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Verastem

5.60

-0.2800-4.76%

Volume:1.30M

Turnover:7.37M

Market Cap:307.72M

PE:-1.60

High:5.84

Open:5.78

Low:5.58

Close:5.88

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Overview Company News Filings

Verastem Exercises Option Early to License Cancer Drug VS-7375 From GenFleet

MT Newswires Live

Verastem exercises early option to license VS-7375 from GenFleet Therapeutics

BRIEF-Verastem Oncology Exercises Option Early to License VS-7375

Verastem Oncology Exercises Option Early to License VS-7375, an Oral Kras G12d (on/off) Inhibitor, From Genfleet Therapeutics and Provides Preliminary Clinical Update on Phase 1 Study in China

THOMSON REUTERS

Verastem Inc - to File U.S. Ind Application for VS-7375 in Q1 2025

THOMSON REUTERS

Verastem Oncology Exercises Option Early to License VS-7375, an Oral KRAS G12D (ON/OFF) Inhibitor, from GenFleet Therapeutics and Provides Preliminary Clinical Update on Phase 1 Study in China

BRIEF-Verastem Oncology Announces Debt Refinancing with Oberland Capital and Strategic Commercialization Partnership with IQVIA

Verastem Oncology Announces Debt Refinancing With Oberland Capital and Strategic Commercialization Partnership With IQVIA to Support Potential Launch in Recurrent Kras Mutant Low-Grade Serous Ovarian Cancer in Mid-2025

THOMSON REUTERS

Verastem Inc - Secures $150 Million Credit Facility and $7.5 Million Equity Investment

THOMSON REUTERS

Verastem Oncology Announces Debt Refinancing with Oberland Capital and Strategic Commercialization Partnership with IQVIA to Support Potential Launch in Recurrent KRAS Mutant Low-Grade Serous Ovarian Cancer in Mid-2025

BRIEF-Verastem Oncology Announces Inducement Grants Under Nasdaq Listing Rule 5635(C)(4)

Verastem Oncology Announces Inducement Grants Under Nasdaq Listing Rule 5635(C)(4)

THOMSON REUTERS

Verastem price target raised to $16 from $13 at RBC Capital

RBC Raises Price Target on Verastem to $16 From $13, Keeps Outperform, Speculative Risk

MT Newswires Live

VSTM Up as NDA for Ovarian Cancer Combo Gets FDA's Priority Review Tag

Verastem Shares Soar on FDA Priority Review of Cancer Treatment

Sector Update: Health Care Stocks Lower in Afternoon Trading

MT Newswires Live

US Equity Indexes Decline After Midday Tuesday as 2024 Draws to Close

MT Newswires Live

Verastem Shares Surge Over 24% on FDA Acceptance of Cancer Therapy Application

Verastem Shares up 32% After FDA Grants Priority Review for Ovarian Cancer Combo Therapy

THOMSON REUTERS

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Exercises Option Early to License Cancer Drug VS-7375 From GenFleet","url":"https://stock-news.laohu8.com/highlight/detail?id=2503572740","media":"MT Newswires Live","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2503572740?lang=en_us&edition=fundamental","pubTime":"2025-01-14 23:20","pubTimestamp":1736868024,"startTime":"0","endTime":"0","summary":"Verastem  exercised an option early to license from GenFleet Therapeutics the investigational drug VS-7375, which is in phase 1 development in China for potential treatment of advanced solid tumors in pancreatic, colorectal and non-small cell lung cances.A US investigational new drug application for VS-7375 is expected to be filed in Q1 with plans to start a phase 1/2a study in the middle of this year, Verastem said Tuesday in a statement.The license gives Verastem global development and commercialization rights for VS-7375 outside of the GenFleet markets of mainland China, Hong Kong, Macau and Taiwan.Preliminary results from a phase 1 study of VS-7375 conducted by GenFleet in China showed \"partial responses, including patients with pancreatic and lung cancers,\" Verastem said.GenFleet had announced 26 people were treated with VS-7375 in the phase 1 dose-escalation trial, Verastem said.Verastem shares rose 4.1% in recent Tuesday trading.Price: 5.56, Change: +0.22, Percent Change: +4.11","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"corporation","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["VSTM","BK4139","BK4085","VS"],"gpt_icon":0},{"id":"2503524714","title":"Verastem exercises early option to license VS-7375 from GenFleet Therapeutics","url":"https://stock-news.laohu8.com/highlight/detail?id=2503524714","media":"TIPRANKS","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2503524714?lang=en_us&edition=fundamental","pubTime":"2025-01-14 20:35","pubTimestamp":1736858109,"startTime":"0","endTime":"0","summary":"Verastem (VSTM) announced it has exercised early the option to license from GenFleet Therapeutics VS-7375, an oral and selective KRAS G12D inhibito...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/verastem-exercises-early-option-to-license-vs-7375-from-genfleet-therapeutics?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/verastem-exercises-early-option-to-license-vs-7375-from-genfleet-therapeutics?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"corporation","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","BK4085","LENZ","VS","VSTM"],"gpt_icon":0},{"id":"2503752419","title":"BRIEF-Verastem Oncology Exercises Option Early to License VS-7375","url":"https://stock-news.laohu8.com/highlight/detail?id=2503752419","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2503752419?lang=en_us&edition=fundamental","pubTime":"2025-01-14 20:33","pubTimestamp":1736857989,"startTime":"0","endTime":"0","summary":"Jan 14  - Verastem Inc   :   * VERASTEM ONCOLOGY EXERCISES OPTION EARLY TO LICENSE VERSUS-7375, AN ORAL KRAS G12D  INHIBITOR, FROM GENFLEET THERAPEUTICS AND PROVIDES PRELIMINARY CLINICAL UPDATE ON PHASE 1 STUDY IN CHINA   * VERASTEM INC - TO FILE U.S. IND APPLICATION FOR VERSUS-7375 IN Q1 2025Source text:    Further company coverage:    ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.rkd.refinitiv.com/api/News/News.svc/REST/News_1/RetrieveStoryML_1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["VS","LU1978683503.SGD","LU2298322129.HKD","BK4585","BK4085","LU2357305700.SGD","LU1720051108.HKD","LU0724618433.USD","BK4512","LU1861219969.SGD","BK4139","LU0348723411.USD","LU1861220033.SGD","BK4588","IE00BD6J9T35.USD","LU1854103824.USD","VSTM","LU1861214812.USD","LU1720051017.SGD","LU0124384867.USD","LU1548497426.USD","LU1861215975.USD","LU1854104046.USD","LU2360107325.USD","IE00BZ199S13.USD","BK4141"],"gpt_icon":0},{"id":"2503524922","title":"Verastem Oncology Exercises Option Early to License VS-7375, an Oral Kras 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Inc - to File U.S. Ind Application for VS-7375 in Q1 2025","url":"https://stock-news.laohu8.com/highlight/detail?id=2503152497","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2503152497?lang=en_us&edition=fundamental","pubTime":"2025-01-14 20:30","pubTimestamp":1736857801,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250114:nTUA3MYDVX:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","VSTM"],"gpt_icon":0},{"id":"2503952279","title":"Verastem Oncology Exercises Option Early to License VS-7375, an Oral KRAS G12D (ON/OFF) Inhibitor, from GenFleet Therapeutics and Provides Preliminary Clinical Update on Phase 1 Study in China","url":"https://stock-news.laohu8.com/highlight/detail?id=2503952279","media":"Business Wire","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2503952279?lang=en_us&edition=fundamental","pubTime":"2025-01-14 20:30","pubTimestamp":1736857800,"startTime":"0","endTime":"0","summary":"VS-7375 is a potential best-in-class oral and selective KRAS G12D  inhibitor currently in Phase 1 development in China in advanced KRAS G12D mutant solid tumors; Verastem anticipates filing a U.S. IND application for VS-7375 during Q1 2025 and expects to initiate a Phase 1/2a study mid-2025. License establishes global development and commercialization rights for Verastem for VS-7375 outside of China, Hong Kong, Macau, and Taiwan. \"Bringing VS-7375 formally into our pipeline allows us to leverage our scientific and development expertise in the RAS/MAPK-pathway to target KRAS G12D - the most prevalent KRAS mutation in human cancers,\" said Dan Paterson, chief executive officer at Verastem Oncology. \"Our decision to exercise the option early for VS-7375 was based on the safety, pharmacokinetics and efficacy data to date in the Phase 1 study in China, which are in line with our expectations and, importantly, indicate that patients are generally achieving oral bioavailability with exposures ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/verastem-oncology-exercises-option-early-123000294.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LU2357305700.SGD","LU1861215975.USD","LU0348723411.USD","VS","BK4139","BK4588","BK4512","IE00BZ199S13.USD","LU0724618433.USD","BK4141","IE00BD6J9T35.USD","ON","LU1978683503.SGD","LU1720051017.SGD","LU1861220033.SGD","LU2360107325.USD","LU2298322129.HKD","BK4085","BK4585","LU1854104046.USD","LU1861219969.SGD","LU1548497426.USD","LU1854103824.USD","LU1861214812.USD","LENZ","LU1720051108.HKD","VSTM","LU0124384867.USD"],"gpt_icon":0},{"id":"2503130262","title":"BRIEF-Verastem Oncology Announces Debt Refinancing with Oberland Capital and Strategic Commercialization Partnership with IQVIA","url":"https://stock-news.laohu8.com/highlight/detail?id=2503130262","media":"Reuters","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2503130262?lang=en_us&edition=fundamental","pubTime":"2025-01-13 21:50","pubTimestamp":1736776200,"startTime":"0","endTime":"0","summary":"Jan 13  - Verastem Inc   :   * VERASTEM ONCOLOGY ANNOUNCES DEBT REFINANCING WITH OBERLAND CAPITAL AND STRATEGIC COMMERCIALIZATION PARTNERSHIP WITH IQVIA TO SUPPORT POTENTIAL LAUNCH IN RECURRENT KRAS MUTANT LOW-GRADE SEROUS OVARIAN CANCER IN MID-2025   * VERASTEM INC - SECURES $150 MILLION CREDIT FACILITY AND $7.5 MILLION EQUITY INVESTMENTSource text:    Further company coverage:    ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.rkd.refinitiv.com/api/News/News.svc/REST/News_1/RetrieveStoryML_1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"corporation","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0528227936.USD","LU1989764748.USD","LU0130518102.USD","LU0980610538.SGD","LU1201861165.SGD","LU1989764664.SGD","LU0477156797.USD","LU1261432733.SGD","LU0130517989.USD","LU1201861249.SGD","VSTM","LU0130102774.USD","BK4585","BK4139","LU0198837287.USD","LU0648000940.SGD","BK4588","IQV","LU0648001328.SGD","LU0130103400.USD","LU0477156953.USD","BK4121","LU1791710582.SGD","LU1791710400.SGD","BK4530","LU0882574055.USD"],"gpt_icon":0},{"id":"2503305981","title":"Verastem Oncology Announces Debt Refinancing With Oberland Capital and Strategic Commercialization Partnership With IQVIA to Support Potential Launch in Recurrent Kras Mutant Low-Grade Serous Ovarian Cancer in Mid-2025","url":"https://stock-news.laohu8.com/highlight/detail?id=2503305981","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2503305981?lang=en_us&edition=fundamental","pubTime":"2025-01-13 20:30","pubTimestamp":1736771401,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250113:nTUA2BFWQF:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","VSTM"],"gpt_icon":0},{"id":"2503056743","title":"Verastem Inc - Secures $150 Million Credit Facility and $7.5 Million Equity Investment","url":"https://stock-news.laohu8.com/highlight/detail?id=2503056743","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2503056743?lang=en_us&edition=fundamental","pubTime":"2025-01-13 20:30","pubTimestamp":1736771401,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250113:nTUA2BFWQF:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","VSTM"],"gpt_icon":0},{"id":"2503185305","title":"Verastem Oncology Announces Debt Refinancing with Oberland Capital and Strategic Commercialization Partnership with IQVIA to Support Potential Launch in Recurrent KRAS Mutant Low-Grade Serous Ovarian Cancer in Mid-2025","url":"https://stock-news.laohu8.com/highlight/detail?id=2503185305","media":"Business Wire","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2503185305?lang=en_us&edition=fundamental","pubTime":"2025-01-13 20:30","pubTimestamp":1736771400,"startTime":"0","endTime":"0","summary":"Company cash, cash equivalents, and investments of $88.8 million as of December 31, 2024; pro forma cash position of $128.6 million including debt refinancing and equity issuance provides cash runway beyond FDA approval. \"The Oberland Capital transaction, coupled with our strategic partnership with IQVIA, enables us to launch avutometinib plus defactinib for recurrent LGSOC from a position of financial strength and with commercialization solutions to accelerate our launch. The additional capital will help us create a commercial revenue stream to support our pipeline with new approaches for patients needing treatments for complex and rare cancers,\" said Dan Paterson, president and chief executive officer of Verastem Oncology.In addition, the Company has entered into a stock purchase agreement with affiliates of Oberland Capital for the private placement of 1,416,939 shares of the Company’s common stock issued at closing, representing $7.5 million of gross proceeds based on the trailing ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/verastem-oncology-announces-debt-refinancing-123000097.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"corporation","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LU0980610538.SGD","LU0648000940.SGD","LU1201861249.SGD","BK4585","LU0130103400.USD","LU0477156797.USD","LU0130517989.USD","LU1261432733.SGD","BK4530","LU1791710400.SGD","IQV","LU0477156953.USD","LU0528227936.USD","LU0198837287.USD","LU0130518102.USD","LU1201861165.SGD","LU0130102774.USD","LU0882574055.USD","BK4121","VSTM","LU1791710582.SGD","BK4588","BK4139","LU0648001328.SGD","LU1989764664.SGD","LU1989764748.USD"],"gpt_icon":0},{"id":"2501472924","title":"BRIEF-Verastem Oncology Announces Inducement Grants Under Nasdaq Listing Rule 5635(C)(4)","url":"https://stock-news.laohu8.com/highlight/detail?id=2501472924","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2501472924?lang=en_us&edition=fundamental","pubTime":"2025-01-08 20:51","pubTimestamp":1736340682,"startTime":"0","endTime":"0","summary":"BRIEF-Verastem Oncology Announces Inducement Grants Under Nasdaq Listing Rule 5635Jan 8  - Verastem Inc VSTM.O:VERASTEM ONCOLOGY ANNOUNCES INDUCEMENT GRANTS UNDER NASDAQ LISTING RULE 5635Source text: nBwbVW1zFaFurther company coverage: VSTM.O ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250108:nTUABC4JPG:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","VSTM"],"gpt_icon":0},{"id":"2501726196","title":"Verastem Oncology Announces Inducement Grants Under Nasdaq Listing Rule 5635(C)(4)","url":"https://stock-news.laohu8.com/highlight/detail?id=2501726196","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2501726196?lang=en_us&edition=fundamental","pubTime":"2025-01-08 20:30","pubTimestamp":1736339401,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250108:nTUABC4JPG:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["VSTM","BK4139"],"gpt_icon":0},{"id":"2501720416","title":"Verastem price target raised to $16 from $13 at RBC Capital","url":"https://stock-news.laohu8.com/highlight/detail?id=2501720416","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2501720416?lang=en_us&edition=fundamental","pubTime":"2025-01-07 21:51","pubTimestamp":1736257870,"startTime":"0","endTime":"0","summary":"RBC Capital raised the firm’s price target on Verastem (VSTM) to $16 from $13 and keeps an Outperform rating on the shares as part of a broader res...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/verastem-price-target-raised-to-16-from-13-at-rbc-capital?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/verastem-price-target-raised-to-16-from-13-at-rbc-capital?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["VSTM"],"gpt_icon":0},{"id":"2501120580","title":"RBC Raises Price Target on Verastem to $16 From $13, Keeps Outperform, Speculative Risk","url":"https://stock-news.laohu8.com/highlight/detail?id=2501120580","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2501120580?lang=en_us&edition=fundamental","pubTime":"2025-01-07 20:51","pubTimestamp":1736254280,"startTime":"0","endTime":"0","summary":"Verastem (VSTM) has an average rating of buy and mean price target of $12.29, according to analysts polled by FactSet.(MT Newswires covers equity, commodity and economic research from major banks and ","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate","earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["VSTM"],"gpt_icon":0},{"id":"2500007971","title":"VSTM Up as NDA for Ovarian Cancer Combo Gets FDA's Priority Review Tag","url":"https://stock-news.laohu8.com/highlight/detail?id=2500007971","media":"Zacks","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2500007971?lang=en_us&edition=fundamental","pubTime":"2025-01-02 22:56","pubTimestamp":1735829760,"startTime":"0","endTime":"0","summary":"Both avutometinib and defactinib have been in-licensed by Verastem from other pharmaceutical companies. Avutometinib is an RAF/MEK clamp, while defactinib is a best-in-class selective FAK inhibitor.In the past three months, shares of Verastem have surged 86.6% against the industry’s 9.5% decline.More on the FDA Acceptance of Avutometinib NDA for LGSOC. At present, there are no FDA-approved treatments specifically for LGSOC, a rare and distinct type of ovarian cancer with unique biology and treatment responses compared to high-grade serous ovarian cancer, representing a huge unmet medical need. Per Verastem, an estimated 6,000-8,000 women in theUnited Statesand 80,000 worldwide suffer from this disease. The standard of care treatment includes hormone therapy and chemotherapy.Currently, the company is enrolling patients with recurrent LGSOC regardless of KRAS mutation status in the global phase III RAMP 301 study, which is expected to serve as a confirmatory study for the initial indica","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/vstm-nda-ovarian-cancer-combo-145600394.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["CSTL","VSTM","CTMX","BK4139","SPRO","BK4196"],"gpt_icon":0},{"id":"2500064962","title":"Verastem Shares Soar on FDA Priority Review of Cancer Treatment","url":"https://stock-news.laohu8.com/highlight/detail?id=2500064962","media":"Dow Jones","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2500064962?lang=en_us&edition=fundamental","pubTime":"2025-01-01 03:00","pubTimestamp":1735671600,"startTime":"0","endTime":"0","summary":"Shares of Verastem surged after the company's new cancer treatment got priority review from regulators.The stock was up 46% at $5.37 on Tuesday. Shares are still down 35% since the start of the year.The company said after the bell on Monday that the Food and Drug Administration has given priority review to its treatment for recurrent low-grade serous ovarian cancer.The FDA's decision is expected by June 30, 2025. If approved, it would be the first treatment specifically for this type of cancer, the company said.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["VSTM","BK4139"],"gpt_icon":0},{"id":"2500460746","title":"Sector Update: Health Care Stocks Lower in Afternoon Trading","url":"https://stock-news.laohu8.com/highlight/detail?id=2500460746","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2500460746?lang=en_us&edition=fundamental","pubTime":"2025-01-01 02:51","pubTimestamp":1735671116,"startTime":"0","endTime":"0","summary":"Health care stocks fell Tuesday afternoon with the NYSE Health Care Index down 0.2% and the Health Care Select Sector SPDR Fund  easing 0.1%.The iShares Biotechnology ETF  rose 0.1%.In corporate news, Verastem  shares jumped 46% after the US Food and Drug Administration accepted and granted priority review to a new drug application for its ovarian cancer drug and set an action date of June 30.Kazia Therapeutics  shares fell 37% after the company said it was considering options for its drug candidate paxalisib after the US Food and Drug Administration discouraged an accelerated approval process for the potential glioblastoma treatment.Sangamo Therapeutics  shares sank 55% after it said its partner Pfizer  decided not to proceed with further development of a new gene therapy to treat hemophilia A, a bleeding disorder.","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK7095","LU0234572021.USD","IE0002270589.USD","LU0225284248.USD","SG9999001176.USD","IE000M9KFDE8.USD","LU1057294990.SGD","PFE.AU","LU0122379950.USD","LU0225771236.USD","BK4599","BK4568","BK4556","IE00BLSP4452.SGD","BK4588","LU1066051498.USD","BK4534","LU1883839398.USD","BK4592","SG9999003800.SGD","BK4007","LU0306807586.USD","XLV","IE00B19Z3581.USD","IE00BLSP4239.USD","SG9999002224.SGD","LU0321505439.SGD","LU1066053197.SGD","SG9999002232.USD","BK4533","SG9999011175.SGD","SGMO","VSTM","IE00B19Z3B42.SGD","SG9999013999.USD","LU0321505868.SGD","IE00BBT3K403.USD","LU0868494617.USD","SG9999001176.SGD","LU0985481810.HKD","SGXZ57979304.SGD","BK4585","BK4139","LU0170899867.USD","PFE","LU0058720904.USD","LU1894683264.USD","IBB","KZIA","BK4550"],"gpt_icon":1},{"id":"2500430306","title":"US Equity Indexes Decline After Midday Tuesday as 2024 Draws to Close","url":"https://stock-news.laohu8.com/highlight/detail?id=2500430306","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2500430306?lang=en_us&edition=fundamental","pubTime":"2025-01-01 02:05","pubTimestamp":1735668315,"startTime":"0","endTime":"0","summary":"US benchmark stock indexes fell after midday Tuesday, continuing the previous session's losses on the last trading day of 2024.The Nasdaq slipped 0.9% to 19,314, the S&P 500 lost 0.6% to 5,874 and the","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["MNQmain","AFBI","PSQ","EQR","PFE.AU","LU1057294990.SGD","TQQQ","LU2756315318.SGD","QLD","QID",".IXIC","LU1201861165.SGD",".SPX","LU1935043023.USD","LU0708995401.HKD","LU0724617625.USD","PFE","LU0943347566.SGD","USAW.SI","LU2237957902.USD","LU2361044865.SGD","IE00B5949003.HKD","LU2463028550.USD","DXD","USJW.SI",".DJI","IE00B19Z8W00.USD","SGMO","NQmain","AMZN","NVIW.SI","SQQQ","DJX","SDOW","UDOW","BK4503","IE00BK4W5L77.USD","LU1145028129.USD","LU2247934214.USD","DDM","LU0823421416.USD","LU0061474705.USD","LU0127658192.USD","LU1084165304.USD","TSYW.SI","IE00BBT3K403.USD","SG9999017495.SGD","DOG","VSTM"],"gpt_icon":1},{"id":"2495611751","title":"Verastem Shares Surge Over 24% on FDA Acceptance of Cancer Therapy Application","url":"https://stock-news.laohu8.com/highlight/detail?id=2495611751","media":"GuruFocus.com","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2495611751?lang=en_us&edition=fundamental","pubTime":"2024-12-31 23:33","pubTimestamp":1735659209,"startTime":"0","endTime":"0","summary":"Following news that the U.S. Food and Drug Administration approved its New Drug Application for avutometinib in combination with defactinib to treat recurrent low-grade serous ovarian cancer in patients with KRAS mutations, Verastem Inc.  jumped 24.8% to $4.58. Setting a Prescription Drug User Fee Act action deadline of June 30, 2025, the FDA granted Priority Review, Verastem stated in a statement.GuruFocus has detected 5 Warning Signs with VSTM.Should approval be granted, the treatmentwhich is the first FDA-approved one expressly aimed at adults with recurrent KRAS mutant LGSOCwould Based on information from the Phase 2 RAMP 201 study, which showed notable response rates and tolerability for the combination treatment, the firm said, the application expands on data.With few therapeutic choices, LGSOC is an uncommon kind of ovarian cancer afflicting between 6,0008,000 women in the United States. Verastem underlined the ability of the treatment to solve this unmet medical need.Verastem h","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/verastem-shares-surge-over-24-153329366.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":"Verastem Shares Surge Over 24% on FDA Acceptance of Cancer Therapy Application","news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["VSTM","BK4139"],"gpt_icon":0},{"id":"2495240613","title":"Verastem Shares up 32% After FDA Grants Priority Review for Ovarian Cancer Combo Therapy","url":"https://stock-news.laohu8.com/highlight/detail?id=2495240613","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2495240613?lang=en_us&edition=fundamental","pubTime":"2024-12-31 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