HUTCHMED launches Phase III China trial of HMPL-760 plus R-GemOx in relapsed/refractory DLBCL

Reuters

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HUTCHMED launches Phase III China trial of HMPL-760 plus R-GemOx in relapsed/refractory DLBCL

HUTCHMED initiated a registrational Phase III randomized, double-blind trial in China evaluating HMPL-760 plus R-GemOx versus placebo plus R-GemOx in patients with relapsed/refractory diffuse large B-cell lymphoma who are ineligible for transplantation.
The study plans to enroll about 240 patients and lists investigator-assessed progression-free survival and overall survival as the primary endpoints.
Secondary endpoints include independent review committee-assessed progression-free survival and objective response rate.
Earlier results from a randomized, double-blind Phase II study of HMPL-760 plus R-GemOx in the same setting were already presented, and those data supported initiation of the Phase III trial.
The Phase III trial is led by principal investigator Weili Zhao.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. HUTCHMED (China) Ltd. published the original content used to generate this news brief via GlobeNewswire (Ref. ID: 202603222000PRIMZONEFULLFEED9676085) on March 23, 2026, and is solely responsible for the information contained therein.

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