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Neurocrine Biosciences

126.55

-0.7600-0.60%

Post-market: 126.550.00000.00%17:01 EDT

Volume:1.58M

Turnover:199.40M

Market Cap:12.52B

PE:42.79

High:128.38

Open:127.88

Low:125.53

Close:127.31

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Overview Company News Filings

UBS Lowers Price Target on Neurocrine Biosciences to $137 From $154, Keeps Buy Rating

MT Newswires Live

RBC Trims Price Target on Neurocrine Biosciences to $138 From $139, Keeps Sector Perform Rating

MT Newswires Live

Neurocrine Biosciences Presents Real-World Data on Therapeutic Dose Attainment and Dosing Trends of VMAT2 Inhibitors in Patients With Tardive Dyskinesia

Neurocrine Is Maintained at Overweight by JP Morgan

U.S. RESEARCH ROUNDUP-Ashland, Connectone Bancorp, Neurocrine Biosciences

Neurocrine’s ingrezza shows efficacy in tardive dyskinesia study

Neurocrine Biosciences Presents 48-Week Remission Data on Treatment of Tardive Dyskinesia With INGREZZA® (valbenazine) Capsules

Is Neurocrine Biosciences, Inc. (NBIX) a Best Biotech Stock According to Billionaires?

Neurocrine presents new KINECT-HD data

Big Pharma Walked Away From Mental Health. Why Some Are Coming Back. -- Heard on the Street -- WSJ

Neurocrine Biosciences to Present at the Stifel 2025 Virtual CNS Forum

RBC Cuts Price Target on Neurocrine Biosciences to $139 From $148, Keeps Sector Perform Rating

MT Newswires Live

BUZZ-Morgan Stanley initiates Crinetics with 'outperform' on catalyst rich 2025

Neurocrine Coverage Assumed by Morgan Stanley at Overweight

Positive Growth Outlook for Neurocrine Biosciences Driven by Ingrezza and Crenessity Sales Projections

Neurocrine Biosciences (NasdaqGS:NBIX) Begins Phase 1 Study Of New VMAT2 Inhibitor For Neurological Conditions

Simply Wall St.

BRIEF-Neurocrine Biosciences Announces Initiation Of Phase 1 Clinical Study Evaluating NBI-1140675

Neurocrine begins Phase 1 clinical study of NBI-1140675

Neurocrine Biosciences Announces Initiation of Phase 1 Clinical Study Evaluating Nbi-1140675, a Second-Generation Vmat2 Inhibitor, in Healthy Adults

THOMSON REUTERS

Neurocrine Biosciences Announces Initiation of Phase 1 Clinical Study Evaluating NBI-1140675, a Second-Generation VMAT2 Inhibitor, in Healthy Adults

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Findings Presented at the Academy of Managed Care Pharmacy 2025 Annual Meeting. SAN DIEGO, March 31, 2025 /PRNewswire/ -- Neurocrine Biosciences, Inc. today announced the presentation of new data from a real-world study showing that all patients with tardive dyskinesia achieved a therapeutic dose with INGREZZA  capsules upon initiation of treatment. This retrospective cohort study will be presented at the Academy of Managed Care Pharmacy 2025 Annual Meeting in Houston, Texas.\"These findings provide critical insights into the real-world use of VMAT2 inhibitors in treating tardive dyskinesia,\" said Eiry W. Roberts, M.D., Chief Medical Officer, Neurocrine Biosciences. \"Significant differences were observed between INGREZZA and deutetrabenazine in reaching therapeutic doses. 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Findings Presented at the 2025 Psychiatry Update Conference. SAN DIEGO, March 20, 2025 /PRNewswire/ -- Neurocrine Biosciences, Inc. today presented new data from the long-term, open-label KINECT 4 study demonstrating remission of tardive dyskinesia among the majority of patients treated with once-daily INGREZZA  capsules. This analysis was presented at the 2025 Psychiatry Update Conference in Chicago.\"These findings further establish INGREZZA as a highly effective long-term treatment option for individuals living with tardive dyskinesia, regardless of their underlying psychiatric condition, including schizophrenia, schizoaffective disorder or mood disorder,\" said Eiry W. Roberts, M.D., Chief Medical Officer, Neurocrine Biosciences. \"The significant improvements observed in AIMS score and the high remission rates highlight the efficacy of INGREZZA, at e","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/neurocrine-biosciences-presents-48-week-123000532.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/neurocrine-biosciences-presents-48-week-123000532.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4139","BK4581","LU0943347566.SGD","IE00B1XK9C88.USD","LU0820561818.USD","LU0942090050.USD","LU0889565916.HKD","IE00BWXC8680.SGD","BK4533","LU0320765992.SGD","LU1035775433.USD","LU0234572021.USD","LU0079474960.USD","BK4207","BK4567","LU0868494708.USD","LU1674673428.USD","LU0109394709.USD","BK4534","LU1093756168.USD","LU0823411888.USD","IE00BSNM7G36.USD","LU0823434740.USD","LU1093756325.SGD","LU2756315664.SGD","LU1496350502.SGD","LU0820562030.AUD","LU0320765646.SGD","LU0820561909.HKD","LU1778281490.HKD","LU2756315318.SGD","NBIX","LU2065171402.SGD","IE00BZ1G4Q59.USD","LU1496350171.SGD","LU2065170008.USD","LU2065169927.USD","TD","IE00BKVL7J92.USD","LU0823434583.USD","BK4083","LU2065171311.SGD","LU0689472784.USD","LU0354030438.USD","LU1989772840.SGD","NMS","LU1674673691.USD","LU1551013425.SGD","LU1162221912.USD","HD"],"gpt_icon":0},{"id":"2520650633","title":"Is Neurocrine Biosciences, Inc. 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Over the past quarter or two, though, that tendency has begun to improve.Flood’s report also emphasized how the biotech sector has recently demonstrated better fundamentals, which have been ascribed to superior clinical outcomes and a more favorable regulatory environment. Goldman’s data shows that hedge funds continue to underinvest in biotechnology despite these tailwinds. 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Why Some Are Coming Back. -- Heard on the Street -- WSJ","url":"https://stock-news.laohu8.com/highlight/detail?id=2519878426","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2519878426?lang=en_us&edition=fundamental","pubTime":"2025-03-14 17:30","pubTimestamp":1741944600,"startTime":"0","endTime":"0","summary":"Modern society's relationship with mental health has evolved in recent decades. Once taboo, conditions such as depression and bipolar disorder are now openly discussed by high-profile figures like Simone Biles and Mariah Carey. Governments and employers worldwide have expanded access to care.Yet pharmaceutical innovation hasn't kept pace. Since the blockbuster success of drugs such as Prozac and Zoloft in the 1990s and early 2000s, many of the industry's largest companies have scaled back their investments in the field.This isn't for lack of patient demand. More than one in five Americans lives with a mental illness, and existing treatments often have significant side effects and limited effectiveness.Now, signs of a cautious revival are emerging. In late 2023, Bristol Myers Squibb acquired Karuna Therapeutics for $14 billion, betting on a promising new schizophrenia treatment. And in January, Johnson & Johnson agreed to acquire Intra-Cellular Therapies  for $15 billion, adding a pill ","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU1291159041.SGD","LU1674673691.USD","SG9999018857.SGD","LU1003077747.HKD","ITCI","ABBV","BK4568","SG9999015952.SGD","SG9999017495.SGD","LU1989772840.SGD","SGXZ99366536.SGD","SGXZ57979304.SGD","LU0234570918.USD","LU0912757837.SGD","IE0004445239.USD","LU0965509283.SGD","IE00BDGV0183.EUR","BK4504","LU1280957306.USD","LU2357305700.SGD","JNJ","LU0661504455.SGD","BK4585","LU0079474960.USD","IE00B3PB1722.GBP","BK4559","LU1023059063.AUD","LU2265009873.SGD","LU0345769128.USD","LU0823416689.USD","LU1868836757.USD","LU0306807586.USD","LU0094547139.USD","LU0211328371.USD","BMY","LU1069344957.HKD","SG9999014880.SGD","LU0868494617.USD","IE00B2B36J28.USD","LU1196500208.SGD","LU2063271972.USD","LU0861579265.USD","LU2505996509.AUD","NBIX","BK4139","LU2112291526.USD","SG9999014898.SGD","LU1718418525.SGD","LU0203202063.USD"],"gpt_icon":1},{"id":"2518748907","title":"Neurocrine Biosciences to Present at the Stifel 2025 Virtual CNS Forum","url":"https://stock-news.laohu8.com/highlight/detail?id=2518748907","media":"PR Newswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2518748907?lang=en_us&edition=fundamental","pubTime":"2025-03-12 04:01","pubTimestamp":1741723260,"startTime":"0","endTime":"0","summary":"SAN DIEGO, March 11, 2025 /PRNewswire/ -- Neurocrine Biosciences, Inc.  will participate at the Stifel 2025 Virtual CNS Forum at 1:30 p.m. Eastern Time on Tuesday, March 18, 2025. Chief Executive Officer Kyle Gano and Chief Medical Officer Eiry Roberts will present at the conference.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/neurocrine-biosciences-present-stifel-2025-200100246.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/neurocrine-biosciences-present-stifel-2025-200100246.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["SF","LU2324357040.USD","LU2065170008.USD","NBIX","BK4135","CNS","BK4179","BK4127","LU0109394709.USD","LU0823416689.USD","FET","LU2065171311.SGD","BK4139","LU2065171402.SGD","LU0320765992.SGD","LU0889565916.HKD","LU2065169927.USD"],"gpt_icon":0},{"id":"2518571184","title":"RBC Cuts Price Target on Neurocrine Biosciences to $139 From $148, Keeps Sector Perform Rating","url":"https://stock-news.laohu8.com/highlight/detail?id=2518571184","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2518571184?lang=en_us&edition=fundamental","pubTime":"2025-03-11 18:29","pubTimestamp":1741688970,"startTime":"0","endTime":"0","summary":"Neurocrine Biosciences (NBIX) has an average rating of overweight and mean price target of $165.08, according to analysts polled by FactSet.(MT Newswires covers equity, commodity and economic research","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate","earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["NBIX"],"gpt_icon":0},{"id":"2517345249","title":"BUZZ-Morgan Stanley initiates Crinetics with 'outperform' on catalyst rich 2025","url":"https://stock-news.laohu8.com/highlight/detail?id=2517345249","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2517345249?lang=en_us&edition=fundamental","pubTime":"2025-03-08 03:27","pubTimestamp":1741375620,"startTime":"0","endTime":"0","summary":"BUZZ-Morgan Stanley initiates Crinetics with 'outperform' on catalyst rich 2025  ** Brokerage Morgan Stanley starts coverage on drug developer Crinetics CRNX.O, which focuses on developing treatments ","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250307:nL3N3PQ1F4:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["CRNX","NBIX"],"gpt_icon":0},{"id":"2517456257","title":"Neurocrine Coverage Assumed by Morgan Stanley at Overweight","url":"https://stock-news.laohu8.com/highlight/detail?id=2517456257","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2517456257?lang=en_us&edition=fundamental","pubTime":"2025-03-08 01:49","pubTimestamp":1741369740,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/NBIX/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  March 07, 2025 12:49 ET (17:49 GMT)","market":"other","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["NBIX"],"gpt_icon":0},{"id":"2517648456","title":"Positive Growth Outlook for Neurocrine Biosciences Driven by Ingrezza and Crenessity Sales Projections","url":"https://stock-news.laohu8.com/highlight/detail?id=2517648456","media":"TIPRANKS","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2517648456?lang=en_us&edition=fundamental","pubTime":"2025-03-07 20:06","pubTimestamp":1741349197,"startTime":"0","endTime":"0","summary":"Sean Laaman, an analyst from Morgan Stanley, has initiated a new Buy rating on Neurocrine (NBIX). Sean Laaman has given his Buy rating due to a com...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/ratings/positive-growth-outlook-for-neurocrine-biosciences-driven-by-ingrezza-and-crenessity-sales-projections?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/ratings/positive-growth-outlook-for-neurocrine-biosciences-driven-by-ingrezza-and-crenessity-sales-projections?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["NBIX"],"gpt_icon":0},{"id":"2517919505","title":"Neurocrine Biosciences (NasdaqGS:NBIX) Begins Phase 1 Study Of New VMAT2 Inhibitor For Neurological Conditions","url":"https://stock-news.laohu8.com/highlight/detail?id=2517919505","media":"Simply Wall St.","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2517919505?lang=en_us&edition=fundamental","pubTime":"2025-03-07 01:20","pubTimestamp":1741281601,"startTime":"0","endTime":"0","summary":"Neurocrine Biosciences announced the initiation of a Phase 1 clinical study for the compound NBI-1140675, a new VMAT2 inhibitor. This development could influence investor sentiment, though the company's stock experienced a 3% decline over the last week. This price movement may be linked to broader market concerns, such as the 2% drop in the tech-heavy Nasdaq Composite, driven by tariff uncertainties and volatile trading in tech stocks. While Neurocrine's broader portfolio and recent clinical advancements hold potential, overall market pressures, including the U.S. tariff situation and the resulting economic uncertainties, could be affecting investor behavior. Contributing factors also include a general 2% market decline due to investor concerns over tariffs and expected tightening of economic conditions. Despite this period's challenges, Neurocrine continues to strengthen its pipeline and expand applications for existing treatments like valbenazine, demonstrating ongoing commitment to ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/neurocrine-biosciences-nasdaqgs-nbix-begins-172001704.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LU0823416689.USD","LU2065171402.SGD","BK4139","LU0109394709.USD","LU2065170008.USD","LU0889565916.HKD","LU2065169927.USD","LU2065171311.SGD","LU2324357040.USD","LU0320765992.SGD","NBIX"],"gpt_icon":0},{"id":"2517103989","title":"BRIEF-Neurocrine Biosciences Announces Initiation Of Phase 1 Clinical Study Evaluating NBI-1140675","url":"https://stock-news.laohu8.com/highlight/detail?id=2517103989","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2517103989?lang=en_us&edition=fundamental","pubTime":"2025-03-05 22:29","pubTimestamp":1741184943,"startTime":"0","endTime":"0","summary":"BRIEF-Neurocrine Biosciences Announces Initiation Of Phase 1 Clinical Study Evaluating NBI-1140675March 5 (Reuters) - Neurocrine Biosciences Inc NBIX.O:NEUROCRINE BIOSCIENCES ANNOUNCES INITIATION OF P","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250305:nFWN3PO0HN:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","LU0823416689.USD","LU2065171402.SGD","LU0320765992.SGD","LU2324357040.USD","LU0109394709.USD","NBIX","LU2065171311.SGD","LU2065170008.USD","LU2065169927.USD","LU0889565916.HKD"],"gpt_icon":0},{"id":"2517147319","title":"Neurocrine begins Phase 1 clinical study of NBI-1140675","url":"https://stock-news.laohu8.com/highlight/detail?id=2517147319","media":"TIPRANKS","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2517147319?lang=en_us&edition=fundamental","pubTime":"2025-03-05 21:36","pubTimestamp":1741181762,"startTime":"0","endTime":"0","summary":"Neurocrine (NBIX) Biosciences announced the initiation of a Phase 1 clinical study to evaluate the safety, tolerability, pharmacokinetics and pharm...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/neurocrine-begins-phase-1-clinical-study-of-nbi-1140675?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/neurocrine-begins-phase-1-clinical-study-of-nbi-1140675?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["LU0889565916.HKD","LU0320765992.SGD","LU2065171311.SGD","NBIX","LU2324357040.USD","LU2065170008.USD","LU0823416689.USD","LU2065169927.USD","LU2065171402.SGD","LU0109394709.USD","BK4139","NBI"],"gpt_icon":0},{"id":"2517491450","title":"Neurocrine Biosciences Announces Initiation of Phase 1 Clinical Study Evaluating Nbi-1140675, a Second-Generation Vmat2 Inhibitor, in Healthy Adults","url":"https://stock-news.laohu8.com/highlight/detail?id=2517491450","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2517491450?lang=en_us&edition=fundamental","pubTime":"2025-03-05 21:30","pubTimestamp":1741181413,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250305:nFWN3PO0HN:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["LU0320765992.SGD","LU2065171311.SGD","NBIX","LU0889565916.HKD","BK4139","LU2065169927.USD","LU0109394709.USD","LU2065171402.SGD","LU2065170008.USD","LU2324357040.USD","LU0823416689.USD"],"gpt_icon":0},{"id":"2517173509","title":"Neurocrine Biosciences Announces Initiation of Phase 1 Clinical Study Evaluating NBI-1140675, a Second-Generation VMAT2 Inhibitor, in Healthy Adults","url":"https://stock-news.laohu8.com/highlight/detail?id=2517173509","media":"PR Newswire","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2517173509?lang=en_us&edition=fundamental","pubTime":"2025-03-05 21:30","pubTimestamp":1741181400,"startTime":"0","endTime":"0","summary":"SAN DIEGO, March 5, 2025 /PRNewswire/ -- Neurocrine Biosciences, Inc.  today announced the initiation of a Phase 1 clinical study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of investigational compound NBI-1140675 in healthy adult participants. NBI-1140675 is an investigational, oral, selective second-generation small molecule inhibitor of the vesicular monoamine transporter 2  in development for the potential treatment of certain neurological and neuropsychiatric conditions.NBI-1140675 joins NBI-1065890 as a second-generation VMAT2 inhibitor undergoing evaluation byNeurocrine in Phase 1 clinical studies. VMAT2 inhibitors have been clinically validated as effective treatments for hyperkinetic movement disorders, playing an important role in presynaptic dopamine storage and release. 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