Recasts first sentence with Gilead, adds details throughout on drugs, analyst comment, share prices, trade group comments, company comments
Fifteen drugs targeted for Medicare price negotiations in 2028
Industry opposes law, citing higher costs and fewer choices for seniors
Selected drugs accounted for $27 billion in spending, no generic alternatives
By Michael Erman and Deena Beasley
Jan 27 (Reuters) - The U.S. government on Tuesday named the 15 new drugs targeted for Medicare price negotiations for 2028, including Gilead Sciences' GILD.O HIV drug Biktarvy and Pfizer's PFE.N arthritis treatment Xeljanz.
It is the third round of drugs subject to former President Joe Biden's Inflation Reduction Act of 2022, which allowed the government to negotiate prices of some drugs purchased by the U.S. Medicare health program for people aged 65 and older or with disabilities.
Despite the industry's longstanding opposition to the law and multiple failed lawsuits, the first negotiated prices on 10 drugs sold in pharmacies went into effect this year.
The 2028 list also includes products that are administered in doctors' offices or hospitals, such as Novartis NOVN.S psoriasis drug Cosentyx and Botox, which is made by AbbVie ABBV.N.
Other medications up for negotiation include Eli Lilly's LLY.N GLP-1 diabetes drug Trulicity.
"With prior rounds of pricing negotiations reasonable, and several of these medicines set to lose exclusivity in the near-term, we continue to expect that the impacts will be manageable," said BMO Capital Markets analyst Evan Seigerman.
The U.S. Medicare health plan said last year that the prices it had negotiated for 15 drugs starting in 2027 would save the program 36% on those medications compared with recent annual spending, or about $8.5 billion.
Shares of Gilead, Lilly, AbbVie, Johnson & Johnson JNJ.N, Pfizer PFE.N and Bristol Myers BMY.N were all up nearly 2% in after-hours trading.
Gilead's HIV treatment Biktarvy, which had 2024 sales of $13.4 billion, had been expected to be on the negotiation list. The company in October said it had reached settlements with three generic manufacturers, extending the drug's U.S. patent coverage to April 2036.
"While we expect Biktarvy will likely be eligible for IRA price negotiations beginning in 2028, only a low-20% of US sales are expected to be exposed," JP Morgan said in a research note at that time.
The U.S. Centers for Medicaid and Medicare Services said the selected drugs accounted for $27 billion in spending in the 12 months ended October 31, 2025. The drugs are also selected based on being either seven or 11 years out from being approved by the U.S. Food and Drug Administration and for which there is no generic or biosimilar alternative.
Drugmakers have continued to contest the legislation in courts.
"The IRA continues to show why government price setting is the wrong approach for Americans," Elizabeth Carpenter, head of policy and research at trade group PhRMA, said in a statement. "Since the law took effect, seniors have faced higher costs, fewer choices and more barriers to care."
A Novartis spokesperson said its two drugs, Cosentyx for inflammatory diseases and Kisqali for breast cancer, bring significant value to patients and that the law allowing negotiation will have long-lasting consequences for patients.
CMS targets 15 new drugs for next Medicare price talks https://reut.rs/4bT7ksL
(Reporting by Deena Beasley in Los Angeles, Michael Erman in New Jersey and Siddhi Mahatole in Bengaluru; Editing by Alan Barona, Franklin Paul and Matthew Lewis)
((siddhi.mahatole@thomsonreuters.com;))