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Annovis Bio, Inc.

2.01

-0.0200-0.99%

Pre-market: 1.99-0.0169-0.84%04:29 EDT

Volume:360.42K

Turnover:725.53K

Market Cap:56.99M

PE:-1.43

High:2.05

Open:2.03

Low:1.96

Close:2.03

52wk High:5.50

52wk Low:1.11

Shares:28.36M

Float Shares:24.26M

Volume Ratio:0.76

T/O Rate:1.49%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-1.4040

EPS(LYR):-1.4040

ROE:-220.61%

ROA:-106.03%

PB:3.38

PE(LYR):-1.43

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Overview Company News Filings

Annovis Bio Inc - CEO Maria Maccecchini to Serve as Acting CFO Until Replacement Is Identified - SEC Filing

THOMSON REUTERS

Annovis Bio Inc - Mark Guerin Steps Down as CFO Effective March 23, 2026 - SEC Filing

THOMSON REUTERS

Annovis Bio CFO Mark Guerin departs; CEO Maria Maccecchini becomes acting CFO effective March 23, 2026

Annovis Bio enters partnership with NeuroRPM

Annovis Bio partners with NeuroRPM for AI wearable monitoring in Parkinson’s trial

Annovis Bio partners with NeuroRPM to deploy FDA-cleared AI digital biomarkers in Parkinson’s study

Neurorpm to Deploy AI-Enabled Digital Biomarker Monitoring for Annovis Bio's Parkinson's Disease Clinical Trial

THOMSON REUTERS

Analysts Offer Insights on Healthcare Companies: Warby Parker (WRBY) and Annovis Bio (ANVS)

BRIEF-Annovis Provides Corporate Updates And Reports Fiscal Year 2025 Financial Results

Annovis Bio reports FY25 EPS ($1.40) vs. ($2.31) last year

Annovis Bio Q4 EPS $(0.39) Misses $(0.34) Estimate

Annovis Bio Inc: Estimates That Its Current Cash and Cash Equivalents Will Enable It to Fund Its Operations Into Q3 of 2026

THOMSON REUTERS

Press Release: Annovis Provides Corporate Updates and Reports Fiscal Year 2025 Financial Results

Annovis Bio FY 2025 net loss widens 17% to USD 28.86 million, interest income rises 111% to USD 0.7 million

Annovis Bio to Present Twice at AD/PD 2026 International Conference

Annovis Bio: Advancing Phase 3 Neurodegeneration Programs Create Attractive Risk‑Reward Supporting Buy Rating

Annovis Bio Advances Alzheimer’s Phase 3 Trial After Safety Nod

Annovis Bio Inc - Dsmb Finds No Safety Concerns, Trial to Continue as Planned

THOMSON REUTERS

Annovis Secures DSMB Approval to Advance Pivotal Phase 3 Trial of Buntanetap in Alzheimer’s Disease

Annovis Bio Hosts Regulation FD Investor Information Webinar

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2026","url":"https://stock-news.laohu8.com/highlight/detail?id=2622007478","media":"Reuters","labels":["executive"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2622007478?lang=en_us&edition=fundamental","pubTime":"2026-03-26 05:19","pubTimestamp":1774473582,"startTime":"0","endTime":"0","summary":"Mark Guerin is no longer employed as CFO at Annovis Bio, effective March 23, 2026.His departure was not related to any disagreement over the company’s operations, policies, or practices.The board is expected to appoint CEO Maria Maccecchini as acting CFO while a replacement is identified.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Annovis Bio Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on March 25, 2026, and is solely responsible for the information contained therein.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260325:nNDL8Jlkrg:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"executive","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["ANVS","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2620192247","title":"Annovis Bio enters partnership with 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dat...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/annovis-bio-enters-partnership-with-neurorpm-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/annovis-bio-enters-partnership-with-neurorpm-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"corporation","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["ANVS","BK4588","BK4585","LABU","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2620242663","title":"Annovis Bio partners with NeuroRPM for AI wearable monitoring in Parkinson’s trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2620242663","media":"Reuters","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2620242663?lang=en_us&edition=fundamental","pubTime":"2026-03-19 19:31","pubTimestamp":1773919878,"startTime":"0","endTime":"0","summary":"Annovis partnered with NeuroRPM to use NeuroRPM’s FDA-cleared wearable platform for digital biomarker monitoring in Annovis’s ANVS-25002 open-label Parkinson’s disease clinical trial.The NeuroRPM platform uses Apple Watch data to passively collect and analyze movement during daily activities.Monitoring is intended to provide continuous measurement of Parkinson’s motor symptoms including bradykinesia, tremor, and dyskinesia.The ANVS-25002 study is expected to enroll about 500 participants across multiple clinical sites, with eligible participants able to opt into the digital monitoring program.After the study, participants may continue using NeuroRPM for clinical monitoring by prescription.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260319:nNDL743Hj0:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"corporation","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU2095319765.USD","IE00BN0W2V16.EUR","NDAQ","IE00BKPKM429.USD","SG9999014005.SGD","BK4588","BK4139","IE00BN0W2W23.USD","SG9999014013.SGD","LU2210149790.SGD","IE00B3QW5Z07.USD","IE00BN0W2T93.GBP","ANVS","LU2210150020.SGD","IE00B64PRP62.GBP","BK4585","IE00BGHQF748.EUR","SG9999014021.USD","SG9999014039.USD","LU0314104364.USD","BK4112"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2620425092","title":"Annovis Bio partners with NeuroRPM to deploy FDA-cleared AI digital biomarkers in Parkinson’s study","url":"https://stock-news.laohu8.com/highlight/detail?id=2620425092","media":"Reuters","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2620425092?lang=en_us&edition=fundamental","pubTime":"2026-03-19 19:31","pubTimestamp":1773919876,"startTime":"0","endTime":"0","summary":"Annovis partnered with NeuroRPM to deploy an FDA-cleared AI platform for movement-data collection in an ongoing Parkinson’s disease study.The platform is intended to monitor bradykinesia, tremor, and dyskinesia using mobile and wearable applications.Annovis said the NeuroRPM data will be used as a digital biomarker to track symptom changes during the study.The open-label study is enrolling across 25 U.S. sites and is designed to evaluate buntanetap over 36 months.The trial has enrolled 90 of an estimated 500 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(WRBY) and Annovis Bio (ANVS)","url":"https://stock-news.laohu8.com/highlight/detail?id=2620826966","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2620826966?lang=en_us&edition=fundamental","pubTime":"2026-03-19 02:30","pubTimestamp":1773858626,"startTime":"0","endTime":"0","summary":"There’s a lot to be optimistic about in the Healthcare sector as 2 analysts just weighed in on Warby Parker (WRBY) and Annovis Bio (ANVS) with 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Maccecchi...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/annovis-bio-reports-fy25-eps-1-40-vs-2-31-last-year-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/annovis-bio-reports-fy25-eps-1-40-vs-2-31-last-year-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["ANVS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2619570494","title":"Annovis Bio Q4 EPS $(0.39) Misses $(0.34) 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This is a 9.3 percent increase over losses of $(0.43) per share from the same","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.benzinga.com/news/earnings/26/03/51265214/annovis-bio-q4-eps-0-39-misses-0-34-estimate","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["ANVS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2619570634","title":"Annovis Bio Inc: Estimates That Its Current Cash and Cash Equivalents Will Enable It to Fund Its Operations Into Q3 of 2026","url":"https://stock-news.laohu8.com/highlight/detail?id=2619570634","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2619570634?lang=en_us&edition=fundamental","pubTime":"2026-03-16 19:30","pubTimestamp":1773660601,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260316:nTUA6G3G39:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","ANVS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2619457045","title":"Press Release: Annovis Provides Corporate Updates and Reports Fiscal Year 2025 Financial Results","url":"https://stock-news.laohu8.com/highlight/detail?id=2619457045","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2619457045?lang=en_us&edition=fundamental","pubTime":"2026-03-16 19:30","pubTimestamp":1773660600,"startTime":"0","endTime":"0","summary":"In 2025, Annovis achieved a significant milestone in its clinical development program with the initiation of a pivotal Phase 3 clinical trial in early AD. The year was largely dedicated to the activation of clinical sites and the enrollment of participants across the United States. The Company also reported encouraging data from both its previous Alzheimer's and Parkinson's programs, demonstrating a potential disease-modifying signal for buntanetap through reductions in biomarkers of amyloid and tau pathology, neuroinflammation, and neurodegeneration. Building on this momentum, Annovis recently initiated an open-label extension  study in PD.\"The year 2025 was a landmark period for Annovis, one in which we took decisive steps toward bringing buntanetap to patients,\" said Maria Maccecchini, Ph.D., Founder and CEO of Annovis. \"We initiated our pivotal Phase 3 AD study and later launched an OLE PD study, both critical milestones on the path to an NDA submission. 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FY 2025 research and development expense rose 26% to USD 25.22 million, driven mainly by higher costs for patients in its Phase 3 Alzheimer’s trial and increased bioanalytical work. FY 2025 general and administrative expense fell 33% to USD 4.48 million, primarily due to lower stock-based compensation, stock listing and transfer fees, and corporate legal costs. FY 2025 interest income increased 111% to USD 0.7 million, reflecting higher cash and cash equivalents following a February 2025 public offering. Annovis ended FY 2025 with USD 19.5 million in cash and cash equivalents and said it expects this to fund operations into the third quarter of 2026, while noting it does not have sufficient capital to fund the next 12 months beyond the filing date.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260313:nNDL12zxh5:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","ANVS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2616400553","title":"Annovis Bio to Present Twice at AD/PD 2026 International Conference","url":"https://stock-news.laohu8.com/highlight/detail?id=2616400553","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2616400553?lang=en_us&edition=fundamental","pubTime":"2026-03-03 21:02","pubTimestamp":1772542961,"startTime":"0","endTime":"0","summary":"Annovis Bio to Present Twice at AD/PD 2026 International Conference               Annovis Bio Inc. will attend the AD/PD 2026 International Conference, held March 17-21, 2026, in Copenhagen, Denmark, ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260303:nNDL1HS2WS:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SG9999014013.SGD","LU2095319765.USD","ANVS","LU0314104364.USD","IE00BKPKM429.USD","LU2210149790.SGD","BK4112","SG9999014021.USD","NDAQ","SG9999014005.SGD","BK4139","IE00B3QW5Z07.USD","BK4585","IE00B64PRP62.GBP","IE00BGHQF748.EUR","SG9999014039.USD","LU2210150020.SGD","BK4588"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2613292091","title":"Annovis Bio: Advancing Phase 3 Neurodegeneration Programs Create Attractive Risk‑Reward Supporting Buy Rating","url":"https://stock-news.laohu8.com/highlight/detail?id=2613292091","media":"TIPRANKS","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2613292091?lang=en_us&edition=fundamental","pubTime":"2026-02-21 04:45","pubTimestamp":1771620328,"startTime":"0","endTime":"0","summary":"Jason McCarthy, an analyst from Maxim Group, maintained the Buy rating on Annovis Bio. The associated price target is $8.00. Jason McCarthy has giv...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/ratings/annovis-bio-advancing-phase-3-neurodegeneration-programs-create-attractive-risk‑reward-supporting-buy-rating-ratings-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/ratings/annovis-bio-advancing-phase-3-neurodegeneration-programs-create-attractive-risk‑reward-supporting-buy-rating-ratings-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["ANVS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2610927693","title":"Annovis Bio Advances Alzheimer’s Phase 3 Trial After Safety Nod","url":"https://stock-news.laohu8.com/highlight/detail?id=2610927693","media":"TIPRANKS","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2610927693?lang=en_us&edition=fundamental","pubTime":"2026-02-12 22:35","pubTimestamp":1770906929,"startTime":"0","endTime":"0","summary":"The latest announcement is out from Annovis Bio ( ($ANVS) ). On February 12, 2026, Annovis Bio said an independent Data and Safety Monitoring Board...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/company-announcements/annovis-bio-advances-alzheimers-phase-3-trial-after-safety-nod?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/company-announcements/annovis-bio-advances-alzheimers-phase-3-trial-after-safety-nod?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["ANVS","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2610992996","title":"Annovis Bio Inc - Dsmb Finds No Safety Concerns, Trial to Continue as Planned","url":"https://stock-news.laohu8.com/highlight/detail?id=2610992996","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2610992996?lang=en_us&edition=fundamental","pubTime":"2026-02-12 21:00","pubTimestamp":1770901205,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260212:nTUA3HJRSV:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["ANVS","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2610927854","title":"Annovis Secures DSMB Approval to Advance Pivotal Phase 3 Trial of Buntanetap in Alzheimer’s Disease","url":"https://stock-news.laohu8.com/highlight/detail?id=2610927854","media":"GlobeNewswire","labels":["executive"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2610927854?lang=en_us&edition=fundamental","pubTime":"2026-02-12 21:00","pubTimestamp":1770901200,"startTime":"0","endTime":"0","summary":"MALVERN, Pa., Feb.  12, 2026  (GLOBE NEWSWIRE) -- Annovis Bio, Inc. (NYSE: ANVS) (“Annovis” or the “Company”), a Phase 3 clinical-stage biotechnology company developing the investigational oral therap","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2026/02/12/3237130/0/en/Annovis-Secures-DSMB-Approval-to-Advance-Pivotal-Phase-3-Trial-of-Buntanetap-in-Alzheimer-s-Disease.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"executive","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["AD","ANVS","LU1169589451.USD","BK4139","LU1169590202.USD","PD","BK4132","BK4023"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2607072548","title":"Annovis Bio Hosts Regulation FD Investor Information Webinar","url":"https://stock-news.laohu8.com/highlight/detail?id=2607072548","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2607072548?lang=en_us&edition=fundamental","pubTime":"2026-01-29 05:50","pubTimestamp":1769637041,"startTime":"0","endTime":"0","summary":"Annovis Bio ( ($ANVS) ) has shared an announcement. On January 28, 2026, Annovis Bio, Inc. held a webinar, supported by a prepared presentation tha...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/company-announcements/annovis-bio-hosts-regulation-fd-investor-information-webinar?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/company-announcements/annovis-bio-hosts-regulation-fd-investor-information-webinar?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","III","BK4134","ANVS"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":20,"totalPage":4,"pageCount":1,"totalSize":66,"code":"91000000","status":"200"}]}}