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Bicycle Therapeutics Limited

8.60

-0.0700-0.81%

Post-market: 9.030.4300+5.00%16:20 EDT

Volume:318.44K

Turnover:2.72M

Market Cap:595.14M

PE:-2.96

High:8.92

Open:8.63

Low:8.26

Close:8.67

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Overview Company News Filings

Analysts’ Opinions Are Mixed on These Healthcare Stocks: Zoetis (ZTS), Walgreens Boots Alliance (WBA) and Bicycle Therapeutics (BCYC)

European Equities Traded in the US as American Depositary Receipts Kick Off Week Higher in Monday Trading

MT Newswires Live

B. Riley Adjusts Price Target on Bicycle Therapeutics to $17 From $28, Keeps Neutral Rating

MT Newswires Live

Bicycle Therapeutics Is Maintained at Buy by HC Wainwright & Co.

Bicycle Therapeutics Plc : H.c. Wainwright Cuts Target Price to $33 From $55

THOMSON REUTERS

Analysts Have Conflicting Sentiments on These Healthcare Companies: Ultragenyx Pharmaceutical (RARE), Bicycle Therapeutics (BCYC) and Quest Diagnostics (DGX)

Bicycle Therapeutics Plc : H.c. Wainwright Cuts Target Price to $33 From $55

THOMSON REUTERS

Sector Update: Health Care Stocks Edge Higher Late Afternoon

MT Newswires Live

Bicycle Therapeutics Reports Updates Across Zelenectide Pevedotin Program; Shares Slump

MT Newswires Live

Bicycle Therapeutics' Latest Trial Results Raise Questions -- Market Talk

Bicycle Therapeutics Is Maintained at Neutral by B. Riley Securities

European Equities Traded in the US as American Depositary Receipts Lower in Friday Trading, Down 1.5% for Week

MT Newswires Live

Bicycle Therapeutics Lead Cancer Drug Combined With Merck's Blockbuster Drug Shows 60% Overall Response Rate In Urothelial Cancer Patients

Bicycle Therapeutics Announces Data Updates Across Zelenectide Pevedotin Program and Development Strategy Leveraging Nectin4 Gene Amplification

THOMSON REUTERS

Bicycle Therapeutics Plc: Dose Selection and Topline Data From Phase 2/3 Duravelo-2 Trial Planned for 2H 2025

THOMSON REUTERS

Bicycle Therapeutics Announces Data Updates Across Zelenectide Pevedotin Program and Development Strategy Leveraging NECTIN4 Gene Amplification

European Equities Traded in the US as American Depositary Lower in Tuesday Trading

MT Newswires Live

Bicycle Therapeutics Expands Clinical Advisory Board with Three Distinguished Global Oncology Experts

European Equities Traded in the US as American Depositary Tread Water in Friday Trading

MT Newswires Live

Bicycle Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

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Opinions Are Mixed on These Healthcare Stocks: Zoetis (ZTS), Walgreens Boots Alliance (WBA) and Bicycle Therapeutics (BCYC)","url":"https://stock-news.laohu8.com/highlight/detail?id=2492977924","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2492977924?lang=en_us&edition=fundamental","pubTime":"2024-12-18 13:30","pubTimestamp":1734499816,"startTime":"0","endTime":"0","summary":"Companies in the Healthcare sector have received a lot of coverage today as analysts weigh in on Zoetis (ZTS – Research Report), Walgreens Boots Al...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/analysts-opinions-are-mixed-on-these-healthcare-stocks-zoetis-zts-walgreens-boots-alliance-wba-and-bicycle-therapeutics-bcyc?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/analysts-opinions-are-mixed-on-these-healthcare-stocks-zoetis-zts-walgreens-boots-alliance-wba-and-bicycle-therapeutics-bcyc?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["LU1941712348.USD","LU2271345857.HKD","BK4137","BCYC","LU0158827948.USD","BK4585","IE00B19Z9505.USD","LU0471298777.SGD","LU2308191902.HKD","LU2089283258.USD","LU0321505868.SGD","LU2023251221.USD","LU0345774631.USD","LU1941712264.USD","LU2089284900.SGD","LU0058720904.USD","BK4007","HCSG","LU0471298694.HKD","LU0289739699.SGD","LU0079474960.USD","ZTS","BK4128","LU0158827781.USD","WBA","BK4588","BK4139","LU0321505439.SGD","BK4534","LU0385154629.USD","LU2028103732.USD","LU2360106947.USD","LU2111349929.HKD","LU0345774391.USD"],"gpt_icon":0},{"id":"2492994616","title":"European Equities Traded in the US as American Depositary Receipts Kick Off Week Higher in Monday Trading","url":"https://stock-news.laohu8.com/highlight/detail?id=2492994616","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2492994616?lang=en_us&edition=fundamental","pubTime":"2024-12-17 00:10","pubTimestamp":1734365429,"startTime":"0","endTime":"0","summary":"European equities traded in the US as American depositary receipts started the week off higher late Monday morning, rising 0.32% to 1,343.34 on the S&P Europe Select ADR Index.From continental Europe, the gainers were led by biopharmaceutical companies argenx  and Grifols , which rose 4.3% and 3.9% respectively. They were followed by medical device maker EDAP TMS  and pharmaceutical company Ascendis Pharma , which increased 3.1% and 2.7% respectively.The decliners from continental Europe were led by biotech firm Evaxion Biotech  and biopharmaceutical company DBV Technologies , which fell 18% and 3.1% respectively. They were followed by biopharmaceutical company Cellectis  and petroleum refiner Equinor , which were down 2.8% and 2.4% respectively.From the UK and Ireland, the gainers were led by biopharmaceutical company Bicycle Therapeutics  and biotech firm Autolus Therapeutics , which advanced 8.6% and 5% respectively. They were followed by biopharmaceutical companies Verona Pharma  a","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK4162","EQNR","LU0320765646.SGD","BCYC","MREO","LU1162221912.USD","EVAX","BK4107","BK4139","ASND","BP","BK4007","LU0072461881.USD","GRFS","BK4588","BK4082","AMRN","LU0320765992.SGD","AFG","BK4585","DBVT","BK4505","LU0109394709.USD","TRIB","BK4117","LU0162691827.USD","ARGX","PUK","VRNA","BK4201","LU1829250122.USD","AUTL","EDAP","LU0889565916.HKD","CLLS"],"gpt_icon":0},{"id":"2491695412","title":"B. Riley Adjusts Price Target on Bicycle Therapeutics to $17 From $28, Keeps Neutral Rating","url":"https://stock-news.laohu8.com/highlight/detail?id=2491695412","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491695412?lang=en_us&edition=fundamental","pubTime":"2024-12-16 21:21","pubTimestamp":1734355263,"startTime":"0","endTime":"0","summary":"Bicycle Therapeutics (BCYC) has an average rating of buy and mean price target of $34.31, according to analysts polled by FactSet.(MT Newswires covers equity, commodity and economic research from majo","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate","earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BCYC","LENZ","RILY"],"gpt_icon":0},{"id":"2491671036","title":"Bicycle Therapeutics Is Maintained at Buy by HC Wainwright & Co.","url":"https://stock-news.laohu8.com/highlight/detail?id=2491671036","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491671036?lang=en_us&edition=fundamental","pubTime":"2024-12-16 20:14","pubTimestamp":1734351240,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/BCYC/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  December 16, 2024 07:14 ET (12:14 GMT)","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BCYC","LENZ"],"gpt_icon":0},{"id":"2491664811","title":"Bicycle Therapeutics Plc : H.c. Wainwright Cuts Target Price to $33 From $55","url":"https://stock-news.laohu8.com/highlight/detail?id=2491664811","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491664811?lang=en_us&edition=fundamental","pubTime":"2024-12-16 19:42","pubTimestamp":1734349360,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241216:nFWN3NH0J3:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BCYC","BK4139"],"gpt_icon":0},{"id":"2491661465","title":"Analysts Have Conflicting Sentiments on These Healthcare Companies: Ultragenyx Pharmaceutical (RARE), Bicycle Therapeutics (BCYC) and Quest Diagnostics (DGX)","url":"https://stock-news.laohu8.com/highlight/detail?id=2491661465","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491661465?lang=en_us&edition=fundamental","pubTime":"2024-12-16 19:30","pubTimestamp":1734348609,"startTime":"0","endTime":"0","summary":"Analysts have been eager to weigh in on the Healthcare sector with new ratings on Ultragenyx Pharmaceutical (RARE – Research Report), Bicycle Thera...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/analysts-have-conflicting-sentiments-on-these-healthcare-companies-ultragenyx-pharmaceutical-rare-bicycle-therapeutics-bcyc-and-quest-diagnostics-dgx?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/analysts-have-conflicting-sentiments-on-these-healthcare-companies-ultragenyx-pharmaceutical-rare-bicycle-therapeutics-bcyc-and-quest-diagnostics-dgx?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4567","BK4139","BK4583","BK4585","HCSG","BK4196","BK4588","BCYC","RARE","BK4137","DGX","LU1854103824.USD","LU1854104046.USD"],"gpt_icon":0},{"id":"2491796669","title":"Bicycle Therapeutics Plc : H.c. Wainwright Cuts Target Price to $33 From $55","url":"https://stock-news.laohu8.com/highlight/detail?id=2491796669","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491796669?lang=en_us&edition=fundamental","pubTime":"2024-12-16 19:19","pubTimestamp":1734347983,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241216:nAZN2UG6OP:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","BCYC"],"gpt_icon":0},{"id":"2491458806","title":"Sector Update: Health Care Stocks Edge Higher Late Afternoon","url":"https://stock-news.laohu8.com/highlight/detail?id=2491458806","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491458806?lang=en_us&edition=fundamental","pubTime":"2024-12-14 04:59","pubTimestamp":1734123576,"startTime":"0","endTime":"0","summary":"Health care stocks were edging up late Friday afternoon, with the NYSE Health Care Index and the Health Care Select Sector SPDR Fund  each adding 0.1%.The iShares Biotechnology ETF  shed 0.9%.In corporate news, Bicycle Therapeutics  shares plunged past 31% after it said topline data from a phase 1/2 trial of zelenectide pevedotin plus Merck's  pembrolizumab showed a 60% overall response rate in first-line metastatic urothelial cancer, in-line with existing therapies.Candel Therapeutics  shares sank 30.6% in recent trading, a day after it priced a public offering of 10 million shares at $6 apiece and pre-funded warrants for about 3.3 million shares at $5.99 per warrant to raise about $80 million in gross proceeds.Walgreens Boots Alliance's  potential buyer Sycamore Partners contacted banks including Bank of America , JPMorgan  and Wells Fargo  to finance a deal of over $10 billion, Sky News reported. Walgreens shares popped 6.8%.Centene  stock is undervalued, now that the company has la","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["LU0122379950.USD","IE00B775SV38.USD","BCYC","LU1988902786.USD","LU0203345920.USD","LU0965509283.SGD","XLV","SG9999001176.USD","SG9999015358.SGD","IE0002270589.USD","LU2129689431.USD","LU1061106388.HKD","LU0640476718.USD","IBB","LU0265550359.USD","LU0742534661.SGD","LU2237443382.USD","LU2242649171.HKD","WBA","LU0211328371.USD","LU1934455194.USD","LU0234572021.USD","LU0321505868.SGD","BAC","LU1280957306.USD","LU1720051017.SGD","LU0980610538.SGD","LU2357305700.SGD","LU1917777945.USD","MRK","CADL","LU2237443549.SGD","SG9999014575.USD","LU0265550946.USD","LU2552382058.USD","LU0417517546.SGD","LU1084165304.USD","LU0267386448.USD","LU0648000940.SGD","SG9999001176.SGD","LU1267930227.SGD","LU1244550221.USD","LU2237443978.SGD","LU1496350171.SGD","CNC","LU0477156797.USD","LU0208291251.USD","LU1894683348.USD","LU0211326839.USD","WBA.AU"],"gpt_icon":1},{"id":"2491301013","title":"Bicycle Therapeutics Reports Updates Across Zelenectide Pevedotin Program; Shares Slump","url":"https://stock-news.laohu8.com/highlight/detail?id=2491301013","media":"MT Newswires Live","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491301013?lang=en_us&edition=fundamental","pubTime":"2024-12-14 02:53","pubTimestamp":1734115981,"startTime":"0","endTime":"0","summary":"Bicycle Therapeutics  shares fell more than 31% in recent Friday trading after the company said topline data from a phase 1/2 trial of zelenectide pevedotin combined with Merck's  pembrolizumab showed a 60% overall response rate in first-line metastatic urothelial cancer, in-line with existing therapies.The company said it plans to report dose selection and topline data from a phase 2/3 trial in H2 2025.Bicycle also said treatment with zelenectide pevedotin alone in breast cancer patients with Nectin4 gene amplification showed \"enhanced anti-tumor activity.\"The company said it will advance its development strategy, including phase 1/2 trials in breast, lung, and multi-tumor cancers, starting in 2025.Price: 13.77, Change: -6.35, Percent Change: -31.55","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["LU0006306889.USD","LU1061106388.HKD","LU1934455863.HKD","LU2089984988.USD","SGXZ57979304.SGD","LU1934455277.USD","IE00BLSP4452.SGD","LU0320765489.SGD","LU0266013472.USD","BK4516","SG9999001440.SGD","LENZ","IE00BJT1NW94.SGD","LU2112291526.USD","LU1066051225.USD","LU0058720904.USD","IE0009355771.USD","LU0985320562.USD","LU2361045086.USD","BK4007","LU1917777945.USD","LU1093756168.USD","LU0203347892.USD","LU1989772923.USD","LU1989771016.USD","SG9999015341.SGD","LU0965509101.SGD","LU1941712348.USD","LU1941712264.USD","SG9999014575.USD","BK4585","LU0965509010.AUD","LU1934455194.USD","MRK","LU2324357040.USD","BK4533","LU0861579265.USD","IE00BFTCPJ56.SGD","LU1023059063.AUD","LU0070302665.USD","BCYC","IE00BBT3K403.USD","LU1974910355.USD","SG9999014542.SGD","LU1585245621.USD","LU1066051811.HKD","IE00B4R5TH58.HKD","SG9999015358.SGD","LU1983299246.USD","LU0203345920.USD"],"gpt_icon":0},{"id":"2491309899","title":"Bicycle Therapeutics' Latest Trial Results Raise Questions -- Market Talk","url":"https://stock-news.laohu8.com/highlight/detail?id=2491309899","media":"Dow Jones","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491309899?lang=en_us&edition=fundamental","pubTime":"2024-12-14 02:19","pubTimestamp":1734113940,"startTime":"0","endTime":"0","summary":"1319 ET - Bicycle Therapeutics takes a beating after sharing its latest cancer treatment trial results. B. Riley analyst Kalpit Patel says the results for Bicycle's zelenectide pevedotin therapy in conjunction with Merck's pembrolizumab to treat bladder cancer included \"a significant proportion of unconfirmed responses,\" and while the data are early, he says the effectiveness appears to be \"somewhat underwhelming,\" when compared to the established combination of Astellas' Padcev + pembro. Patel also says results for Bicycle's breast and lung cancer treatment relied on a post-hoc analysis, which carries \"an inherent risk of data mining.\" The analyst cautions that outcomes from such analyses often fail to replicate in later studies. Bicycle Therapeutics plunges 30% to $14.07.  ","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LENZ","BK4139","BCYC"],"gpt_icon":0},{"id":"2491052893","title":"Bicycle Therapeutics Is Maintained at Neutral by B. Riley Securities","url":"https://stock-news.laohu8.com/highlight/detail?id=2491052893","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491052893?lang=en_us&edition=fundamental","pubTime":"2024-12-14 01:48","pubTimestamp":1734112080,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/BCYC/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  December 13, 2024 12:48 ET (17:48 GMT)","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["RILY","BCYC","LENZ"],"gpt_icon":0},{"id":"2491918372","title":"European Equities Traded in the US as American Depositary Receipts Lower in Friday Trading, Down 1.5% for Week","url":"https://stock-news.laohu8.com/highlight/detail?id=2491918372","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491918372?lang=en_us&edition=fundamental","pubTime":"2024-12-14 00:10","pubTimestamp":1734106214,"startTime":"0","endTime":"0","summary":"European equities traded in the US as American depositary receipts were lower late Friday morning, declining 0.25% to 1,337.43 on the S&P Europe Select ADR Index, which is down 1.5% for the week.From ","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK7505","BK4020","BCYC","MTLS","BK4554","BK4585","BK4521","EVAX","AFG","ADAP","BK4117","BBVA","BK4207","DEO","BK4515","BDRX","AKTX","BK4107","BK4095","ING.AU","NCNA","BK7141","BK4007","VRNA","SAN.AU","DBVT","BK4591","BK7142","BK4023","SAN","TCBP","ING","BK4588","BK4546","ERIC","BK4139","DGE.UK","BK4169","NTZ"],"gpt_icon":1},{"id":"2491637878","title":"Bicycle Therapeutics Lead Cancer Drug Combined With Merck's Blockbuster Drug Shows 60% Overall Response Rate In Urothelial Cancer Patients","url":"https://stock-news.laohu8.com/highlight/detail?id=2491637878","media":"Benzinga","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491637878?lang=en_us&edition=fundamental","pubTime":"2024-12-13 20:50","pubTimestamp":1734094204,"startTime":"0","endTime":"0","summary":"On Thursday, Bicycle Therapeutics plc  announced that it presented data showing the enhanced anti-tumor activity of zelenectide pevedotin monotherapy in breast cancer patients withNECTIN4 gene amplification at the 2024 San Antonio Breast Conference Symposium.The company revealed topline combination data for zelenectide pevedotin plus Merck & Co Inc’s  Keytruda  in previously untreated  cisplatin-ineligible patients with metastatic urothelial cancer .Topline results from the ongoing Phase 1/2 Duravelo-1 trial evaluating zelenectide pevedotin weekly plus pembrolizumab once every three weeks showed:. 60% overall response rate   among efficacy-evaluable patients. Of the responses, five were confirmed, and seven were unconfirmed at the time of the data cut. Fifteen patients remained on treatment at the time of the data cut.The safety and tolerability profile was broadly consistent with late-line Duravelo-1 monotherapy and combination cohorts.Adverse events of clinical interest, such as peri","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/0jLzJaWMn9wZCoiKubfFfA--~B/aD01NTM7dz05ODM7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/Benzinga/817747ab3c609c2959b69e0e165b6c02","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/0jLzJaWMn9wZCoiKubfFfA--~B/aD01NTM7dz05ODM7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/Benzinga/817747ab3c609c2959b69e0e165b6c02"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/bicycle-therapeutics-lead-cancer-drug-125004885.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LU1941712264.USD","LU2361044865.SGD","SG9999001176.SGD","SG9999014542.SGD","BK4139","IE000M9KFDE8.USD","LU0070302665.USD","LU2324357040.USD","LU1974910355.USD","IE0002141913.USD","IE00BSNM7G36.USD","LU1057294990.SGD","LU0861579265.USD","LU1066051498.USD","LU1066053197.SGD","LU1066051225.USD","LU0965508806.USD","LU1093756168.USD","LU2023250843.SGD","IE00BBT3K403.USD","IE00BJJMRZ35.SGD","LU1093756325.SGD","LU0234572021.USD","LU0006306889.USD","LU1917777945.USD","LU1941712348.USD","SG9999002232.USD","LU0211331839.USD","BK4533","LU1116320901.HKD","LU0289739699.SGD","IE00BLSP4239.USD","LU2461242641.AUD","SG9999001440.SGD","SG9999001176.USD","IE0009355771.USD","MRK","BCYC","LU0985320562.USD","LU2468319806.SGD","SGXZ57979304.SGD","LU0265550946.USD","LENZ","LU1023059063.AUD","LU0320765489.SGD","LU0208291251.USD","LU0203345920.USD","LU2112291526.USD","LU1061106388.HKD","BK4559"],"gpt_icon":0},{"id":"2491636620","title":"Bicycle Therapeutics Announces Data Updates Across Zelenectide Pevedotin Program and Development Strategy Leveraging Nectin4 Gene Amplification","url":"https://stock-news.laohu8.com/highlight/detail?id=2491636620","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491636620?lang=en_us&edition=fundamental","pubTime":"2024-12-13 07:30","pubTimestamp":1734046237,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241212:nFWN3ND1NA:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BCYC","BK4139"],"gpt_icon":0},{"id":"2491366738","title":"Bicycle Therapeutics Plc: Dose Selection and Topline Data From Phase 2/3 Duravelo-2 Trial Planned for 2H 2025","url":"https://stock-news.laohu8.com/highlight/detail?id=2491366738","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491366738?lang=en_us&edition=fundamental","pubTime":"2024-12-13 07:30","pubTimestamp":1734046237,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241212:nFWN3ND1NA:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","BCYC"],"gpt_icon":0},{"id":"2491540369","title":"Bicycle Therapeutics Announces Data Updates Across Zelenectide Pevedotin Program and Development Strategy Leveraging NECTIN4 Gene Amplification","url":"https://stock-news.laohu8.com/highlight/detail?id=2491540369","media":"Business Wire","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491540369?lang=en_us&edition=fundamental","pubTime":"2024-12-13 07:30","pubTimestamp":1734046200,"startTime":"0","endTime":"0","summary":"Topline combination data for zelenectide pevedotin plus pembrolizumab in first-line metastatic urothelial cancer demonstrated a 60% overall response rate, in line with existing therapies. Dose selection and topline data from Phase 2/3 Duravelo-2 trial planned for 2H 2025. Heavily pretreated breast cancer and non-small cell lung cancer patients with NECTIN4 gene amplification and/or polysomy demonstrated an enhanced response to zelenectide pevedotin. \"The totality of the data shared today builds on the breadth of previously reported data for zelenectide pevedotin that we believe, when combined with our ambitious development strategy leveraging NECTIN4 gene amplification, position Bicycle as a leader in addressing Nectin-4 associated cancers,\" said Bicycle Therapeutics CEO Kevin Lee, Ph.D. \"We are encouraged by the topline zelenectide pevedotin data in combination with pembrolizumab in first-line mUC patients, which demonstrate zelenectide pevedotin’s response data are in line with other","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/tbb9IYToTIQRlm0bJbm5AA--~B/aD01MTI7dz0xMDI0O2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/business-wire.com/187bc2c42068fd97238ea444388916a2","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/tbb9IYToTIQRlm0bJbm5AA--~B/aD01MTI7dz0xMDI0O2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/business-wire.com/187bc2c42068fd97238ea444388916a2"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/bicycle-therapeutics-announces-data-updates-233000991.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LENZ","BCYC","BK4139"],"gpt_icon":0},{"id":"2490010141","title":"European Equities Traded in the US as American Depositary Lower in Tuesday Trading","url":"https://stock-news.laohu8.com/highlight/detail?id=2490010141","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2490010141?lang=en_us&edition=fundamental","pubTime":"2024-12-11 00:07","pubTimestamp":1733846871,"startTime":"0","endTime":"0","summary":"European equities traded in the US as American depositary receipts were lower late Tuesday morning, declining 0.38% to 1,348.76 on the S&P Europe Select ADR Index.From continental Europe, the gainers ","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK4134","LU0164880469.USD","LU0417516738.SGD","BK1231","BK4585","BCYC","BK4077","03143","HSBC","HSHD.SI","CLLS","BK4023","BP","SAN","00005","LU0823431647.USD","SAN.AU","DAVA","TRIB","EDAP","TRVG","HSBA.UK","DAVA.AU","CUK","AFG","BK4139","BK7142","LU1162221912.USD","LU0648005311.SGD","BK4132","OPRA","LU0320765646.SGD","BK4007","LU0149721374.USD","BK4082","BK4207","LU0348735423.USD","BK4107","AKTX","LU0072461881.USD","VEON","LU1829250122.USD","BK4117","BK4521","DBVT","BK4142","LU0162691827.USD","SLN","EVAX","LU2236285917.USD"],"gpt_icon":0},{"id":"2490092650","title":"Bicycle Therapeutics Expands Clinical Advisory Board with Three Distinguished Global Oncology Experts","url":"https://stock-news.laohu8.com/highlight/detail?id=2490092650","media":"Business Wire","labels":["executive"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2490092650?lang=en_us&edition=fundamental","pubTime":"2024-12-10 20:00","pubTimestamp":1733832000,"startTime":"0","endTime":"0","summary":"CAMBRIDGE, England & BOSTON, December 10, 2024----Bicycle Therapeutics plc , a pharmaceutical company pioneering a new and differentiated class of therapeutics based on its proprietary bicyclic peptide  technology, today announced the appointment of three new distinguished global oncology experts to its Clinical Advisory Board  to support the advancement of the company’s clinical oncology programs.\"We are delighted to welcome Skip, Markus and Niklas to our Clinical Advisory Board. Each of them has dedicated their careers to advancing the care of patients with cancer through the development of novel therapeutics,\" said Bicycle Therapeutics CEO Kevin Lee, Ph.D. \"Their expertise will provide invaluable guidance and insights for the global development of our clinical oncology programs as we work to develop our precision-targeted therapies for the benefit of patients around the world.\". Niklas Klümper, M.D., is a senior consultant for Urology & Genitourinary  Oncology at the University Hosp","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/rhKt97mgD5tlNKFYljX6pg--~B/aD01MTI7dz0xMDI0O2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/business-wire.com/3ab6813e53dc315d215afcf27ebe9de4","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/rhKt97mgD5tlNKFYljX6pg--~B/aD01MTI7dz0xMDI0O2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/business-wire.com/3ab6813e53dc315d215afcf27ebe9de4"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/bicycle-therapeutics-expands-clinical-advisory-120000029.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"executive","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BCYC","LENZ","BK4139","CAB"],"gpt_icon":0},{"id":"2489525285","title":"European Equities Traded in the US as American Depositary Tread Water in Friday Trading","url":"https://stock-news.laohu8.com/highlight/detail?id=2489525285","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2489525285?lang=en_us&edition=fundamental","pubTime":"2024-12-07 00:03","pubTimestamp":1733500993,"startTime":"0","endTime":"0","summary":"European equities traded in the US as American depositary receipts were treading water late Friday morning, edging 0.055% higher to 1,351.69 on the S&P Europe Select ADR Index, which has gained 1.4% f","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK4551","NVO","BK4134","MTLS","EQNR","BK4599","BK4535","LU1093756168.USD","BK4568","BK4107","AFG","LU1162221912.USD","BK4532","BK4505","BK4023","BK4585","BP","DAVA","IE00BZ1G4Q59.USD","SHEL","BNTX","BK4007","E","LU0154236417.USD","BK4141","LU0162691827.USD","BCYC","LU0648005311.SGD","TRIB","BK4082","LU0072461881.USD","BK4588","NVO.AU","BK7104","BK4546","LU0300736062.USD","LU0278409577.USD","BK4139","DAVA.AU","BK4201","LU1093756325.SGD","SQNS","LU0084288595.USD","OPRA","BK4548","SLN","IE00BKVL7J92.USD","DBVT","AMRN","MREO"],"gpt_icon":1},{"id":"2488541959","title":"Bicycle Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)","url":"https://stock-news.laohu8.com/highlight/detail?id=2488541959","media":"Business Wire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2488541959?lang=en_us&edition=fundamental","pubTime":"2024-12-03 05:05","pubTimestamp":1733173500,"startTime":"0","endTime":"0","summary":"CAMBRIDGE, England & BOSTON, December 02, 2024----Bicycle Therapeutics plc , today announced that on December 2, 2024, the Compensation Committee of the company’s Board of Directors granted to thirteen new employees inducement awards consisting of non-qualified share options to purchase an aggregate of 62,400 ordinary shares. These awards were made under Bicycle Therapeutics’ 2024 Inducement Plan and approved by the Compensation Committee as an inducement material to the employees entering into employment with the company in accordance with Nasdaq Listing Rule 5635.Each option has an exercise price equal to $20.40 per share, Bicycle Therapeutics’ closing trading price on November 29, 2024, and will vest over four years, with 25% of the underlying shares vesting on the one-year anniversary of the applicable vesting commencement date and the balance of the underlying shares vesting monthly thereafter over 36 months, subject to the employees’ continued service relationship with the 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