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Charles River Laboratories

155.46

+2.801.83%

Post-market: 155.460.00000.00%19:47 EDT

Volume:987.64K

Turnover:153.31M

Market Cap:7.65B

PE:-53.38

High:158.76

Open:155.62

Low:153.05

Close:152.66

52wk High:228.88

52wk Low:91.86

Shares:49.22M

Float Shares:48.62M

Volume Ratio:1.00

T/O Rate:2.03%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-2.9122

EPS(LYR):-2.9122

ROE:-4.23%

ROA:4.24%

PB:2.42

PE(LYR):-53.38

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Overview Company News Filings

Charles River Laboratories International Inc. Stock Outperforms Competitors On Strong Trading Day

Press Release: Pharming Group reports fourth quarter and full year 2025 financial results, delivering strong revenue growth and profitability with positive cash flow

Regenxbio Reports Duchenne Gene Therapy Progress As Stock Slides On Mixed Signals

Benzinga_recent_news

Seikagaku Resubmits U.S. Application for Disc Herniation Drug After Addressing FDA Concerns

MT Newswires Live

Charles River Laboratories International Inc. Stock Underperforms Monday When Compared To Competitors Despite Daily Gains

Baird Adjusts Price Target on Charles River Laboratories International to $197 From $193

MT Newswires Live

Charles River Laboratories International Inc. Stock Underperforms Friday When Compared To Competitors

Charles River Laboratories International Inc. Stock Outperforms Competitors On Strong Trading Day

Charles River (CRL) Trims 2026 Outlook After Divestitures and Leadership Changes Is The Strategy Working?

Simply Wall St.

Charles River Laboratories International Inc. Stock Underperforms Tuesday When Compared To Competitors

Charles River Laboratories to Present at TD Cowen and Barclays Investor Conferences

Charles River Laboratories International Inc. Stock Outperforms Competitors On Strong Trading Day

Press Release: Disc Medicine Reports Fourth Quarter and Full Year 2025 Financial Results and Provides Business Update

Barclays Remains a Buy on Charles River Labs (CRL)

Charles River Labs Is Maintained at Neutral by UBS

UBS Adjusts Price Target on Charles River Laboratories International to $175 From $170, Maintains Neutral Rating

MT Newswires Live

Charles River raises annual profit view as it sells underperforming assets

Iqvia to acquire certain discovery services assets from Charles River

GUIDANCE: (CRL) Charles River Laboratories Expects 2026 Adjusted EPS Including Impact of Planned Divestitures Range $10.80 - $11.30

MT Newswires Live

Charles River signs deals to sell European Discovery Services assets and CDMO and Cell Solutions businesses

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Stock Outperforms Competitors On Strong Trading Day","url":"https://stock-news.laohu8.com/highlight/detail?id=2619439511","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2619439511?lang=en_us&edition=fundamental","pubTime":"2026-03-14 05:18","pubTimestamp":1773436680,"startTime":"0","endTime":"0","summary":"This article was automatically generated by MarketWatch using technology from Automated Insights.Shares of Charles River Laboratories International Inc.  advanced 1.83% to $155.46 Friday, on what proved to be an all-around dismal trading session for the stock market, with the S&P 500 Index  falling 0.61% to 6,632.19 and Dow Jones Industrial Average  falling 0.26% to 46,558.47.Charles River Laboratories International Inc. closed 32.08% short of its 52-week high of $228.88, which the company reached on January 13th.The stock outperformed some of its competitors Friday, as Labcorp Holdings Inc.  rose 0.34% to $263.80, Alnylam Pharmaceuticals Inc.  fell 1.20% to $313.41, and Bio-Techne Corp.  fell 1.20% to $50.85.Trading volume  eclipsed its 50-day average volume of 986,824.Data source: Dow Jones Market Data, FactSet. Data compiled March 13, 2026.This content was created by MarketWatch, which is operated by Dow Jones & Co. MarketWatch is published independently from Dow Jones Newswires and","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["CRL"],"gpt_icon":0},{"id":"2618907060","title":"Press Release: Pharming Group reports fourth quarter and full year 2025 financial results, delivering strong revenue growth and profitability with positive cash flow","url":"https://stock-news.laohu8.com/highlight/detail?id=2618907060","media":"Dow Jones","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618907060?lang=en_us&edition=fundamental","pubTime":"2026-03-12 14:00","pubTimestamp":1773295200,"startTime":"0","endTime":"0","summary":"-- Full year 2025 total revenues increased by 27% to US$376.1 million,driven by continued growth of RUCONEST and rising demand for Joenja. fourth quarter revenue increased by 9% to US$86.7 million. -- Joenja revenue increased by 29% to US$58.2 million and fourth quarter. growth), driven by significant and accelerating growth for Joenja and. \"2025 was a defining year for Pharming and reflects the focus and discipline our teams have brought to executing our strategy. We outperformed revenue guidance and delivered strong financial performance, with total revenues up 27%, driven by continued RUCONEST growth and rising demand for Joenja .Building on this momentum, we plan to further enhance capital allocation to drive growth. We expect 2026 total revenues in the range of US$405 million to US$425 million, representing 8% to 13% growth, driven by both Joenja and RUCONEST.","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["EEA","BK4232","BK4218","BK4530","BK4087","PK","LU0390134368.USD","LU0128526141.USD","IE00BFMHRM44.USD","R","BK4588","BK4121","BK4081","BK4022","BK4215","MAA","EMA","LU0757428866.USD","CRL","LU0029874061.USD","BK4139","CHMP","LU1815336091.USD","BK4585","BK4181","PHAR"],"gpt_icon":0},{"id":"2618942920","title":"Regenxbio Reports Duchenne Gene Therapy Progress As Stock Slides On Mixed Signals","url":"https://stock-news.laohu8.com/highlight/detail?id=2618942920","media":"Benzinga_recent_news","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618942920?lang=en_us&edition=fundamental","pubTime":"2026-03-12 02:19","pubTimestamp":1773253140,"startTime":"0","endTime":"0","summary":"Regenxbio releases new Duchenne trial data showing improved motor function and stable heart measures in early-stage patients.","market":"sh","thumbnail":"https://cdn.benzinga.com/files/images/story/2026/03/11/Gene-therapy-research.jpeg?optimize=medium&dpr=2&auto=webp&width=240","type":0,"news_type":0,"thumbnails":["https://cdn.benzinga.com/files/images/story/2026/03/11/Gene-therapy-research.jpeg?optimize=medium&dpr=2&auto=webp&width=240"],"rights":{"source":"benzinga_recent_news","url":"https://www.benzinga.com/markets/biotech/26/03/51196009/regenxbio-reports-duchenne-gene-therapy-progress-as-stock-slides-on-mixed-signals","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.benzinga.com/markets/biotech/26/03/51196009/regenxbio-reports-duchenne-gene-therapy-progress-as-stock-slides-on-mixed-signals","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"benzinga_recent_news","symbols":["BK4530","LU0757428866.USD","RGNX","BK4585","LU0390134368.USD","PRGS","BK4121","LU0128526141.USD","BK4563","LU2065732104.USD","LU1815336091.USD","CRL","BK4505","BK4097","BK4217","LU0029874061.USD","SMA","BK4139","IE00BFMHRM44.USD","BK4588"],"gpt_icon":0},{"id":"2618939123","title":"Seikagaku Resubmits U.S. Application for Disc Herniation Drug After Addressing FDA Concerns","url":"https://stock-news.laohu8.com/highlight/detail?id=2618939123","media":"MT Newswires Live","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618939123?lang=en_us&edition=fundamental","pubTime":"2026-03-10 18:23","pubTimestamp":1773138223,"startTime":"0","endTime":"0","summary":"Seikagaku  resubmitted its biologics license application to the U.S. FDA for SI-6603 , a potential treatment for lumbar disc herniation, according to its Tokyo bourse filing on Tuesday.The resubmission follows a complete response letter  received in March 2025, which raised no concerns about the drug's clinical efficacy or safety but cited issues related to the manufacturing facility and quality control.The CRL is an FDA notification that an application will not be approved in its current state after review.Seikagaku has since addressed these observations and is working with licensing partner Ferring Pharmaceuticals to pursue approval and offer a new non-surgical option for reducing leg pain associated with the condition.","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["LU0128526141.USD","BK7095","CRL.AU","IE00BFMHRM44.USD","LU0029874061.USD","BK4588","BK4121","BK4530","LU1815336091.USD","LABU","BK4585","LU0757428866.USD","LU0390134368.USD","CRL"],"gpt_icon":0},{"id":"2618985677","title":"Charles River Laboratories International Inc. Stock Underperforms Monday When Compared To Competitors Despite Daily Gains","url":"https://stock-news.laohu8.com/highlight/detail?id=2618985677","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618985677?lang=en_us&edition=fundamental","pubTime":"2026-03-10 05:17","pubTimestamp":1773091020,"startTime":"0","endTime":"0","summary":"This article was automatically generated by MarketWatch using technology from Automated Insights.Shares of Charles River Laboratories International Inc.  rallied 1.45% to $176.99 Monday, on what proved to be an all-around great trading session for the stock market, with the S&P 500 Index  rising 0.83% to 6,795.99 and the Dow Jones Industrial Average  rising 0.50% to 47,740.80.Charles River Laboratories International Inc. closed 22.67% short of its 52-week high of $228.88, which the company reached on January 13th.The stock demonstrated a mixed performance when compared to some of its competitors Monday, as Labcorp Holdings Inc.  rose 1.46% to $273.61, Alnylam Pharmaceuticals Inc.  rose 0.91% to $323.59, and Bio-Techne Corp.  rose 1.82% to $54.87.Trading volume  eclipsed its 50-day average volume of 939,356.Data source: Dow Jones Market Data, FactSet. Data compiled March 9, 2026.This content was created by MarketWatch, which is operated by Dow Jones & Co. MarketWatch is published indepe","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["CRL"],"gpt_icon":0},{"id":"2618862651","title":"Baird Adjusts Price Target on Charles River Laboratories International to $197 From $193","url":"https://stock-news.laohu8.com/highlight/detail?id=2618862651","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618862651?lang=en_us&edition=fundamental","pubTime":"2026-03-09 20:36","pubTimestamp":1773059802,"startTime":"0","endTime":"0","summary":"Charles River Laboratories International (CRL) has an average rating of overweight and mean price target of $200.50, according to analysts polled by FactSet.(MT Newswires covers equity, commodity and ","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["CRL"],"gpt_icon":0},{"id":"2617565306","title":"Charles River Laboratories International Inc. Stock Underperforms Friday When Compared To Competitors","url":"https://stock-news.laohu8.com/highlight/detail?id=2617565306","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2617565306?lang=en_us&edition=fundamental","pubTime":"2026-03-07 06:18","pubTimestamp":1772835480,"startTime":"0","endTime":"0","summary":"This article was automatically generated by MarketWatch using technology from Automated Insights.Shares of Charles River Laboratories International Inc.  slipped 3.78% to $174.46 Friday, on what proved to be an all-around dismal trading session for the stock market, with the S&P 500 Index  falling 1.33% to 6,740.02 and Dow Jones Industrial Average  falling 0.95% to 47,501.55.The stock's fall snapped a two-day winning streak.Charles River Laboratories International Inc. closed 23.78% below its 52-week high of $228.88, which the company reached on January 13th.The stock underperformed when compared to some of its competitors Friday, as Labcorp Holdings Inc.  fell 2.27% to $269.67, Alnylam Pharmaceuticals Inc.  rose 0.05% to $320.66, and Bio-Techne Corp.  fell 3.58% to $53.89.Trading volume  eclipsed its 50-day average volume of 930,413.Data source: Dow Jones Market Data, FactSet. Data compiled March 6, 2026.This content was created by MarketWatch, which is operated by Dow Jones & Co. Mar","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["CRL"],"gpt_icon":0},{"id":"2617344562","title":"Charles River Laboratories International Inc. Stock Outperforms Competitors On Strong Trading Day","url":"https://stock-news.laohu8.com/highlight/detail?id=2617344562","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2617344562?lang=en_us&edition=fundamental","pubTime":"2026-03-05 06:21","pubTimestamp":1772662860,"startTime":"0","endTime":"0","summary":"This article was automatically generated by MarketWatch using technology from Automated Insights.Shares of Charles River Laboratories International Inc.  rose 2.21% to $179.58 Wednesday, on what proved to be an all-around great trading session for the stock market, with the S&P 500 Index  rising 0.78% to 6,869.50 and the Dow Jones Industrial Average  rising 0.49% to 48,739.41.Charles River Laboratories International Inc. closed 21.54% short of its 52-week high of $228.88, which the company reached on January 13th.The stock demonstrated a mixed performance when compared to some of its competitors Wednesday, as Labcorp Holdings Inc.  fell 0.76% to $280.85, Alnylam Pharmaceuticals Inc.  rose 2.71% to $327.30, and Bio-Techne Corp.  rose 1.51% to $57.85.Trading volume  remained 186,749 below its 50-day average volume of 929,561.Data source: Dow Jones Market Data, FactSet. Data compiled March 4, 2026.This content was created by MarketWatch, which is operated by Dow Jones & Co. MarketWatch is","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["CRL"],"gpt_icon":0},{"id":"2616559908","title":"Charles River (CRL) Trims 2026 Outlook After Divestitures and Leadership Changes Is The Strategy Working?","url":"https://stock-news.laohu8.com/highlight/detail?id=2616559908","media":"Simply Wall St.","labels":["executive"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2616559908?lang=en_us&edition=fundamental","pubTime":"2026-03-04 22:26","pubTimestamp":1772634406,"startTime":"0","endTime":"0","summary":"In February 2026, Charles River Laboratories International reported fourth-quarter and full-year 2025 results showing slightly lower revenue of US$994.23 million for the quarter and US$4.02 billion for the year, a net loss driven in part by US$210.97 million of intangible asset impairments and US$165 million of goodwill impairments, and issued 2026 guidance calling for at least flat to 1.5% reported revenue growth and GAAP EPS of US$6.30 to US$6.80. \nSoon after, the company adjusted its 2026...","market":"nz","thumbnail":"https://images.simplywall.st/asset/industry/9551728-choice2-main-header/1585186774276","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/9551728-choice2-main-header/1585186774276"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nyse-crl/charles-river-laboratories-international/news/charles-river-crl-trims-2026-outlook-after-divestitures-and","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nyse-crl/charles-river-laboratories-international/news/charles-river-crl-trims-2026-outlook-after-divestitures-and","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"executive","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["BK4585","LU0390134368.USD","LU0757428866.USD","CRL","CRL.AU","LU0029874061.USD","BK4530","IE00BFMHRM44.USD","LU0128526141.USD","BK4121","BK7095","BK4588","LU1815336091.USD"],"gpt_icon":0},{"id":"2616377924","title":"Charles River Laboratories International Inc. Stock Underperforms Tuesday When Compared To Competitors","url":"https://stock-news.laohu8.com/highlight/detail?id=2616377924","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2616377924?lang=en_us&edition=fundamental","pubTime":"2026-03-04 06:18","pubTimestamp":1772576280,"startTime":"0","endTime":"0","summary":"This article was automatically generated by MarketWatch using technology from Automated Insights.Shares of Charles River Laboratories International Inc.  shed 1.63% to $175.69 Tuesday, on what proved to be an all-around grim trading session for the stock market, with the S&P 500 Index  falling 0.94% to 6,816.63 and Dow Jones Industrial Average  falling 0.83% to 48,501.27.The stock's fall snapped a five-day winning streak.Charles River Laboratories International Inc. closed 23.24% below its 52-week high of $228.88, which the company achieved on January 13th.The stock demonstrated a mixed performance when compared to some of its competitors Tuesday, as Labcorp Holdings Inc.  fell 1.21% to $282.99, Alnylam Pharmaceuticals Inc.  fell 1.97% to $318.65, and Bio-Techne Corp.  fell 1.44% to $56.99.Trading volume  remained 135,450 below its 50-day average volume of 925,493.Data source: Dow Jones Market Data, FactSet. Data compiled March 3, 2026.This content was created by MarketWatch, which is ","market":"other","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["CRL"],"gpt_icon":0},{"id":"2616033247","title":"Charles River Laboratories to Present at TD Cowen and Barclays Investor Conferences","url":"https://stock-news.laohu8.com/highlight/detail?id=2616033247","media":"Reuters","labels":["conferences"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2616033247?lang=en_us&edition=fundamental","pubTime":"2026-03-02 21:00","pubTimestamp":1772456445,"startTime":"0","endTime":"0","summary":"Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Charles River Laboratories International Inc. published the original content used to generate this news brief via Business Wire  on March 02, 2026, and is solely responsible for the information contained therein.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260302:nNDL8NdmFP:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"conferences","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4588","LU0757428866.USD","IE00BFMHRM44.USD","LU0128526141.USD","LU0390134368.USD","BK4530","LU1815336091.USD","BK4121","BK4585","LU0029874061.USD","CRL"],"gpt_icon":0},{"id":"2614898899","title":"Charles River Laboratories International Inc. Stock Outperforms Competitors On Strong Trading Day","url":"https://stock-news.laohu8.com/highlight/detail?id=2614898899","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2614898899?lang=en_us&edition=fundamental","pubTime":"2026-02-28 06:20","pubTimestamp":1772230800,"startTime":"0","endTime":"0","summary":"This article was automatically generated by MarketWatch using technology from Automated Insights.Shares of Charles River Laboratories International Inc.  rose 1.73% to $178.49 Friday, on what proved to be an all-around rough trading session for the stock market, with the S&P 500 Index  falling 0.43% to 6,878.88 and Dow Jones Industrial Average  falling 1.05% to 48,977.92.This was the stock's fourth consecutive day of gains.Charles River Laboratories International Inc. closed 22.02% below its 52-week high of $228.88, which the company achieved on January 13th.The stock demonstrated a mixed performance when compared to some of its competitors Friday, as Labcorp Holdings Inc.  rose 0.77% to $289.12, Alnylam Pharmaceuticals Inc.  rose 0.51% to $332.92, and Bio-Techne Corp.  rose 1.86% to $59.00.Trading volume  eclipsed its 50-day average volume of 916,133.Data source: Dow Jones Market Data, FactSet. Data compiled February 27, 2026.This content was created by MarketWatch, which is operated ","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["CRL"],"gpt_icon":0},{"id":"2614042239","title":"Press Release: Disc Medicine Reports Fourth Quarter and Full Year 2025 Financial Results and Provides Business Update","url":"https://stock-news.laohu8.com/highlight/detail?id=2614042239","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2614042239?lang=en_us&edition=fundamental","pubTime":"2026-02-26 21:30","pubTimestamp":1772112600,"startTime":"0","endTime":"0","summary":"-- Pursuing a traditional approval path for bitopertin in erythropoietic. protoporphyria ; Phase 3 APOLLO study is expected to complete. enrollment in March 2026 with topline data expected in Q4 2026. -- Initial data from Phase 2 study of DISC-0974 in patients with anemia of. myelofibrosis  presented at the American Society of Hematology . conference demonstrating meaningful overall anemia responses across all. patient subgroups, regardless of baseline transfusion status or. -- Progressing ongoing Phase 2 study of DISC-3405 in polycythemia vera . and initiated a Phase 1b study of DISC-3405 in sickle cell disease . in Q4 2025, with data from both studies expected in 2H 2026. cash, cash equivalents, and marketable securities, providing runway into. Administration  in February 2026 related to sufficiency of evidence. adolescents with EPP, with topline data expected Q4 2026. anemia of myelofibrosis  presented at ASH Annual Meeting i","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0390134368.USD","BK4582","LU0029874061.USD","CRL","IE00BFMHRM44.USD","LU2463526074.USD","IBD","BK4530","EPP","LU0128526141.USD","BK4121","BK4585","IRON","SCD","BK4109","LU1815336091.USD","LU0757428866.USD","LU0053671581.USD","BK4588","BK4139","ASH"],"gpt_icon":0},{"id":"2614014260","title":"Barclays Remains a Buy on Charles River Labs (CRL)","url":"https://stock-news.laohu8.com/highlight/detail?id=2614014260","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2614014260?lang=en_us&edition=fundamental","pubTime":"2026-02-26 18:06","pubTimestamp":1772100398,"startTime":"0","endTime":"0","summary":"In a report released today, Luke Sergott from Barclays maintained a Buy rating on Charles River Labs, with a price target of $200.00. According to ...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/barclays-remains-a-buy-on-charles-river-labs-crl-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/barclays-remains-a-buy-on-charles-river-labs-crl-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["LU0029874061.USD","LU0757428866.USD","LU1815336091.USD","BK4121","LU0128526141.USD","CRL","BK4530","IE00BFMHRM44.USD","BK4588","BK4585","LU0390134368.USD"],"gpt_icon":0},{"id":"2614053420","title":"Charles River Labs Is Maintained at Neutral by UBS","url":"https://stock-news.laohu8.com/highlight/detail?id=2614053420","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2614053420?lang=en_us&edition=fundamental","pubTime":"2026-02-26 04:27","pubTimestamp":1772051220,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/CRL/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  February 25, 2026 15:27 ET (20:27 GMT)","market":"other","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0390134368.USD","LU0757428866.USD","LU1815336091.USD","BK4121","BK4585","BK4588","CRL","LU0029874061.USD","LU0128526141.USD","IE00BFMHRM44.USD","BK4530"],"gpt_icon":0},{"id":"2614803545","title":"UBS Adjusts Price Target on Charles River Laboratories International to $175 From $170, Maintains Neutral Rating","url":"https://stock-news.laohu8.com/highlight/detail?id=2614803545","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2614803545?lang=en_us&edition=fundamental","pubTime":"2026-02-25 22:46","pubTimestamp":1772030770,"startTime":"0","endTime":"0","summary":"Charles River Laboratories International (CRL) has an average rating of overweight and mean price target of $200.21, according to analysts polled by FactSet.(MT Newswires covers equity, commodity and ","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["CRL"],"gpt_icon":0},{"id":"2614082365","title":"Charles River raises annual profit view as it sells underperforming assets","url":"https://stock-news.laohu8.com/highlight/detail?id=2614082365","media":"Reuters","labels":["event"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2614082365?lang=en_us&edition=fundamental","pubTime":"2026-02-25 20:55","pubTimestamp":1772024142,"startTime":"0","endTime":"0","summary":"Feb 25  - Contract drug developer Charles River Laboratories CRL.N raised its 2026 profit forecast on Wednesday, after it announced the sales of some underperforming assets to peer IQVIA IQV.N and private equity firm GI Partners.The company had unveiled plans to divest underperforming assets in","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260225:nL4N3ZL150:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"event","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU1201861165.SGD","CRL","LU1989764748.USD","LU1989764664.SGD","LU0757428866.USD","LU1261432733.SGD","BK4585","LU0130517989.USD","LU0477156953.USD","LU0980610538.SGD","LU0528227936.USD","ADT","LU0130102774.USD","LU0198837287.USD","LU1791710582.SGD","LU0128526141.USD","LU0648001328.SGD","BK4192","LU1791710400.SGD","LU1815336091.USD","LU0029874061.USD","BK4165","LU0477156797.USD","LU1201861249.SGD","LU0130518102.USD","LU0130103400.USD","LU0390134368.USD","BK4121","IQV","BK4588","BK4530","IE00BFMHRM44.USD","LU0648000940.SGD","LU0882574055.USD"],"gpt_icon":0},{"id":"2614842150","title":"Iqvia to acquire certain discovery services assets from Charles River","url":"https://stock-news.laohu8.com/highlight/detail?id=2614842150","media":"TIPRANKS","labels":["corporation","merge"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2614842150?lang=en_us&edition=fundamental","pubTime":"2026-02-25 20:36","pubTimestamp":1772022982,"startTime":"0","endTime":"0","summary":"Iqvia (IQV) announced it has entered into an agreement to acquire certain discovery services assets from Charles River Laboratories (CRL). These as...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/iqvia-to-acquire-certain-discovery-services-assets-from-charles-river-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/iqvia-to-acquire-certain-discovery-services-assets-from-charles-river-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"corporation,merge","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["LU0130102774.USD","LU0528227936.USD","LU0130103400.USD","LU0390134368.USD","CRL","LU0128526141.USD","LU1815336091.USD","BK4585","BK4530","LU1791710582.SGD","LU1261432733.SGD","LU0130517989.USD","LU1791710400.SGD","LU0029874061.USD","BK4121","LU0198837287.USD","IQV","BK4588","LU0648000940.SGD","LU1201861165.SGD","LU1989764664.SGD","LU1989764748.USD","LU0882574055.USD","LU0648001328.SGD","LU1201861249.SGD","LU0477156953.USD","LU0980610538.SGD","IE00BFMHRM44.USD","LU0757428866.USD","LU0477156797.USD","LU0130518102.USD"],"gpt_icon":0},{"id":"2614990081","title":"GUIDANCE: (CRL) Charles River Laboratories Expects 2026 Adjusted EPS Including Impact of Planned Divestitures Range $10.80 - $11.30","url":"https://stock-news.laohu8.com/highlight/detail?id=2614990081","media":"MT Newswires Live","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2614990081?lang=en_us&edition=fundamental","pubTime":"2026-02-25 20:13","pubTimestamp":1772021623,"startTime":"0","endTime":"0","summary":"GUIDANCE: (CRL) Charles River Laboratories Expects 2026 Adjusted EPS Including Impact of Planned Divestitures Range $10.80 - $11.30","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["CRL.AU","CRL"],"gpt_icon":0},{"id":"2614508970","title":"Charles River signs deals to sell European Discovery Services assets and CDMO and Cell Solutions businesses","url":"https://stock-news.laohu8.com/highlight/detail?id=2614508970","media":"Reuters","labels":["event"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2614508970?lang=en_us&edition=fundamental","pubTime":"2026-02-25 20:02","pubTimestamp":1772020966,"startTime":"0","endTime":"0","summary":"Charles River Laboratories International has signed definitive agreements to sell its CDMO and Cell Solutions businesses to GI Partners, primarily for future contingent performance-based payments, and to sell certain European Discovery Services assets to IQVIA for about $145 million in cash plus up to $10 million in additional payments. The divestitures, expected to close in the second quarter of 2026, include CDMO sites in Tennessee, Maryland and the U.K., a Cell Solutions site in California, and five European discovery services sites. Charles River updated its 2026 outlook to reflect the deals, expecting reported revenue to fall by slightly more than $200 million while improving non-GAAP operating margin by at least 100 basis points and adding about $0.10 to non-GAAP EPS for the partial year.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. 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