Small U.S. Stocks Close Lower; WAVE Life Sciences Takes Biggest Hit

Dow Jones
Sep 04

This article was automatically generated using Dow Jones technology.

Shares of small-cap companies declined Wednesday, as the Russell 2000 Index declined 0.1%, and the S&P Small Cap 600 Index was down 0.1%.

Among companies with a market value of $1 billion to $6.7 billion, WAVE Life Sciences Ltd. was the biggest laggard during the session, dropping 17%, followed by shares of Bruker Corp., which dropped 12%. Shares of Sprinklr Inc. Cl A dropped 10%, Solaris Energy Infrastructure Inc. shares tumbled 9.7%, and Inspire Medical Systems Inc. plunged 9.4%.

Macy's Inc. was the best performer, surging 21%, followed by Beam Therapeutics Inc., which jumped 15%. REV Group Inc. shares surged 13%, Immunovant Inc. jumped 11%, and shares of Cogent Biosciences Inc. surged 9.0%.

Major stock indexes in the U.S. ended Wednesday mixed as the Nasdaq Composite Index gained 1.0%. Meanwhile, the S&P 500 Index added 0.5%, and the Dow Jones Industrial Average declined 0.1%.

Data source: Dow Jones Market Data, FactSet

 

(END) Dow Jones Newswires

September 03, 2025 16:20 ET (20:20 GMT)

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