CalciMedica Launches Phase 2 KOURAGE Trial of Auxora in Acute Kidney Injury with Respiratory Failure

Reuters

Nov 12

CalciMedica Launches Phase 2 KOURAGE Trial of Auxora in Acute Kidney Injury with Respiratory Failure

CalciMedica Inc. has announced ongoing enrollment in its Phase 2 KOURAGE trial, evaluating Auxora™ in patients with Stage 2 or Stage 3 acute kidney injury (AKI) with respiratory failure. The company plans to enroll 150 patients, with data expected in the first half of 2026. Additionally, CalciMedica reported positive discussions with the U.S. Food and Drug Administration (FDA) regarding the design of a pivotal trial in acute pancreatitis $(AP)$, with final trial design anticipated in the first half of 2026. In November 2025, preclinical results on Auxora were presented at the American Society of Nephrology (ASN) Kidney Week, showing improved kidney function and reduced renal injury in a rat model of AKI. CalciMedica has also entered a collaboration with Telperian to utilize AI insights in support of its AP pivotal trial design.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. CalciMedica Inc. published the original content used to generate this news brief via PR Newswire (Ref. ID: LA21933) on November 12, 2025, and is solely responsible for the information contained therein.

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The company plans to enroll 150 patients, with data expected in the first half of 2026. Additionally, CalciMedica reported positive discussions with the U.S. Food and Drug Administration (FDA) regarding the design of a pivotal trial in acute pancreatitis <a href=\"https://laohu8.com/S/AP\">$(AP)$</a>, with final trial design anticipated in the first half of 2026. In November 2025, preclinical results on Auxora were presented at the American Society of Nephrology (ASN) Kidney Week, showing improved kidney function and reduced renal injury in a rat model of AKI. CalciMedica has also entered a collaboration with Telperian to utilize AI insights in support of its AP pivotal trial design.\n      </p>\n</div><div xmlns:xsd=\"http://www.w3.org/2001/XMLSchema\" xmlns:xsi=\"http://www.w3.org/2001/XMLSchema-instance\">\n<em>Disclaimer: <span>This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. CalciMedica Inc. published the original content used to generate this news brief via PR Newswire (Ref. ID: LA21933) on November 12, 2025, and is solely responsible for the information contained therein.</span></em>\n</div></body></html>\n\n</article>\n</div>\n</body>\n</html>\n","isBrief":false,"type":0,"news_type":1,"symbol":"BK4007","symbol_name":"制药","start_time":0,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251112:nNDL2Gz9x9:1","article_id":"2582373023","we_media_id":"1032215980","thumbnails":[],"rights":null,"url":"https://stock-news.laohu8.com/highlight/detail?id=2582373023","pubTimestamp":1762948973,"columns":[],"sourceInfo":null,"weMediaInfo":{"media_name":"Reuters","introduction":"Reuters.com brings you the latest news from around the world, covering breaking news in markets, business, politics, entertainment and technology","home_visible":1,"id":"1032215980","head_image":"https://community-static.tradeup.com/news/4567337cbdf294b657b1fa87c5488b48"},"summary":"CalciMedica Inc. has announced ongoing enrollment in its Phase 2 KOURAGE trial, evaluating Auxora in patients with Stage 2 or Stage 3 acute kidney injury  with respiratory failure. The company plans to enroll 150 patients, with data expected in the first half of 2026. Additionally, CalciMedica reported positive discussions with the U.S. Food and Drug Administration  regarding the design of a pivotal trial in acute pancreatitis , with final trial design anticipated in the first half of 2026. In November 2025, preclinical results on Auxora were presented at the American Society of Nephrology  Kidney Week, showing improved kidney function and reduced renal injury in a rat model of AKI. CalciMedica has also entered a collaboration with Telperian to utilize AI insights in support of its AP pivotal trial design.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. 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