Regeneron Pharmaceuticals Reveals Trial Data of Drug Combination to Treat Multiple Myeloma

MT Newswires Live
23 May

Regeneron Pharmaceuticals (REGN) said late Thursday its initial phase 1b trials data of linvoseltamab in combination with carfilzomib or bortezomib to treat refractory multiple myeloma showed a 90% objective response rate after a 15-month follow-up.

Almost 76% of patients achieved a complete response, the company said.

Adverse events were recorded in over 50% of the patients, while grade 3 adverse events included neutropenia, cytokine release syndrome, diarrhea, and thrombocytopenia. Infections developed in 91% of patients, and serious adverse events occurred in 83%.

The company will present trial data at the American Society of Clinical Oncology 2025 Annual Meeting on June 2.

Shares were down 2% in after-hours trading.

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