European equities traded in the US as American depositary receipts were marginally lower late Tuesday morning, edging 0.12% lower to 1,816.92 on the S&P Europe Select ADR Index.

From continental Europe, the gainers were led by lender Banco Santander (SAN) and biopharmaceutical company Cellectis (CLLS), which advanced 3.4% and 2.1%, respectively. They were followed by biopharmaceutical company Grifols (GRFS) and lender ING (ING), which increased 1.8% each.

The decliners from continental Europe were led by internet advertising firm Criteo (CRTO) and biotech company Evaxion (EVAX), which dropped 6.3% and 5.7%, respectively. They were followed by semiconductor company Sequans Communications (SQNS) and biopharmaceutical company DBV Technologies (DBVT), which lost 5.6% and 3.1%, respectively.

From the UK and Ireland, the gainers were led by biopharmaceutical companies Biodexa Pharmaceuticals (BDRX) and Akari Therapeutics (AKTX), which rose 15.5% and 5.8%, respectively. They were followed by pharmaceutical company GSK (GSK) and cruise line operator Carnival (CUK), which were up 2.9% and 2.4%, respectively.

The decliners from the UK and Ireland were led by communications company WPP (WPP) and biopharmaceutical company Bicycle Therapeutics (BCYC), which fell 4.1% and 3.2%, respectively. They were followed by hospitality company InterContinental Hotels Group (IHG) and alcoholic beverage company Diageo (DEO), which were down 2.2% and 1.8%, respectively.