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In such a climate, investors often look beyond the larger indices to find opportunities in lesser-known areas like penny stocks. Although the term \"penny stocks\" might seem outdated, these smaller or newer companies can offer significant potential for growth when backed by strong financials and sound fundamentals.Calfrac Well Services, with a market cap of CA$292.88 million, recently reported a net loss for Q4 2024 amid declining sales. The company has seen significant debt reduction over the past five years, yet its current net debt to equity ratio remains high at 42.4%. While short-term and long-term liabilities are covered by assets, interest payments are not well covered by earnings. Recent executive changes could impact future strategy and operations. 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For example, biotech and mining exploration companies often lose money for years before finding success with a new treatment or mineral discovery. But while the successes are well known, investors should not ignore the very many unprofitable companies that simply burn through all their cash and collapse.Given this risk, we thought we'd take a look at whether Eupraxia Pharmaceuticals  shareholders should be worried about its cash burn. For the purposes of this article, cash burn is the annual rate at which an unprofitable company spends cash to fund its growth; its negative free cash flow. 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