet Biosciences Announces Positive Phase 3 Results for Denifanstat in Treating Moderate-to-Severe Acne

HK Movers｜Pharma Shares Jumped. Innovent Bio Up 15%; Zai Lab Up 5%; Junshi Bio And CSPC Pharma Up 4%

Tiger Newspress

Ascletis Pharma Announces Successful Phase III Trial of Denifanstat, a Groundbreaking Oral FASN Inhibitor for Acne Treatment

Ascletis Announces Phase Iii Trial of Denifanstat (Asc40), a First-in-Class, Once-Daily Oral Fasn Inhibitor for Acne, Meets All Endpoints

THOMSON REUTERS

Ascletis Pharma Inc - Announces Phase Iii Trial of Denifanstat Meets All Endpoints

THOMSON REUTERS

HK Movers｜HK's Pharma Shares Jumped. Medlive Up 8%; Sihuan Pharm And Junshi Bio Up 7%; Pharmaron And Fosun Pharma Up 5%

Tiger Newspress

Ascletis Pharma Faces Legal Setback with Seven-Year Exclusion Order for ASC41 and ASC43F Drugs

HK Movers | Biopharmaceutical Stocks Jump With SinoMab BioScience up 18%

Tiger Newspress

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Announces First Participants Dosed in U.S. Phase I Clinical Trial of Potential Best-in-Class Psoriasis Treatment ASC50","url":"https://stock-news.laohu8.com/highlight/detail?id=2544919934","media":"Reuters","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2544919934?lang=en_us&edition=fundamental","pubTime":"2025-06-18 07:49","pubTimestamp":1750204152,"startTime":"0","endTime":"0","summary":"Ascletis Pharma Inc. Announces First Participants Dosed in U.S. Phase I Clinical Trial of Potential Best-in-Class Psoriasis Treatment ASC50. Ascletis Pharma Inc. has announced the dosing of the first participants in its U.S. Phase I clinical trial of ASC50, a potential best-in-class oral small molecule IL-17 inhibitor for the treatment of psoriasis. This trial is designed to assess the safety, tolerability, and preliminary efficacy of ASC50. Preclinical data, showing higher oral exposure, longer half-life, and strong efficacy, suggest ASC50 could be a leading once-daily oral treatment option for psoriasis. The trial is randomized, double-blind, and placebo-controlled, involving both healthy participants and patients with mild-to-moderate plaque psoriasis. The results of this study are expected to be presented in the future.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely informati","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250617:nNDLbmXbJG:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["01672","BK1161","BK1574","BK1515"],"gpt_icon":0},{"id":"1176260919","title":"HK Movers | HK's Biotech Shares Soar. JOINN Soars 8%; Fudan-Zhangjiang up 6%; HeartCare up 2%","url":"https://stock-news.laohu8.com/highlight/detail?id=1176260919","media":"Tiger Newspress","labels":["movement"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1176260919?lang=en_us&edition=fundamental","pubTime":"2025-06-17 10:13","pubTimestamp":1750126422,"startTime":"0","endTime":"0","summary":"Hong Kong’s biotech stocks rose on Tuesday.JOINN soared 8%; Fudan-Zhangjiang rose 6%; HeartCare rose 2%; CANbridge, Ascentage, WuXi XDC rose 1%.","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":"b1241f583e82227963a979cc1445c279","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":true,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"movement","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["06609","06127","02137","01349","03759","06606","09688","09966","09606","09995","01672","03347","01228","02269","06978","02359","02268"],"gpt_icon":0},{"id":"1194995839","title":"HK Movers | Biotech Stocks Jump. Canbridge Soars 40%; Ascletis Jumps 17%; TYK Medicines Gains 7%; HBM Holdings, Abbisko Up More Than 6%","url":"https://stock-news.laohu8.com/highlight/detail?id=1194995839","media":"Tiger Newspress","labels":["movement"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1194995839?lang=en_us&edition=fundamental","pubTime":"2025-06-16 11:22","pubTimestamp":1750044159,"startTime":"0","endTime":"0","summary":"Biotech stocks jumped on Monday. Canbridge soared 40%; Ascletis jumped 17%; TYK Medicines gained 7%; HBM Holdings, Abbisko up more than 6%.China’s biotechnology stocks have shaken off a four-year slum","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":"972a3d1b12236587576f532fe6844297","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":true,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"movement","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["09966","02359","02268","01672","06978","02269","09606","02137","03347","09688","09995","03759","06606"],"gpt_icon":0},{"id":"1112671838","title":"China's Biotech Moment Ignites a 60% Stock Rally That Beats AI","url":"https://stock-news.laohu8.com/highlight/detail?id=1112671838","media":"Bloomberg","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1112671838?lang=en_us&edition=fundamental","pubTime":"2025-06-15 17:06","pubTimestamp":1749978383,"startTime":"0","endTime":"0","summary":"China’s biotechnology stocks have shaken off a four-year slump to be among the hottest performers in Asia this year and funds are tipping further gains.The Hang Seng Biotech Index has surged more than","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":"837a503644945598b4960c4027e80bcb","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.bloomberg.com/news/articles/2025-06-15/china-s-biotech-moment-ignites-a-60-stock-rally-that-beats-ai","is_publish_highlight":true,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"lsy1584095487587","symbols":["09688","01672","06606","03347","03759","02269","09966","02137","09606","09995","06978","02268","02359"],"gpt_icon":1},{"id":"1153010109","title":"HK Movers｜Pharma Shares Rallied. Sino Biopharm Up 13%; Immunothech And Zai Lab Up 5%; Dualitybio And Grand Pharmaup 4%","url":"https://stock-news.laohu8.com/highlight/detail?id=1153010109","media":"Tiger Newspress","labels":["movement"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1153010109?lang=en_us&edition=fundamental","pubTime":"2025-06-12 09:38","pubTimestamp":1749692325,"startTime":"0","endTime":"0","summary":"Pharma Shares Rallied. Sino Biopharm up 13%; Immunothech and Zai Lab up 5%; Dualitybio and Grand Pharmaup 4%; Ascletis, Remegen and Beigene up 3%.","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":"a033ddb9c054b7a11d6c94b371cfc285","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":true,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"movement","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["06606","09688","02137","02268","09606","01672","03759","09966","02359","03347","06978","09995","02269"],"gpt_icon":0},{"id":"2542827313","title":"Ascletis Announces Poster Presentations on the Study Results of Asc30 and Asc47 at the 85TH Scientific Sessions of American Diabetes Association (Ada)","url":"https://stock-news.laohu8.com/highlight/detail?id=2542827313","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2542827313?lang=en_us&edition=fundamental","pubTime":"2025-06-09 08:15","pubTimestamp":1749428106,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250609:nTUAXHZMH:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK1161","BK1515","01672","BK1574"],"gpt_icon":0},{"id":"2542822731","title":"Ascletis Pharma Inc. Announces Poster Presentations on Study Results of GLP-1R Agonist ASC30 and Weight Loss Drug Candidate ASC47 at ADA Scientific Sessions","url":"https://stock-news.laohu8.com/highlight/detail?id=2542822731","media":"Reuters","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2542822731?lang=en_us&edition=fundamental","pubTime":"2025-06-09 08:04","pubTimestamp":1749427464,"startTime":"0","endTime":"0","summary":"Ascletis Pharma Inc. Announces Poster Presentations on Study Results of GLP-1R Agonist ASC30 and Weight Loss Drug Candidate ASC47 at ADA Scientific Sessions. Ascletis Pharma Inc. has announced that it will present the study results of two drug candidates, ASC30 and ASC47, at the 85th Scientific Sessions of the American Diabetes Association  in Chicago, U.S., scheduled from June 20 to 23, 2025. The presentations will include a poster on ASC30, an oral GLP-1R small molecule agonist, which is the subject of a first-in-human single ascending dose study in participants with obesity. Additionally, a separate poster will feature ASC47, a muscle-preserving weight loss drug candidate, which demonstrated superior weight loss in combination with Semaglutide compared to Semaglutide monotherapy in a preclinical model. Both presentations are set for June 22, 2025.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide ac","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250609:nNDL1wQQy9:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK1161","BK1574","BK1515","01672"],"gpt_icon":0},{"id":"1102844514","title":"HK Movers｜Pharma Shares Rallied. CSPC Pharma Up 9%; 3SBio Up 4%; Yihai Up 3%; Genscript Bio And JXR Up 2%.","url":"https://stock-news.laohu8.com/highlight/detail?id=1102844514","media":"Tiger Newspress","labels":["movement"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1102844514?lang=en_us&edition=fundamental","pubTime":"2025-06-06 14:14","pubTimestamp":1749190451,"startTime":"0","endTime":"0","summary":"HK pharma shares rallied. CSPC Pharma up 9%; 3SBio up 4%; Yihai up 3%; Genscript Bio and JXR up 2%.","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":"691e120ad0cf34ff3123a3b2b155f5fc","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":true,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"movement","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["03759","09688","06978","02359","02137","09966","01672","09995","06606","03347","09606","02268","02269"],"gpt_icon":0},{"id":"1147990132","title":"HK Movers｜HK Pharma Shares Kept Rally. Zai Lab Up 7%; Hutchmed Up 6%; Immunotech Up 5%","url":"https://stock-news.laohu8.com/highlight/detail?id=1147990132","media":"Tiger Newspress","labels":["movement"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1147990132?lang=en_us&edition=fundamental","pubTime":"2025-06-05 10:17","pubTimestamp":1749089820,"startTime":"0","endTime":"0","summary":"HK pharma shares kept rally. Zai Lab up 7%; Hutchmed up 6%; Immunotech up 5%; Sihuan Pharm, Akeso and Genscript Bio up 4%.","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":true,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"movement","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["02268","03759","09995","09966","02137","09688","09606","03347","06978","02359","02269","06606","01672"],"gpt_icon":0},{"id":"2540055112","title":"BUZZ-Sagimet soars as oral acne drug aces late-stage trial in China","url":"https://stock-news.laohu8.com/highlight/detail?id=2540055112","media":"Reuters","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2540055112?lang=en_us&edition=fundamental","pubTime":"2025-06-04 17:27","pubTimestamp":1749029233,"startTime":"0","endTime":"0","summary":"BUZZ-Sagimet soars as oral acne drug aces late-stage trial in China** Shares of drug developer Sagimet Biosciences SGMT.O rise 52% to $5.53 premarket** SGMT says its oral acne drug, denifanstat, met the main goals in a late-stage trial conducted by its Chinese partner Ascletis 1672.HK** Denifanstat showed 33.2% treatment success rate versus 14.6% for placebo** Denifanstat works by inhibiting the production of sebum, a key contributor to acne, through a novel mechanism of action, co says** The drug reduced total acne lesions by 57.4% compared to 35.4% with placebo** Ascletis plans to submit denifanstat for approval to Chinese regulators** As of last close, stock down 19.3% YTD  ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250604:nL3N3S70LM:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["01672","BK4139","BK1574","SGMT","BK1161","BK1515"],"gpt_icon":0},{"id":"2540055977","title":"Sagimet Biosciences Shares Jump 52% Premarket After Oral Acne Drug With Partner Ascletis Met the Main Goals in a Late-Stage Trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2540055977","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2540055977?lang=en_us&edition=fundamental","pubTime":"2025-06-04 17:15","pubTimestamp":1749028555,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250604:nFWN3S70BL:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["01672","BK1515","BK1161","BK1574","BK4139","SGMT"],"gpt_icon":0},{"id":"2540053848","title":"Sagimet Biosciences Announces Positive Phase 3 Results for Denifanstat in Treating Moderate-to-Severe Acne","url":"https://stock-news.laohu8.com/highlight/detail?id=2540053848","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2540053848?lang=en_us&edition=fundamental","pubTime":"2025-06-04 17:00","pubTimestamp":1749027616,"startTime":"0","endTime":"0","summary":"Sagimet Biosciences Inc., a clinical-stage biopharmaceutical company, announced the positive results of a Phase 3 clinical trial conducted by its license partner, Ascletis Bioscience Co. Ltd. in China, for the treatment of moderate to severe acne vulgaris. The trial evaluated the oral small molecule fatty acid synthase  inhibitor, denifanstat, which met all primary and secondary endpoints versus a placebo and was well tolerated by participants. This development marks an advancement in acne treatment, introducing a novel mechanism of action through FASN inhibition. Additionally, Sagimet has initiated a Phase 1 clinical trial in the United States for a second FASN inhibitor, TVB-3567, targeting acne treatment. The positive outcomes from the trial underscore the potential of FASN inhibition as a therapeutic approach for acne.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely informatio","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250604:nNDL9NgkYx:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4112","BK1515","01672","BK4139","IE00BGHQF748.EUR","IE00BKPKM429.USD","LU2210150020.SGD","BK1574","BK1161","IE00B3QW5Z07.USD","LU2210149790.SGD","LU2095319765.USD","BK4585","NDAQ","BK4588","SGMT","IE00B64PRP62.GBP"],"gpt_icon":0},{"id":"1129441589","title":"HK Movers｜Pharma Shares Jumped. Innovent Bio Up 15%; Zai Lab Up 5%; Junshi Bio And CSPC Pharma Up 4%","url":"https://stock-news.laohu8.com/highlight/detail?id=1129441589","media":"Tiger Newspress","labels":["movement"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1129441589?lang=en_us&edition=fundamental","pubTime":"2025-06-04 09:41","pubTimestamp":1749001285,"startTime":"0","endTime":"0","summary":"HK's Pharma Shares Jumped. 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The randomized, double-blind, placebo-controlled, multicenter trial conducted in China involved 480 patients. Denifanstat demonstrated a statistically significant improvement in treatment outcomes, with a 33.2% treatment success rate and reductions in total, inflammatory, and non-inflammatory lesion counts by 57.4%, 63.5%, and 51.9% respectively, compared to baseline. The trial results indicate that denifanstat was more effective than several FDA-approved acne treatments in placebo-adjusted percent treatment success. The drug maintained a favorable safety and tolerability profile throughout the study. 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In October 2024, the United States International Trade Commission issued an initial determination finding a violation of Section 337, recommending a seven-year exclusion order for these drugs. ASC41 is developed for treating non-alcoholic steatohepatitis  and targets thyroid hormone receptor beta , while ASC43F is a fixed-dose combination targeting both THRβ and farnesoid X receptor  for NASH treatment. Despite the ruling, Ascletis believes the outcome will not have a material adverse effect on its business and is seeking legal advice for an appeal. The company is committed to protecting its trade secrets and will provide updates on any significant developments.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. 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