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Charles River Laboratories

154.48

-2.2200-1.42%

Post-market: 154.480.00000.00%16:51 EDT

Volume:493.64K

Turnover:76.44M

Market Cap:7.59B

PE:-249.91

High:158.18

Open:158.01

Low:153.31

Close:156.70

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Overview Company News Filings

Will Charles River (CRL) Beat Estimates Again in Its Next Earnings Report?

Bausch + Lomb (BLCO) Moves 13.9% Higher: Will This Strength Last?

Charles River price target lowered to $145 from $160 at Barclays

Charles River Labs Is Maintained at Neutral by Mizuho

Goldman Sachs Adjusts Charles River Laboratories International PT to $150 From $170, Maintains Neutral Rating

MT Newswires Live

Outlook Therapeutics® Announces Acceptance of Biologics License Application by U.S. FDA for ONS-5010 as a Treatment for Wet AMD

Charles River Laboratories International Inc. Stock Underperforms Monday When Compared To Competitors

Charles River Laboratories International Inc. Stock Underperforms Thursday When Compared To Competitors

Aldeyra down 75% after receiving CRL from FDA for reproxalap

Charles River Laboratories International Inc. Stock Falls 3.2%, Underperforms Competitors

BUZZ - S&P 500 top and bottom performing stocks at about 03:30 p.m. EDT

Baird Adjusts Charles River Laboratories International Price Target to $155 From $173, Maintains Neutral Rating

MT Newswires Live

Charles River & Valo Health's Logica Identifies New Lupus Drug Candidate

FDA Issues Complete Response Letter for Etripamil for PSVT

Charles River Laboratories International Inc. Stock Underperforms Wednesday When Compared To Competitors

Charles River Laboratories International Inc. Stock Sheds 3.4%, Underperforms Competitors

Charles River, Valo Health Identify First Lupus Treatment Candidate Using Logica AI Platform

MT Newswires Live

Charles River and Valo Health Identify Potential Therapeutic for Lupus Using Logica

THOMSON REUTERS

Charles River and Valo Health Identify a Potential Therapeutic for Lupus Using Logica®, an AI-Powered Drug Discovery Platform

ABEO: Countdown to PDUFA Date of April 29, 2025…

Zacks Small Cap Research

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The average surprise for the last two quarters was 6.49%.For the last reported quarter, Charles River came out with earnings of $2.66 per share versus the Zacks Consensus Estimate of $2.50 per share, representing a surprise of 6.40%. For the previous quarter, the company was expected to post earnings of $2.43 per share and it actually produced earnings of $2.59 per share, delivering a surprise of 6.58%.Want the latest recommendations from Zacks Investment Research?Today, you can download 7 Best Stocks for the Next 30 Days. 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The jump came on an impressive volume with a higher-than-average number of shares changing hands in the session. This compares to the stock's 29.2% loss over the past four weeks.Bausch + Lomb stock surged amid a broader market rebound following the Trump administration’s announcement of a temporary halt on reciprocal tariffs for most countries. The market is also upbeat about the company’s surrounding its impending first-quarter 2025 financial results, which is slated to release on April 30 before the opening bell.This company is expected to post quarterly earnings of $0.06 per share in its upcoming report, which represents a year-over-year change of -14.3%. Revenues are expected to be $1.15 billion, up 4.4% from the year-ago quarter.Bausch + Lomb Corporation  : Free Stock Analysis Report. Charles River Laboratories International, Inc.  : Free Stock Analysis Report. This article originally published on Zac","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/bausch-lomb-blco-moves-13-130500986.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4121","BK4588","CRL","BK4585","BK4007","BK4530","BLCO","BHC","BK4198","LU0390134368.USD"],"gpt_icon":0},{"id":"2526216558","title":"Charles River price target lowered to $145 from $160 at Barclays","url":"https://stock-news.laohu8.com/highlight/detail?id=2526216558","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2526216558?lang=en_us&edition=fundamental","pubTime":"2025-04-10 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Mizuho","url":"https://stock-news.laohu8.com/highlight/detail?id=2526436802","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2526436802?lang=en_us&edition=fundamental","pubTime":"2025-04-09 20:03","pubTimestamp":1744200180,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/CRL/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  April 09, 2025 08:03 ET (12:03 GMT)","market":"other","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["CRL","MFG"],"gpt_icon":0},{"id":"2526843066","title":"Goldman Sachs Adjusts Charles River Laboratories International PT to $150 From $170, Maintains Neutral Rating","url":"https://stock-news.laohu8.com/highlight/detail?id=2526843066","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2526843066?lang=en_us&edition=fundamental","pubTime":"2025-04-09 00:46","pubTimestamp":1744130770,"startTime":"0","endTime":"0","summary":"Charles River Laboratories International (CRL) has an average rating of Hold and mean price target of $172.33, according to analysts polled by FactSet.(MT Newswires covers equity, commodity and econom","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["CRL","PT"],"gpt_icon":0},{"id":"2525289408","title":"Outlook Therapeutics® Announces Acceptance of Biologics License Application by U.S. FDA for ONS-5010 as a Treatment for Wet AMD","url":"https://stock-news.laohu8.com/highlight/detail?id=2525289408","media":"GlobeNewswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2525289408?lang=en_us&edition=fundamental","pubTime":"2025-04-08 20:45","pubTimestamp":1744116300,"startTime":"0","endTime":"0","summary":"Prescription Drug User Fee Act (PDUFA) goal date of August 27, 2025Prescription Drug User Fee Act (PDUFA) goal date of August 27, 2025 ISELIN, N.J., April  08, 2025  (GLOBE NEWSWIRE) -- Outlook 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River Laboratories International Inc. Stock Underperforms Monday When Compared To Competitors","url":"https://stock-news.laohu8.com/highlight/detail?id=2525234074","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2525234074?lang=en_us&edition=fundamental","pubTime":"2025-04-08 05:21","pubTimestamp":1744060860,"startTime":"0","endTime":"0","summary":"This article was automatically generated by MarketWatch using technology from Automated Insights.Shares of Charles River Laboratories International Inc.  slipped 2.07% to $134.07 Monday, on what proved to be an all-around grim trading session for the stock market, with the S&P 500 Index  falling 0.23% to 5,062.25 and Dow Jones Industrial Average  falling 0.91% to 37,965.60.This was the stock's third consecutive day of losses.Charles River Laboratories International Inc. closed 48.15% short of its 52-week high of $258.56, which the company reached on April 9th.The stock underperformed when compared to some of its competitors Monday, as Labcorp Holdings Inc.  fell 0.67% to $223.50, Alnylam Pharmaceuticals Inc.  fell 1.18% to $232.95, and Bio-Techne Corp.  rose 1.14% to $52.31.Trading volume  eclipsed its 50-day average volume of 1.2 M.Data source: Dow Jones Market Data, FactSet. Data compiled April 7, 2025.This content was created by MarketWatch, which is operated by Dow Jones & Co. Mark","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["CRL"],"gpt_icon":0},{"id":"2524021184","title":"Charles River Laboratories International Inc. Stock Underperforms Thursday When Compared To Competitors","url":"https://stock-news.laohu8.com/highlight/detail?id=2524021184","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2524021184?lang=en_us&edition=fundamental","pubTime":"2025-04-04 05:19","pubTimestamp":1743715140,"startTime":"0","endTime":"0","summary":"This article was automatically generated by MarketWatch using technology from Automated Insights.Shares of Charles River Laboratories International Inc.  slipped 5.56% to $140.98 Thursday, on what proved to be an all-around dismal trading session for the stock market, with the S&P 500 Index  falling 4.84% to 5,396.52 and Dow Jones Industrial Average  falling 3.98% to 40,545.93.Charles River Laboratories International Inc. closed 46.74% short of its 52-week high of $264.71, which the company reached on April 4th.The stock demonstrated a mixed performance when compared to some of its competitors Thursday, as Labcorp Holdings Inc.  fell 1.23% to $233.46, Alnylam Pharmaceuticals Inc.  fell 1.75% to $262.16, and Bio-Techne Corp.  fell 6.03% to $54.86.Data source: Dow Jones Market Data, FactSet. Data compiled April 3, 2025.This content was created by MarketWatch, which is operated by Dow Jones & Co. MarketWatch is published independently from Dow Jones Newswires and The Wall Street Journal.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["CRL"],"gpt_icon":0},{"id":"2524254736","title":"Aldeyra down 75% after receiving CRL from FDA for reproxalap","url":"https://stock-news.laohu8.com/highlight/detail?id=2524254736","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2524254736?lang=en_us&edition=fundamental","pubTime":"2025-04-03 20:50","pubTimestamp":1743684611,"startTime":"0","endTime":"0","summary":"After resuming pre-market trading, shares of Aldeyra (ALDX) are down $4.00, or 75%, to $1.32. Published first on TheFly – the ultimate source for r...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/aldeyra-down-75-after-receiving-crl-from-fda-for-reproxalap?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/aldeyra-down-75-after-receiving-crl-from-fda-for-reproxalap?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["ALDX","BK4530","BK4121","LU0390134368.USD","BK4585","BK4588","BK4139","CRL"],"gpt_icon":0},{"id":"2524997732","title":"Charles River Laboratories International Inc. Stock Falls 3.2%, Underperforms Competitors","url":"https://stock-news.laohu8.com/highlight/detail?id=2524997732","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2524997732?lang=en_us&edition=fundamental","pubTime":"2025-04-01 04:35","pubTimestamp":1743453300,"startTime":"0","endTime":"0","summary":"This article was automatically generated by Dow Jones using technology from Automated Insights.Shares of Charles River Laboratories International Inc. slipped 3.2% to $150.52 on what proved to be an all-around positive trading session for the stock market, with the S&P 500 Index rising 0.6% to 5,611.85 and the Dow Jones Industrial Average rising 1.0% to 42,001.76.This was the stock's sixth consecutive day of losses.Charles River Laboratories International Inc. closed 44.9% below its 52-week high of $273.32, which the company achieved on April 1st.The stock underperformed when compared to some of its competitors, as Labcorp Holdings Inc. rose 1.2% to $232.74, Alnylam Pharmaceuticals Inc. rose 0.6% to $270.02, and Bio-Techne Corp. fell 0.17% to $58.63.Trading volume totaled 1.4 million, compared to the 50-day average of 1.2 million.","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["CRL"],"gpt_icon":0},{"id":"2524971817","title":"BUZZ - S&P 500 top and bottom performing stocks at about 03:30 p.m. EDT","url":"https://stock-news.laohu8.com/highlight/detail?id=2524971817","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2524971817?lang=en_us&edition=fundamental","pubTime":"2025-04-01 03:30","pubTimestamp":1743449417,"startTime":"0","endTime":"0","summary":"BUZZ - S&P 500 top and bottom performing stocks at about 03:30 p.m. EDTS&P 500 .SPXTop PerformersPercent ChangeDiscover Financial Services DFS.N+7.2%Live Nation Entertainment Inc LYV.N+4.2%American International Group Inc AIG.N+4.2%Ford Motor Co F.N+3.2%Fox Corp FOX.OQ+3.1%Bottom PerformersPercent ChangeModerna Inc MRNA.OQ-8.0%Lululemon Athletica Inc LULU.OQ-4.0%Charles River Laboratories International Inc CRL.N-3.5%Palantir Technologies Inc PLTR.OQ-3.0%Texas Pacific Land Corp TPL.N-2.7%As of 03:30 p.m., the S&P 500 .SPX gained 14.41 points, or 0.26%, to 5,595.35 and had posted 26 new 52-week highs and 45 new lows.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250331:nL5N3QE1K7:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4125","CRL","BK4588","BK4023","LU0477156953.USD","AIG","BK4213","FOXA","LU1791807156.HKD","FOX","LU1201861165.SGD","BK4551","BK4574","LULU","BK4532","IE00B19Z3B42.SGD","BK4121","LU0106831901.USD","BK4166","PLTR","LU0130102774.USD","BK4548","BK4613","LU1201861249.SGD","BK4543","BK4534","LU0648001328.SGD","BK4566","BK4117","LU0162691827.USD","IE00B7SZLL34.SGD","LU1668664300.SGD","F","LU0648000940.SGD","BK4108","BK4099","DFS","IE00B19Z3581.USD","LU1861559042.SGD","LU0072461881.USD","BK4585","TPL","LU0130518102.USD","LYV","LU1861220207.SGD","LU1861558580.USD","LU2065169927.USD","IE0002270589.USD","LU1496350502.SGD","MRNA"],"gpt_icon":1},{"id":"2523280689","title":"Baird Adjusts Charles River Laboratories International Price Target to $155 From $173, Maintains Neutral Rating","url":"https://stock-news.laohu8.com/highlight/detail?id=2523280689","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2523280689?lang=en_us&edition=fundamental","pubTime":"2025-03-31 22:27","pubTimestamp":1743431275,"startTime":"0","endTime":"0","summary":"Charles River Laboratories International (CRL) has an average rating of Hold and mean price target of $173.67, according to analysts polled by FactSet.(MT Newswires covers equity, commodity and econom","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["CRL"],"gpt_icon":0},{"id":"2523926560","title":"Charles River & Valo Health's Logica Identifies New Lupus Drug Candidate","url":"https://stock-news.laohu8.com/highlight/detail?id=2523926560","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2523926560?lang=en_us&edition=fundamental","pubTime":"2025-03-31 21:20","pubTimestamp":1743427200,"startTime":"0","endTime":"0","summary":"Charles River Laboratories International, Inc.CRL and Valo Health, Inc. recently announced an advanced product candidate for the treatment of different forms of lupus and other autoimmune indications with significant unmet needs. The discovery marks the first using Logica, an artificial intelligence -powered drug development solution that translates biological insights into optimized preclinical assets.Alongside Valo Health and Flagship Pioneering’s in-house drug development unit, Pioneering Medicines, Charles River looks forward to further leveraging the power of Logica to advance this program into lead optimization.Importance of Charles River and Valo’s Combined Offering. Logica, the result of a strategic collaboration between Charles River and Valo Health, is the industry’s first computation-powered, unified target-to-candidate offering. The platform leverages the integration of Valo Health’s AI-powered Opal Computational Platform and Charles River’s leading expertise in drug discov","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/charles-river-valo-healths-logica-132000618.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["CRL","BK4530","LU1914381329.SGD","LU2298321311.HKD","BIO","BK4535","LU0957791311.USD","BK4566","LU1670628061.USD","LU2041044095.USD","LU2125909247.SGD","LU2211814178.USD","BK4533","LU1712237335.SGD","IE00BFTCPJ56.SGD","SLE","BK4077","IE00B2B36J28.USD","LU1989771016.USD","LU2764262908.HKD","IE00BJJMRZ35.SGD","LU1983299246.USD","TMO","LU1721429402.USD","LU1633808545.USD","LU2092937221.SGD","LU1548497426.USD","ABT","LU2764263039.SGD","BK4568","LU2764263203.CNY","LU2211815571.USD","BK4504","LU1791710400.SGD","LU0234572021.USD","BK4548","IE00B19Z8X17.USD","LU1923621640.USD","IE0009355771.USD","BK4585","LU0640476718.USD","LU1023059063.AUD","LU1169590202.USD","SG9999002232.USD","LU2468319806.SGD","LU0096362180.USD","LU1691799644.USD","SG9999004303.SGD","LU1854103824.USD","LU2125909593.SGD"],"gpt_icon":0},{"id":"2522226555","title":"FDA Issues Complete Response Letter for Etripamil for PSVT","url":"https://stock-news.laohu8.com/highlight/detail?id=2522226555","media":"GlobeNewswire","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2522226555?lang=en_us&edition=fundamental","pubTime":"2025-03-28 19:00","pubTimestamp":1743159600,"startTime":"0","endTime":"0","summary":"CRL focused on CMC; no clinical issues relating to etripamil raised. $69.7M in cash, cash equivalents and short-term investments as of December 31, 2024. MONTREAL and CHARLOTTE, N.C., March 28, 2025  -- Milestone Pharmaceuticals Inc. today announced the U.S. Food and Drug Administration  issued a Complete Response Letter  regarding its New Drug Application  for CARDAMYST  nasal spray, a prescription medication in development for the conversion of acute episodes of PSVT to sinus rhythm in adults.The FDA did not raise any concerns regarding etripamil clinical safety or efficacy data and highlighted two key Chemistry, Manufacturing and Controls  issues to be addressed:. Company to submit additional information on nitrosamine impurities based on new draft guidance issued after the NDA submission; and","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/fda-issues-complete-response-letter-110000561.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LU0149725797.USD","BK4007","BK4006","LU0971096721.USD","CRL","IE00B1BXHZ80.USD","IE00BKVL7J92.USD","MIST","LU0390134368.USD","LU0882574139.USD","IE00BZ1G4Q59.USD","BK4588","BK4121","CMC","LU0170899867.USD","LU1363072403.SGD","IE00BHPRN162.USD","LU0267386448.USD","BK4585","BK4530"],"gpt_icon":0},{"id":"2522564183","title":"Charles River Laboratories International Inc. Stock Underperforms Wednesday When Compared To Competitors","url":"https://stock-news.laohu8.com/highlight/detail?id=2522564183","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2522564183?lang=en_us&edition=fundamental","pubTime":"2025-03-27 05:22","pubTimestamp":1743024120,"startTime":"0","endTime":"0","summary":"This article was automatically generated by MarketWatch using technology from Automated Insights.Shares of Charles River Laboratories International Inc.  slid 1.92% to $158.25 Wednesday, on what proved to be an all-around dismal trading session for the stock market, with the S&P 500 Index  falling 1.12% to 5,712.20 and Dow Jones Industrial Average  falling 0.31% to 42,454.79.This was the stock's third consecutive day of losses.Charles River Laboratories International Inc. closed 42.10% below its 52-week high of $273.32, which the company achieved on April 1st.The stock demonstrated a mixed performance when compared to some of its competitors Wednesday, as Labcorp Holdings Inc.  fell 0.47% to $233.34, Alnylam Pharmaceuticals Inc.  fell 4.18% to $269.21, and Bio-Techne Corp.  fell 1.00% to $59.38.Trading volume  remained 485,624 below its 50-day average volume of 1.3 M.Data source: Dow Jones Market Data, FactSet. Data compiled March 26, 2025.This content was created by MarketWatch, which","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["CRL"],"gpt_icon":0},{"id":"2522664838","title":"Charles River Laboratories International Inc. Stock Sheds 3.4%, Underperforms Competitors","url":"https://stock-news.laohu8.com/highlight/detail?id=2522664838","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2522664838?lang=en_us&edition=fundamental","pubTime":"2025-03-26 04:34","pubTimestamp":1742934840,"startTime":"0","endTime":"0","summary":"This article was automatically generated by Dow Jones using technology from Automated Insights.Shares of Charles River Laboratories International Inc. shed 3.4% to $161.35 on what proved to be an all-around positive trading session for the stock market, with the S&P 500 Index rising 0.2% to 5,776.65 and the Dow Jones Industrial Average rising 0.0% to 42,587.50.This was the stock's second consecutive day of losses.Charles River Laboratories International Inc. closed 41.0% short of its 52-week high of $273.32, which the company achieved on April 1st.The stock underperformed when compared to some of its competitors, as Labcorp Holdings Inc. fell 0.8% to $234.45, Alnylam Pharmaceuticals Inc. fell 3.4% to $280.96, and Bio-Techne Corp. fell 1.78% to $59.98.Trading volume totaled 909,362, compared to the 50-day average of 1.3 million.","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["CRL"],"gpt_icon":0},{"id":"2522184076","title":"Charles River, Valo Health Identify First Lupus Treatment Candidate Using Logica AI Platform","url":"https://stock-news.laohu8.com/highlight/detail?id=2522184076","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2522184076?lang=en_us&edition=fundamental","pubTime":"2025-03-25 20:58","pubTimestamp":1742907527,"startTime":"0","endTime":"0","summary":"Charles River Laboratories International  and Valo Health said Tuesday they identified their first advanceable product candidate for lupus and other autoimmune diseases using Logica.The companies said Logica, an AI-powered drug development program born from their strategic partnership, translates biological insights into optimized preclinical assets.The Logica Advanceable Lead program combines Valo's DNA-encoded libraries and Opal Computational Platform with Charles River's high-throughput screening to produce advanceable leads, they said.CRL shares were 0.8% higher in recent premarket activity.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK7095","BK4588","CRL.AU","BK4585","CRL","LU0390134368.USD","BK4121","BK4530"],"gpt_icon":0},{"id":"2522224000","title":"Charles River and Valo Health Identify Potential Therapeutic for Lupus Using Logica","url":"https://stock-news.laohu8.com/highlight/detail?id=2522224000","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2522224000?lang=en_us&edition=fundamental","pubTime":"2025-03-25 20:04","pubTimestamp":1742904263,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250325:nFWN3Q71RU:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["LU0390134368.USD","BK4588","CRL","BK4121","BK4530","BK4585"],"gpt_icon":0},{"id":"2522040077","title":"Charles River and Valo Health Identify a Potential Therapeutic for Lupus Using Logica®, an AI-Powered Drug Discovery Platform","url":"https://stock-news.laohu8.com/highlight/detail?id=2522040077","media":"Business Wire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2522040077?lang=en_us&edition=fundamental","pubTime":"2025-03-25 20:00","pubTimestamp":1742904000,"startTime":"0","endTime":"0","summary":"First Logica-identified candidate marks a progression-based milestone in ongoing partnership with Pioneering Medicines, Flagship Pioneering’s in-house drug development unit. \"Identification of this first lead candidate provides proof-of-concept for Logica as an engine to expedite and enhance drug discovery in a critical therapeutic area,\" said Professor Julie Frearson, PhD, Senior Vice President and Chief Scientific Officer, Charles River. \"Together with our partners at Valo Health and through our ongoing collaboration with Flagship’s Pioneering Medicines, we look forward to further leveraging the power of Logica to advance this program into lead optimization.\". Logica, the result of a strategic partnership between Charles River and Valo Health, is the industry’s first computation-powered, unified target-to-candidate offering. Logica leverages the integration of Valo Health’s AI-powered Opal Computational Platform and Charles River’s leading expertise in drug discovery and preclinical ","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/charles-river-valo-health-identify-120000756.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4548","BK4588","BK4532","BK4533","FHTX","LU0390134368.USD","BK4551","BK4568","BK4121","CRL","SANA","BK4501","BK4139","BK4534","MRNA","BK4585","BK4530"],"gpt_icon":0},{"id":"2522706599","title":"ABEO: Countdown to PDUFA Date of April 29, 2025…","url":"https://stock-news.laohu8.com/highlight/detail?id=2522706599","media":"Zacks Small Cap Research","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2522706599?lang=en_us&edition=fundamental","pubTime":"2025-03-24 22:04","pubTimestamp":1742825040,"startTime":"0","endTime":"0","summary":"Abeona Therapeutics, Inc.  is continuing preparations for the potential commercial launch of prademagene zamikeracel , which has a PDUFA target action date of April 29, 2025. The company resubmitted the Biologics License Application  following receipt of a Complete Response Letter  in 2024 in which the FDA identified the need for additional Chemistry, Manufacturing and Controls  data pertaining to the validation of certain manufacturing and release testing methods. Abeona aligned with the FDA on the content necessary for resubmission of the BLA and is confident that it met all of the agency’s requests. In the CRL, the FDA did not identify any deficiencies related to the clinical efficacy or clinical safety data, there were no requests for additional clinical data or any new clinical trials, and the FDA does not plan on conducting an Advisory Committee meeting regarding the 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