Nyrada (ASX:NYR) received approval from the Human Research Ethics Committee to start the Phase IIa clinical randomised, double-blind, placebo-controlled, multicenter trial of its small-molecule inhibitor Xolatryp in the treatment of myocardial ischemia reperfusion injury in patients suffering a heart attack, according to a Thursday filing with the Australian bourse.
The trial will evaluate the safety and preliminary efficacy of Xolatryp in treating the injury in about 200 patients, the filing said.
It will also evaluate multiple secondary efficacy signals, including cardiac function and extent of cardiac injury, the filing added.
The company expects to start patient recruitment and dosing in March for the trial, the filing added.
It expects to complete the trial within 18 months after the patient is dosed.
Shares of the company rose 2% in recent Thursday trade.