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Pliant Therapeutics, Inc.

1.59

+0.11007.43%

Post-market: 1.59-0.0007-0.04%19:04 EDT

Volume:843.45K

Turnover:1.30M

Market Cap:97.60M

PE:-0.46

High:1.60

Open:1.46

Low:1.43

Close:1.48

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Overview Company News Filings

BRIEF-Pliant Therapeutics Provides Update On Beacon-IPF

Pliant Therapeutucs Shares Halted After Bexotegrast Phase 2b Trial Discontinued

Pliant Therapeutics Inc - Committed to Development of Other Clinical Assets Including Pln-101095 in Oncology

THOMSON REUTERS

Pliant Therapeutics Inc - Discontinues Beacon-Ipf Phase 2B Trial

THOMSON REUTERS

Blade Air Mobility Leads The Charge Among 3 US Penny Stocks

Simply Wall St.

TD Cowen Keeps Their Buy Rating on Pliant Therapeutics (PLRX)

Positive Outlook on Pliant Therapeutics Despite Trial Uncertainty

All You Need to Know About PLIANT THERAPT (PLRX) Rating Upgrade to Buy

Pliant Therapeutics Price Target Maintained With a $10.00/Share by Needham

Sector Update: Health Care Stocks Mixed Thursday Afternoon

MT Newswires Live

Optimistic Buy Recommendation Amid Pliant Therapeutics’ Trial Review and Stock Surge

Pliant Therapeutics to Assemble Expert Panel to Review BEACON-IPF Trial Data; Shares Jump

MT Newswires Live

Pliant Therapeutics Shares Rise After Board Recommendations for Bexotegrast

Pliant Therapeutics Announces Next Steps Following Dsmb Recommendation on Beacon-Ipf, a Phase 2B/3 Trial in Patients With Idiopathic Pulmonary Fibrosis

THOMSON REUTERS

Pliant Therapeutics Inc - Assembles Outside Expert Panel for Beacon-Ipf Trial Review

THOMSON REUTERS

Pliant Therapeutics downgraded to Neutral from Overweight at JPMorgan

Sector Update: Health Care Stocks Retreat Monday Afternoon

MT Newswires Live

Pliant Therapeutics Pauses Enrollment in BEACON-IPF Trial, Shares Take Steep Dive

Pliant Therapeutics Shares Tumble Amid Analyst Downgrades Following Study Suspension

MT Newswires Live

Pliant Therapeutics Cut to Hold From Buy by Canaccord Genuity

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Pliant Therapeutics Inc PLRX.O:PLIANT THERAPEUTICS PROVIDES UPDATE ON BEACON-IPF, A PHASE 2B/3 TRIAL IN PATIENTS WITH IDIOPAT","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250303:nTUAB0YXYR:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4007","PLRX"],"gpt_icon":0},{"id":"2516371126","title":"Pliant Therapeutucs Shares Halted After Bexotegrast Phase 2b Trial Discontinued","url":"https://stock-news.laohu8.com/highlight/detail?id=2516371126","media":"Dow Jones","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2516371126?lang=en_us&edition=fundamental","pubTime":"2025-03-03 22:47","pubTimestamp":1741013220,"startTime":"0","endTime":"0","summary":"Pliant Therapeutics shares were halted in early morning trading after falling 25% to $2.57, after the company said it is discontinuing a phase 2b trial for bexotegrast in patients with idiopathic pulmonary fibrosis.The discontinuation follows a prespecified data review and recommendation by an independent Data Safety Monitoring Board, as well as a secondary review and recommendation by an outside expert panel.The late-stage biopharmaceutical company said that while an imbalance in unadjudicated IPF-related adverse events between the treatment and placebo groups led to the discontinuation of the trial, early evidence of efficacy on the forced vital capacity endpoint was also observed.Overall, the percentage of IPF-related adverse events in both dose groups was comparable--about 10%.The company plans to analyze the complete data from the trial and evaluate next steps for bexotegrast's development, including additional dose-ranging Phase 2b studies with lower doses in pulmonary fibrosis.","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":"Pliant Therapeutucs Shares Halted After Bexotegrast Phase 2b Trial Discontinued","news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["PLRX","BK4007"],"gpt_icon":0},{"id":"2516631123","title":"Pliant Therapeutics Inc - 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Penny stocks, often representing smaller or newer companies, continue to intrigue those looking beyond established giants for potential growth. Despite their historical reputation as speculative bets, some penny stocks today boast robust financial health and present intriguing possibilities for investors seeking unique opportunities.Get an in-depth perspective on Blade Air Mobility's performance by reading our balance sheet health report here.Gain insights into Blade Air Mobility's outlook and expected performance with our report on the company's earnings estimates.Overview: Nautilus Biotechnology, Inc. is a development stage life sciences company focused on creating platform technology to quantify and unlock the complexity of the proteome, with a market cap of $214.71 million.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/blade-air-mobility-leads-charge-131345868.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["SB","BK4563","AIRI","BK4187","PHX","BLDE","PLRX","BK4209","PVL","BK4021","NAUT","BLDEW","BABB","BK4213"],"gpt_icon":0},{"id":"2512152624","title":"TD Cowen Keeps Their Buy Rating on Pliant Therapeutics (PLRX)","url":"https://stock-news.laohu8.com/highlight/detail?id=2512152624","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2512152624?lang=en_us&edition=fundamental","pubTime":"2025-02-18 21:06","pubTimestamp":1739883998,"startTime":"0","endTime":"0","summary":"TD Cowen analyst Ritu Baral maintained a Buy rating on Pliant Therapeutics (PLRX – Research Report) today. The company’s shares closed last Friday ...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/td-cowen-keeps-their-buy-rating-on-pliant-therapeutics-plrx?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate","earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/td-cowen-keeps-their-buy-rating-on-pliant-therapeutics-plrx?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["PLRX","TD","COWN"],"gpt_icon":0},{"id":"2512911522","title":"Positive Outlook on Pliant Therapeutics Despite Trial Uncertainty","url":"https://stock-news.laohu8.com/highlight/detail?id=2512911522","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2512911522?lang=en_us&edition=fundamental","pubTime":"2025-02-17 16:15","pubTimestamp":1739780155,"startTime":"0","endTime":"0","summary":"Leerink Partners analyst Faisal Khurshid has maintained their bullish stance on PLRX stock, giving a Buy rating on February 13. Faisal Khurshid has...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/ratings/positive-outlook-on-pliant-therapeutics-despite-trial-uncertainty?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/ratings/positive-outlook-on-pliant-therapeutics-despite-trial-uncertainty?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["LENZ","BK4007","BK4139","PLRX"],"gpt_icon":0},{"id":"2511468056","title":"All You Need to Know About PLIANT THERAPT (PLRX) Rating Upgrade to Buy","url":"https://stock-news.laohu8.com/highlight/detail?id=2511468056","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2511468056?lang=en_us&edition=fundamental","pubTime":"2025-02-15 01:00","pubTimestamp":1739552412,"startTime":"0","endTime":"0","summary":"Pliant Therapeutics, Inc.  could be a solid choice for investors given its recent upgrade to a Zacks Rank #2 . This rating change essentially reflects an upward trend in earnings estimates -- one of the most powerful forces impacting stock prices.A company's changing earnings picture is at the core of the Zacks rating. The system tracks the Zacks Consensus Estimate -- the consensus measure of EPS estimates from the sell-side analysts covering the stock -- for the current and following years.Individual investors often find it hard to make decisions based on rating upgrades by Wall Street analysts, since these are mostly driven by subjective factors that are hard to see and measure in real time. In these situations, the Zacks rating system comes in handy because of the power of a changing earnings picture in determining near-term stock price movements.Therefore, the Zacks rating upgrade for PLIANT THERAPT basically reflects positivity about its earnings outlook that could translate into ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/know-pliant-therapt-plrx-rating-170012800.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["PLRX"],"gpt_icon":1},{"id":"2511666697","title":"Pliant Therapeutics Price Target Maintained With a $10.00/Share by Needham","url":"https://stock-news.laohu8.com/highlight/detail?id=2511666697","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2511666697?lang=en_us&edition=fundamental","pubTime":"2025-02-14 19:01","pubTimestamp":1739530860,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/PLRX/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  February 14, 2025 06:01 ET (11:01 GMT)","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LENZ","PLRX"],"gpt_icon":0},{"id":"2511311579","title":"Sector Update: Health Care Stocks Mixed Thursday Afternoon","url":"https://stock-news.laohu8.com/highlight/detail?id=2511311579","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2511311579?lang=en_us&edition=fundamental","pubTime":"2025-02-14 03:02","pubTimestamp":1739473343,"startTime":"0","endTime":"0","summary":"Health care stocks were mixed Thursday afternoon with the NYSE Health Care Index easing 0.1% and the Health Care Select Sector SPDR Fund  increasing 0.1%.The iShares Biotechnology ETF  rose 0.6%.In sector news, the US Senate confirmed Robert F. Kennedy Jr. as head of the US Department of Health and Human Services.In corporate news, Pliant Therapeutics'  shares surged 25% after the company started assembling an external expert panel to evaluate unblinded data from the phase 2b trial of bexotegrast in people with idiopathic pulmonary fibrosis.GE Healthcare Technologies  shares jumped 9.3% after the company reported higher Q4 adjusted earnings and revenue.Aardvark Therapeutics  shares debuted on Nasdaq with an opening price of $15.18, below the initial public offering price of $16. The stock fell 20% in recent trading.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK4007","XLV","BK4581","BK4585","IBB","LU0124676726.USD","GEHC","LU0689626769.HKD","PLRX","AARD","BK4588","BK4082"],"gpt_icon":0},{"id":"2511575923","title":"Optimistic Buy Recommendation Amid Pliant Therapeutics’ Trial Review and Stock Surge","url":"https://stock-news.laohu8.com/highlight/detail?id=2511575923","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2511575923?lang=en_us&edition=fundamental","pubTime":"2025-02-14 02:15","pubTimestamp":1739470516,"startTime":"0","endTime":"0","summary":"Analyst Joseph Stringer from Needham maintained a Buy rating on Pliant Therapeutics (PLRX – Research Report) and keeping the price target at $10.00...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/ratings/optimistic-buy-recommendation-amid-pliant-therapeutics-trial-review-and-stock-surge?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/ratings/optimistic-buy-recommendation-amid-pliant-therapeutics-trial-review-and-stock-surge?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["PLRX","BK4007","LENZ","BK4139"],"gpt_icon":0},{"id":"2511527645","title":"Pliant Therapeutics to Assemble Expert Panel to Review BEACON-IPF Trial Data; Shares Jump","url":"https://stock-news.laohu8.com/highlight/detail?id=2511527645","media":"MT Newswires Live","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2511527645?lang=en_us&edition=fundamental","pubTime":"2025-02-14 00:15","pubTimestamp":1739463356,"startTime":"0","endTime":"0","summary":"Pliant Therapeutics'  shares rose by than 32% in recent Thursday trading after the company said it has begun assembling an external expert panel to evaluate unblinded data from the ongoing BEACON-IPF Phase 2b trial of bexotegrast in patients with idiopathic pulmonary fibrosis.This move comes after the trial's independent Data Safety Monitoring Board recommended pausing enrollment and dosing, the company said, adding that it has been unable to identify the rationale behind the DSMB's recommendation after reviewing blinded data.The panel, consisting of pulmonary disease and biostatistics experts, will offer an independent recommendation and later collaborate with an expanded DSMB to reach a consensus on BEACON-IPF. The process is expected to conclude in 2 to 4 weeks.Following the DSMB's recommendation, Pliant voluntarily paused enrollment and dosing in the BEACON-IPF trial while remaining blinded to preserve data integrity of the BEACON-IPF 2b and its potential as a registrational study,","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK4139","PLRX","LENZ","BK4007"],"gpt_icon":0},{"id":"2511521154","title":"Pliant Therapeutics Shares Rise After Board Recommendations for Bexotegrast","url":"https://stock-news.laohu8.com/highlight/detail?id=2511521154","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2511521154?lang=en_us&edition=fundamental","pubTime":"2025-02-13 23:27","pubTimestamp":1739460420,"startTime":"0","endTime":"0","summary":"Pliant Therapeutics shares were up 23% to $3.34 after the company said an independent Data Safety Monitoring Board is allowing it to begin the assembly of an outside expert panel to review unblinded data from an ongoing Phase 2b trial of bexotegrast in patients with idiopathic pulmonary fibrosis.The biopharmaceutical company said the panel, consisting of experts in pulmonary diseases and biostatistics, will provide an independent recommendation to Pliant regarding the trial.The panel will serve as part of an expanded DSMB with the goal to reach a consensus recommendation regarding the trial. The decision to assemble the outside panel was taken as the company hasn't been able, through review of blinded data, to determine the rationale for the DSMB's recommendation to pause enrollment and dosing in the trial.Pliant expects this process to conclude in two to four weeks.Following the DSMB's previously announced recommendation, Pliant voluntarily paused enrollment and dosing in the clinical","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4007","BK4139","LENZ","PLRX"],"gpt_icon":1},{"id":"2511425955","title":"Pliant Therapeutics Announces Next Steps Following Dsmb Recommendation on Beacon-Ipf, a Phase 2B/3 Trial in Patients With Idiopathic Pulmonary Fibrosis","url":"https://stock-news.laohu8.com/highlight/detail?id=2511425955","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2511425955?lang=en_us&edition=fundamental","pubTime":"2025-02-13 21:00","pubTimestamp":1739451600,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250213:nTUA3ZJY9X:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4007","PLRX"],"gpt_icon":0},{"id":"2511291542","title":"Pliant Therapeutics Inc - Assembles Outside Expert Panel for Beacon-Ipf Trial Review","url":"https://stock-news.laohu8.com/highlight/detail?id=2511291542","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2511291542?lang=en_us&edition=fundamental","pubTime":"2025-02-13 21:00","pubTimestamp":1739451600,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250213:nTUA3ZJY9X:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4007","PLRX"],"gpt_icon":0},{"id":"2510382284","title":"Pliant Therapeutics downgraded to Neutral from Overweight at JPMorgan","url":"https://stock-news.laohu8.com/highlight/detail?id=2510382284","media":"TipRanks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2510382284?lang=en_us&edition=fundamental","pubTime":"2025-02-11 22:11","pubTimestamp":1739283075,"startTime":"0","endTime":"0","summary":"JPMorgan downgraded Pliant Therapeutics  to Neutral from Overweight without a price target after the company announced a voluntary pause to the enrollment, and dosing, of its Phase 2b BEACON trial based on the recommendation of the Data and Safety Monitoring Board. The news “portends a material fundamental setback for the program, either for reasons of safety or futile activity,” the analyst tells investors in a research note. The firm says that with little pipeline value beyond bexotograst, it sees share downside to $3-$4 on the update, in line with the company’s year-end estimated cash. The stock in premarket trading is down 60%, or $4.780, to $3.09.Leverage the power of TipRanks' Smart Score, a data-driven tool to help you uncover top performing stocks and make informed investment decisions.Monitor your stock picks and compare them to top Wall Street Analysts' recommendations with  Your Smart Portfolio. Pliant Therapeutics downgraded to Perform from Outperform at Oppenheimer. Pliant","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/pliant-therapeutics-downgraded-neutral-overweight-141115253.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/pliant-therapeutics-downgraded-neutral-overweight-141115253.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LENZ","PLRX"],"gpt_icon":0},{"id":"2510899533","title":"Sector Update: Health Care Stocks Retreat Monday Afternoon","url":"https://stock-news.laohu8.com/highlight/detail?id=2510899533","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2510899533?lang=en_us&edition=fundamental","pubTime":"2025-02-11 03:02","pubTimestamp":1739214155,"startTime":"0","endTime":"0","summary":"Health care stocks were lower Monday afternoon, with the NYSE Health Care Index and the Health Care Select Sector SPDR Fund  each shedding about 0.4%.The iShares Biotechnology ETF  fell 1%.In corporate news, Spingworks Therapeutics  shares jumped over 36%. The company is in advanced talks to be acquired by Merck KGaA, Reuters reported.Axsome Therapeutics  shares rose 21% after the firm said it agreed to a settlement deal with Teva  to resolve patent litigation over its Auvelity product. Teva was down 0.8%.Pliant Therapeutics  shares fell 59% after the firm paused enrollment and dosing in a phase 2b trial of bexotegrast in idiopathic pulmonary fibrosis patients. Several analysts  downgraded the stock following the announcement.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["AXSM","BK4505","BK4581","XLV","PLRX","BK4566","BK4007","TEVA","BK4557","BK4559","BK4584","SWTX","BK4585","BK4596","BK4588","BK4139","IBB"],"gpt_icon":0},{"id":"2510895494","title":"Pliant Therapeutics Pauses Enrollment in BEACON-IPF Trial, Shares Take Steep Dive","url":"https://stock-news.laohu8.com/highlight/detail?id=2510895494","media":"GuruFocus.com","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2510895494?lang=en_us&edition=fundamental","pubTime":"2025-02-11 02:15","pubTimestamp":1739211344,"startTime":"0","endTime":"0","summary":"Pliant Therapeutics  shares tumbled 58.8% to $3.21 as of 12:40 p.m. ET on Monday, following a 34.8% decline on Friday, after the company announced a voluntary pause in enrollment and dosing for its BEACON-IPF Phase 2b trial.GuruFocus has detected 3 Warning Signs with PLRX.The independent Data Safety Monitoring Board of the trial is cited as the reason for the choice.1 integrins, proteins linked in fibrosis, Bexotegrast is an oral small-molecule inhibitor being studied. The U.S. Food and Drug Administration has assigned it Fast Track and Orphan Drug designations; the European Medicines Agency has assigned it Orphan Drug status. The BEACON-IPF study is assessing the medication as a possible therapy for the progressive lung illness known as idiopathic pulmonary fibrosis, for which there are few therapeutic choices.Pliant said it is still dedicated to working with authorities and the DSMB to decide the best course ahead, but it did not provide a restarting enrollment timetable. As addition","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/pliant-therapeutics-pauses-enrollment-beacon-181544794.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4139","PLRX","BK4007","LENZ"],"gpt_icon":0},{"id":"2510186267","title":"Pliant Therapeutics Shares Tumble Amid Analyst Downgrades Following Study Suspension","url":"https://stock-news.laohu8.com/highlight/detail?id=2510186267","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2510186267?lang=en_us&edition=fundamental","pubTime":"2025-02-11 00:24","pubTimestamp":1739204680,"startTime":"0","endTime":"0","summary":"Pliant Therapeutics  shares fell 60% in recent Monday trading after several investment firms downgraded their ratings on the company following its announcement late Friday that it has suspended enrollment and dosing in a phase 2b trial of bexotegrast for idiopathic pulmonary fibrosis.RBC downgraded Pliant to sector perform from outperform and cut its price target to $4 from $45, Oppenheimer downgraded the company to perform from outperform, HC Wainwright downgraded it to neutral from buy, Citigroup downgraded it to neutral from buy, with a $4 price target, and Wells Fargo downgraded it to equalweight from overweight, with a $4 price target.Price: 3.09, Change: -4.70, Percent Change: 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