CervoMed Inc. announced completion of a Phase 1 healthy volunteer study evaluating the pharmacokinetics of a drug product containing a new, stable crystal form of neflamapimod and selected a 50 mg three-times-daily dosing regimen for its planned Phase 3 trial in patients with dementia with Lewy bodies. The company said the higher dose is intended to achieve plasma drug concentrations associated with therapeutic activity observed previously with a clinically active drug product batch used in the extension phase of the Phase 2b RewinD-LB trial. CervoMed stated that additional results and comparative pharmacokinetic data are being made available in its corporate presentation.
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