SBP GROUP (01177): Lixin Pharma Presents Preliminary Clinical Data for MK-2010/LM-299 at AACR 2026

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SBP GROUP (01177) has announced that its wholly-owned subsidiary, Lixin Pharmaceutical Technology (Shanghai) Co., Ltd. ("Lixin Pharma"), has released initial clinical data for its self-developed innovative drug MK-2010/LM-299, a PD-1/VEGF bispecific antibody, at the 2026 American Association for Cancer Research (AACR) Annual Meeting. In November 2024, Lixin Pharma entered into a global exclusive licensing agreement with Merck & Co., known as MSD outside the United States and Canada, granting MSD exclusive rights to develop, produce, and commercialize LM-299 worldwide. MK-2010/LM-299 is an investigational tetravalent bispecific antibody that simultaneously targets programmed cell death protein-1 (PD-1) and vascular endothelial growth factor (VEGF). It utilizes an IgG-VHH fusion structure with Fcγ silencing functionality. Therapeutic strategies combining PD-1 inhibition with VEGF blockade, whether through co-administration or bispecific antibodies, have demonstrated clinical efficacy in various advanced solid tumors.

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