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Denali Therapeutics Inc.

20.57

0.0000

盤後：20.570.00000.00%19:59 EDT

成交量：145.47萬

成交額：3,018.41萬

市值：32.62億

市盈率：-6.93

高：21.16

開：20.54

低：20.31

收：20.57

52周最高：23.77

52周最低：10.57

股本：1.59億

流通股本：1.44億

量比：0.87

換手率：1.01%

股息：- -

股息率：- -

每股收益(TTM):-2.9700

每股收益(LYR):-2.9700

淨資產收益率：-45.69%

總資產收益率：-27.56%

市淨率：3.22

市盈率(LYR):-6.93

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淡馬錫持倉+1.43%

巴美列捷福持倉+1.32%

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新聞資訊

Denali Therapeutics公布2025年第四季度及全年財務業績與業務亮點

Denali Therapeutics：FDA「黑天鵝」驚雷後，TV平台如何攻克血腦屏障，引領CNS罕見病新紀元？

医道社创新药新...

Denali Therapeutics將公布酶轉運載體項目數據，聚焦亨特綜合徵、A型桑菲利波綜合徵及龐貝病治療進展

Denali Therapeutics公布2026年關鍵預期里程碑與優先事項含Hunter綜合徵療法Tividenofusp Alfa的商業化上市

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(DNLI) 近日披露了其2025年第四季度及全年的财务报告，并同步分享了公司在此期间取得的重要业务进展。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4548","BK4535","BK4139","DNLI"],"gpt_icon":0},{"id":"2608002929","title":"Denali Therapeutics：FDA「黑天鵝」驚雷後，TV平台如何攻克血腦屏障，引領CNS罕見病新紀元？","url":"https://stock-news.laohu8.com/highlight/detail?id=2608002929","media":"医道社创新药新...","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2608002929?lang=zh_tw&edition=fundamental","pubTime":"2026-02-01 11:45","pubTimestamp":1769917538,"startTime":"0","endTime":"0","summary":"今天，我想和各位临床医生、药品研发同行们聊聊Denali Therapeutics。这家公司最近因为竞争对手Regenxbio的基因疗法试验被FDA冻结，股价暴涨3.7%，市值冲上33.7亿美元。基因分析显示，AAV病毒载体整合入肿瘤基因组，引发致癌基因突变。RGX-121的PDUFA原定2月8日，现在大概率推迟或重审。Fierce Biotech 2025年报道直言，AAV的“一次性高风险”在CNS领域越来越难站稳脚跟。Fierce Biotech 2025称TV是“BBB突破的游戏改变者”，模块化设计让Denali从罕见病跃升主流神经领域。","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tencent","url":"http://gu.qq.com/resources/shy/news/detail-v2/index.html#/?id=nesSN2026020113053597a45036&s=b","rn_cache_url":null,"customStyle":"body{padding-top:10px;}#news_title{font-weight:bold;#titleStyle#;}#news_description span{font-size:12px;#descriptionStyle#;}.footer-note{#statement#}","selectors":".mod-LoadTzbdNews, body","filters":".relate-stock, .hot-list, .recom-box, .wx-sou","directOrigin":true},"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"http://gu.qq.com/resources/shy/news/detail-v2/index.html#/?id=nesSN2026020113053597a45036&s=b","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tencent","symbols":["BK4135","DNLI","BK4539","CNS","BK4100","BK4535","LENZ","TV","BK4139","BK4548","BK4007"],"gpt_icon":0},{"id":"1130865050","title":"Denali Therapeutics將公布酶轉運載體項目數據，聚焦亨特綜合徵、A型桑菲利波綜合徵及龐貝病治療進展","url":"https://stock-news.laohu8.com/highlight/detail?id=1130865050","media":"美股速递","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1130865050?lang=zh_tw&edition=fundamental","pubTime":"2026-01-30 05:00","pubTimestamp":1769720422,"startTime":"0","endTime":"0","summary":"Denali Therapeutics Inc.近日宣布，将在2026年世界研讨会上展示其酶转运载体技术平台在亨特综合征、A型桑菲利波综合征以及庞贝病治疗领域的多项研究数据。此次公布的数据将涵盖临床前及早期临床研究结果，重点展示酶转运载体技术在突破血脑屏障、提升治疗效率方面的潜力。公司表示，这些数据的发布将为进一步推进罕见病治疗方案的临床开发提供重要科学依据。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4548","DNLI","BK4535","BK4139"],"gpt_icon":0},{"id":"1153996693","title":"Denali Therapeutics公布2026年關鍵預期里程碑與優先事項 含Hunter綜合徵療法Tividenofusp Alfa的商業化上市","url":"https://stock-news.laohu8.com/highlight/detail?id=1153996693","media":"美股速递","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1153996693?lang=zh_tw&edition=fundamental","pubTime":"2026-01-06 21:12","pubTimestamp":1767705146,"startTime":"0","endTime":"0","summary":"Denali Therapeutics Inc. (DNLI) 近日披露了公司2026年的战略路线图，其中最具里程碑意义的规划涉及治疗亨特综合征（Hunter Syndrome）的创新疗法Tividenofusp Alfa的正式商业化推进。该生物制药企业明确将此项产品的市场投放列为明年核心优先任务之一，标志着其在罕见病治疗领域的重要布局即将进入收获阶段。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4548","BK4535","BK4139","DNLI"],"gpt_icon":0}],"pageSize":4,"totalPage":4,"pageCount":1,"totalSize":13,"code":"91000000","status":"200"}],"@#url:\"https://hq.skytigris.cn/market/plate/belongs/DNLI\",params:#limit:6,delay:false,,,undefined,":[{"market":"US","name":"淡馬錫持倉","bkCode":"BK4535","id":"package_us_concept_dmxcc","changeRate":0.01428},{"market":"US","name":"巴美列捷福持倉","bkCode":"BK4548","id":"package_us_concept_bmljfcc","changeRate":0.013158}]}}