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Ionis Pharmaceuticals

30.71

+0.90003.02%

Post-market: 30.780.0700+0.23%17:58 EDT

Volume:2.41M

Turnover:73.81M

Market Cap:4.88B

PE:-10.12

High:31.82

Open:31.78

Low:29.85

Close:29.81

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Overview Company News Filings

Q1 2025 Ionis Pharmaceuticals Inc Earnings Call

Thomson Reuters StreetEvents

Ionis Pharmaceuticals’ Earnings Call Highlights Growth Amid Challenges

Ionis Pharmaceuticals Is Maintained at Buy by Needham

Ionis Pharmaceuticals: Strong Financial Performance and Strategic Partnerships Justify Buy Rating Despite Adjusted Price Target

Ionis Pharmaceuticals: Strong Performance and Promising Pipeline Justify Buy Rating

Ionis Pharmaceuticals Narrows Q1 Loss, Lifts Revenue Forecast While Drug Sales Surge

BUZZ-Ionis Pharma rises after lifting 2025 revenue forecast

Ionis Pharmaceuticals Inc reports results for the quarter ended March 31 - Earnings Summary

Stock Track | Ionis Pharmaceuticals Soars 6.88% Pre-Market on Strong Q1 Results and Raised 2025 Guidance

Ionis Pharmaceuticals (IONS) Reports Q1 Earnings: What Key Metrics Have to Say

Ionis Pharmaceuticals Q1 Net Loss Narrows as Revenue Increases; 2025 Revenue Guidance Raised

MT Newswires Live

Ionis Pharmaceuticals (IONS) Reports Q1 Loss, Tops Revenue Estimates

Ionis Pharmaceuticals: Q1 Earnings Snapshot

Associated Press Finance

Earnings Flash (IONS) Ionis Pharmaceuticals Posts Q1 EPS Loss $0.93, vs. FactSet Est of $1.10 Loss

MT Newswires Live

Ionis Pharmaceuticals Q1 Adj. EPS $(0.93) Beats $(1.12) Estimate, Sales $132.00M Beat $125.32M Estimate

BRIEF-Ionis Pharmaceuticals Q1 Revenue USD 132 Million Vs. IBES Estimate USD 125.3 Million

Ionis Pharmaceuticals Inc: Increasing 2025 Financial Guidance by More Than 20%

THOMSON REUTERS

Ionis Pharmaceuticals Inc Outlook 2025 REV $725 Mln -$750 Mln

THOMSON REUTERS

Ionis Pharmaceuticals: on Track for Second Independent Launch With Donidalorsen Pdufa August 21, 2025

THOMSON REUTERS

Ionis reports first quarter 2025 financial results

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Brett Monia; Chief Executive Officer, Director; Ionis Pharmaceuticals Inc. Kyle Jenne; Executive Vice President - commercial; Ionis Pharmaceuticals Inc. Elizabeth Hougen; Chief Financial Officer, Executive Vice President - Finance; Ionis Pharmaceuticals Inc. Jonathan Birchall; Chief Commercial Officer; Ionis Pharmaceuticals Inc. Good morning, and welcome to the Ionis first quarter 2025 financial results conference call. As a reminder, this call is being recorded.At this time, I would like to turn the call over to Wade Walke, Senior Vice President of Investor Relations, to lead off the call. Please begin.Thanks, Wade. Good morning, everyone, and thanks for joining us today. Before we discuss our Q1 earnings and recent progress, I want to take a moment to acknowledge the rapidly evolving environment we're living in today.Recent changes at the FDA and the introduction of new tariff policies have introduced a","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/q1-2025-ionis-pharmaceuticals-inc-064351493.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["IONS"],"gpt_icon":0},{"id":"2532101174","title":"Ionis Pharmaceuticals’ Earnings Call Highlights Growth Amid Challenges","url":"https://stock-news.laohu8.com/highlight/detail?id=2532101174","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2532101174?lang=en_us&edition=fundamental","pubTime":"2025-05-01 08:33","pubTimestamp":1746059622,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals Inc. (($IONS)) has held its Q1 earnings call. Read on for the main highlights of the call. Ionis Pharmaceuticals Inc. recentl...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/company-announcements/ionis-pharmaceuticals-earnings-call-highlights-growth-amid-challenges?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/company-announcements/ionis-pharmaceuticals-earnings-call-highlights-growth-amid-challenges?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["IONS"],"gpt_icon":0},{"id":"2532139060","title":"Ionis Pharmaceuticals Is Maintained at Buy by Needham","url":"https://stock-news.laohu8.com/highlight/detail?id=2532139060","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2532139060?lang=en_us&edition=fundamental","pubTime":"2025-05-01 03:40","pubTimestamp":1746042000,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/IONS/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  April 30, 2025 15:40 ET (19:40 GMT)","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"gpt_icon":0},{"id":"2532426060","title":"Ionis Pharmaceuticals: Strong Financial Performance and Strategic Partnerships Justify Buy Rating Despite Adjusted Price Target","url":"https://stock-news.laohu8.com/highlight/detail?id=2532426060","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2532426060?lang=en_us&edition=fundamental","pubTime":"2025-05-01 03:35","pubTimestamp":1746041734,"startTime":"0","endTime":"0","summary":"Needham analyst Joseph Stringer has reiterated their bullish stance on IONS stock, giving a Buy rating today. Joseph Stringer has given his Buy rat...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/ratings/ionis-pharmaceuticals-strong-financial-performance-and-strategic-partnerships-justify-buy-rating-despite-adjusted-price-target?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/ratings/ionis-pharmaceuticals-strong-financial-performance-and-strategic-partnerships-justify-buy-rating-despite-adjusted-price-target?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["IONS"],"gpt_icon":0},{"id":"2532604230","title":"Ionis Pharmaceuticals: Strong Performance and Promising Pipeline Justify Buy Rating","url":"https://stock-news.laohu8.com/highlight/detail?id=2532604230","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2532604230?lang=en_us&edition=fundamental","pubTime":"2025-05-01 03:35","pubTimestamp":1746041721,"startTime":"0","endTime":"0","summary":"Analyst Yaron Werber from TD Cowen reiterated a Buy rating on Ionis Pharmaceuticals (IONS – Research Report) and keeping the price target at $59.00...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/ratings/ionis-pharmaceuticals-strong-performance-and-promising-pipeline-justify-buy-rating?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/ratings/ionis-pharmaceuticals-strong-performance-and-promising-pipeline-justify-buy-rating?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["IONS"],"gpt_icon":0},{"id":"2532061626","title":"Ionis Pharmaceuticals Narrows Q1 Loss, Lifts Revenue Forecast While Drug Sales Surge","url":"https://stock-news.laohu8.com/highlight/detail?id=2532061626","media":"Benzinga","labels":["express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2532061626?lang=en_us&edition=fundamental","pubTime":"2025-05-01 02:05","pubTimestamp":1746036340,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals beat Q1 earnings and revenue estimates, raising its 2025 outlook, and reported strong sales from new and existing drug products.","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.benzinga.com/general/biotech/25/04/45112123/ionis-pharmaceuticals-narrows-q1-loss-lifts-revenue-forecast-while-drug-sales-surge","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"gpt_icon":0},{"id":"2531058971","title":"BUZZ-Ionis Pharma rises after lifting 2025 revenue forecast","url":"https://stock-news.laohu8.com/highlight/detail?id=2531058971","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2531058971?lang=en_us&edition=fundamental","pubTime":"2025-04-30 21:37","pubTimestamp":1746020271,"startTime":"0","endTime":"0","summary":"BUZZ-Ionis Pharma rises after lifting 2025 revenue forecast** Shares of drugmaker Ionis Pharmaceuticals IONS.O rise 6% to $31.65** IONS ups 2025 sales forecast to $725 mln to $750 mln, up from prior forecast of at least $600 mln; analysts were expecting 2025 sales to be $659.7 mln - LSEG** IONS posts Q1 sales of $132 mln vs analysts' est of $125.3 mln - LSEG** IONS reports Q1 loss of 93 cents, compared with a loss of 98 cents a year ago** As of last close, stock down 14.7% YTD","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250430:nL4N3R81NS:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"gpt_icon":0},{"id":"2531205833","title":"Ionis Pharmaceuticals Inc reports results for the quarter ended March 31 - Earnings Summary","url":"https://stock-news.laohu8.com/highlight/detail?id=2531205833","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2531205833?lang=en_us&edition=fundamental","pubTime":"2025-04-30 21:32","pubTimestamp":1746019959,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals Inc reports results for the quarter ended March 31 - Earnings SummaryIonis Pharmaceuticals Inc IONS.OQ reported a quarterly adjusted loss of 93 cents per share for the quarter en","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250430:nL8N3R823Q:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"gpt_icon":0},{"id":"1191402324","title":"Stock Track | Ionis Pharmaceuticals Soars 6.88% Pre-Market on Strong Q1 Results and Raised 2025 Guidance","url":"https://stock-news.laohu8.com/highlight/detail?id=1191402324","media":"Stock Track","labels":["movement"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1191402324?lang=en_us&edition=fundamental","pubTime":"2025-04-30 21:30","pubTimestamp":1746019829,"startTime":"0","endTime":"0","summary":"Shares of Ionis Pharmaceuticals  surged 6.88% in pre-market trading on Wednesday following the company's release of better-than-expected first-quarter 2025 financial results and a significant increase in its full-year revenue guidance.The biotechnology company reported Q1 revenue of $132 million, surpassing the average analyst estimate of $125.3 million. Ionis also posted an adjusted loss per share of $0.93, which was narrower than the expected loss of $1.10 per share. The company's performance ","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":"Stock Track | Ionis Pharmaceuticals Soars 6.88% Pre-Market on Strong Q1 Results and Raised 2025 Guidance","news_tag":"movement","news_rank":0,"length":0,"strategy_id":0,"source":"ai_movement_en","symbols":["IONS"],"gpt_icon":0},{"id":"2531052988","title":"Ionis Pharmaceuticals (IONS) Reports Q1 Earnings: What Key Metrics Have to Say","url":"https://stock-news.laohu8.com/highlight/detail?id=2531052988","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2531052988?lang=en_us&edition=fundamental","pubTime":"2025-04-30 21:30","pubTimestamp":1746019829,"startTime":"0","endTime":"0","summary":"For the quarter ended March 2025, Ionis Pharmaceuticals  reported revenue of $132 million, up 10.9% over the same period last year. EPS came in at -$0.75, compared to -$0.98 in the year-ago quarter.The reported revenue compares to the Zacks Consensus Estimate of $120.16 million, representing a surprise of +9.86%. The company delivered an EPS surprise of +32.43%, with the consensus EPS estimate being -$1.11.While investors closely watch year-over-year changes in headline numbers -- revenue and earnings -- and how they compare to Wall Street expectations to determine their next course of action, some key metrics always provide a better insight into a company's underlying performance.Here is how Ionis Pharmaceuticals performed in the just reported quarter in terms of the metrics most widely monitored and projected by Wall Street analysts:. Revenue- Total commercial revenue: $76 million compared to the $66.61 million average estimate based on eight analysts. The reported number represents ","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/ionis-pharmaceuticals-ions-reports-q1-133029557.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["IONS"],"gpt_icon":0},{"id":"2531343660","title":"Ionis Pharmaceuticals Q1 Net Loss Narrows as Revenue Increases; 2025 Revenue Guidance Raised","url":"https://stock-news.laohu8.com/highlight/detail?id=2531343660","media":"MT Newswires Live","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2531343660?lang=en_us&edition=fundamental","pubTime":"2025-04-30 20:27","pubTimestamp":1746016043,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals  reported a Q1 net loss Wednesday of $0.93 per diluted share, narrowing from a loss of $0.98 a year earlier.Analysts polled by FactSet expected a loss of $1.10.Revenue for the quarter ended March 31 was $132 million, up from $119 million a year earlier.Analysts surveyed by FactSet expected $131.4 million.The California life sciences company said it has lifted its 2025 revenue outlook to between $725 million to $750 million, up from its previous guidance of over $600 million. Analysts polled by FactSet expect $643.0 million.Shares of the company were up more than 3.5% in recent premarket activity.","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["IONS"],"gpt_icon":0},{"id":"2531058249","title":"Ionis Pharmaceuticals (IONS) Reports Q1 Loss, Tops Revenue Estimates","url":"https://stock-news.laohu8.com/highlight/detail?id=2531058249","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2531058249?lang=en_us&edition=fundamental","pubTime":"2025-04-30 20:15","pubTimestamp":1746015308,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals  came out with a quarterly loss of $0.75 per share versus the Zacks Consensus Estimate of a loss of $1.11. This compares to loss of $0.98 per share a year ago. These figures are adjusted for non-recurring items.This quarterly report represents an earnings surprise of 32.43%. A quarter ago, it was expected that this drug discovery and development company would post a loss of $1.12 per share when it actually produced a loss of $0.66, delivering a surprise of 41.07%.Ionis Pharmaceuticals , which belongs to the Zacks Medical - Drugs industry, posted revenues of $132 million for the quarter ended March 2025, surpassing the Zacks Consensus Estimate by 9.86%. This compares to year-ago revenues of $119 million. The company has topped consensus revenue estimates four times over the last four quarters.Ionis Pharmaceuticals shares have lost about 14.7% since the beginning of the year versus the S&P 500's decline of -5.5%.While Ionis Pharmaceuticals has underperformed the mar","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/ionis-pharmaceuticals-ions-reports-q1-121508211.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["IONS"],"gpt_icon":0},{"id":"2531033984","title":"Ionis Pharmaceuticals: Q1 Earnings Snapshot","url":"https://stock-news.laohu8.com/highlight/detail?id=2531033984","media":"Associated Press Finance","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2531033984?lang=en_us&edition=fundamental","pubTime":"2025-04-30 19:13","pubTimestamp":1746011604,"startTime":"0","endTime":"0","summary":"CARLSBAD, Calif.  — CARLSBAD, Calif.  — Ionis Pharmaceuticals Inc.  on Wednesday reported a loss of $147 million in its first quarter.The Carlsbad, California-based company said it had a loss of 93 cents per share. Losses, adjusted for stock option expense, were 75 cents per share.The results beat Wall Street expectations. The average estimate of four analysts surveyed by Zacks Investment Research was for a loss of $1.11 per share.The drug discovery and development company posted revenue of $132 million in the period, also surpassing Street forecasts. Nine analysts surveyed by Zacks expected $120.2 million.Ionis Pharmaceuticals expects full-year revenue in the range of $725 million to $750 million.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/ionis-pharmaceuticals-q1-earnings-snapshot-111324623.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["IONS"],"gpt_icon":0},{"id":"2531033829","title":"Earnings Flash (IONS) Ionis Pharmaceuticals Posts Q1 EPS Loss $0.93, vs. FactSet Est of $1.10 Loss","url":"https://stock-news.laohu8.com/highlight/detail?id=2531033829","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2531033829?lang=en_us&edition=fundamental","pubTime":"2025-04-30 19:07","pubTimestamp":1746011233,"startTime":"0","endTime":"0","summary":"Earnings Flash (IONS) Ionis Pharmaceuticals Posts Q1 EPS Loss $0.93, vs. FactSet Est of $1.10 Loss","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["IONS"],"gpt_icon":0},{"id":"2531038381","title":"Ionis Pharmaceuticals Q1 Adj. 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