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CRISPR Therapeutics AG

52.17

+0.50000.97%

Post-market: 52.170.00000.00%16:58 EDT

Volume:1.84M

Turnover:95.50M

Market Cap:4.51B

PE:-11.55

High:53.08

Open:52.36

Low:51.15

Close:51.67

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Overview Company News Filings

Can CRISPR Build on Casgevy's Success With Its In Vivo Pipeline?

Promising Growth and Diversification Drive Buy Rating for Crispr Therapeutics AG

The 2 Smartest Beaten-Down Biotech Stocks to Buy on the Dip

New Hope for Strokes And Heart Attacks -- Barron's

CRISPR Therapeutics AG's Chief Medical Officer Naimish Patel Reports Disposal of Common Shares

Cathie Wood’s ARK Investment buys 294K shares of Crispr Therapeutics today

Heart Disease Could Be a Goner When These New Drugs Arrive -- Barrons.com

Strokes and Heart Attacks Kill. New Drugs Are Coming to Prevent Them. -- Barrons.com

Mizuho Securities Reaffirms Their Buy Rating on Crispr Therapeutics AG (CRSP)

Crispr Therapeutics Price Target Maintained With a $86.00/Share by JMP Securities

Mizuho Cuts Price Target on CRISPR Therapeutics to $85 From $99, Keeps Outperform Rating

MT Newswires Live

Crispr Therapeutics call volume above normal and directionally bullish

Strategic Growth and De-risking: Gil Blum’s Buy Rating on Crispr Therapeutics AG

Truist Financial Remains a Buy on Crispr Therapeutics AG (CRSP)

Buy Rating for CRISPR Therapeutics: Strategic Collaboration with Sirius Therapeutics to Enhance Pipeline and Capture Anticoagulant Market Share

5 Monster Stocks to Hold for the Next 10 Years

CRISPR Therapeutics Stock Could Double Your Money, According to Wall Street. Is It Time to Buy?

CRISPR, Sirius Collaborate on RNA Therapy Targeting Blood Clot Disorders

MT Newswires Live

Crispr Therapeutics AG Partners with Sirius on siRNA Tech

Crispr Therapeutics And Sirius Therapeutics Announce Multi-Target Collaboration To Develop Novel Sirna Therapies

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A single dose demonstrated dose-dependent decreases in low-density lipoprotein  and triglyceride  levels, with peak reduction of up to 82% in TG and up to 81% in LDL.These results have raised excitement around CTX320, a readout from which is expected later in the second quarter of 2025. CRISPR Therapeutics also intends to advance two additional in vivo programs into the clinic by year-end, further expanding its footprint in this emerging modality.The company is currently lagging behind Intellia TherapeuticsNTLA, which is one of the few companies with multiple clinical-stage in vivo gene editing programs. 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How they could curb bypass surgeries. By Bill Alpert. Forty years after the first statin drug started lowering levels of artery-choking cholesterol, heart attacks and strokes remain the world's biggest killers. This year will see test results on some drugs that cut cholesterol even more.Statins are cheap and effective drugs for reducing blood levels of the \"bad\" cholesterol known as LDL, which gunks up arteries over time. A quarter of Americans have high LDL. But only about half of patients stay on their prescribed statins, and the drugs don't get LDL low enough in some 10% of patients.The cost and hassle has led to sales that are good, but not as great as expected. Regeneron and Sanofi's Praluent sales were $585 million in 2024. For the same year, Amgen's Repatha pulled in $2.2 billion, up 15% year over year. Last year's sales of Leqvio for Novartis were $260 million, up 80%.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","LU2491050154.USD","LU0198837287.USD","LU0882574055.USD","BK4611","AZN","LU2211815571.USD","LU1116320737.USD","LU1127390331.HKD","LU1829250122.USD","LLY","LU2237443895.HKD","LU1934455194.USD","LU0106261372.USD","BK4585","BK4534","LU1974910355.USD","MRK","LU0861579265.USD","IE00BLSP4452.SGD","SG9999015952.SGD","SG9999015341.SGD","BK4516","LU0097036916.USD","LU1232071149.USD","IE00BK4W5L77.USD","AMGN","HOPE","LU0708995401.HKD","LU0058720904.USD","LU2242646821.SGD","LU2471134523.USD","LU0466842654.USD","SG9999002224.SGD","LU0417517546.SGD","SGXZ57979304.SGD","LU0208291251.USD","IE0009355771.USD","LU1116320901.HKD","LU1066051498.USD","IE00BN8TJ469.HKD","IE0004445239.USD","CRSP","LU0320765646.SGD","LU0266013472.USD","LU0320765992.SGD","LU2456880835.USD","LU2471134879.HKD","LU1989772923.USD","LU1291159041.SGD"],"gpt_icon":1},{"id":"2539717208","title":"CRISPR Therapeutics AG's Chief Medical Officer Naimish Patel Reports Disposal of Common Shares","url":"https://stock-news.laohu8.com/highlight/detail?id=2539717208","media":"Reuters","labels":["shareholding","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2539717208?lang=en_us&edition=fundamental","pubTime":"2025-05-31 05:00","pubTimestamp":1748638848,"startTime":"0","endTime":"0","summary":"Naimish Patel, Chief Medical Officer, reported a disposal of common shares of CRISPR Therapeutics AG. The full filing can be accessed through the link below.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. CRISPR Therapeutics AG published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on May 30, 2025, and is solely responsible for the information contained therein.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250530:nNDL7pzfcd:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"CRISPR Therapeutics AG's Chief Medical Officer Naimish Patel Reports Disposal of Common Shares","news_tag":"shareholding,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4611","BK4556","BK4139","LU1861559042.SGD","CRSP","LU1861558580.USD","BK4585","BK4588"],"gpt_icon":0},{"id":"2539290300","title":"Cathie Wood’s ARK Investment buys 294K shares of Crispr Therapeutics today","url":"https://stock-news.laohu8.com/highlight/detail?id=2539290300","media":"TIPRANKS","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2539290300?lang=en_us&edition=fundamental","pubTime":"2025-05-30 08:50","pubTimestamp":1748566214,"startTime":"0","endTime":"0","summary":"20:48 EDT Cathie Wood’s ARK Investment buys 294K shares of Crispr Therapeutics (CRSP) today Published first on TheFly – the ultimate source for rea...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/cathie-woods-ark-investment-buys-294k-shares-of-crispr-therapeutics-today-thefly?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/cathie-woods-ark-investment-buys-294k-shares-of-crispr-therapeutics-today-thefly?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4611","BK4588","LU1861558580.USD","BK4544","BK4539","LU1861559042.SGD","BK4585","BK4007","BK4556","LENZ","CRSP","BK4139","ARKK"],"gpt_icon":0},{"id":"2539940306","title":"Heart Disease Could Be a Goner When These New Drugs Arrive -- Barrons.com","url":"https://stock-news.laohu8.com/highlight/detail?id=2539940306","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2539940306?lang=en_us&edition=fundamental","pubTime":"2025-05-29 02:06","pubTimestamp":1748455560,"startTime":"0","endTime":"0","summary":"Forty years after the first statin drug started lowering levels of artery-choking cholesterol, heart attacks and strokes remain the world's biggest killers. This year will see test results on some drugs that cut cholesterol even more.Statins are cheap and effective drugs for reducing blood levels of the \"bad\" cholesterol known as LDL, which gunks up arteries over time. A quarter of Americans have high LDL. But only about half of patients stay on their prescribed statins, and the drugs don't get LDL low enough in some 10% of patients.\"Even with everything that we've done in the field, there is actually a fair amount of new things in the pipeline,\" said researcher Steve Nissen, a cardiologist at the Cleveland Clinic who conducts clinical trials on many of the new drugs.To address these drugs' cost and convenience issues, Merck is testing a pill treatment that it code-named MK-0616. The company is b","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU2491050071.SGD","LU1941712264.USD","LU2602419157.SGD","BK4566","LU1814569148.SGD","BK4559","IE00B2B36J28.USD","BK4139","LU0203202063.USD","LU2468319806.SGD","IE00B1BXHZ80.USD","SG9999018857.SGD","LU0096364046.USD","SGXZ31699556.SGD","LU0786609619.USD","BK4556","LU0689472784.USD","LU0708995401.HKD","LU1720051017.SGD","IE0004445239.USD","LU1861558580.USD","LU2063271972.USD","SG9999001176.SGD","SG9999014906.USD","LU1934455277.USD","LU2237443622.USD","LU2237443895.HKD","LU1623119135.USD","LU1804176565.USD","LU0320765992.SGD","LU1934455863.HKD","LU0466842654.USD","LU1989771016.USD","LU0354030438.USD","LU0079474960.USD","SG9999014880.SGD","LU1066053197.SGD","MRK","CRSP","LU1551013342.USD","LU2471134523.USD","AZN","BK4611","LU1035775433.USD","IE00BSNM7G36.USD","LLY","LU0234572021.USD","LU1988902786.USD","LU2211815571.USD","AMGN"],"gpt_icon":1},{"id":"2537790257","title":"Strokes and Heart Attacks Kill. New Drugs Are Coming to Prevent Them. -- Barrons.com","url":"https://stock-news.laohu8.com/highlight/detail?id=2537790257","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2537790257?lang=en_us&edition=fundamental","pubTime":"2025-05-23 15:00","pubTimestamp":1747983600,"startTime":"0","endTime":"0","summary":"Forty years after the first statin drug started lowering levels of artery-choking cholesterol, heart attacks and strokes remain the world's biggest killers. This year, we'll see test results on some drugs that cut cholesterol even more.Statins are cheap and effective drugs for reducing blood levels of the \"bad\" cholesterol known as LDL, which gunks up arteries over time. A quarter of Americans have high LDL. But only about half of patients stay on their prescribed statins, and the drugs don't get LDL low enough in some 10% of patients.A pack of new cardiovascular drugs are being tried as pills, biweekly or semiannual shots, and even as once-for-a-lifetime infusions. And their benefits all seem additive to those of statins and each other. Successful trial results in the next few years could save thousands of lives and generate billions in new annual revenue for drugmakers.Merck aims for a bigger market than just high-LDL families, so a third Phase 3 for MK-0616 will use the gold-standar","market":"other","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SG9999018857.SGD","LU0861579265.USD","LU2471134796.USD","LU2602419157.SGD","LU1934455277.USD","SG9999018865.SGD","LU2237443895.HKD","LU0289739699.SGD","LU1066051811.HKD","SG9999001440.SGD","LU0965508806.USD","IE00B1BXHZ80.USD","LU0238689110.USD","IE00BFTCPJ56.SGD","LU1623119135.USD","LU2471134952.CNY","LU2746668461.USD","IE00BN8TJ469.HKD","LU2362540622.SGD","AZN","LU0417517546.SGD","MRK","LU1232071149.USD","IE000M9KFDE8.USD","LU2362541273.HKD","LU2750360641.GBP","CRSP","LU1037948541.HKD","LU1551013342.USD","LU2265009873.SGD","REGN","LU1066053197.SGD","LU1917777945.USD","LU1934455863.HKD","SG9999014575.USD","LU2237443622.USD","LU2324357040.USD","SG9999015978.USD","LU0203201768.USD","LU2361044865.SGD","LU2237443978.SGD","LU1066051498.USD","LU1291159041.SGD","LLY","IE0004445239.USD","LU2237443382.USD","LU0320765489.SGD","LU0823416689.USD","LU0198837287.USD","LU0320765992.SGD"],"gpt_icon":1},{"id":"2537942424","title":"Mizuho Securities Reaffirms Their Buy Rating on Crispr Therapeutics AG (CRSP)","url":"https://stock-news.laohu8.com/highlight/detail?id=2537942424","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2537942424?lang=en_us&edition=fundamental","pubTime":"2025-05-22 21:55","pubTimestamp":1747922115,"startTime":"0","endTime":"0","summary":"In a report released on May 20, Salim Syed from Mizuho Securities maintained a Buy rating on Crispr Therapeutics AG (CRSP – Research Report), with 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Cuts Price Target on CRISPR Therapeutics to $85 From $99, Keeps Outperform Rating","url":"https://stock-news.laohu8.com/highlight/detail?id=2537198786","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2537198786?lang=en_us&edition=fundamental","pubTime":"2025-05-21 19:20","pubTimestamp":1747826456,"startTime":"0","endTime":"0","summary":"CRISPR Therapeutics (CRSP) has an average rating of overweight and mean price target of $77.56, according to analysts polled by FactSet.(MT Newswires covers equity, commodity and economic research 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implied vol increasing almost 2 points to 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Gil Blu...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/ratings/strategic-growth-and-de-risking-gil-blums-buy-rating-on-crispr-therapeutics-ag?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/ratings/strategic-growth-and-de-risking-gil-blums-buy-rating-on-crispr-therapeutics-ag?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["LENZ","CRSP","AG"],"gpt_icon":0},{"id":"2536561430","title":"Truist Financial Remains a Buy on Crispr Therapeutics AG (CRSP)","url":"https://stock-news.laohu8.com/highlight/detail?id=2536561430","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2536561430?lang=en_us&edition=fundamental","pubTime":"2025-05-20 19:35","pubTimestamp":1747740941,"startTime":"0","endTime":"0","summary":"Truist Financial analyst Joon Lee maintained a Buy rating on Crispr Therapeutics AG (CRSP – Research Report) today. The company’s shares closed yes...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/truist-financial-remains-a-buy-on-crispr-therapeutics-ag-crsp-2?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/truist-financial-remains-a-buy-on-crispr-therapeutics-ag-crsp-2?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4210","CRSP","BK4139","BK4556","BK4588","BK4585","AG","LU1861558580.USD","LU1861559042.SGD","BK4611"],"gpt_icon":0},{"id":"2536948896","title":"Buy Rating for CRISPR Therapeutics: Strategic Collaboration with Sirius Therapeutics to Enhance Pipeline and Capture Anticoagulant Market Share","url":"https://stock-news.laohu8.com/highlight/detail?id=2536948896","media":"TIPRANKS","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2536948896?lang=en_us&edition=fundamental","pubTime":"2025-05-20 16:55","pubTimestamp":1747731314,"startTime":"0","endTime":"0","summary":"William Blair analyst Sami Corwin has maintained their bullish stance on CRSP stock, giving a Buy rating yesterday. Sami Corwin has given his Buy r...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/ratings/buy-rating-for-crispr-therapeutics-strategic-collaboration-with-sirius-therapeutics-to-enhance-pipeline-and-capture-anticoagulant-market-share?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/ratings/buy-rating-for-crispr-therapeutics-strategic-collaboration-with-sirius-therapeutics-to-enhance-pipeline-and-capture-anticoagulant-market-share?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"corporation","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["CRSP","LENZ"],"gpt_icon":0},{"id":"2536699139","title":"5 Monster Stocks to Hold for the Next 10 Years","url":"https://stock-news.laohu8.com/highlight/detail?id=2536699139","media":"Motley Fool","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2536699139?lang=en_us&edition=fundamental","pubTime":"2025-05-20 16:30","pubTimestamp":1747729800,"startTime":"0","endTime":"0","summary":"These companies are just starting to realize the potential in up-and-coming fields, like AI and gene editing.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.fool.com/investing/2025/05/20/5-monster-stocks-to-hold-for-the-next-10-years/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"fool_stock","symbols":["LU0957808578.USD","LU1267930573.SGD","NVD3.UK","NVDS","IE00BSNM7G36.USD","NVIW.SI","LU2357125470.USD","NVDS.UK","LU1066053197.SGD","LU2430703251.USD","LU0985489474.SGD","LU0069063385.USD","LU2452424414.USD","LU0081259029.USD","LU2456880835.USD","LU1548497426.USD","LU2458330169.SGD","BK4550","LU0130518102.USD","LU1084165304.USD","LU1815336760.USD","LU0433182093.SGD","2NVD.UK","USJW.SI","BK4527","LU2461242641.AUD","NVDU","NVD2.UK","LU1852331112.SGD","NVD","NVDD","NVDY","LU2552382132.HKD","LU2125909759.SGD","BK4567","SNVD.UK","3NVD.UK","NVDA","CRSP","IE00BMPRXR70.SGD","IE00BFSS8Q28.SGD","LU0823434740.USD","BK4077","LU0444971666.USD","LU1267930227.SGD","LU0345768740.USD"],"gpt_icon":1},{"id":"2536369562","title":"CRISPR Therapeutics Stock Could Double Your Money, According to Wall Street. Is It Time to Buy?","url":"https://stock-news.laohu8.com/highlight/detail?id=2536369562","media":"Motley Fool","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2536369562?lang=en_us&edition=fundamental","pubTime":"2025-05-20 15:43","pubTimestamp":1747726980,"startTime":"0","endTime":"0","summary":"CRISPR Therapeutics stock is down more than 80% from the peak it reached in 2021.The first drug from CRISPR Therapeutics launched early last year, but annualized sales are still less than $60 million.CRISPR Therapeutics recently reported promising early-stage clinical trial results for a cholesterol-reducing treatment.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.fool.com/investing/2025/05/20/crispr-therapeutics-stock-could-double-your-money/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"fool_stock","symbols":["SG9999013999.USD","BK4539","IE0009355771.USD","IE0002141913.USD","BK4585","IE00B19Z9P08.USD","BK4532","LU1035775433.USD","LU2462157665.USD","IE00BJT1NW94.SGD","BK4588","LU0889565916.HKD","LU1093756325.SGD","IE00B894F039.SGD","LU0823416689.USD","IE00BZ9MQY76.HKD","LU0234570918.USD","IE00B4R5TH58.HKD","BK4556","LENZ","LU2236285917.USD","LU2362540622.SGD","BK4023","LU2362541273.HKD","CRSP","LU1585245621.USD","LU0058720904.USD","IE00B19Z3B42.SGD","SG9999001176.SGD","LU1861558580.USD","IE00BJJMRZ35.SGD","SGXZ57979304.SGD","BK4086","LU2237438978.USD","IE00B2B36J28.USD","SSD","LU0109394709.USD","LU0566484027.USD","LU0079474960.USD","LU1069344957.HKD","BK4611","LU2362541513.USD","LU1430594728.SGD","VRTX","BK4007","VERX","IE0002270589.USD","LU0061475181.USD","SG9999001176.USD","BK4139"],"gpt_icon":0},{"id":"2536165830","title":"CRISPR, Sirius Collaborate on RNA Therapy Targeting Blood Clot Disorders","url":"https://stock-news.laohu8.com/highlight/detail?id=2536165830","media":"MT Newswires Live","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2536165830?lang=en_us&edition=fundamental","pubTime":"2025-05-20 05:19","pubTimestamp":1747689549,"startTime":"0","endTime":"0","summary":"CRISPR Therapeutics  and Sirius Therapeutics have entered a collaboration to develop small interfering RNA-based treatments, starting with SRSD107, a Factor XI-targeting therapy for thromboembolic conditions, the companies said late Monday.Under the agreement, CRISPR will provide $25 million in cash and $70 million in equity to Sirius upfront. The companies will jointly develop SRSD107 under a 50-50 cost and profit-sharing model, with CRISPR leading US commercialization and Sirius overseeing Greater China.CRISPR also holds exclusive rights to license up to two additional siRNA programs, according to a joint statement.SRSD107 is a long-acting siRNA that selectively inhibits Factor XI, a driver of pathological clot formation, with limited effect on normal clotting. Phase 1 trials showed the therapy was safe, well-tolerated, and delivered sustained reductions in FXI levels for up to six months after a single dose, suggesting potential as a twice-yearly treatment.","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"corporation","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["CRSP","LU1861558580.USD","BK4585","BK4611","BK4588","BK4556","BK4505","BK4139","LU1861559042.SGD","RNA"],"gpt_icon":0},{"id":"2536658677","title":"Crispr Therapeutics AG Partners with Sirius on siRNA Tech","url":"https://stock-news.laohu8.com/highlight/detail?id=2536658677","media":"TIPRANKS","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2536658677?lang=en_us&edition=fundamental","pubTime":"2025-05-20 05:07","pubTimestamp":1747688837,"startTime":"0","endTime":"0","summary":"Crispr Therapeutics AG ( ($CRSP) ) has issued an update. On May 19, 2025, CRISPR Therapeutics AG announced a collaboration agreement with Sirius 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