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Leap Therapeutics Inc

0.2616

-0.0181-6.47%

Post-market: 0.26990.0083+3.17%19:47 EDT

Volume:1.02M

Turnover:286.19K

Market Cap:10.84M

PE:-0.15

High:0.2914

Open:0.2750

Low:0.2616

Close:0.2797

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Overview Company News Filings

BUZZ-U.S. STOCKS ON THE MOVE-Fiserv, Eli Lilly, Nuclear stocks

BRIEF-Leap Therapeutics Reports Updated Clinical Data From Sirexatamab Colorectal Cancer Study

Leap Therapeutics Inc - to Explore Sale or Partnership for Sirexatamab and Fl-501

THOMSON REUTERS

Leap Therapeutics Inc - Estimates $3.2 Mln Cost for Workforce Reduction

THOMSON REUTERS

Leap Therapeutics Reports Updated Clinical Data From Sirexatamab Colorectal Cancer Study and Announces Exploration of Strategic Alternatives

THOMSON REUTERS

Leap Therapeutics Inc reports results for the quarter ended March 31 - Earnings Summary

BRIEF-Leap Therapeutics Q1 Net Income USD -15.435 Million

BRIEF-Leap Therapeutics - Announces 50% Workforce Reduction In Strategic Restructuring - SEC Filing

Leap Therapeutics Inc - Announces 50% Workforce Reduction in Strategic Restructuring - SEC Filing

THOMSON REUTERS

Leap Therapeutics - Q1 Loss per Share $0.37

THOMSON REUTERS

Leap Therapeutics Reports Q1 2025 Net Loss of $15.4M, Up from $13.8M in Q1 2024, Due to Increased R&D Expenses

Leap Therapeutics Q1 EPS USD -0.37

THOMSON REUTERS

Leap Therapeutics Inc: Has Reduced Its Workforce by Approximately 50%

THOMSON REUTERS

Leap Therapeutics Inc: Strategic Restructuring to Prioritize Clinical Focus on Development of Sirexatamab in Crc

THOMSON REUTERS

Leap Therapeutics Q1 Operating Expenses USD 15.917 Million

THOMSON REUTERS

Leap Therapeutics Inc expected to post a loss of 38 cents a share - Earnings Preview

Leap Therapeutics to Present Preclinical Data of FL-501, a Novel GDF-15 Neutralizing Antibody, at the AACR 2025 Annual Meeting

Leap Therapeutics to Host Virtual KOL Event to Discuss Sirexatamab (DKN-01) in Second-line Patients with Advanced Microsatellite Stable Colorectal Cancer

Penny Stock Leap Therapeutics Unveils Positive Data From Experimental Combo Therapy For Colorectal Cancer

Leap Therapeutics Says New Data Show Sirexatamab Improves Survival in Colorectal Cancer Trial

MT Newswires Live

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The rise in net loss was primarily attributed to increased research and development expenses, which were $12.9 million compared to $11.3 million for the same period in 2024. This increase was mainly due to higher clinical trial costs associated with the expansion of Part B of the DeFianCe study and increased activity related to the end of Part C of the DisTinGuish study. General and administrative expenses decreased to $3.0 million from $3.5 million in the previous year, owing to reductions in professional fees and stock-based compensation expenses. Leap Therapeutics reported cash and cash equivalents totaling $32.7 million as of March 31, 2025. 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Earnings Preview","url":"https://stock-news.laohu8.com/highlight/detail?id=2534345224","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2534345224?lang=en_us&edition=fundamental","pubTime":"2025-05-09 23:28","pubTimestamp":1746804498,"startTime":"0","endTime":"0","summary":"Leap Therapeutics Inc  expected to post a loss of38cents a share - Earnings Preview Leap Therapeutics Inc LPTX.OQ LPTX.O is expected to show no change in quarterly revenue when it reports  results on ","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250509:nL8N3RH2HV:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LPTX"],"gpt_icon":0},{"id":"2530165377","title":"Leap Therapeutics to Present Preclinical Data of FL-501, a Novel GDF-15 Neutralizing Antibody, at the AACR 2025 Annual Meeting","url":"https://stock-news.laohu8.com/highlight/detail?id=2530165377","media":"PR Newswire","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2530165377?lang=en_us&edition=fundamental","pubTime":"2025-04-26 01:00","pubTimestamp":1745600400,"startTime":"0","endTime":"0","summary":"FL-501 fully restored body composition and reversed key indicators of cachexia in preclinical models. Findings confirm GDF-15's role in cachexia and support advancing FL-501 into the clinic. FL-501 is a potential best-in-class monoclonal antibody targeting growth differentiation factor 15 , a cytokine that is implicated in multiple diseases and therapeutic areas, including cancer cachexia.\"Cancer cachexia is a devasting and potentially life-threatening condition characterized by significant weight loss, muscle wasting, fatigue, and severely reduced quality of life. It is a major contributor to cancer-related mortality, and unfortunately there are no effective treatment options available to patients,\" said Jason Baum, PhD, Chief Scientific Officer of Leap. \"These data not only demonstrate that FL-501 is a novel and potential best-in-class anti-GDF-15 antibody, but also capable of fully restoring body composition in preclinical models that is comparable or better than other, clinical-sta","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/leap-therapeutics-present-preclinical-data-170000937.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/leap-therapeutics-present-preclinical-data-170000937.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["FL","LENZ","LPTX"],"gpt_icon":0},{"id":"2527492277","title":"Leap Therapeutics to Host Virtual KOL Event to Discuss Sirexatamab (DKN-01) in Second-line Patients with Advanced Microsatellite Stable Colorectal Cancer","url":"https://stock-news.laohu8.com/highlight/detail?id=2527492277","media":"PR Newswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2527492277?lang=en_us&edition=fundamental","pubTime":"2025-04-15 19:00","pubTimestamp":1744714800,"startTime":"0","endTime":"0","summary":"Virtual KOL Event on Wednesday, April 23, 2025, at 2:30 p.m. ET. CAMBRIDGE, Mass., April 15, 2025 /PRNewswire/ --Leap Therapeutics, Inc. , a biotechnology company focused on developing targeted and immuno-oncology therapeutics, today announced it will host a virtual key opinion leader  event featuring Zev A. Wainberg, MD, Professor of Medicine at University of California, Los Angeles  and co-director of the UCLA GI Oncology Program, on Wednesday, April 23, 2025 at 2:30 p.m. ET. To register, please click here.Dr. Wainberg will connect with Leap's Chief Medical Officer, Cynthia Sirard, MD, to discuss the unmet need and how sirexatamab  may improve upon the current treatment landscape for previously treated patients with advanced microsatellite stable  colorectal cancer .The event will focus on reviewing the positive data from Part B of the Phase 2 DeFianCe study of sirexatamab in second-line patients with advanced MSS CRC. Sirexatamab, Leap's most advanced clinical program, is a humanize","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/leap-therapeutics-host-virtual-kol-110000836.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/leap-therapeutics-host-virtual-kol-110000836.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["IE0031619046.USD","BK4139","KOL","IE00B19Z4B17.USD","AEIS","LPTX","BK4505","BK4157","IE00B7SZL793.SGD","IE00B66KJ199.SGD","HST","BK4585","BK4588","BK4218","BK4563","BK4213","BK4113","CRC","BK4181","LU0456854461.SGD","BK4007","MSS","LENZ","LU0266512127.USD"],"gpt_icon":0},{"id":"2522455332","title":"Penny Stock Leap Therapeutics Unveils Positive Data From Experimental Combo Therapy For Colorectal Cancer","url":"https://stock-news.laohu8.com/highlight/detail?id=2522455332","media":"Benzinga","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2522455332?lang=en_us&edition=fundamental","pubTime":"2025-03-27 01:29","pubTimestamp":1743010151,"startTime":"0","endTime":"0","summary":"Leap Therapeutics, Inc. presented updated preliminary data on Wednesday from Part B of the DeFianCe Phase 2 trial of sirexatamab  in combination with bevacizumab and chemotherapy  compared to bevacizumab and chemotherapy .The trial enrolled patients with advanced microsatellite stable  colorectal cancer  who have received one prior systemic therapy for advanced disease.The updated analysis shared on Wednesday includes the overall response rate , an additional two months of patient follow-up for progression-free survival , and initial overall survival  data.As ofMarch 12, 2025, 34 patients remain on the study drug in the sirexatamab Experimental Arm compared to 24 patients in the Control Arm.In patients with highDKK1levels, the sirexatamab Experimental Arm has a statistically significant 32% higher ORR, 3.5 months longer PFS, and OS compared to the Control Arm:. In patients who had not received prior anti-VEGF therapy, the sirexatamab Experimental Arm has a statistically significant 22%","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/penny-stock-leap-therapeutics-unveils-172911695.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["IE00BMPRXR70.SGD","BK4609","PFS","BK4097","IE00BMPRXQ63.HKD","LENZ","BK4195","LU0348723411.USD","IE00BMPRXN33.USD","BK4113","LPTX","LU0266512127.USD","ONC","CRC","ORR","BK4213","BK4141","BK4585","MSS","OS","BK4563","LU0456854461.SGD","BK4505","BK4211","BK4139","BK4588","BK4543"],"gpt_icon":1},{"id":"2522810870","title":"Leap Therapeutics Says New Data Show Sirexatamab Improves 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