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Prelude Therapeutics Inc

6.52

+0.05000.77%

Volume:227.46K

Turnover:1.49M

Market Cap:519.27M

PE:-9.08

High:6.70

Open:6.57

Low:6.31

Close:6.47

52wk High:6.83

52wk Low:0.9807

Shares:79.64M

Float Shares:4.56M

Volume Ratio:0.41

T/O Rate:4.99%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-0.7183

EPS(LYR):-1.2929

ROE:-57.73%

ROA:-27.15%

PB:3.88

PE(LYR):-5.04

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Overview Company News Filings

Prelude Therapeutics Chief Business Officer Sean P. Brusky files initial beneficial ownership statement

Prelude Therapeutics management to meet with Citizens

Prelude Therapeutics to present PRT13722 preclinical poster at AACR Annual Meeting 2026

Prelude Therapeutics Announces Acceptance of Preclinical Abstract for PRT13722, a First-in-Class Oral KAT6A Selective Degrader at the 2026 AACR Annual Meeting

Prelude Therapeutics Is Maintained at Market Outperform by Citizens

Prelude Therapeutics price target raised to $6 from $3 at Citizens

Prelude Therapeutics Reports 2025 Results, Highlights JAK2 Program

Prelude Therapeutics Q4 EPS $(0.20) Misses $(0.03) Estimate, Sales $5.640M Miss $35.000M Estimate

Benzinga Earnings

Prelude Therapeutics reports $99.5 mln net loss for 2025

BRIEF-Prelude Therapeutics FY EPS USD -1.29

Press Release: Prelude Therapeutics Reports Full Year 2025 Financial Results and Provides Program Outlook for 2026

Prelude Therapeutics Inc expected to post a loss of 3 cents a share - Earnings Preview

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Brusky files initial beneficial ownership statement","url":"https://stock-news.laohu8.com/highlight/detail?id=2620827719","media":"Reuters","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2620827719?lang=en_us&edition=fundamental","pubTime":"2026-03-20 07:40","pubTimestamp":1773963603,"startTime":"0","endTime":"0","summary":"Prelude Therapeutics Chief Business Officer Sean Brusky reported direct ownership of 100,000 common shares in an initial Form 3 filing.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Prelude Therapeutics Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on March 19, 2026, and is solely responsible for the information contained therein.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260319:nNDL3XCsLy:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["PRLD","BK4139","BK4505"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2620269741","title":"Prelude Therapeutics management to meet with Citizens","url":"https://stock-news.laohu8.com/highlight/detail?id=2620269741","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2620269741?lang=en_us&edition=fundamental","pubTime":"2026-03-19 02:55","pubTimestamp":1773860115,"startTime":"0","endTime":"0","summary":"Meeting to be held in Boston on March 25 hosted by Citizens. Published first on TheFly – the ultimate source for real-time, market-moving breaking ...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/prelude-therapeutics-management-to-meet-with-citizens-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/prelude-therapeutics-management-to-meet-with-citizens-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","BK4505","PRLD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2620403382","title":"Prelude Therapeutics to present PRT13722 preclinical poster at AACR Annual Meeting 2026","url":"https://stock-news.laohu8.com/highlight/detail?id=2620403382","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2620403382?lang=en_us&edition=fundamental","pubTime":"2026-03-18 04:31","pubTimestamp":1773779480,"startTime":"0","endTime":"0","summary":"Prelude will present a poster on preclinical data for PRT13722 at the AACR Annual Meeting 2026, held April 17-22, 2026. The poster session “Proximity-Induced Drug Discovery 2” is scheduled for April 21, 2026 from 2:00 PM to 5:00 PM. On April 18, 2026, Norman Fultang will give a lecture in the educational session “ED08 - Chemistry to the Clinic Part 1 of 4: Next-Level Conjugates: Transforming Targeted Therapies.” The release includes a link to 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Oral KAT6A Selective Degrader at the 2026 AACR Annual Meeting","url":"https://stock-news.laohu8.com/highlight/detail?id=2620401972","media":"GlobeNewswire","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2620401972?lang=en_us&edition=fundamental","pubTime":"2026-03-18 04:31","pubTimestamp":1773779460,"startTime":"0","endTime":"0","summary":"WILMINGTON, Del., March  17, 2026 (GLOBE NEWSWIRE) -- Prelude Therapeutics Incorporated (Nasdaq: PRLD), a precision oncology company, today announced that a poster with preclinical data on the Company","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2026/03/17/3257688/0/en/Prelude-Therapeutics-Announces-Acceptance-of-Preclinical-Abstract-for-PRT13722-a-First-in-Class-Oral-KAT6A-Selective-Degrader-at-the-2026-AACR-Annual-Meeting.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4505","PRLD","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2618094438","title":"Prelude Therapeutics Is Maintained at Market Outperform by Citizens","url":"https://stock-news.laohu8.com/highlight/detail?id=2618094438","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618094438?lang=en_us&edition=fundamental","pubTime":"2026-03-11 19:47","pubTimestamp":1773229620,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/PRLD/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  March 11, 2026 07:47 ET (11:47 GMT)","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["PRLD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2618910798","title":"Prelude Therapeutics price target raised to $6 from $3 at Citizens","url":"https://stock-news.laohu8.com/highlight/detail?id=2618910798","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618910798?lang=en_us&edition=fundamental","pubTime":"2026-03-11 17:15","pubTimestamp":1773220525,"startTime":"0","endTime":"0","summary":"Citizens raised the firm’s price target on Prelude Therapeutics (PRLD) to $6 from $3 and keeps an Outperform rating on the shares following the Q4 ...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/prelude-therapeutics-price-target-raised-to-6-from-3-at-citizens-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/prelude-therapeutics-price-target-raised-to-6-from-3-at-citizens-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["PRLD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2618539979","title":"Prelude Therapeutics Reports 2025 Results, Highlights JAK2 Program","url":"https://stock-news.laohu8.com/highlight/detail?id=2618539979","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618539979?lang=en_us&edition=fundamental","pubTime":"2026-03-10 20:47","pubTimestamp":1773146868,"startTime":"0","endTime":"0","summary":"Prelude Therapeutics ( ($PRLD) ) has issued an update. Prelude Therapeutics reported full-year 2025 financial results on March 10, 2026, and outlin...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/company-announcements/prelude-therapeutics-reports-2025-results-highlights-jak2-program?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/company-announcements/prelude-therapeutics-reports-2025-results-highlights-jak2-program?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","BK4505","PRLD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2618593279","title":"Prelude Therapeutics Q4 EPS $(0.20) Misses $(0.03) Estimate, Sales $5.640M Miss $35.000M Estimate","url":"https://stock-news.laohu8.com/highlight/detail?id=2618593279","media":"Benzinga Earnings","labels":["dataReport","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618593279?lang=en_us&edition=fundamental","pubTime":"2026-03-10 19:38","pubTimestamp":1773142723,"startTime":"0","endTime":"0","summary":"Prelude Therapeutics (NASDAQ:PRLD) reported quarterly losses of $(0.20) per share which missed the analyst consensus estimate of $(0.03) by 566.67 percent. This is a 45.95 percent increase over losses of $(0.37) per","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.benzinga.com/news/earnings/26/03/51153016/prelude-therapeutics-q4-eps-0-20-misses-0-03-estimate-sales-5-640m-miss-35-000m-estimate","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["PRLD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2618793442","title":"Prelude Therapeutics reports $99.5 mln net loss for 2025","url":"https://stock-news.laohu8.com/highlight/detail?id=2618793442","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618793442?lang=en_us&edition=fundamental","pubTime":"2026-03-10 19:08","pubTimestamp":1773140892,"startTime":"0","endTime":"0","summary":"Prelude Therapeutics reports $99.5 mln net loss for 2025OverviewPrecision oncology firm reported a net loss of $99.5 mln for 2025Company received FDA clearance for IND application for PRT12396Cash run","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260310:nL1N3ZY0F4:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["PRLD","BK4139","BK4505"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2618949934","title":"BRIEF-Prelude Therapeutics FY EPS USD -1.29","url":"https://stock-news.laohu8.com/highlight/detail?id=2618949934","media":"Reuters","labels":["express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618949934?lang=en_us&edition=fundamental","pubTime":"2026-03-10 19:01","pubTimestamp":1773140505,"startTime":"0","endTime":"0","summary":"BRIEF-Prelude Therapeutics FY EPS USD -1.29\n\n\nMar 10 (Reuters) - Prelude Therapeutics FY operating expenses USD 116.706 million.\n\nFY income from operations USD -104.566 million\nFY net income USD -99.498 million","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260310:nPLX53BAA6:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4505","PRLD","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2618934912","title":"Press Release: Prelude Therapeutics Reports Full Year 2025 Financial Results and Provides Program Outlook for 2026","url":"https://stock-news.laohu8.com/highlight/detail?id=2618934912","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618934912?lang=en_us&edition=fundamental","pubTime":"2026-03-10 19:01","pubTimestamp":1773140460,"startTime":"0","endTime":"0","summary":"Received FDA clearance of Investigational New Drug application  for PRT12396, mutant-selective JAK2V617F inhibitor in the first quarter of 2026. Phase 1 study of PRT12396 in patients with polycythemia vera and myelofibrosis anticipated to initiate by Q2 2026. Preclinical development and IND enabling studies for PRT13722, highly-selective oral KAT6A degrader underway, and the Company intends to file the IND for PRT13722 in mid-2026 with Phase 1 study initiation anticipated in the 2 half of 2026. Current cash runway expected into second quarter of 2027 with $106 million in cash, cash equivalents, restricted cash and marketable securities as of December 31, 2025. The Phase 1 study of PRT12396 is an open-label, multi-center study in patients with high-risk PV and intermediate and high-risk MF.","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4109","BK4139","BK4585","ET","PRLD","BK4588","BK4581","LU2463526074.USD","BK4505","IND","BK4144","ASH","BK4561","BK4590"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2617417680","title":"Prelude Therapeutics Inc  expected to post a loss of 3 cents a share - Earnings Preview","url":"https://stock-news.laohu8.com/highlight/detail?id=2617417680","media":"Reuters","labels":["preview"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2617417680?lang=en_us&edition=fundamental","pubTime":"2026-03-06 20:59","pubTimestamp":1772801946,"startTime":"0","endTime":"0","summary":"Prelude Therapeutics Inc  expected to post a loss of3cents a share - Earnings Preview Prelude Therapeutics Inc PRLD.OQ PRLD.O is expected to  show a rise in quarterly revenue when it reports  results ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260306:nL8N3ZU19W:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"preview","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","PRLD","BK4505"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":20,"totalPage":3,"pageCount":3,"totalSize":52,"code":"91000000","status":"200"}]}}