Amplia Therapeutics Reports Promising Phase 2a Trial Results for Narmafotinib in Pancreatic Cancer

Reuters

Jan 12

<a href="https://laohu8.com/S/ATX.AU">Amplia Therapeutics</a> Reports Promising Phase 2a Trial Results for Narmafotinib in Pancreatic Cancer

Amplia Therapeutics Ltd. has announced the presentation of interim data from its ongoing Phase 2a ACCENT trial in metastatic pancreatic cancer at the 2026 ASCO Gastrointestinal Cancer Symposium. The trial evaluates the efficacy and safety of Amplia’s FAK inhibitor, narmafotinib, in combination with standard chemotherapy. The updated data show a progression-free survival of 7.7 months compared to 5.5 months for gemcitabine and Abraxane alone. The overall response rate is reported at 35%, increasing to 42% when including unconfirmed responses. Narmafotinib was found to be well tolerated, with an adverse effect profile similar to chemotherapy alone. The results were shared in a poster presentation and a copy is available on the company’s website.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Amplia Therapeutics Ltd. published the original content used to generate this news brief via GlobeNewswire (Ref. ID: GNW9623643-en) on January 12, 2026, and is solely responsible for the information contained therein.

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The trial evaluates the efficacy and safety of Amplia’s FAK inhibitor, narmafotinib, in combination with standard chemotherapy. The updated data show a progression-free survival of 7.7 months compared to 5.5 months for gemcitabine and Abraxane alone. The overall response rate is reported at 35%, increasing to 42% when including unconfirmed responses. Narmafotinib was found to be well tolerated, with an adverse effect profile similar to chemotherapy alone. The results were shared in a poster presentation and a copy is available on the company’s website.\n      </p>\n</div><div xmlns:xsd=\"http://www.w3.org/2001/XMLSchema\" xmlns:xsi=\"http://www.w3.org/2001/XMLSchema-instance\">\n<p>\n<i>Disclaimer: <span>This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Amplia <a href=\"https://laohu8.com/S/LENZ\">Therapeutics</a> Ltd. published the original content used to generate this news brief via GlobeNewswire (Ref. 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The trial evaluates the efficacy and safety of Amplia’s FAK inhibitor, narmafotinib, in combination with standard chemotherapy. The updated data show a progression-free survival of 7.7 months compared to 5.5 months for gemcitabine and Abraxane alone. The overall response rate is reported at 35%, increasing to 42% when including unconfirmed responses. Narmafotinib was found to be well tolerated, with an adverse effect profile similar to chemotherapy alone. The results were shared in a poster presentation and a copy is available on the company’s website.\n      </p>\n</div><div xmlns:xsd=\"http://www.w3.org/2001/XMLSchema\" xmlns:xsi=\"http://www.w3.org/2001/XMLSchema-instance\">\n<p>\n<i>Disclaimer: <span>This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Amplia <a href=\"https://laohu8.com/S/LENZ\">Therapeutics</a> Ltd. published the original content used to generate this news brief via GlobeNewswire (Ref. ID: GNW9623643-en) on January 12, 2026, and is solely responsible for the information contained therein.</span></i>\n</p>\n</div></body></html>\n\n</article>\n</div>\n</body>\n</html>\n","isBrief":false,"type":0,"news_type":1,"symbol":"ATX.AU","symbol_name":"AMPLIA THERAPEUTICS LTD","start_time":0,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260112:nNDL2TLXkw:1","article_id":"2602543397","we_media_id":"1032215980","thumbnails":[],"rights":null,"url":"https://stock-news.laohu8.com/highlight/detail?id=2602543397","pubTimestamp":1768225509,"columns":[],"sourceInfo":null,"weMediaInfo":{"media_name":"Reuters","introduction":"Reuters.com brings you the latest news from around the world, covering breaking news in markets, business, politics, entertainment and technology","home_visible":1,"id":"1032215980","head_image":"https://community-static.tradeup.com/news/4567337cbdf294b657b1fa87c5488b48"},"summary":"Amplia Therapeutics Ltd. has announced the presentation of interim data from its ongoing Phase 2a ACCENT trial in metastatic pancreatic cancer at the 2026 ASCO Gastrointestinal Cancer Symposium. 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The trial evaluates the efficacy and safety of Amplia’s FAK inhibitor, narmafotinib, in combination with standard chemotherapy. The updated data show a progression-free survival of 7.7 months compared to 5.5 months for gemcitabine and Abraxane alone. The overall response rate is reported at 35%, increasing to 42% when including unconfirmed responses. Narmafotinib was found to be well tolerated, with an adverse effect profile similar to chemotherapy alone. The results were shared in a poster presentation and a copy is available on the company’s website.\n      \n\n\nDisclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Amplia Therapeutics Ltd. published the original content used to generate this news brief via GlobeNewswire (Ref. 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