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IO Biotech, Inc.

0.4801

+0.2725131.26%

Pre-market: 0.48020.0001+0.02%07:09 EST

Volume:473.91M

Turnover:190.44M

Market Cap:34.54M

PE:-0.36

High:0.5792

Open:0.2464

Low:0.2302

Close:0.2076

52wk High:2.79

52wk Low:0.2053

Shares:71.95M

Float Shares:31.16M

Volume Ratio:61.50

T/O Rate:1520.89%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-1.3356

EPS(LYR):-1.4494

ROE:-240.48%

ROA:-88.58%

PB:37.92

PE(LYR):-0.33

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Overview Company News Filings

IO Biotech Q3 Basic EPS USD -0.13

THOMSON REUTERS

Press Release: IO Biotech Reports Third Quarter 2025 Financial Results and Provides Business Highlights

IO Biotech Announces Participation in Upcoming Investor Conferences

IO Biotech Presents Pre-Clinical Data Highlighting the Potential of Additional Therapeutic Cancer Vaccine Candidates at the 2025 Annual Meeting of the Society for Immunotherapy of Cancer (SITC)

IO Biotech Is Maintained at Overweight by Piper Sandler

Piper Sandler Keeps Their Buy Rating on IO Biotech (IOBT)

IO Biotech reports expanded Cylembio results

IO Biotech Presents Phase 3 Results for Cylembio® plus KEYTRUDA® (pembrolizumab) in First-line Advanced Melanoma at ESMO 2025

IO Biotech Faces Setback as FDA Opposes Cylembio BLA Submission, Morgan Stanley Says

MT Newswires Live

Morgan Stanley Downgrades IO Biotech to Equalweight From Overweight, Cuts Price Target to $0.39 From $4

MT Newswires Live

Hold Rating for IO Biotech Amid Regulatory and Financial Challenges

TD Cowen downgrades IO Biotech (IOBT) to a Hold

IO Biotech Cut to Neutral From Buy by HC Wainwright & Co.

BUZZ-IO Biotech drops after FDA recommends another late-stage study for cancer vaccine

H.C. Wainwright downgrades IO Biotech (IOBT) to a Hold

H.C. Wainwright downgrades IO Biotech after FDA recommends another Phase 3 trial

IO Biotech Advised Against Filing Biologics License Application for Cylembio; Plans to Cut 50% of Workforce

MT Newswires Live

FDA Recommends Against IO Biotech’s Cylembio Application

IO Biotech to Reduce Headcount by 50% Amid Restructuring

BRIEF-IO Biotech Provides Update Following Pre-BLA Meeting with FDA

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The company’s shares closed yest...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/piper-sandler-keeps-their-buy-rating-on-io-biotech-iobt-blurbs?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate","earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/piper-sandler-keeps-their-buy-rating-on-io-biotech-iobt-blurbs?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"express","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["IOBT"],"gpt_icon":0},{"id":"2576375888","title":"IO Biotech reports expanded Cylembio 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Biotech Presents Phase 3 Results for Cylembio® plus KEYTRUDA® (pembrolizumab) in First-line Advanced Melanoma at ESMO 2025","url":"https://stock-news.laohu8.com/highlight/detail?id=2576838287","media":"GlobeNewswire","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2576838287?lang=en_us&edition=fundamental","pubTime":"2025-10-20 14:30","pubTimestamp":1760941800,"startTime":"0","endTime":"0","summary":"Cylembio plus pembrolizumab achieved a clinically relevant 19.4 months median progression free survival (mPFS) compared to 11.0 months mPFS with pembrolizumab alone; study narrowly missed progression 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Biotech Faces Setback as FDA Opposes Cylembio BLA Submission, Morgan Stanley Says","url":"https://stock-news.laohu8.com/highlight/detail?id=2571321067","media":"MT Newswires Live","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2571321067?lang=en_us&edition=fundamental","pubTime":"2025-09-30 23:06","pubTimestamp":1759244798,"startTime":"0","endTime":"0","summary":"IO Biotech (IOBT) faces increased near-term uncertainty after reporting that the US Food and Drug Administration recommended it not submit a biologics license application for cylembio in melanoma 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Stanley Downgrades IO Biotech to Equalweight From Overweight, Cuts Price Target to $0.39 From $4","url":"https://stock-news.laohu8.com/highlight/detail?id=2571657341","media":"MT Newswires Live","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2571657341?lang=en_us&edition=fundamental","pubTime":"2025-09-30 19:14","pubTimestamp":1759230889,"startTime":"0","endTime":"0","summary":"IO Biotech (IOBT) has an average rating of hold and mean price target of $6.13, according to analysts polled by FactSet.(MT Newswires covers equity, commodity and economic research from major banks an","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["IOBT"],"gpt_icon":0},{"id":"2571345086","title":"Hold Rating for IO Biotech Amid Regulatory and Financial Challenges","url":"https://stock-news.laohu8.com/highlight/detail?id=2571345086","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2571345086?lang=en_us&edition=fundamental","pubTime":"2025-09-30 18:16","pubTimestamp":1759227400,"startTime":"0","endTime":"0","summary":"In a report released yesterday, Michael Ulz from Morgan Stanley downgraded IO Biotech to a Hold, with a price target of $0.39. Michael Ulz has give...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/ratings/hold-rating-for-io-biotech-amid-regulatory-and-financial-challenges-ratings?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/ratings/hold-rating-for-io-biotech-amid-regulatory-and-financial-challenges-ratings?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["IOBT"],"gpt_icon":0},{"id":"2571363325","title":"TD Cowen downgrades IO Biotech (IOBT) to a Hold","url":"https://stock-news.laohu8.com/highlight/detail?id=2571363325","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2571363325?lang=en_us&edition=fundamental","pubTime":"2025-09-30 04:55","pubTimestamp":1759179313,"startTime":"0","endTime":"0","summary":"IO Biotech received a Hold rating and price target from TD Cowen analyst Yaron Werber today. The company’s shares closed today at $0.37. Werber cov...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/td-cowen-downgrades-io-biotech-iobt-to-a-hold-blurbs?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/td-cowen-downgrades-io-biotech-iobt-to-a-hold-blurbs?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["IOBT","COWN","TD"],"gpt_icon":0},{"id":"2571355426","title":"IO Biotech Cut to Neutral From Buy by HC Wainwright & Co.","url":"https://stock-news.laohu8.com/highlight/detail?id=2571355426","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2571355426?lang=en_us&edition=fundamental","pubTime":"2025-09-30 00:35","pubTimestamp":1759163700,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/IOBT/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  September 29, 2025 12:35 ET (16:35 GMT)","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IOBT"],"gpt_icon":0},{"id":"2571935567","title":"BUZZ-IO Biotech drops after FDA recommends another late-stage study for cancer vaccine","url":"https://stock-news.laohu8.com/highlight/detail?id=2571935567","media":"Reuters","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2571935567?lang=en_us&edition=fundamental","pubTime":"2025-09-30 00:25","pubTimestamp":1759163130,"startTime":"0","endTime":"0","summary":"BUZZ-IO Biotech drops after FDA recommends another late-stage study for cancer vaccine** Shares of biotech firm IO Biotech IOBT.O fall 77.8% to 35 cents ** Company says the FDA has recommended IO Biotech to not submit an application based on data from the late-stage study and will need a second one** In the late-stage study, the company was testing Cylembio in combination with Merck's MRK.N Keytruda for treating advanced skin cancer in which the results narrowly missed statistical significance** IOBT plans to continue the dialogue with FDA to align on the design of a potential new study for Cylembio** \"While this is not the outcome we had hoped for, we respect FDA's feedback and remain confident in the therapeutic potential of Cylembio,\" said CEO Mai-Britt Zocca** IOBT expects to incur a non-recurring charge of between $1 million and $1.5 million in Q3 2025 related to the restructuring, which includes around 50% reduction in full-time employees** H.C. Wainwright expects the launch of C","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250929:nL3N3VG14T:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IOBT","LU0106261372.USD","IE00B2B36J28.USD","LU0122379950.USD","IE000M9KFDE8.USD","LU0965509101.SGD","LU1093756325.SGD","MRK","LU0965509010.AUD","LU1934455863.HKD","IE00BLSP4239.USD","SG9999014567.USD","LU0861579265.USD","SG9999014542.SGD","LU1069347547.HKD","SG9999015341.SGD","LU1066051811.HKD","LU1093756168.USD","IE00BJJMRZ35.SGD","LU1037948897.HKD","LU1066051225.USD","SG9999014559.SGD","LU1061106388.HKD","LU2023250504.SGD","LU2361044949.HKD","IE00BLSP4452.SGD","LU1974910355.USD","LU0265550359.USD","LU2106854487.HKD","LU1035773651.USD","LU0234572021.USD","LU1037948541.HKD","LU0320765489.SGD","BK4516","LU0098860793.USD","LU1162221912.USD","LU2112291526.USD","SG9999013999.USD","SG9999001440.SGD","LU0965509283.SGD","BK4588","BK4139","LU0203347892.USD","LU1066053197.SGD","LU1699723380.USD","LU2468319806.SGD","SGXZ57979304.SGD","LU1989771016.USD","IE0002141913.USD","IE0009355771.USD"],"gpt_icon":0},{"id":"2571355547","title":"H.C. Wainwright downgrades IO Biotech (IOBT) to a Hold","url":"https://stock-news.laohu8.com/highlight/detail?id=2571355547","media":"TIPRANKS","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2571355547?lang=en_us&edition=fundamental","pubTime":"2025-09-30 00:05","pubTimestamp":1759161944,"startTime":"0","endTime":"0","summary":"IO Biotech received a Hold rating and price target from H.C. Wainwright analyst Emily Bodnar today. The company’s shares opened today at $0.36. Bod...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/h-c-wainwright-downgrades-io-biotech-iobt-to-a-hold-blurbs?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/h-c-wainwright-downgrades-io-biotech-iobt-to-a-hold-blurbs?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["IOBT"],"gpt_icon":0},{"id":"2571353974","title":"H.C. Wainwright downgrades IO Biotech after FDA recommends another Phase 3 trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2571353974","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2571353974?lang=en_us&edition=fundamental","pubTime":"2025-09-30 00:00","pubTimestamp":1759161631,"startTime":"0","endTime":"0","summary":"As previously reported, H.C. Wainwright downgraded IO Biotech (IOBT) to Neutral from Buy with no price target after the company gave an update from...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/h-c-wainwright-downgrades-io-biotech-after-fda-recommends-another-phase-3-trial-thefly?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/h-c-wainwright-downgrades-io-biotech-after-fda-recommends-another-phase-3-trial-thefly?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["IOBT"],"gpt_icon":0},{"id":"2571942338","title":"IO Biotech Advised Against Filing Biologics License Application for Cylembio; Plans to Cut 50% of Workforce","url":"https://stock-news.laohu8.com/highlight/detail?id=2571942338","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2571942338?lang=en_us&edition=fundamental","pubTime":"2025-09-29 20:00","pubTimestamp":1759147209,"startTime":"0","endTime":"0","summary":"IO Biotech  said Monday the US Food and Drug Administration recommended it not submit a Biologics License Application for Cylembio based on results from the IOB-013 clinical trial, which failed to meet statistical significance.The company said it will continue discussions with the FDA on the design of a potential new registrational study for Cylembio.IO Biotech said it is implementing a plan to conserve capital, including a workforce reduction of about 50% in full-time employees, and anticipates a non-recurring charge of $1 million to $1.5 million in Q3 2025. The company expects its current capital to fund operations into Q1 2026.IO Biotech shares were down more than 82% in recent Monday pre-bell activity.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["IOBT","BK4139"],"gpt_icon":0},{"id":"2571338283","title":"FDA Recommends Against IO Biotech’s Cylembio Application","url":"https://stock-news.laohu8.com/highlight/detail?id=2571338283","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2571338283?lang=en_us&edition=fundamental","pubTime":"2025-09-29 19:50","pubTimestamp":1759146616,"startTime":"0","endTime":"0","summary":"IO Biotech ( ($IOBT) ) has shared an announcement. On September 25, 2025, IO Biotech‘s Board of Directors approved a restructuring plan to conserve...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/company-announcements/fda-recommends-against-io-biotechs-cylembio-application?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/company-announcements/fda-recommends-against-io-biotechs-cylembio-application?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["IOBT","BK4139"],"gpt_icon":0},{"id":"2571059380","title":"IO Biotech to Reduce Headcount by 50% Amid Restructuring","url":"https://stock-news.laohu8.com/highlight/detail?id=2571059380","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2571059380?lang=en_us&edition=fundamental","pubTime":"2025-09-29 19:46","pubTimestamp":1759146360,"startTime":"0","endTime":"0","summary":"IO Biotech will lay off approximately half of its employees, or around 40 workers, in a restructuring aimed at conserving capital while the company works to complete current studies.The restructuring comes after the biopharmaceutical company said on Monday that the Food and Drug Administration recommended it not to submit a biologics license application for its cancer vaccine, Cylembio. The recommendation followed results from a recent trial that the company said narrowly missed statistical significance.Shares tumbled 75% to 39 cents in premarket trading.IO Biotech said it will continue pursuing a pathway to regulatory approval for Cylembio while working to complete current studies. The company currently has capital to run its operations into next year's first quarter, it added.The company said it expects its restructuring to reduce its continuing expense structure and anticipates a non-recurring charge of between $1 million and $1.5 million in the current quarter stemming from the res","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","IOBT"],"gpt_icon":0},{"id":"2571238757","title":"BRIEF-IO Biotech Provides Update Following Pre-BLA Meeting with FDA","url":"https://stock-news.laohu8.com/highlight/detail?id=2571238757","media":"Reuters","labels":["event"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2571238757?lang=en_us&edition=fundamental","pubTime":"2025-09-29 19:11","pubTimestamp":1759144286,"startTime":"0","endTime":"0","summary":"BRIEF-IO Biotech Provides Update Following Pre-BLA Meeting with FDASept 29 (Reuters) - IO Biotech Inc IOBT.O:IO BIOTECH PROVIDES UPDATE FOLLOWING PRE-BLA MEETING WITH FDAIO BIOTECH INC - FDA RECOMMEND","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250929:nTUA4ZDH4T:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"event","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","IOBT"],"gpt_icon":1}],"pageSize":20,"totalPage":4,"pageCount":2,"totalSize":64,"code":"91000000","status":"200"}]}}