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UpStream Bio Inc.

8.67

-1.1200-11.44%

Post-market: 8.670.00000.00%18:50 EDT

Volume:939.87K

Turnover:8.20M

Market Cap:471.82M

PE:-3.81

High:9.15

Open:8.72

Low:8.10

Close:9.79

52wk High:33.68

52wk Low:5.14

Shares:54.42M

Float Shares:31.42M

Volume Ratio:0.77

T/O Rate:2.99%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-2.2740

EPS(LYR):-5.5835

ROE:-35.43%

ROA:-23.99%

PB:1.39

PE(LYR):-1.55

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Overview Company News Filings

Upstream Bio Cut to In-Line From Outperform by Evercore ISI Group

Top Premarket Decliners

MT Newswires Live

Evercore ISI Downgrades Upstream Bio to In Line From Outperform, Adjusts PT to $15 From $40

MT Newswires Live

Upstream Bio Launches $150 Million At-The-Market Program

Upstream Bio announces $150 million at-the-market equity distribution agreement with Leerink Partners

Upstream Bio Inc - Enters Sales Agreement With Leerink Partners Llc for Common Stock Offering of up to $150 Mln - SEC Filing

THOMSON REUTERS

Upstream Bio Initiated at Buy: Verekitug’s Quarterly Dosing Strategy Positions It for Potential Best-in-Class Efficacy vs. TSLP Competitors

Verekitug’s Differentiated Long-Interval Dosing and Late-Stage Pipeline Position It as a Potential Respiratory Blockbuster

Buy Rating Backed by VALIANT Phase 2 Asthma Data and Differentiated, Infrequent-Dosing Profile for Verekitug

Upstream Bio Q4 net loss widens on higher R&D costs

Upstream Bio FY2025 net loss widens 128.4% to $143 million; research and development expenses rise 117.3% to $137 million

Upstream Bio Highlights Phase 3 Development Strategy for Verekitug and Reports Fourth Quarter and Full Year 2025 Financial Results

THOMSON REUTERS

Upstream Bio - to Initiate Dosing in Phase 3 Trials in Both Severe Asthma and Crswnp in Q1 2027

THOMSON REUTERS

Upstream Bio Inc Q4 Net Income USD -42.459 Million

THOMSON REUTERS

Upstream Bio Inc Q4 Collaboration Revenue USD 668 Thousand

THOMSON REUTERS

Upstream Bio Inc Q4 Operating Expenses USD 46.835 Million

THOMSON REUTERS

Upstream Bio Inc expected to post a loss of 70 cents a share - Earnings Preview

Upstream Bio CEO Makes Notable Move With Fresh Stock Sale

Buy Rating on UPB Driven by Robust Verekitug Phase 2 Data and Upcoming Phase 3 Catalysts in CRSwNP and Severe Asthma

Upstream Bio announces verekitug met the primary endpoint

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While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. 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Upstream Bio, Inc. has reported insider selling activity b...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/insider-trading/upstream-bio-ceo-makes-notable-move-with-fresh-stock-sale-insider-trading-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/insider-trading/upstream-bio-ceo-makes-notable-move-with-fresh-stock-sale-insider-trading-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["UPB","BK4139"],"gpt_icon":0},{"id":"2616340040","title":"Buy Rating on UPB Driven by Robust Verekitug Phase 2 Data and Upcoming Phase 3 Catalysts in CRSwNP and Severe Asthma","url":"https://stock-news.laohu8.com/highlight/detail?id=2616340040","media":"TIPRANKS","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2616340040?lang=en_us&edition=fundamental","pubTime":"2026-03-03 20:55","pubTimestamp":1772542554,"startTime":"0","endTime":"0","summary":"J.P. 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