Relay Therapeutics Inc., a clinical-stage precision medicine company, has announced updated interim clinical data for their investigational drug RLY-2608. Presented at the American Society of Clinical Oncology (ASCO) 2025 Annual Meeting, the data demonstrates a median progression-free survival $(PFS)$ of 11.0 months in second-line patients with PI3Kα-mutated, HR+, HER2- metastatic breast cancer who were treated with RLY-2608 in combination with fulvestrant. The company also announced plans to initiate a Phase 3 trial, named ReDiscover-2, in mid-2025. This trial will focus on patients with similar cancer profiles. Relay Therapeutics continues to explore next-generation triplet combinations involving atirmociclib and ribociclib. Further details on the data and upcoming trials are available on the company's website.
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