CytomX Therapeutics Inc. presented updates on its oncology pipeline at the 44th Annual JP Morgan Healthcare Conference. The company highlighted its PROBODY® platform, which focuses on masked therapeutics for targeted cancer treatment. Lead clinical programs include varsetatug masetecan (Varseta-M, formerly CX-2051), an EpCAM-directed antibody drug conjugate in Phase 1 trials for colorectal cancer, and CX-801 (PROBODY® IFN-α2b) for melanoma. Additional studies are planned, including combination therapies and expansion into other EpCAM-positive indications. CytomX also reported collaborations with Bristol Myers Squibb, Amgen, Astellas, Regeneron, and Moderna, and noted a cash runway into the second quarter of 2027. You can access the full presentation through the link below.
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