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SPYRE THERAPEUTICS INC

13.57

+0.90007.10%

Post-market: 13.570.00000.00%17:50 EDT

Volume:740.39K

Turnover:9.94M

Market Cap:817.94M

PE:-4.27

High:13.81

Open:12.54

Low:12.53

Close:12.67

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Overview Company News Filings

BUZZ-Leerink Partners begins coverage on Spyre Therapeutics with 'outperform'

Spyre Therapeutics Initiated at Outperform by Leerink Partners

Leerink Partners Initiates Spyre Therapeutics With Outperform Rating, $45 Price Target

MT Newswires Live

Spyre Therapeutics Announces Grants of Inducement Awards

Spyre Therapeutics says first patient dosed in Phase 1 trial of SPY003

Spyre Therapeutics Announces First Participant Dosed in Phase 1 Trial of SPY003, its Novel Half-life Extended IL-23 Antibody

Wolfe Research Initiates Spyre Therapeutics at Outperform With $27 Price Target

MT Newswires Live

Spyre Therapeutics Announces Grants of Inducement Awards

JonesTrading Sticks to Its Hold Rating for Spyre Therapeutics (SYRE)

Spyre Therapeutics Faces Compliance Hurdles After Transition from Smaller Reporting Company Status

BRIEF-Spyre Therapeutics Files For Mixed Shelf Offering Of Up To $500 Million- SEC Filing

Spyre Therapeutics Inc reports results for the quarter ended December 31 - Earnings Summary

Spyre Therapeutics Q4 2024 GAAP EPS $(0.81) Beats $(1.01) Estimate

Spyre Therapeutics Inc Files for Mixed Shelf Offering of up to $500 Mln- SEC Filing

THOMSON REUTERS

Spyre Therapeutics Inc expected to post a loss of 99 cents a share - Earnings Preview

Spyre Therapeutics Announces Poster Presentation at the 20th Congress of the European Crohn's and Colitis Organisation

Spyre Therapeutics initiated with early-stage designation at Goldman Sachs

Spyre Therapeutics (SYRE) Gets a Buy from Stifel Nicolaus

Spyre Therapeutics Announces Grants of Inducement Awards

Wall Street Set to Open Sharply Higher Wednesday on Positive Inflation Data

MT Newswires Live

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their median PT is $55.75, accord","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250408:nL3N3QM153:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SYRE"],"gpt_icon":0},{"id":"2525889960","title":"Spyre Therapeutics Initiated at Outperform by Leerink Partners","url":"https://stock-news.laohu8.com/highlight/detail?id=2525889960","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2525889960?lang=en_us&edition=fundamental","pubTime":"2025-04-08 20:06","pubTimestamp":1744113960,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/SYRE/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  April 08, 2025 08:06 ET (12:06 GMT)","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LENZ","SYRE"],"gpt_icon":0},{"id":"2525985896","title":"Leerink Partners Initiates Spyre Therapeutics With Outperform Rating, $45 Price Target","url":"https://stock-news.laohu8.com/highlight/detail?id=2525985896","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2525985896?lang=en_us&edition=fundamental","pubTime":"2025-04-08 19:52","pubTimestamp":1744113178,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics (SYRE) has an average rating of Buy and mean price target of $54.67, according to analysts polled by FactSet.(MT Newswires covers equity, commodity and economic research from major ","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["LENZ","SYRE"],"gpt_icon":0},{"id":"2525730381","title":"Spyre Therapeutics Announces Grants of Inducement Awards","url":"https://stock-news.laohu8.com/highlight/detail?id=2525730381","media":"PR Newswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2525730381?lang=en_us&edition=fundamental","pubTime":"2025-04-05 04:05","pubTimestamp":1743797100,"startTime":"0","endTime":"0","summary":"WALTHAM, Mass., April 4, 2025 /PRNewswire/ -- Spyre Therapeutics, Inc.  , a clinical-stage biotechnology company utilizing best-in-class antibody engineering, dose optimization and rational therapeutic combinations to target improved efficacy and convenience in the treatment of IBD and other immune-mediated diseases, today announced that Spyre's independent Compensation Committee of the Board of Directors approved the grant of stock options to purchase 93,200 shares of common stock of Spyre to five non-executive employees as equity inducement awards under the Spyre Therapeutics, Inc. 2018 Equity Inducement Plan, as amended . The stock options were approved on April 1, 2025 and were material to each employee's acceptance of employment with Spyre, in accordance with Nasdaq Listing Rule 5635.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/spyre-therapeutics-announces-grants-inducement-200500867.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/spyre-therapeutics-announces-grants-inducement-200500867.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["SYRE","IBD","LENZ","BK4139"],"gpt_icon":0},{"id":"2522319815","title":"Spyre Therapeutics says first patient dosed in Phase 1 trial of SPY003","url":"https://stock-news.laohu8.com/highlight/detail?id=2522319815","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2522319815?lang=en_us&edition=fundamental","pubTime":"2025-03-28 04:10","pubTimestamp":1743106255,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics (SYRE) announced that it has initiated dosing in a healthy volunteer, Phase 1 clinical trial of its investigational half-life ex...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/spyre-therapeutics-says-first-patient-dosed-in-phase-1-trial-of-spy003?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/spyre-therapeutics-says-first-patient-dosed-in-phase-1-trial-of-spy003?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["LENZ","SYRE","BK4139"],"gpt_icon":0},{"id":"2522595385","title":"Spyre Therapeutics Announces First Participant Dosed in Phase 1 Trial of SPY003, its Novel Half-life Extended IL-23 Antibody","url":"https://stock-news.laohu8.com/highlight/detail?id=2522595385","media":"PR Newswire","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2522595385?lang=en_us&edition=fundamental","pubTime":"2025-03-28 04:05","pubTimestamp":1743105900,"startTime":"0","endTime":"0","summary":"Preclinical data demonstrates that SPY003 is highly potent and has potential forquarterly or biannual dosing, suggesting opportunity for improved efficacy andconvenience over first-generation anti-IL-23 monoclonal antibodies. Interim pharmacokinetic and safety data from healthy volunteers for SPY003 anticipatedin the second half of 2025. SPY003 is an investigational, novel, extended half-life monoclonal antibody targeting IL-23, being developed for the potential treatment of IBD. IBD is a chronic condition characterized by inflammation in the gastrointestinal tract and encompasses two main disorders: ulcerative colitis and Crohn's disease. In the United States, it is estimated that approximately 2.4 million individuals currently have IBD. In head-to-head preclinical studies, SPY003 demonstrated equivalent potency to risankizumab in inhibiting pSTAT signaling and IL-17 production and exhibited significantly longer half-life in non-human primates with the potential to deliver dosing in h","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/spyre-therapeutics-announces-first-participant-200500981.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/spyre-therapeutics-announces-first-participant-200500981.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LENZ","PK","IBD","BK4181","BK4218","SYRE","BK4139"],"gpt_icon":0},{"id":"2520626310","title":"Wolfe Research Initiates Spyre Therapeutics at Outperform With $27 Price Target","url":"https://stock-news.laohu8.com/highlight/detail?id=2520626310","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2520626310?lang=en_us&edition=fundamental","pubTime":"2025-03-18 19:16","pubTimestamp":1742296588,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics (SYRE) has an average rating of buy and mean price target of $55.11, according to analysts polled by FactSet.(MT Newswires covers equity, commodity and economic research from major ","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["LENZ","SYRE"],"gpt_icon":0},{"id":"2517466136","title":"Spyre Therapeutics Announces Grants of Inducement Awards","url":"https://stock-news.laohu8.com/highlight/detail?id=2517466136","media":"PR Newswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2517466136?lang=en_us&edition=fundamental","pubTime":"2025-03-08 05:40","pubTimestamp":1741383600,"startTime":"0","endTime":"0","summary":"WALTHAM, Mass., March 7, 2025 /PRNewswire/ -- Spyre Therapeutics, Inc.  , a clinical-stage biotechnology company utilizing best-in-class antibody engineering, dose optimization and rational therapeutic combinations to target improved efficacy and convenience in the treatment of IBD and other immune-mediated diseases, today announced that Spyre's independent Compensation Committee of the Board of Directors approved the grant of stock options to purchase 132,200 shares of common stock of Spyre to five non-executive employees as equity inducement awards under the Spyre Therapeutics, Inc. 2018 Equity Inducement Plan, as amended . The stock options were approved on March 3, 2025 and were material to each employee's acceptance of employment with Spyre, in accordance with Nasdaq Listing Rule 5635.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/spyre-therapeutics-announces-grants-inducement-214000337.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/spyre-therapeutics-announces-grants-inducement-214000337.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["SYRE","BK4139","LENZ","IBD"],"gpt_icon":0},{"id":"2516800166","title":"JonesTrading Sticks to Its Hold Rating for Spyre Therapeutics (SYRE)","url":"https://stock-news.laohu8.com/highlight/detail?id=2516800166","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2516800166?lang=en_us&edition=fundamental","pubTime":"2025-03-03 20:29","pubTimestamp":1741004970,"startTime":"0","endTime":"0","summary":"JonesTrading analyst Debanjana Chatterjee reiterated a Hold rating on Spyre Therapeutics (SYRE – Research Report) today. The company’s shares close...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/jonestrading-sticks-to-its-hold-rating-for-spyre-therapeutics-syre?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/jonestrading-sticks-to-its-hold-rating-for-spyre-therapeutics-syre?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["SYRE"],"gpt_icon":0},{"id":"2516535729","title":"Spyre Therapeutics Faces Compliance Hurdles After Transition from Smaller Reporting Company Status","url":"https://stock-news.laohu8.com/highlight/detail?id=2516535729","media":"TIPRANKS","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2516535729?lang=en_us&edition=fundamental","pubTime":"2025-03-01 14:01","pubTimestamp":1740808897,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics, Inc (SYRE) has disclosed a new risk, in the Share Price & Shareholder Rights category. 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Spyre Therapeutics Inc SYRE.O:SPYRE THERAPEUTICS INC FILES FOR MIXED SHELF OFFERING OF UP TO $500 MILLION- SEC FILINGSource text: [ID:n0001628280-25-008686]Further company coverage: SYRE.O ","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250227:nFWN3PI15K:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SYRE","BK4139"],"gpt_icon":0},{"id":"2514353725","title":"Spyre Therapeutics Inc reports results for the quarter ended December 31 - Earnings Summary","url":"https://stock-news.laohu8.com/highlight/detail?id=2514353725","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2514353725?lang=en_us&edition=fundamental","pubTime":"2025-02-28 05:43","pubTimestamp":1740692590,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics Inc reports results for the quarter ended December 31 - 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