Nanjing Leads Biolabs Co. Ltd. reported that the first patient has been dosed in an open-label, multi-center Phase II clinical study of opamtistomig (LBL-024), a PD-L1/4-1BB bispecific antibody, as first-line treatment for locally advanced or metastatic esophageal squamous cell carcinoma in China. The study is led by Professor Shen Lin of Beijing Cancer Hospital and will assess the drug’s efficacy and safety across multiple hospitals. No trial results were presented in the announcement; results are expected to be reported in the future.
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