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Precision Biosciences Inc

4.75

-0.0495-1.03%

Volume:24.50K

Turnover:118.00K

Market Cap:52.67M

PE:-1.70

High:4.92

Open:4.71

Low:4.70

Close:4.80

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Overview Company News Filings

Precision BioSciences Presents Preclinical Safety and Efficacy Data Supporting Repeat Dosing of PBGENE-HBV With a Goal of Curing Chronic Hepatitis B at the Global Hepatitis Summit 2025

Precision Biosciences Price Target Maintained With a $60.00/Share by HC Wainwright & Co.

Precision BioSciences presents preclinical data from PBGENE-DMD program

Precision BioSciences Presents Preclinical Efficacy and Durability Data on PBGENE-DMD for the Treatment of Duchenne Muscular Dystrophy (DMD) at the 2025 Muscular Dystrophy Association (MDA) Clinical & Scientific Conference

Precision Says its Investigational New Drug Application for Hepatitis B Treatment Gets US FDA's Clearance

MT Newswires Live

Precision BioSciences Announces Clearance of Investigational New Drug Application by the U.S. FDA for First-in-Class PBGENE-HBV Designed to Eliminate Root Cause of Chronic Hepatitis B

Calendar of U.S. Earnings Expected in the Week Ahead

Precision BioSciences Announces Oral Presentation at the 2025 Muscular Dystrophy Association (MDA) Clinical & Scientific Conference

Precision BioSciences Touts Encouraging Initial Safety And Antiviral Activity Of Hepatitis B Treatment Candidate

Precision Biosciences Price Target Maintained With a $60.00/Share by HC Wainwright & Co.

BRIEF-Precision Biosciences Announces Initial Safety And Antiviral Activity Of Pbgene-Hbv

Precision BioSciences Announces Initial Safety and Antiviral Activity of PBGENE-HBV in the ELIMINATE-B Clinical Trial

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In non-human primates , repeated administration of PBGENE-HBV was safe and well tolerated, with no systemic accumulation of PBGENE-HBV drug product. Furthermore, PBGENE-HBV was not distributed to germ cells at any of the analyzed timepoints, supporting the conclusion that there is no risk of heritable genome edits. Additionally, the Company conducted extensive nuclease specif","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/precision-biosciences-presents-preclinical-safety-110100540.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["SMMF","DTIL","GHS","BK4139","BK4211"],"gpt_icon":0},{"id":"2520152238","title":"Precision Biosciences Price Target Maintained With a $60.00/Share by HC Wainwright & Co.","url":"https://stock-news.laohu8.com/highlight/detail?id=2520152238","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2520152238?lang=en_us&edition=fundamental","pubTime":"2025-03-20 00:37","pubTimestamp":1742402220,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/DTIL/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  March 19, 2025 12:37 ET (16:37 GMT)","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["DTIL"],"gpt_icon":0},{"id":"2520290265","title":"Precision BioSciences presents preclinical data from PBGENE-DMD program","url":"https://stock-news.laohu8.com/highlight/detail?id=2520290265","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2520290265?lang=en_us&edition=fundamental","pubTime":"2025-03-19 19:15","pubTimestamp":1742382911,"startTime":"0","endTime":"0","summary":"Precision BioSciences (DTIL) announced the presentation of preclinical data for its PBGENE-DMD development program for the treatment of Duchenne mu...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/precision-biosciences-presents-preclinical-data-from-pbgene-dmd-program?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/precision-biosciences-presents-preclinical-data-from-pbgene-dmd-program?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","DTIL"],"gpt_icon":0},{"id":"2520118820","title":"Precision BioSciences Presents Preclinical Efficacy and Durability Data on PBGENE-DMD for the Treatment of Duchenne Muscular Dystrophy (DMD) at the 2025 Muscular Dystrophy Association (MDA) Clinical & Scientific Conference","url":"https://stock-news.laohu8.com/highlight/detail?id=2520118820","media":"Business Wire","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2520118820?lang=en_us&edition=fundamental","pubTime":"2025-03-19 19:01","pubTimestamp":1742382060,"startTime":"0","endTime":"0","summary":"- Potential first-in-class gene editing approach designed for dystrophin gene correction leading the body to produce a functional dystrophin protein applicable for majority of DMD patients . - PBGENE-DMD restored dystrophin protein expression and significantly improved muscle function over time while demonstrating long-term durability in an in vivo DMD disease model –。- PBGENE-DMD dystrophin gene correction observed in muscle satellite stem cells suggesting potential for permanent functional benefit –。Title: ARCUS-Mediated Excision of Exons 45-55 Leads to Functional Del45-55 Dystrophin and Restoration of Skeletal Muscle-Function for the Treatment of DMDOral Presentation Date and Time: Wednesday, March 19, 2025, 8:00 AM CTPoster Number: O159. In preclinical data to be presented today, PBGENE-DMD demonstrated significant functional improvement in a humanized DMD mouse model by employing two complementary ARCUS nucleases delivered in a single AAV to excise exons 45-55 of the dystrophin ge","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/precision-biosciences-presents-preclinical-efficacy-110100578.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4139","MDA","DTIL","MFO"],"gpt_icon":0},{"id":"2520281735","title":"Precision Says its Investigational New Drug Application for Hepatitis B Treatment Gets US FDA's Clearance","url":"https://stock-news.laohu8.com/highlight/detail?id=2520281735","media":"MT Newswires Live","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2520281735?lang=en_us&edition=fundamental","pubTime":"2025-03-17 20:22","pubTimestamp":1742214156,"startTime":"0","endTime":"0","summary":"Precision BioSciences  said Monday its investigational new drug application for PBGENE-HBV in vivo gene editing program has received the US Food and Drug Administration's clearance to treat chronic hepatitis B.The company is in final stages of US site activation to start enrolling participants in its Eliminate-B study in the country and will soon initiate phase 1 clinical activities at the Liver Center at Massachusetts General Hospital, Precision added.The trial is already enrolling patients in Moldova, Hong Kong, and New Zealand, the company said, adding that it intends to expand the trial in the UK.Shares of the company were up more than 7% in recent Monday premarket activity.Price: 5.40, Change: +0.36, Percent Change: +7.14","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK4139","DTIL"],"gpt_icon":0},{"id":"2520284855","title":"Precision BioSciences Announces Clearance of Investigational New Drug Application by the U.S. FDA for First-in-Class PBGENE-HBV Designed to Eliminate Root Cause of Chronic Hepatitis B","url":"https://stock-news.laohu8.com/highlight/detail?id=2520284855","media":"Business Wire","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2520284855?lang=en_us&edition=fundamental","pubTime":"2025-03-17 19:01","pubTimestamp":1742209260,"startTime":"0","endTime":"0","summary":"- PBGENE-HBV is the first-ever investigational in vivo gene editing therapy cleared to enter clinical trials for the treatment of chronic hepatitis B in the United States  –。- IND clearance represents a significant regulatory milestone for PBGENE-HBV –。- Company to expand its Phase 1 ELIMINATE-B study to the U.S., joining world-class clinical sites in Moldova, Hong Kong, and New Zealand where strong clinical execution is currently underway –。\"IND clearance to expand the ELIMINATE-B trial for chronic hepatitis B is a first for the gene editing space. This marks the advancement of potentially curative gene editing modalities into major markets for diseases where enormous global disease burden and lack of curative options have unfortunately become the norm,\" said Michael Amoroso, President and Chief Executive Officer of Precision BioSciences. \"With four regulatory approvals in four months, this clearance validates our parallel global development strategy backed by our robust pre-clinical ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/precision-biosciences-announces-clearance-investigational-110100771.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4551","DTIL","BK4139","BK4505","ROOT","BK4107"],"gpt_icon":0},{"id":"2519876572","title":"Calendar of U.S. Earnings Expected in the Week Ahead","url":"https://stock-news.laohu8.com/highlight/detail?id=2519876572","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2519876572?lang=en_us&edition=fundamental","pubTime":"2025-03-14 18:00","pubTimestamp":1741946400,"startTime":"0","endTime":"0","summary":"Major companies tentatively scheduled to report quarterly earnings in the week ahead, with earnings estimates provided by FactSet Research Systems Inc.·Bitcoin Depot Inc.                               4Q       .02   8:05 AM. ·IHS Hldg Ltd.                                    4Q       .01   6:00 AM","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LPRO","LVTX","ACN","NKTX","LXEO","ABSI","FDX","DTIL","RLYB","PRSO","AEVA","PL","LE","MRC","LAR","INKT","HROW","STNE","GANX","JILL","AUTL","AMPX","HTHT","OSS","TME","GOGO","LQDA","MBRX","CNTX","DTI","FDS","ANRO","DRI","KOPN","NRXP","IFRX","TYRA","CAL","MGNX","INSE","SPRY","IDN","CAPR","RANI","HYPR","GIS","ERAS"],"gpt_icon":1},{"id":"2513069728","title":"Precision BioSciences Announces Oral Presentation at the 2025 Muscular Dystrophy Association (MDA) Clinical & Scientific Conference","url":"https://stock-news.laohu8.com/highlight/detail?id=2513069728","media":"Business Wire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2513069728?lang=en_us&edition=fundamental","pubTime":"2025-02-24 20:01","pubTimestamp":1740398460,"startTime":"0","endTime":"0","summary":"DURHAM, N.C., February 24, 2025----Precision BioSciences, Inc. , a clinical stage gene editing company utilizing its novel proprietary ARCUS platform to develop in vivo gene editing therapies, including gene elimination, gene insertion, and gene excision programs, today announced that the company will present preclinical data from the PBGENE-DMD program for the treatment of Duchenne muscular dystrophy  during an oral presentation at the 2025 Muscular Dystrophy Association  Clinical & Scientific Conference being held March 16-19, 2025.Title: ARCUS-Mediated Excision of Exons 45-55 Leads to Functional Del45-55 Dystrophin and Restoration of Skeletal Muscle-Function for the Treatment of DMDDate and Time: Wednesday, March 19, 2025, 8:00 AM CT. The abstract is now publicly accessible through the MDA website here.The ARCUS platform is being used to develop in vivo gene editing therapies for sophisticated gene edits, including gene insertion , elimination , and excision .","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/precision-biosciences-announces-oral-presentation-120100398.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["MDA","BK4139","DTIL"],"gpt_icon":0},{"id":"2512583436","title":"Precision BioSciences Touts Encouraging Initial Safety And Antiviral Activity Of Hepatitis B Treatment Candidate","url":"https://stock-news.laohu8.com/highlight/detail?id=2512583436","media":"Benzinga","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2512583436?lang=en_us&edition=fundamental","pubTime":"2025-02-20 03:27","pubTimestamp":1739993244,"startTime":"0","endTime":"0","summary":"On Wednesday, Precision BioSciences, Inc.  revealed initial results from the first administration of PBGENE-HBV in cohort 1, the lowest dose level of the ELIMINATE-B trial.The ELIMINATE-B trial is designed to investigate PBGENE-HBV at multiple ascending dose levels with three dose administrations per dose level in chronic Hepatitis B patients who are HBeAg-negative.Also Read: Precision BioSciences’ Gene Editing Platform Has Differentiated Mechanism, And Is Potentially Competitive: Analyst. PBGENE-HBV, which comprises an ARCUS-encoding mRNA encapsulated in a lipid nanoparticle , was safe and well tolerated in all three cohort 1 participants after the first administration of a 0.2 mg/kg dose. The planned dosing schedule in ELIMINATE-B allows for two additional administrations at this dose level while simultaneously investigating the next higher dose level.In addition to safety, PBGENE-HBV demonstrated a substantial reduction in Hepatitis B surface antigen  in two of the three participant","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/precision-biosciences-touts-encouraging-initial-192724128.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["DTIL","BK4139"],"gpt_icon":0},{"id":"2512548239","title":"Precision Biosciences Price Target Maintained With a $60.00/Share by HC Wainwright & Co.","url":"https://stock-news.laohu8.com/highlight/detail?id=2512548239","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2512548239?lang=en_us&edition=fundamental","pubTime":"2025-02-20 00:43","pubTimestamp":1739983380,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/DTIL/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  February 19, 2025 11:43 ET (16:43 GMT)","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["DTIL"],"gpt_icon":0},{"id":"2512052121","title":"BRIEF-Precision Biosciences Announces Initial Safety And Antiviral Activity Of Pbgene-Hbv","url":"https://stock-news.laohu8.com/highlight/detail?id=2512052121","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2512052121?lang=en_us&edition=fundamental","pubTime":"2025-02-19 20:04","pubTimestamp":1739966667,"startTime":"0","endTime":"0","summary":"BRIEF-Precision Biosciences Announces Initial Safety And Antiviral Activity Of Pbgene-HbvFeb 19 (Reuters) - Precision BioSciences Inc DTIL.O:PRECISION BIOSCIENCES ANNOUNCES INITIAL SAFETY AND ANTIVIRA","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250219:nTUA4DVX3B:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["DTIL","BK4139"],"gpt_icon":0},{"id":"2512433106","title":"Precision BioSciences Announces Initial Safety and Antiviral Activity of PBGENE-HBV in the ELIMINATE-B Clinical Trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2512433106","media":"Business Wire","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2512433106?lang=en_us&edition=fundamental","pubTime":"2025-02-19 20:01","pubTimestamp":1739966460,"startTime":"0","endTime":"0","summary":"ELIMINATE-B Phase 1 dose finding study for chronic Hepatitis B executing on schedule with completion of first dose administration for cohort 1 . PBGENE-HBV, the first LNP gene editing technology studied for Hepatitis B, was safe and well tolerated. PBGENE-HBV demonstrated substantial antiviral activity measured by reduction of Hepatitis B surface antigen  after one administration at the lowest dose level. First clinical proof-of-concept in chronic Hepatitis B for a unique editing modality designed to directly eliminate and inactivate the root cause of Hepatitis B virus from covalently closed circular DNA  and integrated DNA. These PBGENE-HBV data mark the second clinical validation for ARCUS in vivo gene editing in 2025. In addition to safety, PBGENE-HBV demonstrated a substantial reduction in Hepatitis B surface antigen  in two of the three participants following the first administration at dose level 1. 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