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SPYRE THERAPEUTICS INC

43.21

+5.4014.28%

Post-market: 43.900.6900+1.60%19:40 EST

Volume:2.28M

Turnover:95.56M

Market Cap:3.35B

PE:-21.57

High:43.56

Open:37.82

Low:37.81

Close:37.81

52wk High:43.56

52wk Low:10.91

Shares:77.59M

Float Shares:63.83M

Volume Ratio:2.76

T/O Rate:3.57%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-2.0036

EPS(LYR):-3.1802

ROE:-38.08%

ROA:-30.20%

PB:11.20

PE(LYR):-13.59

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Overview Company News Filings

Spyre Therapeutics Rises on Narrower-Than-Expected 4Q Loss

Spyre Therapeutics rises 11.2%

Spyre Therapeutics (SYRE) Receives a Buy from Wedbush

BRIEF-Spyre Therapeutics Files For Mixed Shelf Of Up To $500 Million

Earnings Flash (SYRE) Spyre Therapeutics Posts Q4 Loss $-0.70, vs. FactSet Est of Loss of $-0.71

MT Newswires Live

Spyre Therapeutics files automatic mixed securities shelf

Spyre Therapeutics Inc: Files for Mixed Shelf of up to $500 Mln -SEC Filing

THOMSON REUTERS

Spyre posts Q4 net loss of USD 62.53 million

Spyre Therapeutics Reports Fourth Quarter and Full Year 2025 Financial Results and Provides Corporate Update

Spyre Therapeutics presents 20-week Phase 1 SPY003 data at ECCO 2026

Spyre Therapeutics vergibt neue Aktienoptionen an Mitarbeiter als Vergütungsanreiz

Spyre Therapeutics Announces Grants of Inducement Awards

Spyre Therapeutics CEO Cameron Turtle Reports Sale of Common Shares

Spyre Therapeutics Grants Stock Options to New Chief Commercial Officer

Spyre Therapeutics Appoints Kate Chevlen as Chief Commercial Officer

Spyre Therapeutics Announces Grants of Inducement Awards

Analysts Have Conflicting Sentiments on These Healthcare Companies: Eli Lilly & Co (LLY), Spyre Therapeutics (SYRE) and Astellas Pharma (OtherALPMF)

Wedbush Reaffirms Their Buy Rating on Spyre Therapeutics (SYRE)

Spyre Therapeutics highlights 2026 priorities, appoints Cheveln as CCO

BRIEF-Spyre Therapeutics Inc - Skyline Trial In UC Completes SPY001 Enrollment Ahead Of Schedule

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Therapeutics Rises on Narrower-Than-Expected 4Q Loss","url":"https://stock-news.laohu8.com/highlight/detail?id=2613929982","media":"Dow Jones","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2613929982?lang=en_us&edition=fundamental","pubTime":"2026-02-21 01:26","pubTimestamp":1771608360,"startTime":"0","endTime":"0","summary":"Shares of Spyre Therapeutics rose after the biotechnology company's fourth-quarter loss came in narrower than Wall Street expectations.Shares were trading up 9.9%, at $41.54, midday Friday. The stock is up 27% over the past year.The company on Thursday reported a loss of $62.5 million, or 70 cents a share, compared with a loss of $52.3 million, or 81 cents a share, a year earlier.Analysts surveyed by FactSet were expecting a loss of 71 cents a share.The Waltham, Mass., company, which is developing treatments for inflammatory-bowel disease and rheumatic diseases, didn't post any sales during the fourth quarter.It said it expects readouts from two Phase 2 trials this year.","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","BK4007","LENZ","BK4539","SYRE"],"gpt_icon":0},{"id":"2613296007","title":"Spyre Therapeutics rises 11.2%","url":"https://stock-news.laohu8.com/highlight/detail?id=2613296007","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2613296007?lang=en_us&edition=fundamental","pubTime":"2026-02-21 01:07","pubTimestamp":1771607240,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics (SYRE) is up 11.2%, or $4.25 to $42.06. Published first on TheFly – the ultimate source for real-time, market-moving breaking fi...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/spyre-therapeutics-rises-11-2-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/spyre-therapeutics-rises-11-2-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["SYRE","BK4539","BK4139","LENZ","BK4007"],"gpt_icon":0},{"id":"2612826723","title":"Spyre Therapeutics (SYRE) Receives a Buy from Wedbush","url":"https://stock-news.laohu8.com/highlight/detail?id=2612826723","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2612826723?lang=en_us&edition=fundamental","pubTime":"2026-02-20 21:56","pubTimestamp":1771595795,"startTime":"0","endTime":"0","summary":"Wedbush analyst maintained a Buy rating on Spyre Therapeutics today and set a price target of $65.00. In addition to Wedbush, Spyre Therapeutics al...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/spyre-therapeutics-syre-receives-a-buy-from-wedbush-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/spyre-therapeutics-syre-receives-a-buy-from-wedbush-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","SYRE"],"gpt_icon":0},{"id":"2612231957","title":"BRIEF-Spyre Therapeutics Files For Mixed Shelf Of Up To $500 Million","url":"https://stock-news.laohu8.com/highlight/detail?id=2612231957","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2612231957?lang=en_us&edition=fundamental","pubTime":"2026-02-20 07:09","pubTimestamp":1771542569,"startTime":"0","endTime":"0","summary":"BRIEF-Spyre Therapeutics Files For Mixed Shelf Of Up To $500 MillionFeb 19  - Spyre Therapeutics Inc SYRE.O:SPYRE THERAPEUTICS INC: FILES FOR MIXED SHELF OF UP TO $500 MILLION -SEC FILINGSource text: [ID:n0001628280-26-009814]Further company coverage: SYRE.O ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260219:nFWN3ZF1CG:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SYRE","BK4139"],"gpt_icon":0},{"id":"2612236373","title":"Earnings Flash (SYRE) Spyre Therapeutics Posts Q4 Loss $-0.70, vs. FactSet Est of Loss of $-0.71","url":"https://stock-news.laohu8.com/highlight/detail?id=2612236373","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2612236373?lang=en_us&edition=fundamental","pubTime":"2026-02-20 05:55","pubTimestamp":1771538141,"startTime":"0","endTime":"0","summary":"Earnings Flash (SYRE) Spyre Therapeutics Posts Q4 Loss $-0.70, vs. FactSet Est of Loss of $-0.71","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["SYRE"],"gpt_icon":0},{"id":"2612235405","title":"Spyre Therapeutics files automatic mixed securities shelf","url":"https://stock-news.laohu8.com/highlight/detail?id=2612235405","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2612235405?lang=en_us&edition=fundamental","pubTime":"2026-02-20 05:38","pubTimestamp":1771537137,"startTime":"0","endTime":"0","summary":"16:35 EST Spyre Therapeutics (SYRE) files automatic mixed securities shelf Published first on TheFly – the ultimate source for real-time, market-mo...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/spyre-therapeutics-files-automatic-mixed-securities-shelf-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/spyre-therapeutics-files-automatic-mixed-securities-shelf-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","LENZ","BK4539","BK4007","SYRE"],"gpt_icon":0},{"id":"2612235958","title":"Spyre Therapeutics Inc: Files for Mixed Shelf of up to $500 Mln -SEC Filing","url":"https://stock-news.laohu8.com/highlight/detail?id=2612235958","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2612235958?lang=en_us&edition=fundamental","pubTime":"2026-02-20 05:36","pubTimestamp":1771536996,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260219:nFWN3ZF1CG:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","SYRE"],"gpt_icon":0},{"id":"2612363238","title":"Spyre posts Q4 net loss of USD 62.53 million","url":"https://stock-news.laohu8.com/highlight/detail?id=2612363238","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2612363238?lang=en_us&edition=fundamental","pubTime":"2026-02-20 05:02","pubTimestamp":1771534974,"startTime":"0","endTime":"0","summary":"Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Spyre Therapeutics Inc. published the original content used to generate this news brief via GlobeNewswire  on February 19, 2026, and is solely responsible for the information contained therein.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260219:nNDL60v2cn:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4585","IE00BKPKM429.USD","IE00BGHQF748.EUR","BK4112","SG9999014039.USD","SG9999014013.SGD","BK4588","SYRE","LU2210150020.SGD","LU2095319765.USD","BK4139","SG9999014021.USD","IE00B64PRP62.GBP","NDAQ","LU2210149790.SGD","IE00B3QW5Z07.USD","LU0314104364.USD","SG9999014005.SGD"],"gpt_icon":0},{"id":"2612231560","title":"Spyre Therapeutics Reports Fourth Quarter and Full Year 2025 Financial Results and Provides Corporate Update","url":"https://stock-news.laohu8.com/highlight/detail?id=2612231560","media":"GlobeNewswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2612231560?lang=en_us&edition=fundamental","pubTime":"2026-02-20 05:02","pubTimestamp":1771534920,"startTime":"0","endTime":"0","summary":"On track for 6 proof-of-concept readouts in 2026 across the SKYLINE and SKYWAY Phase 2 trials Part A readouts from SKYLINE platform trial in ulcerative colitis (\"UC\") expected to begin in the second q","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2026/02/19/3241518/0/en/Spyre-Therapeutics-Reports-Fourth-Quarter-and-Full-Year-2025-Financial-Results-and-Provides-Corporate-Update.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SYRE","BK4009","CVR","BK4139","LENZ","LU2294711713.HKD","LU2357125470.USD","CCO","LU0823414551.USD","BK4539","LU2506951792.HKD","BK4161","BK4007","LU2249611893.SGD","LU0823414478.USD"],"gpt_icon":0},{"id":"2612456064","title":"Spyre Therapeutics presents 20-week Phase 1 SPY003 data at ECCO 2026","url":"https://stock-news.laohu8.com/highlight/detail?id=2612456064","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2612456064?lang=en_us&edition=fundamental","pubTime":"2026-02-18 21:00","pubTimestamp":1771419626,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics Inc. announced that it will present scientific posters at the 21st Congress of the European Crohn's and Colitis Organisation  on follow-up interim Phase 1 results for SPY003, a half-life extended anti-IL-23 monoclonal antibody being developed for inflammatory bowel disease. The company said the interim data include follow-up out to 20 weeks and will be presented in a poster suggesting potential for quarterly or twice-yearly maintenance dosing. Spyre also said it will present details of SKYLINE-UC, a platform trial in ulcerative colitis evaluating three long-acting antibodies as single agents and in combinations, along with preclinical mouse colitis data on combined anti-TL1A and anti-IL-23 therapy.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, ","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260218:nNDL6y0ksx:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4112","IE00B3QW5Z07.USD","LU2210149790.SGD","IE00B64PRP62.GBP","IE00BGHQF748.EUR","SG9999014013.SGD","LU0314104364.USD","BK4588","NDAQ","LU2095319765.USD","IE00BKPKM429.USD","SG9999014021.USD","SYRE","SG9999014005.SGD","BK4585","SG9999014039.USD","BK4139","LU2210150020.SGD"],"gpt_icon":0},{"id":"2609511800","title":"Spyre Therapeutics vergibt neue Aktienoptionen an Mitarbeiter als Vergütungsanreiz","url":"https://stock-news.laohu8.com/highlight/detail?id=2609511800","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2609511800?lang=en_us&edition=fundamental","pubTime":"2026-02-07 05:01","pubTimestamp":1770411701,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics Inc. hat bekannt gegeben, dass der Vergütungsausschuss des Unternehmens Aktienoptionen zum Erwerb von insgesamt 30.200 Stammaktien an fünf nicht-leitende Mitarbeitende als Eigenkapital-Zusatzvergütung gem dem 2018 Equity Inducement Plan gewhrt hat. Die Optionen haben eine Laufzeit von zehn Jahren, einen Ausübungspreis von 32,75 US-Dollar pro Aktie und unterliegen einem gestaffelten Vesting über vier Jahre, beginnend mit einem Viertel nach einem Jahr und anschlieender monatlicher Freigabe.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Spyre Therapeutics Inc. published the original content used to generate this news brief via GlobeNewswire  on February 06, 2026, and is solely responsible for the information contained ","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260206:nNDL7LfGvf:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SG9999014005.SGD","LU2210150020.SGD","SG9999014021.USD","LU0314104364.USD","IE00BKPKM429.USD","BK4588","LU2210149790.SGD","LU2095319765.USD","NDAQ","BK4139","SG9999014013.SGD","SG9999014039.USD","IE00B64PRP62.GBP","BK4112","SYRE","BK4585","IE00BGHQF748.EUR","IE00B3QW5Z07.USD"],"gpt_icon":0},{"id":"2609651156","title":"Spyre Therapeutics Announces Grants of Inducement Awards","url":"https://stock-news.laohu8.com/highlight/detail?id=2609651156","media":"GlobeNewswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2609651156?lang=en_us&edition=fundamental","pubTime":"2026-02-07 05:01","pubTimestamp":1770411660,"startTime":"0","endTime":"0","summary":"WALTHAM, Mass., Feb.  06, 2026  (GLOBE NEWSWIRE) -- Spyre Therapeutics, Inc. (NASDAQ: SYRE) (the “Company” or “Spyre”), a clinical-stage biotechnology company pioneering long-acting antibodies and ant","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2026/02/06/3234069/0/en/Spyre-Therapeutics-Announces-Grants-of-Inducement-Awards.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SYRE","BK4139","BK4007","BK4539","LENZ"],"gpt_icon":0},{"id":"2609468243","title":"Spyre Therapeutics CEO Cameron Turtle Reports Sale of Common Shares","url":"https://stock-news.laohu8.com/highlight/detail?id=2609468243","media":"Reuters","labels":["shareholding","insiderTrades","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2609468243?lang=en_us&edition=fundamental","pubTime":"2026-02-05 10:34","pubTimestamp":1770258845,"startTime":"0","endTime":"0","summary":"Cameron Turtle, Chief Executive Officer and Director of Spyre Therapeutics Inc., has reported a disposal of common shares of the company. The full filing can be accessed through the link below.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Spyre Therapeutics Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on February 04, 2026, and is solely responsible for the information contained therein.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260205:nNDL9jMrKy:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"Spyre Therapeutics CEO Cameron Turtle Reports Sale of Common Shares","news_tag":"shareholding,insiderTrades,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SYRE","BK4139"],"gpt_icon":0},{"id":"2606297632","title":"Spyre Therapeutics Grants Stock Options to New Chief Commercial Officer","url":"https://stock-news.laohu8.com/highlight/detail?id=2606297632","media":"Reuters","labels":["executive"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2606297632?lang=en_us&edition=fundamental","pubTime":"2026-01-26 15:50","pubTimestamp":1769413841,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics Inc. has granted stock options to purchase 108,155 shares of common stock to Kate Chevlen in connection with her appointment as Chief Commercial Officer. The options have a 10-year term and an exercise price of $34.09 per share, reflecting the closing price on January 22, 2026. Vesting terms specify that one-fourth of the options will vest on the first anniversary of Chevlen’s start date, with the remainder vesting monthly over the following three years, contingent on continued service with the company.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Spyre Therapeutics Inc. published the original content used to generate this news brief via GlobeNewswire  on January 23, 2026, and is solely responsible for the informat","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260126:nNDLcfj5mr:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"executive","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IE00B64PRP62.GBP","IE00BGHQF748.EUR","BK4139","IE00BKPKM429.USD","SG9999014005.SGD","LU0314104364.USD","IE00B3QW5Z07.USD","LU2095319765.USD","LU2210150020.SGD","NDAQ","SG9999014039.USD","BK4585","SG9999014021.USD","SYRE","LU2210149790.SGD","BK4112","SG9999014013.SGD","BK4588"],"gpt_icon":0},{"id":"2606292897","title":"Spyre Therapeutics Appoints Kate Chevlen as Chief Commercial Officer","url":"https://stock-news.laohu8.com/highlight/detail?id=2606292897","media":"Reuters","labels":["executive"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2606292897?lang=en_us&edition=fundamental","pubTime":"2026-01-26 15:23","pubTimestamp":1769412201,"startTime":"0","endTime":"0","summary":"Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Spyre Therapeutics Inc. published the original content used to generate this news brief on January 23, 2026, and is solely responsible for the information contained therein.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260126:nNDL4TN9sx:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"executive","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","SYRE"],"gpt_icon":0},{"id":"2605855312","title":"Spyre Therapeutics Announces Grants of Inducement Awards","url":"https://stock-news.laohu8.com/highlight/detail?id=2605855312","media":"GlobeNewswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2605855312?lang=en_us&edition=fundamental","pubTime":"2026-01-24 05:00","pubTimestamp":1769202000,"startTime":"0","endTime":"0","summary":"WALTHAM, Mass., Jan.  23, 2026  (GLOBE NEWSWIRE) -- Spyre Therapeutics, Inc. 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(OtherALPMF)","url":"https://stock-news.laohu8.com/highlight/detail?id=2604613704","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2604613704?lang=en_us&edition=fundamental","pubTime":"2026-01-20 01:30","pubTimestamp":1768843850,"startTime":"0","endTime":"0","summary":"Analysts have been eager to weigh in on the Healthcare sector with new ratings on Eli Lilly & Co (LLY – Research Report), Spyre Therapeutics (SYRE 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