GUANGZHOU, China, June 06, 2025 (GLOBE NEWSWIRE) -- Burning Rock Biotech Limited (NASDAQ: BNR, the "Company" or "Burning Rock"), a company focused on the application of next generation sequencing $(NGS)$ technology in the field of precision oncology, today reported financial results for the three months ended March 31, 2025.
Recent Business Updates
-- Therapy Selection and MRD
-- Personalized Minimal Residual Disease $(MRD.AU)$ product, CanCatch$(R)$
Custom supports advancement in oesophageal squamous cell carcinoma
OSCC treatment, with results published in the Molecular Cancer in
May 2025. The study is a two-arm, multicenter, randomized,
double-blind phase 2 study, comparing the efficacy of systemic
treatment combining nCT with immunotherapy against nCT alone for
OSCC patients. The study demonstrates that Perioperative Nivolumab
plus chemotherapy is a viable and safe option for systemically
treating locally advanced resectable OSCC, and monitoring minimal
residual disease through ctDNA could be potentially valuable for
assessing the effectiveness of adjuvant therapy and for prognostic
evaluation in a systemic manner.
-- Presented study results on non-small cell lung cancer and
gastrointestinal stromal tumor (GIST) at the ASCO in June 2025.
"Personalized tumor-informed ctDNA has the potential to inform
recurrence in high-risk locally advanced stage GIST patients,
especially for patients with irregular adjuvant therapy" and
"MUSETALK-Lung01 (MUltiomics SEquencing Technique AppLication
Kick-start) is a prospective, longitudinal, observational study
designed to evaluate the clinical utility of a tumor-naïve
ctDNA assay in patients with early-stage non-small cell lung
cancer (NSCLC)."
-- Presented multiple study results at the 2025 AACR in April,
showcasing the clinical utility of the tumor-informed personalized
MRD assay (CanCatch(R) Custom) and the tumor-naïve
methylation-based MRD assay.
First Quarter 2025 Financial Results
Revenues were RMB133.1 million (US$18.3 million) for the three months ended March 31, 2025, representing a 5.9% increase from RMB125.6 million for the same period in 2024.
-- Revenue generated from central laboratory business was RMB38.3 million
(US$5.3 million) for the three months ended March 31, 2025, representing
a 19.6% decrease from RMB47.6 million for the same period in 2024,
primarily attributable to a decrease in the number of tests, as we
continued to focus on our in-hospital business.
-- Revenue generated from in-hospital business was RMB57.7 million (US$7.9
million) for the three months ended March 31, 2025, representing a 0.5%
increase from RMB57.4 million for the same period in 2024, driven by a
continuous growth in sales volume.
-- Revenue generated from pharma research and development services was
RMB37.1 million (US$5.1 million) for the three months ended March 31,
2025, representing a 79.9% increase from RMB20.6 million for the same
period in 2024, primarily attributable to increased development and
testing services performed for our pharma customers, and several
milestones of our pharma programs were achieved.
Cost of revenues was RMB35.7 million (US$4.9 million) for the three months ended March 31, 2025, representing a 10.6% decrease from RMB39.9 million for the same period in 2024, primarily due to a decrease in cost of central laboratory business, which was in line with the decrease in revenue generated from this business.
Gross profit was RMB97.4 million (US$13.4 million) for the three months ended March 31, 2025, representing a 13.7% increase from RMB85.7 million for the same period in 2024. Gross margin was 73.2% for the three months ended March 31, 2025, compared to 68.2% for the same period in 2024. By channel, gross margin of central laboratory business was 84.1% for the three months ended March 31, 2025, compared to 77.7% during the same period in 2024, primarily due to a reduction in material and labor costs resulted from cost optimization and control measures and a decreased depreciation and rental cost in relation to our laboratory of Guangzhou headquarter; gross margin of in-hospital business was 76.1% for the three months ended March 31, 2025, compared to 68.3% during the same period in 2024, primarily due to the same reason; gross margin of pharma research and development services was 57.5% for the three months ended March 31, 2025, compared to 46.1% during the same period of 2024, primarily due to the cost optimization measures and an increase in test volume of higher margin projects.
Non-GAAP gross profit, which excludes depreciation and amortization expenses, RMB100.7 million (US$13.9 million) for the three months ended March 31, 2025, representing an 8.3% increase from RMB93.0 million for the same period in 2024. Non-GAAP gross margin was 75.6% for the three months ended March 31, 2025, compared to 74.0% for the same period in 2024.
Operating expenses were RMB112.6 million (US$15.5 million) for the three months ended March 31, 2025, representing a 46.8% decrease from RMB211.5 million for the same period in 2024. The decrease was primarily driven by budget control measures and headcount reduction to improve the Company's operating efficiency.
-- Research and development expenses were RMB40.4 million (US$5.6 million)
for the three months ended March 31, 2025, representing a 38.8% decrease
from RMB66.0 million for the same period in 2024, primarily due to (i) a
decrease in amortized expense on share-based compensation; (ii) a
decrease in the expenditure for detection research and (iii) a decrease
in depreciation and amortization.
-- Selling and marketing expenses were RMB40.9 million (US$5.6 million) for
the three months ended March 31, 2025, representing a 12.7% decrease from
RMB46.9 million for the same period in 2024, primarily due to (i) a
decrease in staff cost resulted from the reorganization of our sales
department to improve operating efficiency and (ii) a decrease in
depreciation and amortization.
-- General and administrative expenses were RMB31.3 million (US$4.3 million)
for the three months ended March 31, 2025, representing a 68.3% decrease
from RMB98.7 million for the same period in 2024, primarily due to (i) a
decrease in amortized expense on share-based compensation; (ii) a
decrease in depreciation and amortization; (iii) a decrease in staff cost
resulted from the reorganization; and (iv) a decrease in operating lease
expense for office building.
Net loss was RMB13.5 million (US$1.9 million) for the three months ended March 31, 2025, compared to RMB121.5 million for the same period in 2024.
Cash, cash equivalents and restricted cash were RMB497.4 million (US$68.5 million) as of March 31, 2025.
Exchange Rate Information
This press release contains translations of certain Renminbi amounts into U.S. dollars at a specified rate solely for the convenience of the reader. Unless otherwise noted, all translations from Renminbi to U.S. dollars and from U.S. dollars to Renminbi are made at a rate of RMB7.2567 to US$1.00, the exchange rate on March 31, 2025, set forth in the H.10 statistical release of the Federal Reserve Board. The Company makes no representation that the Renminbi or U.S. dollars amounts referred could be converted into U.S. dollars or Renminbi, as the case may be, at any particular rate or at all.
About Burning Rock
Burning Rock Biotech Limited $(BNR)$, whose mission is to guard life via science, focuses on the application of next generation sequencing $(NGS.AU)$ technology in the field of precision oncology. Its business consists of i) NGS-based therapy selection testing for late-stage cancer patients, and ii) cancer early detection, which has moved beyond proof-of-concept R&D into the clinical validation stage.
For more information about Burning Rock, please visit: ir.brbiotech.com.
Safe Harbor Statement
This press release contains forward-looking statements. These statements constitute "forward-looking" statements within the meaning of Section 21E of the Securities Exchange Act of 1934, as amended, and as defined in the U.S. Private Securities Litigation Reform Act of 1995. These forward-looking statements can be identified by terminology such as "will," "expects," "anticipates," "future," "intends," "plans," "believes," "estimates," "target," "confident" and similar statements. Burning Rock may also make written or oral forward-looking statements in its periodic reports to the SEC, in its annual report to shareholders, in press releases and other written materials and in oral statements made by its officers, directors or employees to third parties. Statements that are not historical facts, including statements about Burning Rock's beliefs and expectations, are forward-looking statements. Such statements are based upon management's current expectations and current market and operating conditions, and relate to events that involve known or unknown risks, uncertainties and other factors, all of which are difficult to predict and many of which are beyond Burning Rock's control. Forward-looking statements involve risks, uncertainties and other factors that could cause actual results to differ materially from those contained in any such statements. All information provided in this press release is as of the date of this press release, and Burning Rock does not undertake any obligation to update any forward-looking statement as a result of new information, future events or otherwise, except as required under applicable law.
Non-GAAP Measures
In evaluating the business, the Company considers and uses non-GAAP measures, such as non-GAAP gross profit and non-GAAP gross margin, as supplemental measures to review and assess operating performance. The presentation of these non-GAAP financial measures is not intended to be considered in isolation or as a substitute for the financial information prepared and presented in accordance with accounting principles generally accepted in the United States of America ("U.S. GAAP"). The company defines non-GAAP gross profit as gross profit excluding depreciation and amortization. The company defines non-GAAP gross margin as gross margin excluding depreciation and amortization.
The company presents these non-GAAP financial measures because they are used by management to evaluate operating performance and formulate business plans. The company believe non-GAAP gross profit and non-GAAP gross margin excluding non-cash impact of depreciation and amortization reflect the company's ongoing business operations in a manner that allows more meaningful period-to-period comparisons.
Contact: IR@brbiotech.com
Selected Operating Data
As of
-------------------------------------------------------
March 31, June 30, September December March 31,
2024 2024 30, 2024 31, 2024 2025
--------- -------- ---------- ----------- ---------
In-hospital
Channel:
Pipeline
partner
hospitals(1) 28 29 30 29 30
Contracted
partner
hospitals(2) 59 59 61 63 63
Total number
of partner
hospitals 87 88 91 92 93
(1) Refers to hospitals that are in the process of establishing
in-hospital laboratories, laboratory equipment procurement
or installation, staff training or pilot testing using
the Company's products.
(2) Refers to hospitals that have entered into contracts
to purchase the Company's products for use on a recurring
basis in their respective in-hospital laboratories
the Company helped them establish. Kit revenue is
generated from contracted hospitals.
Selected Financial Data
For the three months ended
--------------------------------------------------------
March 31, June 30, September December March 31,
Revenues 2024 2024 30, 2024 31, 2024 2025
--------- -------- ----------- ----------- ---------
(RMB in thousands)
Central
laboratory
channel 47,614 48,773 39,984 39,278 38,296
In-hospital
channel 57,387 59,872 63,769 43,464 57,687
Pharma
research
and
development
channel 20,622 26,888 24,891 43,280 37,099
Total
revenues 125,623 135,533 128,644 126,022 133,082
For the three months ended
--------------------------------------------------------
March 31, June 30, September December March 31,
Gross profit 2024 2024 30, 2024 31, 2024 2025
--------- -------- ----------- ----------- ---------
(RMB in thousands)
Central
laboratory
channel 37,002 38,424 33,262 33,153 32,191
In-hospital
channel 39,192 44,058 46,580 29,563 43,895
Pharma
research
and
development
channel 9,500 12,956 12,004 26,706 21,315
Total gross
profit 85,694 95,438 91,846 89,422 97,401
For the three months ended
-----------------------------------------------------
Share-based
compensation March 31, June 30, September December March 31,
expenses 2024 2024 30, 2024 31, 2024 2025
--------- -------- --------- ---------- ---------
(RMB in thousands)
Cost of
revenues 596 464 289 520 308
Research and
development
expenses 12,287 12,008 3,180 3,202 1,800
Selling and
marketing
expenses 508 1,232 1,917 1,353 1,025
General and
administrative
expenses 55,990 54,407 4,732 2,937 1,413
Total
share-based
compensation
expenses 69,381 68,111 10,118 8,012 4,546
Burning Rock Biotech Limited
Unaudited Condensed Statements of Comprehensive Loss
(in thousands, except for number of shares and per share data)
For the three months ended
------------------------------------------------------------------------------
March 31, June 30, September December March 31, March 31,
2024 2024 30, 2024 31, 2024 2025 2025
----------- ----------- ----------- ----------- ----------- -------------
RMB RMB RMB RMB RMB US$
Revenues 125,623 135,533 128,644 126,022 133,082 18,340
Cost of
revenues (39,929) (40,095) (36,798) (36,600) (35,681) (4,918)
---------- ---------- ---------- ---------- ---------- ----------
Gross profit 85,694 95,438 91,846 89,422 97,401 13,422
Operating
expenses:
Research and
development
expenses (65,985) (64,952) (49,150) (52,203) (40,389) (5,566)
Selling and
marketing
expenses (46,856) (48,907) (48,411) (46,730) (40,888) (5,635)
General and
administrative
expenses (98,681) (92,794) (32,874) (37,289) (31,303) (4,314)
Impairment loss
on long-lived
assets (35,127)
---------- ---------- ---------- ---------- ---------- ----------
Total operating
expenses (211,522) (206,653) (130,435) (171,349) (112,580) (15,515)
---------- ---------- ---------- ---------- ---------- ----------
Loss from
operations (125,828) (111,215) (38,589) (81,927) (15,179) (2,093)
Interest income 4,038 3,187 3,173 1,814 2,581 356
Other income
(expense),
net 434 (82) 1 4,353 (652) (90)
Foreign
exchange
(loss) gain,
net (13) 262 (129) (220) (26) (4)
---------- ---------- ---------- ---------- ---------- ----------
Loss before
income tax (121,369) (107,848) (35,544) (75,980) (13,276) (1,831)
Income tax
expenses (180) (190) (201) (5,314) (224) (31)
---------- ---------- ---------- ---------- ---------- ----------
Net loss (121,549) (108,038) (35,745) (81,294) (13,500) (1,862)
========== ========== ========== ========== ========== ==========
Net loss
attributable
to Burning
Rock Biotech
Limited's
shareholders (121,549) (108,038) (35,745) (81,294) (13,500) (1,862)
Net loss
attributable
to ordinary
shareholders (121,549) (108,038) (35,745) (81,294) (13,500) (1,862)
Loss per share
for class A and
class B
ordinary
shares:
Class A
ordinary
shares - basic
and diluted (1.19) (1.05) (0.35) (0.79) (0.13) (0.02)
Class B
ordinary
shares - basic
and diluted (1.19) (1.05) (0.35) (0.79) (0.13) (0.02)
Weighted
average shares
outstanding
used in loss
per share
computation:
Class A
ordinary
shares - basic
and diluted 85,219,188 85,271,858 85,902,670 86,036,286 90,291,658 90,291,658
Class B
ordinary
shares - basic
and diluted 17,324,848 17,324,848 17,324,848 17,324,848 17,324,848 17,324,848
Other
comprehensive
income (loss),
net of tax of
nil:
Foreign
currency
translation
adjustments 590 940 (4,054) 6,009 (72) (10)
Total
comprehensive
loss (120,959) (107,098) (39,799) (75,285) (13,572) (1,872)
Total
comprehensive
loss
attributable
to Burning
Rock Biotech
Limited's
shareholders (120,959) (107,098) (39,799) (75,285) (13,572) (1,872)
Burning Rock Biotech Limited
Unaudited Condensed Consolidated Balance Sheets
(In thousands)
As of
December 31, March 31, March 31,
2024 2025 2025
------------ --------- ---------
RMB RMB US$
ASSETS
Current assets:
Cash and cash equivalents 519,849 495,145 68,233
Restricted cash 2,313 2,261 312
Accounts receivable, net 152,013 159,463 21,974
Contract assets, net 13,855 17,178 2,367
Inventories, net 62,625 65,424 9,016
Prepayments and other current assets,
net 25,963 22,072 3,042
------------ --------- ---------
Total current assets 776,618 761,543 104,944
------------ --------- ---------
Non-current assets:
Property and equipment, net 47,152 41,162 5,672
Operating right-of-use assets 53,188 43,804 6,036
Intangible assets, net 421 386 53
Other non-current assets 7,926 7,822 1,078
------------ --------- ---------
Total non-current assets 108,687 93,174 12,839
------------ --------- ---------
TOTAL ASSETS 885,305 854,717 117,783
============ ========= =========
Burning Rock Biotech Limited
Unaudited Condensed Consolidated Balance Sheets (Continued)
(in thousands)
As of
December 31, March 31, March 31,
2024 2025 2025
------------ ----------- -----------
RMB RMB US$
LIABILITIES AND SHAREHOLDERS'
EQUITY
Current liabilities:
Accounts payable 33,747 35,938 4,952
Deferred revenue 117,895 117,200 16,151
Accrued liabilities and other
current liabilities 89,498 76,198 10,501
Customer deposits 592 592 82
Current portion of operating
lease liabilities 24,567 22,524 3,104
----------- ---------- --------
Total current liabilities 266,299 252,452 34,790
----------- ---------- --------
Non-current liabilities:
Non-current portion of
operating lease liabilities 27,754 19,814 2,730
Other non-current liabilities 10,425 10,649 1,467
----------- ---------- --------
Total non-current liabilities 38,179 30,463 4,197
----------- ---------- --------
TOTAL LIABILITIES 304,478 282,915 38,987
=========== ========== ========
Shareholders' equity:
Class A ordinary shares 124 124 17
Class B ordinary shares 21 21 3
Additional paid-in capital 5,002,255 5,005,991 689,844
Treasury stock (63,264) (62,453) (8,606)
Accumulated deficits (4,200,261) (4,213,761) (580,672)
Accumulated other
comprehensive loss (158,048) (158,120) (21,790)
----------- ---------- --------
Total shareholders' equity 580,827 571,802 78,796
----------- ---------- --------
TOTAL LIABILITIES AND
SHAREHOLDERS' EQUITY 885,305 854,717 117,783
=========== ========== ========
Burning Rock Biotech Limited
Unaudited Condensed Statements of Cash Flows
(in thousands)
For the three months ended
March 31, March 31, March 31,
2024 2025 2025
------------- --------- -----------
RMB RMB US$
Net cash generated from (used in)
operating activities 19,062 (23,527) (3,242)
Net cash used in investing
activities (812) (1,531) (211)
Net cash used in financing
activities (74) - -
Effect of exchange rate on cash,
cash equivalents and restricted
cash 5,739 302 43
Net increase in (decrease) cash,
cash equivalents and restricted
cash 23,915 (24,756) (3,410)
Cash, cash equivalents and
restricted cash at the beginning
of period 498,247 522,162 71,955
Cash, cash equivalents and
restricted cash at the end of
period 522,162 497,406 68,545
Burning Rock Biotech Limited
Reconciliations of GAAP and Non-GAAP Results
For the three months ended
--------- -------------------------------------------
March 31, June 30, September December March 31,
2024 2024 30, 2024 31, 2024 2025
--------- -------- ---------- ---------- ---------
(RMB in thousands)
Gross profit:
Central
laboratory
channel 37,002 38,424 33,262 33,153 32,191
In-hospital
channel 39,192 44,058 46,580 29,563 43,895
Pharma
research and
development
channel 9,500 12,956 12,004 26,706 21,315
Total gross
profit 85,694 95,438 91,846 89,422 97,401
Add:
depreciation
and
amortization:
Central
laboratory
channel 1,919 1,226 1,277 1,010 562
In-hospital
channel 1,524 824 798 623 290
Pharma
research and
development
channel 3,856 4,417 3,846 2,534 2,412
Total
depreciation
and
amortization
included in
cost of
revenues 7,299 6,467 5,921 4,167 3,264
Non-GAAP gross
profit
Central
laboratory
channel 38,921 39,650 34,539 34,163 32,753
In-hospital
channel 40,716 44,882 47,378 30,186 44,185
Pharma
research and
development
channel 13,356 17,373 15,850 29,240 23,727
Total non-GAAP
gross profit 92,993 101,905 97,767 93,589 100,665
Non-GAAP gross
margin
Central
laboratory
channel 81.7% 81.3% 86.4% 87.0% 85.5%
In-hospital
channel 70.9% 75.0% 74.3% 69.5% 76.6%
Pharma
research and
development
channel 64.8% 64.6% 63.7% 67.6% 64.0%
Total non-GAAP
gross margin 74.0% 75.2% 76.0% 74.3% 75.6%
(END) Dow Jones Newswires
June 06, 2025 03:31 ET (07:31 GMT)
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