Estrella Immunopharma Inc. announced the successful completion of the second dose cohort in the Phase I portion of its STARLIGHT-1 Phase I/II clinical trial evaluating EB103, a CD19-redirected ARTEMIS® T-cell therapy for patients with advanced B-cell Non-Hodgkin's Lymphomas (NHL). According to the company, all evaluable patients in this high-risk group-including those not suitable for commercial CD19 products and one with central nervous system involvement-achieved a 100% complete response rate at Month 1. No treatment-related serious adverse events were reported in this cohort. The results have been announced by the company, and a Data and Safety Monitoring Board will review the cumulative study data to determine the recommended Phase II dose for the trial's expansion phase. Further details are available under clinical trial identifier NCT06343311.
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