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Aprea Therapeutics, Inc.

0.6830

-0.0170-2.43%

Post-market: 0.6350-0.0480-7.03%19:54 EDT

Volume:77.92K

Turnover:55.15K

Market Cap:7.82M

PE:-0.35

High:0.7280

Open:0.7280

Low:0.6830

Close:0.7000

52wk High:2.30

52wk Low:0.5480

Shares:11.45M

Float Shares:9.68M

Volume Ratio:1.26

T/O Rate:0.80%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-1.9300

EPS(LYR):-1.9269

ROE:-74.58%

ROA:-41.45%

PB:0.63

PE(LYR):-0.35

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Overview Company News Filings

Aprea Therapeutics announces early PoC data in ACESOT-1051 trial

Aprea Therapeutics Reports Early Proof-of-Concept for WEE1 Inhibitor APR-1051 in Solid Tumors

Aprea Therapeutics Inc - 50% Reduction in Lesion, 90% Decrease in CA-125 in Patient

THOMSON REUTERS

Aprea Therapeutics Announces Early Clinical Proof-of-Concept in the Ongoing Acesot-1051 Dose-Escalation Trial Evaluating Wee1 Inhibitor Apr-1051, Including Partial Response Observed on First Scan

THOMSON REUTERS

Aprea Therapeutics Inc - Unconfirmed Partial Response at 150 Mg Dose

THOMSON REUTERS

Aprea Therapeutics Inc: Additional Updates in First Half of 2026 and Completing Dose Escalation Later in Year

THOMSON REUTERS

Aprea Therapeutics Announces $5.6 Million Private Placement Priced at-the-Market Under Nasdaq Rules

THOMSON REUTERS

Aprea Therapeutics Faces Nasdaq Delisting Risk Over Minimum Bid Price

U.S. RESEARCH ROUNDUP-Comerica, Heico, Walmart

Aprea Therapeutics Inc - Files Prospectus for Resale of 5.5 Mln Shares by the Selling Stockholders - SEC Filing

THOMSON REUTERS

Aprea Therapeutics, Inc. : H.c. Wainwright Cuts Target Price to $5 From $20

THOMSON REUTERS

BRIEF-Aprea Therapeutics CEO Issues Letter To Shareholders Highlighting Outlook For 2026

Aprea Therapeutics Inc - Pauses Enrollment in Aboya-119 Study Monotherapy Arms

THOMSON REUTERS

Director Marc Duey Reports Acquisition of Common Shares in Aprea Therapeutics Inc

Aprea Therapeutics CFO John P. Hamill Reports Acquisition of Common Shares

Aprea Therapeutics Inc - Net Proceeds Expected to Fund Aprea Into 2027

THOMSON REUTERS

Press Release: Aprea Therapeutics Announces $3.1 Million Private Placement Priced At-The-Market Under Nasdaq Rules

Aprea Therapeutics Reports Continued Clinical Progress and Extends Cash Runway Into Q4 2026

Aprea Therapeutics Advances WEE1 Inhibitor APR-1051 in Phase 1 Trial for Hard-to-Treat Cancers

Aprea Therapeutics Inc - Has Cash Runway Into Q4 2026

THOMSON REUTERS

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Therapeutics announces early PoC data in ACESOT-1051 trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2607038800","media":"TIPRANKS","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2607038800?lang=en_us&edition=fundamental","pubTime":"2026-01-29 21:36","pubTimestamp":1769693807,"startTime":"0","endTime":"0","summary":"Aprea Therapeutics (APRE) announced the first unconfirmed partial response observed in a patient enrolled in its ongoing Phase 1 ACESOT-1051 dose-e...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/aprea-therapeutics-announces-early-poc-data-in-acesot-1051-trial-thefly?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/aprea-therapeutics-announces-early-poc-data-in-acesot-1051-trial-thefly?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["APRE","BK4539","LENZ","BK4007","BK4139"],"gpt_icon":0},{"id":"2607908094","title":"Aprea Therapeutics Reports Early Proof-of-Concept for WEE1 Inhibitor APR-1051 in Solid Tumors","url":"https://stock-news.laohu8.com/highlight/detail?id=2607908094","media":"Reuters","labels":["express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2607908094?lang=en_us&edition=fundamental","pubTime":"2026-01-29 21:27","pubTimestamp":1769693229,"startTime":"0","endTime":"0","summary":"Aprea Therapeutics Inc. announced early clinical proof-of-concept results from its ongoing Phase 1 ACESOT-1051 dose-escalation trial evaluating the WEE1 inhibitor APR-1051 in patients with advanced solid tumors. Preliminary data include the observation of an unconfirmed partial response in a patient with endometrial cancer at the 150 mg dose, with approximately 50% reduction in target lesion size and greater than 90% decrease in CA-125 levels. The study is currently enrolling patients in the 220 mg cohort, with a potential dose-response trend observed across the 70 mg, 100 mg, and 150 mg groups. Additional study updates are expected in the first half of 2026, and dose escalation is anticipated to be completed later in the year.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260129:nNDL3LQq0M:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4585","IE00BGHQF748.EUR","IE00BKPKM429.USD","LU2210149790.SGD","SG9999014021.USD","BK4112","SG9999014005.SGD","IE00B64PRP62.GBP","LU2095319765.USD","SG9999014013.SGD","LU2210150020.SGD","BK4139","APRE","BK4588","NDAQ","LU0314104364.USD","SG9999014039.USD","IE00B3QW5Z07.USD"],"gpt_icon":0},{"id":"2607919080","title":"Aprea Therapeutics Inc - 50% Reduction in Lesion, 90% Decrease in CA-125 in Patient","url":"https://stock-news.laohu8.com/highlight/detail?id=2607919080","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2607919080?lang=en_us&edition=fundamental","pubTime":"2026-01-29 21:27","pubTimestamp":1769693220,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260129:nTUA8ZZFZZ:3","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["APRE","BK4139"],"gpt_icon":0},{"id":"2607080997","title":"Aprea Therapeutics Announces Early Clinical Proof-of-Concept in the Ongoing Acesot-1051 Dose-Escalation Trial Evaluating Wee1 Inhibitor Apr-1051, Including Partial Response Observed on First Scan","url":"https://stock-news.laohu8.com/highlight/detail?id=2607080997","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2607080997?lang=en_us&edition=fundamental","pubTime":"2026-01-29 21:27","pubTimestamp":1769693220,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260129:nTUA8ZZFZZ:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","APRE"],"gpt_icon":0},{"id":"2607080913","title":"Aprea Therapeutics Inc - Unconfirmed Partial Response at 150 Mg Dose","url":"https://stock-news.laohu8.com/highlight/detail?id=2607080913","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2607080913?lang=en_us&edition=fundamental","pubTime":"2026-01-29 21:27","pubTimestamp":1769693220,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260129:nTUA8ZZFZZ:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","APRE"],"gpt_icon":0},{"id":"2607080910","title":"Aprea Therapeutics Inc: Additional Updates in First Half of 2026 and Completing Dose Escalation Later in Year","url":"https://stock-news.laohu8.com/highlight/detail?id=2607080910","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2607080910?lang=en_us&edition=fundamental","pubTime":"2026-01-29 21:27","pubTimestamp":1769693220,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260129:nTUA8ZZFZZ:4","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["APRE","BK4139"],"gpt_icon":0},{"id":"2607080958","title":"Aprea Therapeutics Announces $5.6 Million Private Placement Priced at-the-Market Under Nasdaq Rules","url":"https://stock-news.laohu8.com/highlight/detail?id=2607080958","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2607080958?lang=en_us&edition=fundamental","pubTime":"2026-01-29 21:25","pubTimestamp":1769693100,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260129:nTUA4CTXPG:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","APRE"],"gpt_icon":0},{"id":"2606029763","title":"Aprea Therapeutics Faces Nasdaq Delisting Risk Over Minimum Bid Price","url":"https://stock-news.laohu8.com/highlight/detail?id=2606029763","media":"Reuters","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2606029763?lang=en_us&edition=fundamental","pubTime":"2026-01-26 15:49","pubTimestamp":1769413786,"startTime":"0","endTime":"0","summary":"Aprea Therapeutics Inc. has received a deficiency letter from the Nasdaq Listing Qualifications Department, notifying the company that its common stock has traded below the minimum required bid price of $1.00 per share for 30 consecutive business days. This puts Aprea at risk of being delisted from the Nasdaq Capital Market if it does not regain compliance within a 180-day period ending July 22, 2026. The company may seek a second compliance period or appeal a delisting determination if necessary. Aprea Therapeutics is considering actions such as a reverse stock split to address the issue, but there is no assurance it will regain compliance.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Aprea Therapeutics Inc. published the original c","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260126:nNDL2WWzC2:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["APRE","BK4139"],"gpt_icon":0},{"id":"2593510240","title":"U.S. RESEARCH ROUNDUP-Comerica, Heico, Walmart","url":"https://stock-news.laohu8.com/highlight/detail?id=2593510240","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2593510240?lang=en_us&edition=fundamental","pubTime":"2025-12-22 15:49","pubTimestamp":1766389793,"startTime":"0","endTime":"0","summary":"U.S. RESEARCH ROUNDUP-Comerica, Heico, WalmartDec 22 (Reuters) - Wall Street securities analysts revised their ratings and price targets on several U.S.-listed companies, including Comerica, Heico and","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251222:nL4N3XS0F2:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4516","COF","HEI","DKNG","LEU","FOLD","BKSY","ASB","DRI","LU0052756011.USD","CAG","ELF","ALZN","CUBE","BOW","LU0187121727.USD","AZZ","CRSR","GAP","FBLG","CNTX","FITB","LU2242649171.HKD","CCL","CYTK","ALLY","AXP","LU1951200564.SGD","T","FRT","CMA","ANF","LU0689472784.USD","BMRN","FISV","AKTX","AFL","CWAN","EOSE","CINF","GOOGL","CFG","LU0323591593.USD","APRE","LU2275660780.HKD","LU1116320737.USD","BMBL","IE00B19Z8X17.USD","FLUT","AIG"],"gpt_icon":1},{"id":"2592197272","title":"Aprea Therapeutics Inc - Files Prospectus for Resale of 5.5 Mln Shares by the Selling Stockholders - SEC Filing","url":"https://stock-news.laohu8.com/highlight/detail?id=2592197272","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2592197272?lang=en_us&edition=fundamental","pubTime":"2025-12-20 05:13","pubTimestamp":1766178838,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251219:nFWN3XP0GA:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["APRE","BK4139"],"gpt_icon":0},{"id":"2592918892","title":"Aprea Therapeutics, Inc. : H.c. Wainwright Cuts Target Price to $5 From $20","url":"https://stock-news.laohu8.com/highlight/detail?id=2592918892","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2592918892?lang=en_us&edition=fundamental","pubTime":"2025-12-19 00:29","pubTimestamp":1766075380,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251218:nAZN4RGRLS:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["APRE","BK4139"],"gpt_icon":0},{"id":"2592690723","title":"BRIEF-Aprea Therapeutics CEO Issues Letter To Shareholders Highlighting Outlook For 2026","url":"https://stock-news.laohu8.com/highlight/detail?id=2592690723","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2592690723?lang=en_us&edition=fundamental","pubTime":"2025-12-18 23:17","pubTimestamp":1766071065,"startTime":"0","endTime":"0","summary":"BRIEF-Aprea Therapeutics CEO Issues Letter To Shareholders Highlighting Outlook For 2026Dec 18 (Reuters) - Aprea Therapeutics Inc APRE.O:APREA THERAPEUTICS CEO ISSUES LETTER TO SHAREHOLDERS HIGHLIGHTI","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251218:nTUA65LQYL:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["APRE","BK4139"],"gpt_icon":0},{"id":"2592909964","title":"Aprea Therapeutics Inc - Pauses Enrollment in Aboya-119 Study Monotherapy Arms","url":"https://stock-news.laohu8.com/highlight/detail?id=2592909964","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2592909964?lang=en_us&edition=fundamental","pubTime":"2025-12-18 21:30","pubTimestamp":1766064601,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251218:nTUA65LQYL:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","APRE"],"gpt_icon":0},{"id":"2590551934","title":"Director Marc Duey Reports Acquisition of Common Shares in Aprea Therapeutics Inc","url":"https://stock-news.laohu8.com/highlight/detail?id=2590551934","media":"Reuters","labels":["shareholding","insiderTrades","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2590551934?lang=en_us&edition=fundamental","pubTime":"2025-12-11 21:32","pubTimestamp":1765459954,"startTime":"0","endTime":"0","summary":"Marc Duey, Director of Aprea Therapeutics Inc., reported the acquisition of common shares of the company. The full filing can be accessed through the link below.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Aprea Therapeutics Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on December 11, 2025, and is solely responsible for the information contained therein.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251211:nNDL8XDqRx:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":"Director Marc Duey Reports Acquisition of Common Shares in Aprea Therapeutics Inc","news_tag":"shareholding,insiderTrades,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","APRE"],"gpt_icon":0},{"id":"2590519366","title":"Aprea Therapeutics CFO John P. Hamill Reports Acquisition of Common Shares","url":"https://stock-news.laohu8.com/highlight/detail?id=2590519366","media":"Reuters","labels":["shareholding","insiderTrades","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2590519366?lang=en_us&edition=fundamental","pubTime":"2025-12-11 21:31","pubTimestamp":1765459897,"startTime":"0","endTime":"0","summary":"John P. Hamill, Senior Vice President, Chief Financial Officer, and Principal Financial & Accounting Officer of Aprea Therapeutics Inc., has reported the acquisition of common shares of the company. The full filing can be accessed through the link below.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Aprea Therapeutics Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on December 11, 2025, and is solely responsible for the information contained therein.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251211:nNDLtkc4G:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"shareholding,insiderTrades,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4588","BK4534","PFG","BK4566","BK4162","BK4585","LU1989772923.USD","BK4139","LU1989772840.SGD","APRE"],"gpt_icon":0},{"id":"2590341562","title":"Aprea Therapeutics Inc - Net Proceeds Expected to Fund Aprea Into 2027","url":"https://stock-news.laohu8.com/highlight/detail?id=2590341562","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2590341562?lang=en_us&edition=fundamental","pubTime":"2025-12-09 21:30","pubTimestamp":1765287002,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251209:nTUA91RFGD:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","APRE"],"gpt_icon":0},{"id":"2590341337","title":"Press Release: Aprea Therapeutics Announces $3.1 Million Private Placement Priced At-The-Market Under Nasdaq Rules","url":"https://stock-news.laohu8.com/highlight/detail?id=2590341337","media":"Dow Jones","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2590341337?lang=en_us&edition=fundamental","pubTime":"2025-12-09 21:30","pubTimestamp":1765287000,"startTime":"0","endTime":"0","summary":"Financing from new and existing healthcare focused investors. The proceeds are expected to extend the Company's cash runway into Q1 2027, with potential inflection points anticipated in its clinical programs during that period. The offer and sale of the foregoing securities are being made in a private placement under Section 4 of the Securities Act of 1933, as amended , and/or Regulation D promulgated thereunder, and the securities have not been registered under the Securities Act or applicable state securities laws. Accordingly, the securities may not be reoffered or resold in the United States except pursuant to an effective registration statement or an applicable exemption from the registration requirements of the Securities Act and such applicable state securities laws. The Company has agreed to file a registration statement with the Securities and Exchange Commission registering the resale of the securities purchased in the private placement.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","NQmain","BK4007","APRE","BK4539","LENZ"],"gpt_icon":0},{"id":"2582745603","title":"Aprea Therapeutics Reports Continued Clinical Progress and Extends Cash Runway Into Q4 2026","url":"https://stock-news.laohu8.com/highlight/detail?id=2582745603","media":"Reuters","labels":["dataReport","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2582745603?lang=en_us&edition=fundamental","pubTime":"2025-11-12 21:36","pubTimestamp":1762954568,"startTime":"0","endTime":"0","summary":"Aprea Therapeutics Inc. announced its financial results for the third quarter ended September 30, 2025, and provided a business update. The company reported continued progress in its WEE1 and ATR inhibitor programs and stated it has a cash runway into the fourth quarter of 2026. In the ongoing Phase 1 ACESOT-1051 dose-escalation trial for APR-1051, a WEE1 kinase inhibitor, 3 out of 4 patients at Dose Level 6  achieved stable disease, according to RECIST v1.1, among heavily pretreated patients with gastrointestinal and gynecologic malignancies. The company has recently advanced to the 150 mg once daily cohort as dose escalation continues. For ATRN-119, an ATR kinase inhibitor, the recommended Phase 2 dose  of 1,100 mg once daily was identified in the ABOYA-119 dose-escalation study. Aprea is considering potential combination strategies for ATRN-119, including with radiation or checkpoint inhibitors. Posters with updated data for both APR-1051 and ATRN-119 were presented at the AACR-NCI-","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251112:nNDL9GbWgf:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["APRE","BK4139"],"gpt_icon":0},{"id":"2582537453","title":"Aprea Therapeutics Advances WEE1 Inhibitor APR-1051 in Phase 1 Trial for Hard-to-Treat Cancers","url":"https://stock-news.laohu8.com/highlight/detail?id=2582537453","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2582537453?lang=en_us&edition=fundamental","pubTime":"2025-11-12 21:30","pubTimestamp":1762954230,"startTime":"0","endTime":"0","summary":"Aprea Therapeutics Inc. has announced updates on its ongoing clinical trials for two investigational cancer therapies, APR-1051 and ATRN-119. In the Phase 1 ACESOT-1051 dose-escalation trial of APR-1051, a WEE1 kinase inhibitor, 3 out of 4 patients at the 100 mg once daily dose level achieved stable disease in heavily pretreated gastrointestinal and gynecologic malignancies. Dose escalation has continued to the 150 mg once daily cohort. For ATRN-119, an ATR kinase inhibitor, the recommended Phase 2 dose  has been identified as 1,100 mg once daily in the ABOYA-119 dose-escalation study. Results from these studies were presented in posters at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics on October 24, 2025. Future studies may evaluate APR-1051 in combination with checkpoint inhibitors.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. 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