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Spero Therapeutics Inc.

2.50

-0.0600-2.34%

Post-market: 2.520.0200+0.80%19:48 EDT

Volume:2.55M

Turnover:6.55M

Market Cap:139.78M

PE:-1.95

High:2.74

Open:2.54

Low:2.45

Close:2.56

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Overview Company News Filings

SPRO Stock Soars 245% on GSK-Partnered UTI Drug Meeting Study Goal

Top Midday Gainers

MT Newswires Live

Crude Oil Gains 2%; Macy's Lowers Earnings Forecast

Spero Therapeutics' Shares More Than Triple to $2.11 After Co to Stop Urinary Tract Infection Drug Trial Due to Early Success

THOMSON REUTERS

Spero Therapeutics Stock (SPRO) Rockets 225% on Clinical Trial Data

GSK reports PIVOT-PO study for tebipenem HBr stopped early for efficacy

Spero Therapeutics' Shares Nearly Triple to $2 Premarket After Co to Stop Urinary Tract Infection Drug Trial Due to Early Success

THOMSON REUTERS

Spero Therapeutics Announces Early Success in Phase 3 Trial of Tebipenem HBr for Complicated UTIs, Plans FDA Filing in 2025

GSK, Spero to stop urinary tract infection drug trial due to early success

TD Cowen Reaffirms Their Hold Rating on Spero Therapeutics (SPRO)

Spero Therapeutics Inc reports results for the quarter ended March 31 - Earnings Summary

BRIEF-Spero Therapeutics Q1 EPS USD -0.25

Spero Therapeutics Announces First Quarter 2025 Operating Results and Provides a Business Update

THOMSON REUTERS

Spero Therapeutics Q1 EPS USD -0.25

THOMSON REUTERS

Spero Therapeutics Inc - Expects Cash, Earned Milestones to Cover Expenses Into Q2 2026

THOMSON REUTERS

Spero Therapeutics Inc expected to post a loss of 55 cents a share - Earnings Preview

Spero Therapeutics to Report First Quarter 2025 Financial Results and Provide Business Update on Tuesday, May 13, 2025

THOMSON REUTERS

BRIEF-Spero Therapeutics Appoints Esther Rajavelu As President And Chief Executive Officer

Spero Therapeutics Appoints Esther Rajavelu as President and Chief Executive Officer

THOMSON REUTERS

Press Release: Spero Therapeutics Appoints Esther Rajavelu as President and Chief Executive Officer

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The drug, called tebipenem HBr, is being developed in partnership with GSK plc GSK.This late-stage study, called PIVOT-PO, enrolled hospitalized adult patients with cUTIs, including pyelonephritis . The decision to stop the study early was made following a recommendation from an independent committee, which found that the study met its primary endpoint of non-inferiority. In other words, treatment with tebipenem was as effective as intravenously  administered antibiotic imipenem-cilastatin, a commonly prescribed treatment for cUTIs. These findings are based on an interim analysis of data from 1,690 patients enrolled in the study.Based on the positive results, Spero’s partner, GSK, plans to submit a regulatory filing seeking approval for the drug with the FDA later","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/spro-stock-soars-245-gsk-151800230.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4139","BK4204","BK4532","GSK","LU1829250122.USD","SPRO","ADPT","UTI","BK4121","AGEN","BK4588","BK4585","BK4007","GSK.UK"],"gpt_icon":0},{"id":"2539403168","title":"Top Midday Gainers","url":"https://stock-news.laohu8.com/highlight/detail?id=2539403168","media":"MT 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efficacy","url":"https://stock-news.laohu8.com/highlight/detail?id=2538478669","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2538478669?lang=en_us&edition=fundamental","pubTime":"2025-05-28 19:20","pubTimestamp":1748431229,"startTime":"0","endTime":"0","summary":"GSK plc (GSK) and Spero Therapeutics (SPRO) announced that the pivotal Phase 3 PIVOT-PO trial evaluating tebipenem HBr, an investigational oral tre...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/gsk-reports-pivot-po-study-for-tebipenem-hbr-stopped-early-for-efficacy-thefly?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/gsk-reports-pivot-po-study-for-tebipenem-hbr-stopped-early-for-efficacy-thefly?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["LU1829250122.USD","GSK","BK4532","BK4588","BK4585","BK4139","GSK.UK","SPRO","BK4007"],"gpt_icon":0},{"id":"2538580478","title":"Spero Therapeutics' Shares Nearly Triple to $2 Premarket 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Trial of Tebipenem HBr for Complicated UTIs, Plans FDA Filing in 2025","url":"https://stock-news.laohu8.com/highlight/detail?id=2538420018","media":"Reuters","labels":["productRelease","dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2538420018?lang=en_us&edition=fundamental","pubTime":"2025-05-28 19:13","pubTimestamp":1748430803,"startTime":"0","endTime":"0","summary":"CAMBRIDGE, Mass., May 28, 2025 - Spero Therapeutics Inc. and GSK plc have announced the early conclusion of their pivotal Phase 3 PIVOT-PO trial for tebipenem HBr, an investigational oral treatment for complicated urinary tract infections , including pyelonephritis. The trial ended early following a recommendation from an Independent Data Monitoring Committee, which found that the primary endpoint of non-inferiority compared to intravenous imipenem-cilastatin had been met. The trial involved 1,690 patients and did not reveal any new safety concerns. If approved, tebipenem HBr could become the first oral carbapenem antibiotic available for U.S. patients with cUTIs. Data from the trial will be included in a planned FDA filing in the second half of 2025.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250528:nNDLfL7s:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease,dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0058720904.USD","LU0225284248.USD","LU1400636491.USD","BK5011","LU1400636657.SGD","IE00BWDBJ516.SGD","LU0971552830.HKD","LU0306807586.USD","LU1645745479.HKD","SPRO","LU1487256676.USD","BK4139","LU1228905540.USD","LU0203347892.USD","LU0575583348.USD","GSK.UK","LU1015430645.USD","LU1046248800.SGD","LU1400636574.HKD","LU1481600234.SGD","LU1228905037.USD","LU1302929846.USD","LU1064927863.SGD","LU0306806265.USD","LU0109981661.USD","LU0211331839.USD","IE00BQJZX424.USD","LU0971552673.USD","LU1481599808.USD","LU1670756490.USD","LU0985481810.HKD","LU1202635105.USD","LU1098665638.USD","LU0321505868.SGD","LU1035777561.USD","LU0321505439.SGD","LU0545562505.USD","LU0225771236.USD","LU0203345920.USD","LU0289739699.SGD","IE0034235071.USD"],"gpt_icon":0},{"id":"2538142005","title":"GSK, Spero to stop urinary tract infection drug trial due to early success","url":"https://stock-news.laohu8.com/highlight/detail?id=2538142005","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2538142005?lang=en_us&edition=fundamental","pubTime":"2025-05-28 19:10","pubTimestamp":1748430614,"startTime":"0","endTime":"0","summary":"GSK, Spero to stop urinary tract infection drug trial due to early successMay 28  - Spero Therapeutics SPRO.O and partner GSK GSK.L said on Wednesday that an experimental drug for complicated urinary tract infections met the main goal of a late-stage trial and the companies will be stopping the trial early for efficacy.  ","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250528:nL3N3S00TG:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0203345920.USD","LU1487256676.USD","LU0109981661.USD","LU0321505439.SGD","LU0985481810.HKD","LU1015430645.USD","LU1202635105.USD","LU0289739699.SGD","LU1645745479.HKD","LU1064927863.SGD","LU0225284248.USD","LU0971552673.USD","LU1400636657.SGD","LU1400636491.USD","SPRO","IE0034235071.USD","GSK.UK","LU0306807586.USD","LU1481600234.SGD","BK4139","LU1228905037.USD","LU1035777561.USD","LU0321505868.SGD","LU0545562505.USD","LU1670756490.USD","LU1302929846.USD","LU0203347892.USD","LU0575583348.USD","LU0306806265.USD","LU1481599808.USD","LU1098665638.USD","LU1400636574.HKD","IE00BQJZX424.USD","LU0211331839.USD","LU1228905540.USD","LU1046248800.SGD","LU0225771236.USD","LU0058720904.USD","BK5011","IE00BWDBJ516.SGD","LU0971552830.HKD"],"gpt_icon":0},{"id":"2536526732","title":"TD Cowen Reaffirms Their Hold Rating on Spero Therapeutics (SPRO)","url":"https://stock-news.laohu8.com/highlight/detail?id=2536526732","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2536526732?lang=en_us&edition=fundamental","pubTime":"2025-05-19 11:15","pubTimestamp":1747624513,"startTime":"0","endTime":"0","summary":"TD Cowen analyst Ritu Baral maintained a Hold rating on Spero Therapeutics (SPRO – Research Report) yesterday. 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