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Nuvalent, Inc.

74.68

-1.4000-1.84%

Volume:20.20K

Turnover:1.52M

Market Cap:5.38B

PE:-15.24

High:76.07

Open:75.75

Low:74.68

Close:76.08

52wk High:113.51

52wk Low:55.54

Shares:72.10M

Float Shares:41.56M

Volume Ratio:0.16

T/O Rate:0.05%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-4.8991

EPS(LYR):-3.9265

ROE:-43.55%

ROA:-26.37%

PB:5.73

PE(LYR):-19.02

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Overview Company News Filings

Nuvalent Initiated at Overweight by Piper Sandler

Nuvalent Inc. Advances with FDA's Real-Time Oncology Review for Zidesamtinib in ROS1-Positive NSCLC Patients

Nuvalent (NUVL) Receives a Buy from J.P. Morgan

Nuvalent (NUVL) Receives a Buy from UBS

H.C. Wainwright Keeps Their Buy Rating on Nuvalent (NUVL)

Nuvalent (NUVL) Gets a Buy from Barclays

Nuvalent’s Promising Drug Pipeline and Strategic Trials Drive Buy Rating

Nuvalent (NUVL) Q2 R&D Up 65%

Earnings Flash (NUVL) Nuvalent Posts Q2 Net Loss Per Share $1.39, vs. FactSet Est of $1.22

MT Newswires Live

Nuvalent Q2 EPS $(1.39) Misses $(1.22) Estimate

Nuvalent Inc. Reports Q2 2025 Net Loss of $99.7M; Cash Position Strong at $1 Billion

Nuvalent Highlights Pipeline and Business Achievements, Reiterates Key Anticipated Milestones, and Reports Second Quarter 2025 Financial Results

THOMSON REUTERS

Nuvalent Q2 Income From Operations USD -104.571 Million

THOMSON REUTERS

Analysts Offer Insights on Healthcare Companies: Avantor (AVTR), Nuvalent (NUVL) and Alphatec Holdings (ATEC)

Chief Development Officer Darlene Noci Reports Disposal of Nuvalent Inc. Common Shares

Nuvalent’s Accelerated ALKAZAR Trial Progress and Strong Financials Justify Buy Rating

Nuvalent doses first patient in Alkazar trial

BRIEF-Nuvalent Announces Initiation Of Alkazar Phase 3 Randomized

Nuvalent Inc. Launches Phase 3 ALKAZAR Trial Evaluating Neladalkib for ALK-positive NSCLC Patients

James Richard Porter, President and CEO of Nuvalent Inc., Reports Disposal of Common Shares

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Initiated at Overweight by Piper Sandler","url":"https://stock-news.laohu8.com/highlight/detail?id=2560196495","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2560196495?lang=en_us&edition=fundamental","pubTime":"2025-08-19 20:00","pubTimestamp":1755604800,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/NUVL/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  August 19, 2025 08:00 ET (12:00 GMT)","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["NUVL"],"gpt_icon":0},{"id":"2559198553","title":"Nuvalent Inc. Advances with FDA's Real-Time Oncology Review for Zidesamtinib in ROS1-Positive NSCLC Patients","url":"https://stock-news.laohu8.com/highlight/detail?id=2559198553","media":"Reuters","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2559198553?lang=en_us&edition=fundamental","pubTime":"2025-08-14 01:07","pubTimestamp":1755104837,"startTime":"0","endTime":"0","summary":"Nuvalent Inc., a clinical-stage biopharmaceutical company, has initiated its rolling New Drug Application  submission for zidesamtinib, a novel ROS1-selective inhibitor, for TKI pre-treated patients with advanced ROS1-positive non-small cell lung cancer . The U.S. Food and Drug Administration  has agreed to accept the NDA for participation in the Real-Time Oncology Review  pilot program. This program allows for earlier submission of topline efficacy and safety results, potentially expediting the FDA's evaluation process. Completion of the NDA submission is targeted for the third quarter of 2025. Nuvalent continues to engage with the FDA on potential line-agnostic expansion opportunities, marking a significant step in advancing treatment options for patients with ROS1-positive NSCLC.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for infor","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250813:nNDL6rRPtK:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","BK4539","NUVL"],"gpt_icon":0},{"id":"2558644194","title":"Nuvalent (NUVL) Receives a Buy from J.P. 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The company’s shares closed yest...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/nuvalent-nuvl-receives-a-buy-from-j-p-morgan-blurbs?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/nuvalent-nuvl-receives-a-buy-from-j-p-morgan-blurbs?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4504","BK4534","LU2023251221.USD","IE00BZ1G4Q59.USD","LU0912757837.SGD","LU1244550494.USD","LU0006306889.USD","BK4539","BK4585","LU2089284900.SGD","LU2111349929.HKD","LU1162221912.USD","LU0267386448.USD","LU2028103732.USD","LU0795875169.SGD","LU2271345857.HKD","LU1989772923.USD","LU2357305700.SGD","IE00BKVL7J92.USD","LU0225283273.USD","NUVL","LU1732799900.SGD","LU0158827781.USD","BK4588","LU0314104364.USD","LU2347655156.SGD","BK4581","LU1244550221.USD","BK4127","LU0158827948.USD","BK4516","LU0795875086.SGD","LU0106831901.USD","LU0971096721.USD","LU0234570918.USD","LU1732800096.USD","LU0106261372.USD","LU1720051017.SGD","LU1244550577.SGD","LU1363072403.SGD","LU1074936037.SGD","LU1720051108.HKD","LU0320765646.SGD","LU0098860793.USD","LU1989772840.SGD","LU1668664300.SGD","LU2133065610.SGD","LU2089283258.USD","LU1548497426.USD","BK4139"],"gpt_icon":0},{"id":"2558366896","title":"Nuvalent (NUVL) Receives a Buy from UBS","url":"https://stock-news.laohu8.com/highlight/detail?id=2558366896","media":"TIPRANKS","labels":["executive"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2558366896?lang=en_us&edition=fundamental","pubTime":"2025-08-11 20:35","pubTimestamp":1754915719,"startTime":"0","endTime":"0","summary":"UBS analyst David Dai maintained a Buy rating on Nuvalent today and set a price target of $114.00. The company’s shares closed last Friday at $74.1...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/nuvalent-nuvl-receives-a-buy-from-ubs-blurbs?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/nuvalent-nuvl-receives-a-buy-from-ubs-blurbs?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"executive","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","BK4539","NUVL"],"gpt_icon":0},{"id":"2557523307","title":"H.C. 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The co...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/h-c-wainwright-keeps-their-buy-rating-on-nuvalent-nuvl-blurbs?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate","earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/h-c-wainwright-keeps-their-buy-rating-on-nuvalent-nuvl-blurbs?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"express","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["NUVL"],"gpt_icon":0},{"id":"2557336544","title":"Nuvalent (NUVL) Gets a Buy from Barclays","url":"https://stock-news.laohu8.com/highlight/detail?id=2557336544","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2557336544?lang=en_us&edition=fundamental","pubTime":"2025-08-08 16:56","pubTimestamp":1754643387,"startTime":"0","endTime":"0","summary":"Barclays analyst Peter Lawson maintained a Buy rating on Nuvalent today and set a price target of $100.00. The company’s shares closed yesterday at...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/nuvalent-nuvl-gets-a-buy-from-barclays-blurbs?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/nuvalent-nuvl-gets-a-buy-from-barclays-blurbs?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["NUVL","BK4539","BK4139"],"gpt_icon":0},{"id":"2557595585","title":"Nuvalent’s Promising Drug Pipeline and Strategic Trials Drive Buy Rating","url":"https://stock-news.laohu8.com/highlight/detail?id=2557595585","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2557595585?lang=en_us&edition=fundamental","pubTime":"2025-08-08 03:25","pubTimestamp":1754594741,"startTime":"0","endTime":"0","summary":"TD Cowen analyst Marc Frahm has maintained their bullish stance on NUVL stock, giving a Buy rating today. Marc Frahm has given his Buy rating due t...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/ratings/nuvalents-promising-drug-pipeline-and-strategic-trials-drive-buy-rating-ratings?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/ratings/nuvalents-promising-drug-pipeline-and-strategic-trials-drive-buy-rating-ratings?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["NUVL"],"gpt_icon":0},{"id":"2557563762","title":"Nuvalent (NUVL) Q2 R&D Up 65%","url":"https://stock-news.laohu8.com/highlight/detail?id=2557563762","media":"Motley Fool","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2557563762?lang=en_us&edition=fundamental","pubTime":"2025-08-07 20:18","pubTimestamp":1754569080,"startTime":"0","endTime":"0","summary":"R&D spending increased 64.6% year over year on a GAAP basis as the company advanced late-stage cancer drug trials and prepared for product launches.Cash, cash equivalents, and marketable securities totaled $1.01 billion as of June 30, 2025, providing a runway into 2028.","market":"fut","thumbnail":"https://g.foolcdn.com/image/?url=https%3A%2F%2Fcdn.content.foolcdn.com%2Fimages%2F1umn9qeh%2Fproduction%2F2e67fde4d458002cf59f26acf09dd58f97b62ce0-1024x1024.png&op=resize&w=165&h=104","type":0,"news_type":0,"thumbnails":["https://g.foolcdn.com/image/?url=https%3A%2F%2Fcdn.content.foolcdn.com%2Fimages%2F1umn9qeh%2Fproduction%2F2e67fde4d458002cf59f26acf09dd58f97b62ce0-1024x1024.png&op=resize&w=165&h=104"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.fool.com/data-news/2025/08/07/nuvalent-nuvl-q2-rd-up-65/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"fool_stock","symbols":["NUVL","BK4139","BK4539"],"gpt_icon":0},{"id":"2557548155","title":"Earnings Flash (NUVL) Nuvalent Posts Q2 Net Loss Per Share $1.39, vs. FactSet Est of $1.22","url":"https://stock-news.laohu8.com/highlight/detail?id=2557548155","media":"MT Newswires Live","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2557548155?lang=en_us&edition=fundamental","pubTime":"2025-08-07 18:47","pubTimestamp":1754563640,"startTime":"0","endTime":"0","summary":"Earnings Flash (NUVL) Nuvalent Posts Q2 Net Loss Per Share $1.39, vs. FactSet Est of $1.22","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["NUVL"],"gpt_icon":0},{"id":"2557255163","title":"Nuvalent Q2 EPS $(1.39) Misses $(1.22) Estimate","url":"https://stock-news.laohu8.com/highlight/detail?id=2557255163","media":"Benzinga","labels":["express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2557255163?lang=en_us&edition=fundamental","pubTime":"2025-08-07 18:40","pubTimestamp":1754563212,"startTime":"0","endTime":"0","summary":"Nuvalent (NASDAQ:NUVL) reported quarterly losses of $(1.39) per share which missed the analyst consensus estimate of $(1.22) by 13.65 percent. This is a 57.95 percent decrease over losses of $(0.88) per share from the","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.benzinga.com/news/earnings/25/08/46956743/nuvalent-q2-eps-1-39-misses-1-22-estimate","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["NUVL"],"gpt_icon":0},{"id":"2557559005","title":"Nuvalent Inc. Reports Q2 2025 Net Loss of $99.7M; Cash Position Strong at $1 Billion","url":"https://stock-news.laohu8.com/highlight/detail?id=2557559005","media":"Reuters","labels":["dataReport","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2557559005?lang=en_us&edition=fundamental","pubTime":"2025-08-07 18:31","pubTimestamp":1754562677,"startTime":"0","endTime":"0","summary":"Nuvalent, Inc. , a clinical-stage biopharmaceutical company, has released its financial results for the second quarter of 2025. The company reported a net loss of $99.7 million for the period. Research and development expenses reached $80.9 million, while general and administrative expenses were $23.7 million. As of June 30, 2025, Nuvalent's cash, cash equivalents, and marketable securities totaled $1.0 billion, with the company projecting this cash position will be sufficient to fund its operating plan into 2028. In terms of business operations, Nuvalent announced the promotion of Jason Waters to Senior Vice President, Commercial, to support the company's transition towards becoming a fully integrated, commercial-stage biopharmaceutical organization. The company also highlighted several key pipeline achievements, including the initiation of a rolling NDA submission for zidesamtinib for advanced ROS1-positive NSCLC and the start of the ALKAZAR Phase 3 trial for neladalkib in front-line","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250807:nNDL63j4GJ:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4539","NUVL","BK4139"],"gpt_icon":0},{"id":"2557597155","title":"Nuvalent Highlights Pipeline and Business Achievements, Reiterates Key Anticipated Milestones, and Reports Second Quarter 2025 Financial Results","url":"https://stock-news.laohu8.com/highlight/detail?id=2557597155","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2557597155?lang=en_us&edition=fundamental","pubTime":"2025-08-07 18:30","pubTimestamp":1754562619,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250807:nTUA7JQHPC:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4539","BK4139","NUVL"],"gpt_icon":0},{"id":"2557559774","title":"Nuvalent Q2 Income From Operations USD -104.571 Million","url":"https://stock-news.laohu8.com/highlight/detail?id=2557559774","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2557559774?lang=en_us&edition=fundamental","pubTime":"2025-08-07 18:30","pubTimestamp":1754562618,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250807:nPLX479B2C:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4539","NUVL","BK4139"],"gpt_icon":0},{"id":"2556487999","title":"Analysts Offer Insights on Healthcare Companies: Avantor (AVTR), Nuvalent (NUVL) and Alphatec Holdings (ATEC)","url":"https://stock-news.laohu8.com/highlight/detail?id=2556487999","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2556487999?lang=en_us&edition=fundamental","pubTime":"2025-08-04 09:20","pubTimestamp":1754270408,"startTime":"0","endTime":"0","summary":"There’s a lot to be optimistic about in the Healthcare sector as 3 analysts just weighed in on Avantor (AVTR – Research Report), Nuvalent (NUVL – R...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/analysts-offer-insights-on-healthcare-companies-avantor-avtr-nuvalent-nuvl-and-alphatec-holdings-atec-blurbs?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/analysts-offer-insights-on-healthcare-companies-avantor-avtr-nuvalent-nuvl-and-alphatec-holdings-atec-blurbs?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4137","BK4539","NUVL","AVTR","ATEC","BK4082","HCSG","BK4121","BK4139"],"gpt_icon":0},{"id":"2556457698","title":"Chief Development Officer Darlene Noci Reports Disposal of Nuvalent Inc. Common Shares","url":"https://stock-news.laohu8.com/highlight/detail?id=2556457698","media":"Reuters","labels":["shareholding","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2556457698?lang=en_us&edition=fundamental","pubTime":"2025-08-02 04:31","pubTimestamp":1754080263,"startTime":"0","endTime":"0","summary":"Darlene Noci, Chief Development Officer at Nuvalent Inc., reported a disposal of common shares of the company. The full filing can be accessed through the link below.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Nuvalent Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on August 01, 2025, and is solely responsible for the information contained therein.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250801:nNDL6zfQXT:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"shareholding,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4539","NUVL","BK4139"],"gpt_icon":0},{"id":"2553479204","title":"Nuvalent’s Accelerated ALKAZAR Trial Progress and Strong Financials Justify Buy Rating","url":"https://stock-news.laohu8.com/highlight/detail?id=2553479204","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2553479204?lang=en_us&edition=fundamental","pubTime":"2025-07-21 19:26","pubTimestamp":1753097181,"startTime":"0","endTime":"0","summary":"Nuvalent, the Healthcare sector company, was revisited by a Wall Street analyst today. Analyst Charles Zhu from LifeSci Capital maintained a Buy ra...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/ratings/nuvalents-accelerated-alkazar-trial-progress-and-strong-financials-justify-buy-rating-ratings?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/ratings/nuvalents-accelerated-alkazar-trial-progress-and-strong-financials-justify-buy-rating-ratings?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["NUVL","PRGS"],"gpt_icon":0},{"id":"2553447511","title":"Nuvalent doses first patient in Alkazar trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2553447511","media":"TIPRANKS","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2553447511?lang=en_us&edition=fundamental","pubTime":"2025-07-21 18:36","pubTimestamp":1753094166,"startTime":"0","endTime":"0","summary":"Nuvalent (NUVL) announced that the first patient has been dosed in Alkazar, the company’s global Phase 3 randomized, controlled trial evaluating ne...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/nuvalent-doses-first-patient-in-alkazar-trial-thefly?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/nuvalent-doses-first-patient-in-alkazar-trial-thefly?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","BK4539","NUVL"],"gpt_icon":0},{"id":"2553475813","title":"BRIEF-Nuvalent Announces Initiation Of Alkazar Phase 3 Randomized","url":"https://stock-news.laohu8.com/highlight/detail?id=2553475813","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2553475813?lang=en_us&edition=fundamental","pubTime":"2025-07-21 18:31","pubTimestamp":1753093879,"startTime":"0","endTime":"0","summary":"BRIEF-Nuvalent Announces Initiation Of Alkazar Phase 3 RandomizedJuly 21 (Reuters) - Nuvalent Inc NUVL.O:NUVALENT ANNOUNCES INITIATION OF ALKAZAR PHASE 3 RANDOMIZED, CONTROLLED TRIAL EVALUATING NELADA","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250721:nTUA6KT8BY:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4539","BK4139","NUVL"],"gpt_icon":0},{"id":"2553730934","title":"Nuvalent Inc. Launches Phase 3 ALKAZAR Trial Evaluating Neladalkib for ALK-positive NSCLC Patients","url":"https://stock-news.laohu8.com/highlight/detail?id=2553730934","media":"Reuters","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2553730934?lang=en_us&edition=fundamental","pubTime":"2025-07-21 18:30","pubTimestamp":1753093821,"startTime":"0","endTime":"0","summary":"Nuvalent Inc., a clinical-stage biopharmaceutical company, has announced the initiation of the ALKAZAR Phase 3 randomized, controlled trial. This global study is evaluating the efficacy of neladalkib for TKI-nave patients with advanced ALK-positive non-small cell lung cancer , comparing it to ALECENSA , a current front-line standard of care. The trial aims to enroll approximately 450 patients, with a primary focus on progression-free survival based on Blinded Independent Central Review. Secondary endpoints include overall survival and various measures of intracranial response and safety. Results from this trial have not yet been presented and will be awaited in the future.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Nuvalent Inc. pu","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250721:nNDLbcC5dC:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","NUVL","BK4539"],"gpt_icon":0},{"id":"2552431763","title":"James Richard Porter, President and CEO of Nuvalent Inc., Reports Disposal of Common Shares","url":"https://stock-news.laohu8.com/highlight/detail?id=2552431763","media":"Reuters","labels":["shareholding","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2552431763?lang=en_us&edition=fundamental","pubTime":"2025-07-18 04:32","pubTimestamp":1752784320,"startTime":"0","endTime":"0","summary":"James Richard Porter, President and CEO of Nuvalent Inc., reported a disposal of common shares of Nuvalent Inc. The full filing can be accessed through the link below.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Nuvalent Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on July 17, 2025, and is solely responsible for the information contained therein.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250717:nNDL8Mxz5Y:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"shareholding,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4539","NUVL","BK4139"],"gpt_icon":0}],"pageSize":20,"totalPage":4,"pageCount":1,"totalSize":64,"code":"91000000","status":"200"}]}}