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Ionis Pharmaceuticals

41.76

-0.4100-0.97%

Post-market: 41.760.00000.00%16:10 EDT

Volume:1.27M

Turnover:52.83M

Market Cap:6.65B

PE:-13.93

High:42.57

Open:42.15

Low:41.25

Close:42.17

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Overview Company News Filings

U.S. RESEARCH ROUNDUP-Alnylam Pharmaceuticals, Beacon Roofing, Liberty Energy

Ionis Pharmaceuticals: Strategic Partnerships and Financial Flexibility Drive Buy Rating

Ionis Pharmaceuticals Inc : Leerink Partners Raises Target Price to $55 From $52

THOMSON REUTERS

BRIEF-Ionis And Ono Announce Global License Agreement For Sapablursen In Polycythemia Vera

Ionis and Ono announce global license agreement for sapablursen in polycythemia vera

Ionis Pharmaceuticals Is Maintained at Neutral by JP Morgan

IONS/AZN Get FDA Nod for Amyloidosis Drug, Wainzua in Europe

Ionis Pharmaceuticals Says Transthyretin-Mediated Amyloidosis Treatment Gets Approval in Europe

MT Newswires Live

BRIEF-WAINZUA (Eplontersen) Approved In The EU For The Treatment Of Hereditary Transthyretin-Mediated Amyloidosis In Adults With Stage 1 Or Stage 2 Polyneuropathy

Wainzua (Eplontersen) Approved in the EU for the Treatment of Hereditary Transthyretin-Mediated Amyloidosis in Adults With Stage 1 or Stage 2 Polyneuropathy

THOMSON REUTERS

WAINZUA (eplontersen) approved in the EU for the treatment of hereditary transthyretin-mediated amyloidosis in adults with stage 1 or stage 2 polyneuropathy

Theratechnologies Inc (THTX) Q4 2024 Earnings Call Highlights: Strong EBITDA Turnaround and ...

Ionis to present at upcoming investor conferences

The Zacks Analyst Blog Highlights Merck, Sanofi, Regeneron and Ionis

Optimistic Future Outlook for Ionis Pharmaceuticals Driven by Robust Growth and Strategic Initiatives

Ionis Pharmaceuticals price target lowered to $60 from $61 at Raymond James

Pharma Stock Roundup: EU Nod to MRK's Welireg, IONS' Q4 Results & More

Ionis Pharmaceuticals Inc : Bernstein Cuts Target Price to $43 From $51

THOMSON REUTERS

BRIEF-New Positive Donidalorsen Data To Be Presented At Aaaai/Wao Joint Congress

New Positive Donidalorsen Data to Be Presented at Aaaai/Wao Joint Congress Highlight Sustained Hae Attack Rate Reduction and Disease Control

THOMSON REUTERS

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Ionis Pharmaceuticals Inc IONS.O:IONIS AND ONO ANNOUNCE GLOBAL LICENSE AGREEMENT FOR SAPABLURSEN IN POLYCYTHEMIA VERASource text: ID:nBwnhhkpaFurther company coverage: IONS.O","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250311:nFWN3PU17M:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS","BK4139"],"gpt_icon":0},{"id":"2518705907","title":"Ionis and Ono announce global license agreement for sapablursen in polycythemia vera","url":"https://stock-news.laohu8.com/highlight/detail?id=2518705907","media":"Business Wire","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2518705907?lang=en_us&edition=fundamental","pubTime":"2025-03-12 06:00","pubTimestamp":1741730400,"startTime":"0","endTime":"0","summary":"CARLSBAD, Calif. & OSAKA, Japan, March 11, 2025----Ionis Pharmaceuticals, Inc.  and Ono Pharmaceutical Co., Ltd , today announced that the two companies have entered into a license agreement in which Ono obtains exclusive global rights for the development and commercialization of sapablursen, an investigational RNA-targeted medicine for polycythemia vera , a rare and potentially life-threatening hematologic disease. Sapablursen is currently being evaluated in adults living with PV in the fully enrolled Phase 2 IMPRSSION study. Sapablursen was granted Fast Track designation and orphan drug designation in 2024 by the U.S. Food and Drug Administration .Under the terms of the agreement, Ionis will receive a $280 million upfront payment, with the potential to earn up to $660 million in additional payments based on the achievement of development, regulatory and sales milestones. Ionis is also eligible to earn royalties in the mid-teen percentage range on annual net sales of sapablursen. Ioni","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/ionis-ono-announce-global-license-220000549.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"corporation","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4139","IONS"],"gpt_icon":0},{"id":"2518237937","title":"Ionis Pharmaceuticals Is Maintained at Neutral by JP Morgan","url":"https://stock-news.laohu8.com/highlight/detail?id=2518237937","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2518237937?lang=en_us&edition=fundamental","pubTime":"2025-03-11 23:05","pubTimestamp":1741705500,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/IONS/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  March 11, 2025 11:05 ET (15:05 GMT)","market":"other","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"gpt_icon":0},{"id":"2518723100","title":"IONS/AZN Get FDA Nod for Amyloidosis Drug, Wainzua in Europe","url":"https://stock-news.laohu8.com/highlight/detail?id=2518723100","media":"Zacks","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2518723100?lang=en_us&edition=fundamental","pubTime":"2025-03-11 20:43","pubTimestamp":1741696980,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals IONS announced that the European Commission  has approved Wainzua  for treating adult patients with hereditary transthyretin-mediated amyloidosis with stage 1 or stage 2 polyneuropathy . The drug has been developed in partnership with AstraZeneca AZN.This approval was expected as the EMA’s Committee for Medicinal Products for Human Use  issued a positive opinion recommending the approval of Wainzua in the above indication in October.The EC and CHMP decisions are based on positive data from the phase III NEURO-TTRansform study, which evaluated the safety and efficacy of Wainzua in patients with ATTRv-PN. Data from this study showed that treatment with the drug led to consistent and sustained benefit in the co-primary endpoints of serum transthyretin  concentration and neuropathy impairment. Treatment with Wainzua also improved quality of life versus placebo, a key secondary endpoint of the NEURO-TTRansform study.ATTRv-PN is a debilitating disease,which leads to per","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/ions-azn-fda-nod-amyloidosis-124300822.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LU2417539215.USD","GSK","LU1169589451.USD","LU2236285917.USD","BK4139","BIIB","BK4007","LU0889565916.HKD","LU1169590202.USD","BK4532","LU1829250122.USD","IE00B894F039.SGD","GSK.UK","LU0205194284.USD","BK4588","AZN","IONS","LU2462157665.USD","BK4533","LU2456880835.USD","BK4568","LU0205193047.USD","LU0320765992.SGD","HAE","LU0234570918.USD","LU0012050646.USD","BK4585","LU0106261612.USD","BK4198","LU0109394709.USD","IE00B64QTZ34.USD","CHB","IE00B19Z9Z06.USD","IE00BLDYK493.USD","IE00B19Z9P08.USD"],"gpt_icon":0},{"id":"2518228454","title":"Ionis Pharmaceuticals Says Transthyretin-Mediated Amyloidosis Treatment Gets Approval in Europe","url":"https://stock-news.laohu8.com/highlight/detail?id=2518228454","media":"MT Newswires Live","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2518228454?lang=en_us&edition=fundamental","pubTime":"2025-03-10 19:58","pubTimestamp":1741607927,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals  said Monday that the company and partner AstraZeneca's  Wainzua received approval in the European Union to treat hereditary transthyretin-mediated amyloidosis in adult patients with stage 1 or stage 2 polyneuropathy, or ATTRv-PN.Wainzua was approved for ATTRv-PN treatment in the US in December 2023 and has received approvals in other countries, including the UK and Canada, the company said.ATTRv-PN results in peripheral nerve damage with motor disability within five years of diagnosis. Without treatment, the disease is \"generally fatal\" within 10 years, Ionis said.Shares of Ionis rose 1.4% in recent premarket activity, while AstraZeneca fell 1.7%.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["AZN","LU0889565916.HKD","LU2417539215.USD","LU1829250122.USD","LU0109394709.USD","BK4588","LU2462157665.USD","BK4007","LU2236285917.USD","BK4585","BK4568","LU2456880835.USD","BK4139","LU0320765992.SGD","IONS"],"gpt_icon":0},{"id":"2518244994","title":"BRIEF-WAINZUA (Eplontersen) Approved In The EU For The Treatment Of Hereditary Transthyretin-Mediated Amyloidosis In Adults With Stage 1 Or Stage 2 Polyneuropathy","url":"https://stock-news.laohu8.com/highlight/detail?id=2518244994","media":"Reuters","labels":["productRelease","event"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2518244994?lang=en_us&edition=fundamental","pubTime":"2025-03-10 19:06","pubTimestamp":1741604770,"startTime":"0","endTime":"0","summary":"BRIEF-WAINZUA (Eplontersen) Approved In The EU For The Treatment Of Hereditary Transthyretin-Mediated Amyloidosis In Adults With Stage 1 Or Stage 2 PolyneuropathyMarch 10 (Reuters) - Ionis Pharmaceuti","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250310:nTUA9HFMMC:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease,event","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS","BK4139"],"gpt_icon":0},{"id":"2518244311","title":"Wainzua (Eplontersen) Approved in the EU for the Treatment of Hereditary Transthyretin-Mediated Amyloidosis in Adults With Stage 1 or Stage 2 Polyneuropathy","url":"https://stock-news.laohu8.com/highlight/detail?id=2518244311","media":"THOMSON REUTERS","labels":["event"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2518244311?lang=en_us&edition=fundamental","pubTime":"2025-03-10 19:00","pubTimestamp":1741604401,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250310:nTUA9HFMMC:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"event","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","IONS"],"gpt_icon":0},{"id":"2518240670","title":"WAINZUA (eplontersen) approved in the EU for the treatment of hereditary transthyretin-mediated amyloidosis in adults with stage 1 or stage 2 polyneuropathy","url":"https://stock-news.laohu8.com/highlight/detail?id=2518240670","media":"Business Wire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2518240670?lang=en_us&edition=fundamental","pubTime":"2025-03-10 19:00","pubTimestamp":1741604400,"startTime":"0","endTime":"0","summary":"– Second major approval for WAINZUA, which is marketed in the U.S. as WAINUA –。– EU approval based on NEURO-TTRansform Phase 3 results showing WAINZUA demonstrated consistent and sustained benefit improving neuropathy impairment and quality of life versus placebo –。CARLSBAD, Calif., March 10, 2025----Ionis Pharmaceuticals, Inc.  announced today that Ionis and AstraZeneca’s WAINZUA  has been approved in the European Union  for the treatment of hereditary transthyretin-mediated amyloidosis in adult patients with stage 1 or stage 2 polyneuropathy, commonly referred to as hATTR-PN or ATTRv-PN. WAINZUA is the only approved medicine in the EU for the treatment of ATTRv-PN that can be self-administered monthly via an auto-injector.ATTR is caused by the accumulation of liver-derived misfolded TTR protein i","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/wainzua-eplontersen-approved-eu-treatment-110000305.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4087","EC","CHMP","IONS","BK4201","PN","BK4156","BK4207","CM","BK4139"],"gpt_icon":0},{"id":"2514823869","title":"Theratechnologies Inc (THTX) Q4 2024 Earnings Call Highlights: Strong EBITDA Turnaround and ...","url":"https://stock-news.laohu8.com/highlight/detail?id=2514823869","media":"GuruFocus.com","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2514823869?lang=en_us&edition=fundamental","pubTime":"2025-02-27 15:09","pubTimestamp":1740640144,"startTime":"0","endTime":"0","summary":"Adjusted EBITDA: $20 million for fiscal year 2024, compared to minus $3 million a year ago.Net Sales: $25 million for Q4 2024, a 6.6% growth versus the same quarter last year.EGRIFTA SV Sales: $17.7 million in Q4 2024, a 4% increase year over year; full year sales were $60 million, representing 12% growth.Trogarzo Sales: $7.3 million in Q4 2024, a 12.8% increase from the same quarter last year; full year sales were $25.7 million, down 8% year over year.Cost of Sales: $6.1 million in Q4 2024, up from $5 million in the same quarter of fiscal 2023.Gross Margin: EGRIFTA SV gross margins at 91% excluding a provision, Trogarzo margins at 48%.R&D Expenses: $2.4 million in Q4 2024, down from $5.2 million last year, excluding impairment loss.Selling Expenses: $7 million in Q4 2024, compared to $6.7 million for the same period last year.G&A Expenses: $5.1 million in Q4 2024, a 38% increase from $3.7 million in Q4 2023.GuruFocus has detected 7 Warning Signs with THTX.Theratechnologies Inc  report","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/theratechnologies-inc-thtx-q4-2024-070904805.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["IONS","THTX"],"gpt_icon":0},{"id":"2514932320","title":"Ionis to present at upcoming investor conferences","url":"https://stock-news.laohu8.com/highlight/detail?id=2514932320","media":"Business Wire","labels":["conferences"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2514932320?lang=en_us&edition=fundamental","pubTime":"2025-02-25 20:05","pubTimestamp":1740485100,"startTime":"0","endTime":"0","summary":"CARLSBAD, Calif., February 25, 2025----Ionis Pharmaceuticals, Inc.  today announced that management will participate in fireside chats at the following investor conferences:. Raymond James 46th Annual Institutional Investors Conference on Tuesday, March 4, 2025. Leerink Partners Global Healthcare Conference 2025 on Tuesday, March 11, 2025. Barclays 27th Annual Global Healthcare Conference on Wednesday, March 12, 2025. UBS Virtual CNS Day 2025 on Monday, March 17, 2025. Stifel 2025 Virtual CNS Forum on Wednesday, March 19, 2025. For three decades, Ionis has invented medicines that bring better futures to people with serious diseases. Ionis currently has six marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient need. As the pioneer in RNA-targeted medicines, Ionis continues to drive innovation in RNA therapies in addition to advancing new approaches in gene editing. A deep understanding of disease biology and industry-leading technology prope","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/ionis-present-upcoming-investor-conferences-120500533.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"conferences","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["IONS","BK4139"],"gpt_icon":0},{"id":"2513744949","title":"The Zacks Analyst Blog Highlights Merck, Sanofi, Regeneron and Ionis","url":"https://stock-news.laohu8.com/highlight/detail?id=2513744949","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2513744949?lang=en_us&edition=fundamental","pubTime":"2025-02-24 17:46","pubTimestamp":1740390360,"startTime":"0","endTime":"0","summary":"Chicago, IL – February 24, 2025 – Zacks.com announces the list of stocks featured in the Analyst Blog. Every day the Zacks Equity Research analysts discuss the latest news and events impacting stocks and the financial markets. Stocks recently featured in the blog include: Merck MRK, Sanofi SNY, Regeneron REGN and Ionis Pharmaceuticals IONS.Pharma Stock Roundup: EU Nod to Key Drug and Q4 Earnings Results. This week, the European Commission granted approval to Merck’s novel HIF-2α inhibitor, Welireg, for two indications. The FDA granted priority review to a supplemental biologics license application  seeking approval of Sanofi and Regeneron’s blockbuster drug, Dupixent, for a new indication, bullous pemphigoid. Ionis Pharmaceuticals announced its fourth-quarter and full-year 2024 results.Here's a recap of the week’s most important stories.EU Approval to Merck’s Welireg for Two Indications. Dupixent is currently approved in several countries, including the United States and EU, for six ty","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/zacks-analyst-blog-highlights-merck-094600312.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LU0265550946.USD","LU0234572021.USD","LU1934455277.USD","SG9999014559.SGD","LU1066051498.USD","LU2112291526.USD","SNY","LU0006306889.USD","LU2237438978.USD","IONS","LU1699723380.USD","LU0320765489.SGD","LU0265550359.USD","LU1989771016.USD","LU2089984988.USD","IE00BBT3K403.USD","LU0106261372.USD","LU0965509010.AUD","LU1929549753.HKD","LU1934455863.HKD","LU1941712264.USD","LU0070302665.USD","LU0058720904.USD","LU1585245621.USD","LU2362541513.USD","SG9999014575.USD","LU1057294990.SGD","LU2361044949.HKD","IE00BFTCPJ56.SGD","LU1066051225.USD","LU1941712348.USD","LU2023250504.SGD","SG9999015358.SGD","LU1989772840.SGD","LU1162221912.USD","MRK","LU0320765646.SGD","LU1093756168.USD","LU0889565916.HKD","LU0985320562.USD","SG9999001440.SGD","LU1989772923.USD","SNYNF","REGN","SGXZ57979304.SGD","LU1116320901.HKD","IE0002141913.USD","LU1430594728.SGD","BK4007","LU2468319806.SGD"],"gpt_icon":0},{"id":"2513628734","title":"Optimistic Future Outlook for Ionis Pharmaceuticals Driven by Robust Growth and Strategic Initiatives","url":"https://stock-news.laohu8.com/highlight/detail?id=2513628734","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2513628734?lang=en_us&edition=fundamental","pubTime":"2025-02-23 19:06","pubTimestamp":1740308802,"startTime":"0","endTime":"0","summary":"Leerink Partners analyst Mani Foroohar has maintained their bullish stance on IONS stock, giving a Buy rating on February 20. Mani Foroohar has giv...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/ratings/optimistic-future-outlook-for-ionis-pharmaceuticals-driven-by-robust-growth-and-strategic-initiatives?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/ratings/optimistic-future-outlook-for-ionis-pharmaceuticals-driven-by-robust-growth-and-strategic-initiatives?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","IONS"],"gpt_icon":0},{"id":"2513941342","title":"Ionis Pharmaceuticals price target lowered to $60 from $61 at Raymond James","url":"https://stock-news.laohu8.com/highlight/detail?id=2513941342","media":"TipRanks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2513941342?lang=en_us&edition=fundamental","pubTime":"2025-02-21 22:35","pubTimestamp":1740148535,"startTime":"0","endTime":"0","summary":"Raymond James lowered the firm’s price target on Ionis Pharmaceuticals  to $60 from $61 and keeps a Strong Buy rating on the shares. Ionis beat nicely in Q4, and the 2025 floor guidance for revenue and operating loss appears reasonable as Ionis transitions to more of a commercial story, the analyst tells investors in a research note.Discover the Best Stocks and Maximize Your Portfolio:. See what stocks are receiving strong buy ratings from top-rated analysts.Filter, analyze, and streamline your search for investment opportunities with  TipRanks’ Stock Screener.Ionis Pharmaceuticals: Hold Rating Amid Revenue Growth, Competitive Pressures, and Delayed Catalysts. Ionis Pharmaceuticals: Balancing Strong R&D Revenues with Market Challenges – Hold Rating Justified","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/ionis-pharmaceuticals-price-target-lowered-143535885.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/ionis-pharmaceuticals-price-target-lowered-143535885.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["IONS","RJF"],"gpt_icon":0},{"id":"2513291467","title":"Pharma Stock Roundup: EU Nod to MRK's Welireg, IONS' Q4 Results & More","url":"https://stock-news.laohu8.com/highlight/detail?id=2513291467","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2513291467?lang=en_us&edition=fundamental","pubTime":"2025-02-21 21:41","pubTimestamp":1740145260,"startTime":"0","endTime":"0","summary":"This week, the European Commission granted approval to Merck’s MRK novel HIF-2α inhibitor, Welireg, for two indications. The FDA granted priority review to a supplemental biologics license application  seeking approval of Sanofi SNY and Regeneron’s REGN blockbuster drug, Dupixent, for a new indication, bullous pemphigoid. Ionis Pharmaceuticals IONS announced its fourth-quarter and full-year 2024 results.Here's a recap of the week’s most important stories.IONS reported better-than-expected top and bottom-line numbers for the fourth quarter. Its loss of 66 cents per share was narrower than the Zacks Consensus Estimate of a loss of $1.12 per share. Total revenues of $227 million beat the Zacks Consensus Estimate of $137.5 million. However, revenues declined 30.2% year over year. Commercial revenues were $86 million in the fourth quarter, up 8.9% year over year. R&D revenues declined 42.7% year over year to $141 million.EU Approval to Merck’s Welireg for Two Indications. The NYSE ARCA Phar","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/pharma-stock-roundup-eu-nod-134100358.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LU1934455194.USD","SG9999015358.SGD","SG9999014559.SGD","LU1585245621.USD","LU0070302665.USD","LU0965509101.SGD","LU0106261372.USD","LU1929549753.HKD","SG9999014542.SGD","IE00BLSP4452.SGD","IE00BBT3K403.USD","LU1162221912.USD","LU1430594728.SGD","LU1066051498.USD","LU0882574055.USD","LU2112291526.USD","LU2361045086.USD","BK4516","LU0053666078.USD","LU2023250843.SGD","REGN","LU2362541273.HKD","LU0985320562.USD","LU2361044949.HKD","LU0266013472.USD","LU0320765489.SGD","SG9999001176.USD","SG9999001440.SGD","LU0203345920.USD","LU0965509010.AUD","IE00B2B36J28.USD","SG9999014575.USD","BK4588","LU1934455863.HKD","LU1023059063.AUD","SNY","SG9999002232.USD","LU0965509283.SGD","IONS","BK4156","SGXZ57979304.SGD","LU0823416689.USD","LU1066051225.USD","LU1934455277.USD","BK4533","LU2237438978.USD","MRK","LU1061106388.HKD","SG9999013999.USD"],"gpt_icon":0},{"id":"2513344265","title":"Ionis Pharmaceuticals Inc : Bernstein Cuts Target Price to $43 From $51","url":"https://stock-news.laohu8.com/highlight/detail?id=2513344265","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2513344265?lang=en_us&edition=fundamental","pubTime":"2025-02-21 19:03","pubTimestamp":1740135834,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250221:nFWN3PC10J:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","IONS"],"gpt_icon":0},{"id":"2512449520","title":"BRIEF-New Positive Donidalorsen Data To Be Presented At 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