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Pliant Therapeutics, Inc.

1.14

+0.05004.59%

Post-market: 1.150.0100+0.88%18:17 EST

Volume:715.05K

Turnover:818.52K

Market Cap:70.05M

PE:-0.40

High:1.19

Open:1.12

Low:1.11

Close:1.09

52wk High:11.96

52wk Low:1.09

Shares:61.45M

Float Shares:55.57M

Volume Ratio:0.74

T/O Rate:1.29%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-2.8668

EPS(LYR):-3.4739

ROE:-64.27%

ROA:-32.87%

PB:0.35

PE(LYR):-0.33

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News

Pliant Therapeutics Unveils Data on Oral Integrin Inhibitor for ICI-Resistant Tumors

Pliant Therapeutics Files Initial Beneficial Ownership Statement for Chief Operating Officer Minnie Kuo

Pliant Therapeutics Appoints Minnie Kuo as Chief Operating Officer

Pliant Therapeutics Inc - Terminates Cmo ÉRic Lefebvre Effective December 15 - SEC Filing

THOMSON REUTERS

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The lead program, PLN-101095, is an oral small molecule inhibitor targeting αvβ8 and αvβ1 integrins for the treatment of immune checkpoint inhibitor -resistant solid tumors. In the Phase 1 study, four clinical responders—including one complete response and three partial responses—were observed among heavily pre-treated patients at the highest dose levels, with a median treatment duration of 15 months for responders. The compound demonstrated dose-dependent plasma exposure and was well tolerated. Pliant is advancing a Phase 1b dose expansion to further assess efficacy in non-small cell lung cancer and other tumor types. Additionally, the company is developing a cell-specific drug delivery platform for siRNA payloads, with broad applicability across multiple disease areas. Pliant reports a strong cash position to fund operations through 2028. You can access the f","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260127:nNDL8jpVpF:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["PLRX","BK4007"],"gpt_icon":0},{"id":"2593453239","title":"Pliant Therapeutics Files Initial Beneficial Ownership Statement for Chief Operating Officer Minnie Kuo","url":"https://stock-news.laohu8.com/highlight/detail?id=2593453239","media":"Reuters","labels":["executive","shareholding","insiderTrades"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2593453239?lang=en_us&edition=fundamental","pubTime":"2025-12-23 06:03","pubTimestamp":1766441001,"startTime":"0","endTime":"0","summary":"Pliant Therapeutics Inc. has filed an initial statement of beneficial ownership  with the U.S. Securities and Exchange Commission. The filing lists Minnie Kuo, Chief Operating Officer of the company, as the beneficial owner. The full filing can be accessed through the link below.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Pliant Therapeutics Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on December 22, 2025, and is solely responsible for the information contained therein.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251222:nNDLcntf5:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":"Pliant Therapeutics Files Initial Beneficial Ownership Statement for Chief Operating Officer Minnie Kuo","news_tag":"executive,shareholding,insiderTrades","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4007","PLRX"],"gpt_icon":0},{"id":"2592995830","title":"Pliant Therapeutics Appoints Minnie Kuo as Chief Operating Officer","url":"https://stock-news.laohu8.com/highlight/detail?id=2592995830","media":"Reuters","labels":["executive"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2592995830?lang=en_us&edition=fundamental","pubTime":"2025-12-17 06:06","pubTimestamp":1765922771,"startTime":"0","endTime":"0","summary":"Pliant Therapeutics Inc. has appointed Minnie Kuo as Chief Operating Officer, effective immediately. Kuo joined the company in September 2023 as Chief Development Officer and has over 20 years of experience in biotechnology and pharmaceuticals, with prior leadership roles at Vir Biotechnology, Nektar Therapeutics, and Gilead Sciences.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Pliant Therapeutics Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on December 16, 2025, and is solely responsible for the information contained therein.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251216:nNDL3FFM7N:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"executive","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["NKTR","GILD","PLRX","LU1585245621.USD","LU0109394709.USD","IE0002270589.USD","SG9999015986.USD","BK4566","LU1430594728.SGD","LU1674673691.USD","SG9999015952.SGD","IE00B3T34201.USD","BK4532","LU1778281490.HKD","BK4583","LU2468319806.SGD","LU1571399168.USD","LU2324357040.USD","LU0882574055.USD","BK4535","LU0320765992.SGD","BK4568","IE00BZ1G4Q59.USD","LU1839511570.USD","LU2087621335.USD","BK4007","LU0289739699.SGD","LU1066051498.USD","LU0114720955.EUR","LU0234570918.USD","BK4578","LU1066053197.SGD","SG9999015945.SGD","BK4585","LU2089984988.USD","VIR","LU0889565916.HKD","IE00B19Z3581.USD","LU0823416689.USD","LU0058720904.USD","BK4139","IE00B7SZLL34.SGD","IE00BKVL7J92.USD","BK4588","BK4550","IE00B19Z3B42.SGD","LU1674673428.USD","IE00BSNM7G36.USD","SG9999015978.USD"],"gpt_icon":0},{"id":"2590661073","title":"Pliant Therapeutics Inc - Terminates Cmo ÉRic Lefebvre Effective December 15 - SEC Filing","url":"https://stock-news.laohu8.com/highlight/detail?id=2590661073","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2590661073?lang=en_us&edition=fundamental","pubTime":"2025-12-09 05:42","pubTimestamp":1765230176,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251208:nFWN3XE1BI:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["PLRX","BK4007"],"gpt_icon":0}],"pageSize":4,"totalPage":7,"pageCount":1,"totalSize":25,"code":"91000000","status":"200"}],"@#url:\"https://hq.skytigris.cn/market/plate/belongs/PLRX\",params:#limit:6,delay:false,,,undefined,":[]}}