(Updates with the latest stock price movement in the headline and the first paragraph.)
Edgewise Therapeutics (EWTX) shares rose 20% in recent Wednesday trading after the company said it completed parts B and C of a phase 2 trial of EDG-7500 in patients with obstructive and nonobstructive hypertrophic cardiomyopathy and reported favorable interim safety results from its ongoing part D study.
The company said EDG-7500 was generally well tolerated with no clinically meaningful reductions in left ventricular ejection fraction and no cases of ejection fraction drops below 50%.
Edgewise Therapeutics said it remains on track to report a full 12-week readout from part D in Q2 2026 and plans to initiate a phase 3 trial in Q4 2026.
Hypertrophic cardiomyopathy is a form of genetic heart disease.
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