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Harmony Biosciences Holdings, Inc.

26.90

+0.36001.36%

Volume:636.23K

Turnover:17.12M

Market Cap:1.55B

PE:9.93

High:27.13

Open:26.59

Low:26.34

Close:26.54

52wk High:40.87

52wk Low:25.52

Shares:57.60M

Float Shares:44.56M

Volume Ratio:0.85

T/O Rate:1.43%

Dividend:- -

Dividend Rate:- -

EPS(TTM):2.71

EPS(LYR):2.71

ROE:20.75%

ROA:11.48%

PB:1.78

PE(LYR):9.93

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Overview Company News Filings

Harmony Biosciences Shares Down 9% as Genetic Disorder Drug Fails Late-Stage Trial

THOMSON REUTERS

Harmony Biosciences Stock (HRMY) Sinks on Failed Phase 3 Study

BUZZ-Harmony falls as genetic disorder drug fails late-stage trial

Harmony Biosciences Shares Drop After Study Misses Primary Endpoint

Harmony Biosciences Shares Down 8% Premarket After Co's Genetic Disorder Drug Fails to Meet Main Goal in Late-Stage Trial

THOMSON REUTERS

Harmony Biosciences' genetic disorder drug fails to meet main goal in late-stage trial

Harmony Biosciences Announces Topline Results from Phase 3 RECONNECT Study of ZYN002 in Fragile X Syndrome

Harmony Biosciences Holdings Inc - Reconnect Study Fails to Meet Primary Endpoint

THOMSON REUTERS

Harmony Biosciences Provides Update From Its Phase 3 Reconnect Study of Zyn002 in Fragile X Syndrome

THOMSON REUTERS

11 fast-growing small-cap stocks that could get a boost from the Fed's next move

Harmony Biosciences Holdings (HRMY) Gets a Buy from UBS

Harmony Biosciences Holdings (HRMY) Reports Impressive Earnings Growth

Simply Wall St.

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(HRMY) Sinks on Failed Phase 3 Study","url":"https://stock-news.laohu8.com/highlight/detail?id=2569701152","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2569701152?lang=en_us&edition=fundamental","pubTime":"2025-09-24 20:27","pubTimestamp":1758716879,"startTime":"0","endTime":"0","summary":"Harmony Biosciences stock fell hard on Wednesday after the company posted poor Phase 3 clinical trial 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trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2569070947","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2569070947?lang=en_us&edition=fundamental","pubTime":"2025-09-24 20:21","pubTimestamp":1758716512,"startTime":"0","endTime":"0","summary":"BUZZ-Harmony falls as genetic disorder drug fails late-stage trial** Shares of drug developer Harmony Biosciences HRMY.O fall 6.6% to $29.94 premarket** Co says its experimental drug, ZYN002, did not meet the main goal in a late-stage trial testing it in patients with Fragile X syndrome ** Fragile X syndrome  is a genetic disorder and one of the most common causes of inherited intellectual disability** HRMY says the drug did not meet the main goal of improvement in social avoidance primarily due to a higher than expected placebo response rate** Up to last close, stock down 6.8% YTD  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pharmaceutical company's late-stage trial of proposed treatment for rare genetic disorder Fragile X syndrome failed to meet its main goal.Harmony on Wednesday said topline results from its Phase 3 registrational clinical trial of ZYN002 in Fragile X syndrome didn't meet the primary endpoint of improvement in social avoidance primarily due to a higher than expected placebo response rate.In premarket trading, the shares were 7.1% lower after ending the previous session at $32.07, down 15% over the last 12 months.The study was a randomized, double-blind, placebo-controlled, multiple-center study to assess the efficacy and safety of ZYN002, a pharmaceutically manufactured cannabidiol administered as a transdermal gel to patients ages three to under 30 years old.Kumar Budur, the company's chief medical and scientific officer, said that although the study didn't achieve its primary endpoint, the findings provide valuable insights into Fragile X 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20:07","pubTimestamp":1758715639,"startTime":"0","endTime":"0","summary":"Harmony Biosciences' genetic disorder drug fails to meet main goal in late-stage trialSept 24  - Harmony Biosciences HRMY.O said on Wednesday its experimental drug for a type of rare genetic disorder failed to meet the main goal in a late-stage trial.  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The randomized, double-blind, placebo-controlled, multi-center trial did not meet its primary endpoint of improvement in social avoidance, which the company attributed primarily to a higher than expected placebo response rate. The results from the study have been presented. Harmony Biosciences stated that it will conduct a comprehensive analysis of the full dataset to further understand the findings and remains committed to the Fragile X community. The company also reaffirmed plans to initiate Phase 3 trials for pitolisant HD in narcolepsy and idiopathic hypersomnia in the fourth quarter of this year.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. 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Investors are anticipating that the Federal Open Market Committee will cut the federal-funds rate on Sept. 17.Small-cap stocks have lagged behind large-cap stocks this year and over the past five years - but the story is a bit more interesting than that, while the anticipated resumption of Federal Reserve interest-rate cuts might serve as a catalyst for shares of small-cap U.S. companies.Lower short-term rates could be especially helpful for small-cap U.S. companies because of their focus on domestic sales and because a lower federal-funds rate might make for reduced borrowing costs.In an email on Monday, Jay Woods, chief global strategist at Freedom Capital Markets in New York, wrote that investors might see \"excessive volatility\" following Federal Reserve Chair Jerome Powell's press conference Wednesday afternoon, following the Federal Open Market Committee's two-day policy meeting. 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Despite these positive updates, which might have typically supported a stronger upward trend, the company's share price remained flat over the last quarter, moving by only 0.36%. 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