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【君实生物：JS213 获得药物临床试验批准通知书】金融界2月5日消息，近日，君实生物收到国家药品监督管理局核准签发的《药物临床试验批准通知书》，AWT020 注射用无菌粉末（项目代号“JS213”）的临床试验申请获得批准。JS213 是 PD-1 和白细胞介素-2 双功能性抗体融合蛋白，主要用于晚期恶性肿瘤的治疗。截至披露日，国内外尚无同类靶点双功能性抗体融合蛋白产品获批上市。JS213 在海外已进入 I 期临床试验阶段。药品研发周期长、环节多且有不确定性因素，敬请投资者谨慎决策，注意防范投资风险。公司将积极推进项目并按规定披露后续进展。

招银国际：维持三生制药(01530)“买入”评级 PD-1/VEGF双抗早期临床数据公布

【奥赛康：子公司在2025年ASCO GI发布创新药ASKB589治疗一线晚期胃癌研究成果】奥赛康1月24日早间公告，子公司ASKGENELIMITED于2025年1月23日在美国临床肿瘤学会胃肠道肿瘤研讨会上以壁报形式公布在研生物创新药 ASKB589联合CAPOX及PD-1抑制剂在晚期胃/食管胃交界处腺癌一线治疗的最新临床研究成果。本项研究中，ASKB589联合CAPOX以及PD-1抑制剂作为一线治疗方案，表现出显著的肿瘤缓解，且显示出持续的生存获益、良好的耐受性，联合PD-1抑制剂给药并未观察到额外的安全性风险。本研究结果支持开展以CLDN18.2中高表达的IV期胃/胃食管交界处腺癌患者为目标人群的ASKB589三联疗法III期临床研究。

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