Allogene Therapeutics Unveils Promising Results for ALLO-316 in Kidney Cancer and Cema-Cel in Lymphoma at ASCO 2025

Reuters
23 May
Allogene <a href="https://laohu8.com/S/LENZ">Therapeutics</a> Unveils Promising Results for ALLO-316 in Kidney Cancer and Cema-Cel in Lymphoma at ASCO 2025

Allogene Therapeutics, Inc., a clinical-stage biotechnology company, has announced the publication of two significant abstracts ahead of the 2025 ASCO Annual Meeting. The first abstract highlights an oral presentation on ALLO-316, an investigational AlloCAR T product targeting CD70, which is being studied in patients with advanced or metastatic renal cell carcinoma. The presentation will discuss updated data from the Phase 1 TRAVERSE study, focusing on the Phase 1b expansion cohort where patients received a regimen of cyclophosphamide and fludarabine followed by a dose of 80 million CAR T cells. Additionally, the company will present a Trial-in-Progress poster on the Phase 2 ALPHA3 trial, which explores cemacabtagene ansegedleucel (cema-cel) as a first-line consolidation strategy for patients with large B-cell lymphoma who remain minimal residual disease positive after initial chemoimmunotherapy. These findings underscore Allogene's pioneering efforts in developing allogeneic CAR T products for cancer treatment.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Allogene Therapeutics Inc. published the original content used to generate this news brief via GlobeNewswire (Ref. ID: GNW9456941-en) on May 22, 2025, and is solely responsible for the information contained therein.

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