美股详情

本页面由Tiger Fintech (Singapore) Pte. Ltd.提供服务

Iterum Therapeutics Plc

0.9700

-0.0100-1.02%

盘后：0.98980.0198+2.04%19:44 EDT

成交量：40.30万

成交额：39.45万

市值：3,880.00万

市盈率：-1.04

高：0.9977

开：0.9837

低：0.9650

收：0.9800

数据加载中...

总览公司新闻公告

持股变动声明

Statement of changes in beneficial ownership of securities

持股变动声明

Statement of changes in beneficial ownership of securities

持股变动声明

Statement of changes in beneficial ownership of securities

持股变动声明

Statement of changes in beneficial ownership of securities

持股变动声明

Statement of changes in beneficial ownership of securities

重要事件披露

Current report, item 5.07

持股变动声明

Statement of changes in beneficial ownership of securities

重要事件披露

Current report, items 2.02 and 9.01

季度报告

Quarterly report [Sections 13 or 15(d)]

SEC问询函

SEC问询函

SEC问询函

SEC问询函

[修订]招股说明书

SEC问询函

{"basename":"/hans","ssrTDKData":{"titleTemplate":"%s - 老虎证券","title":"老虎证券全球投资理财平台| 一站式投资美股新股港股A股","description":"老虎证券助您一站式投资美股，新股，港股，A股等全球金融理财产品。新加坡华人最信赖的在线投资平台，现在加入即享低费用，24/5 无时差炒美股投资理财！","keywords":"老虎证券,老虎证券开户,老虎券商,老虎证券官网,老虎证券app,tigertrade老虎证券,股票,炒股,新加坡股票交易平台,投资,投资理财","social":{"ogDescription":"老虎证券助您一站式投资美股，新股，港股，A股等全球金融理财产品。新加坡华人最信赖的在线投资平台，现在加入即享低费用，24/5 无时差炒美股投资理财！","ogImage":"https://c1.itigergrowtha.com/portal5/static/media/og-logo.be62fbe1.png","ogUrl":"https://www-web.itiger.com/hans/stock/ITRM/filings?page=10"},"companyName":"老虎证券"},"pageData":{"isMobile":false,"isTiger":false,"isTTM":true,"region":"SGP","license":"TBSG","edition":"fundamental","symbol":"ITRM","isAnalysisPage":false},"__swrFallback__":{"@#url:\"https://hq.skytigris.cn/stock_info/detail/global\",params:#delay:false,,method:\"POST\",data:#items:@#symbol:\"ITRM\",,,,,undefined,":{"symbol":"ITRM","market":"US","secType":"STK","nameCN":"Iterum Therapeutics Plc","latestPrice":0.97,"timestamp":1752696000000,"preClose":0.98,"halted":0,"volume":403035,"hourTrading":{"tag":"盘后","latestPrice":0.9898,"preClose":0.97,"latestTime":"19:44 EDT","volume":16128,"amount":15769.0181,"timestamp":1752709483763},"delay":0,"floatShares":39254124,"shares":40000000,"eps":-0.928357,"marketStatus":"未开盘","change":-0.01,"latestTime":"07-16 16:00:00 EDT","open":0.9837,"high":0.9977,"low":0.965,"amount":394458.63686925,"amplitude":0.033367,"askPrice":0,"askSize":0,"bidPrice":0,"bidSize":0,"shortable":3,"etf":0,"ttmEps":-0.928357,"tradingStatus":0,"nextMarketStatus":{"tag":"盘前交易","tradingStatus":1,"beginTime":1752739200000},"marketStatusCode":0,"adr":0,"adrRate":0,"listingDate":1527220800000,"exchange":"NASDAQ","adjPreClose":0.98,"preHourTrading":{"tag":"盘前","latestPrice":1.0099,"preClose":0.98,"latestTime":"09:29 EDT","volume":7458,"amount":7285.72497312,"timestamp":1752672545349},"postHourTrading":{"tag":"盘后","latestPrice":0.9898,"preClose":0.97,"latestTime":"19:44 EDT","volume":16128,"amount":15769.0181,"timestamp":1752709483763},"volumeRatio":0.3814},"@#url:\"https://hq.skytigris.cn/stock_info/fundamental/all\",params:#delay:false,,method:\"POST\",data:#items:@#symbol:\"ITRM\",,,,,undefined,":{"symbol":"ITRM","floatShares":39254124,"roa":"-38.60%","roe":"-555.68%","lyrEps":-1.25761,"volumeRatio":0.3814,"shares":40000000,"dividePrice":0,"high":0.9977,"amplitude":0.033367,"preClose":0.98,"low":0.965,"week52Low":0.808,"pbRate":"-15.19","week52High":3.02,"institutionHeld":0,"latestPrice":0.97,"eps":-0.928357,"divideRate":0,"volume":403035,"delay":0,"ttmEps":-0.928357,"open":0.9837,"prevYearClose":1.77,"prevWeekClose":1.13,"prevMonthClose":0.995,"prevQuarterClose":0.995,"fiveDayClose":1.06,"twentyDayClose":1,"sixtyDayClose":1.08},"$inf$@#url:\"https://stock-news.skytigris.cn/v3/notice/important/events/list\",params:#symbol:\"ITRM\",pageSize:20,pageCount:10,market:\"us\",,,undefined,":[{"items":[{"cdn_pdf":false,"hasAttachments":true,"id":"8304945","market":"us","labels":[],"media":"sec.gov","original_id":"AN89924319017204-ITRM","pdf_url":null,"pub_time":1560700800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Statement of changes in beneficial ownership of securities","symbol":"ITRM","title":"Statement of changes in beneficial ownership of securities","titleType":"持股变动声明","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1659323/000089924319017204/0000899243-19-017204-index.htm","us_notice_code":"Form 4","us_title_en":"Statement of changes in beneficial ownership of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"FORM 4 SUBMISSION","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1247851/000089924319017204/xslF345X03/doc4.xml","primary":true,"translateUrl":null,"linkName":"doc4.html","type":"4","id":"NTFILE5kxyqDWVoxMRQL1b","market":"us","size":0},{"description":"FORM 4 SUBMISSION","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1247851/000089924319017204/doc4.xml","primary":false,"translateUrl":null,"linkName":"doc4.xml","type":"4","id":"NTFILE9ZjjgbvRTbrLw9jb","market":"us","size":4130}],"type_name":"交易披露","type_name_en":"Transaction Related","titleTypeEn":"Statement Of Changes In Beneficial Ownership","us_type":"usAnnouncement","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"持股变动声明","pubTime":"2019-06-17 00:00","pubTimestamp":1560700800,"title_zh":"Statement of changes in beneficial ownership of securities","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"8304944","market":"us","labels":[],"media":"sec.gov","original_id":"AN89924319017203-ITRM","pdf_url":null,"pub_time":1560700800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Statement of changes in beneficial ownership of securities","symbol":"ITRM","title":"Statement of changes in beneficial ownership of securities","titleType":"持股变动声明","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1659323/000089924319017203/0000899243-19-017203-index.htm","us_notice_code":"Form 4","us_title_en":"Statement of changes in beneficial ownership of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"FORM 4 SUBMISSION","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1380178/000089924319017203/xslF345X03/doc4.xml","primary":true,"translateUrl":null,"linkName":"doc4.html","type":"4","id":"NTFILE7ZLQtpuHz7UbQgxU","market":"us","size":0},{"description":"FORM 4 SUBMISSION","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1380178/000089924319017203/doc4.xml","primary":false,"translateUrl":null,"linkName":"doc4.xml","type":"4","id":"NTFILEFckd2NG8n96Gwur4","market":"us","size":4002}],"type_name":"交易披露","type_name_en":"Transaction Related","titleTypeEn":"Statement Of Changes In Beneficial Ownership","us_type":"usAnnouncement","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"持股变动声明","pubTime":"2019-06-17 00:00","pubTimestamp":1560700800,"title_zh":"Statement of changes in beneficial ownership of securities","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"8304943","market":"us","labels":[],"media":"sec.gov","original_id":"AN89924319017209-ITRM","pdf_url":null,"pub_time":1560700800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Statement of changes in beneficial ownership of securities","symbol":"ITRM","title":"Statement of changes in beneficial ownership of securities","titleType":"持股变动声明","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1659323/000089924319017209/0000899243-19-017209-index.htm","us_notice_code":"Form 4","us_title_en":"Statement of changes in beneficial ownership of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"FORM 4 SUBMISSION","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1624670/000089924319017209/xslF345X03/doc4.xml","primary":true,"translateUrl":null,"linkName":"doc4.html","type":"4","id":"NTFILEH3fuUuBNSmDkS9rR","market":"us","size":0},{"description":"FORM 4 SUBMISSION","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1624670/000089924319017209/doc4.xml","primary":false,"translateUrl":null,"linkName":"doc4.xml","type":"4","id":"NTFILE2af9RFC4pVFxSgjV","market":"us","size":4147}],"type_name":"交易披露","type_name_en":"Transaction Related","titleTypeEn":"Statement Of Changes In Beneficial Ownership","us_type":"usAnnouncement","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"持股变动声明","pubTime":"2019-06-17 00:00","pubTimestamp":1560700800,"title_zh":"Statement of changes in beneficial ownership of securities","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"8304942","market":"us","labels":[],"media":"sec.gov","original_id":"AN89924319017201-ITRM","pdf_url":null,"pub_time":1560700800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Statement of changes in beneficial ownership of securities","symbol":"ITRM","title":"Statement of changes in beneficial ownership of securities","titleType":"持股变动声明","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1659323/000089924319017201/0000899243-19-017201-index.htm","us_notice_code":"Form 4","us_title_en":"Statement of changes in beneficial ownership of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"FORM 4 SUBMISSION","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1365617/000089924319017201/xslF345X03/doc4.xml","primary":true,"translateUrl":null,"linkName":"doc4.html","type":"4","id":"NTFILE3y4BowvADJ9q8aRg","market":"us","size":0},{"description":"FORM 4 SUBMISSION","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1365617/000089924319017201/doc4.xml","primary":false,"translateUrl":null,"linkName":"doc4.xml","type":"4","id":"NTFILE55CJRnmfWUAUaNr2","market":"us","size":6565}],"type_name":"交易披露","type_name_en":"Transaction Related","titleTypeEn":"Statement Of Changes In Beneficial Ownership","us_type":"usAnnouncement","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"持股变动声明","pubTime":"2019-06-17 00:00","pubTimestamp":1560700800,"title_zh":"Statement of changes in beneficial ownership of securities","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"8304941","market":"us","labels":[],"media":"sec.gov","original_id":"AN89924319017199-ITRM","pdf_url":null,"pub_time":1560700800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Statement of changes in beneficial ownership of securities","symbol":"ITRM","title":"Statement of changes in beneficial ownership of securities","titleType":"持股变动声明","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1659323/000089924319017199/0000899243-19-017199-index.htm","us_notice_code":"Form 4","us_title_en":"Statement of changes in beneficial ownership of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"FORM 4 SUBMISSION","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1245624/000089924319017199/xslF345X03/doc4.xml","primary":true,"translateUrl":null,"linkName":"doc4.html","type":"4","id":"NTFILE8R3BHebjLkjxE9Rk","market":"us","size":0},{"description":"FORM 4 SUBMISSION","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1245624/000089924319017199/doc4.xml","primary":false,"translateUrl":null,"linkName":"doc4.xml","type":"4","id":"NTFILE8FgwMfgXHUJ6FFbb","market":"us","size":4132}],"type_name":"交易披露","type_name_en":"Transaction Related","titleTypeEn":"Statement Of Changes In Beneficial Ownership","us_type":"usAnnouncement","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"持股变动声明","pubTime":"2019-06-17 00:00","pubTimestamp":1560700800,"title_zh":"Statement of changes in beneficial ownership of securities","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"8304940","market":"us","labels":[],"media":"sec.gov","original_id":"AN156459019022668-ITRM","pdf_url":null,"pub_time":1560700800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Current report, item 5.07","symbol":"ITRM","title":"Current report, item 5.07","titleType":"重要事件披露","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1659323/000156459019022668/0001564590-19-022668-index.htm","us_notice_code":"Form 8-K","us_title_en":"Current report, item 5.07","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"8-K","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000156459019022668/itrm-8k_20190613.htm","primary":true,"translateUrl":null,"linkName":"itrm-8k_20190613.htm","type":"8-K","id":"NTFILE88tFhZhwJwWsdpA9","market":"us","size":39322}],"type_name":"交易披露","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"usAnnouncement","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"重要事件披露","pubTime":"2019-06-17 00:00","pubTimestamp":1560700800,"title_zh":"Current report, item 5.07","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"8304939","market":"us","labels":[],"media":"sec.gov","original_id":"AN89924319017206-ITRM","pdf_url":null,"pub_time":1560700800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Statement of changes in beneficial ownership of securities","symbol":"ITRM","title":"Statement of changes in beneficial ownership of securities","titleType":"持股变动声明","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1659323/000089924319017206/0000899243-19-017206-index.htm","us_notice_code":"Form 4","us_title_en":"Statement of changes in beneficial ownership of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"FORM 4 SUBMISSION","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1322927/000089924319017206/xslF345X03/doc4.xml","primary":true,"translateUrl":null,"linkName":"doc4.html","type":"4","id":"NTFILE2UxGvyELaRV4AR2C","market":"us","size":0},{"description":"FORM 4 SUBMISSION","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1322927/000089924319017206/doc4.xml","primary":false,"translateUrl":null,"linkName":"doc4.xml","type":"4","id":"NTFILEAYm9EaW4AqQp9evA","market":"us","size":4026}],"type_name":"交易披露","type_name_en":"Transaction Related","titleTypeEn":"Statement Of Changes In Beneficial Ownership","us_type":"usAnnouncement","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"持股变动声明","pubTime":"2019-06-17 00:00","pubTimestamp":1560700800,"title_zh":"Statement of changes in beneficial ownership of securities","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"8187798","market":"us","labels":[],"media":"sec.gov","original_id":"AN156459019018965-ITRM","pdf_url":null,"pub_time":1557763200000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Current report, items 2.02 and 9.01","symbol":"ITRM","title":"Current report, items 2.02 and 9.01","titleType":"重要事件披露","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1659323/000156459019018965/0001564590-19-018965-index.htm","us_notice_code":"Form 8-K","us_title_en":"Statement of changes in beneficial ownership of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"8-K","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000156459019018965/itrm-8k_20190514.htm","primary":true,"translateUrl":null,"linkName":"itrm-8k_20190514.htm","type":"8-K","id":"NTFILE5eixrHRQrvHXUhVY","market":"us","size":33252},{"description":"EX-99.1","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000156459019018965/itrm-ex991_6.htm","primary":false,"translateUrl":null,"linkName":"itrm-ex991_6.htm","type":"EX-99.1","id":"NTFILE9suNXFxQ82HxMq3U","market":"us","size":110388},{"description":"GRAPHIC","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000156459019018965/gaivcqri3cvr000001.jpg","primary":false,"translateUrl":null,"linkName":"gaivcqri3cvr000001.jpg","type":"GRAPHIC","id":"NTFILEAmMdAiXNsFFiy4m4","market":"us","size":6243}],"type_name":"交易披露","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"usAnnouncement","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"重要事件披露","pubTime":"2019-05-14 00:00","pubTimestamp":1557763200,"title_zh":"Current report, items 2.02 and 9.01","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"8187797","market":"us","labels":[],"media":"sec.gov","original_id":"AN156459019018968-ITRM","pdf_url":null,"pub_time":1557763200000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Quarterly report [Sections 13 or 15(d)]","symbol":"ITRM","title":"Quarterly report [Sections 13 or 15(d)]","titleType":"季度报告","type":"usFinancials","url":"https://www.sec.gov/Archives/edgar/data/1659323/000156459019018968/0001564590-19-018968-index.htm","us_notice_code":"Form 10-Q","us_title_en":"Statement of changes in beneficial ownership of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"10-Q","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000156459019018968/itrm-10q_20190331.htm","primary":true,"translateUrl":null,"linkName":"itrm-10q_20190331.htm","type":"10-Q","id":"NTFILEGPKELzMKrK9zwMFG","market":"us","size":1996437},{"description":"EX-31.1","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000156459019018968/itrm-ex311_7.htm","primary":false,"translateUrl":null,"linkName":"itrm-ex311_7.htm","type":"EX-31.1","id":"NTFILE2N7XUFQJ2HPk4Q3F","market":"us","size":17477},{"description":"EX-31.2","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000156459019018968/itrm-ex312_8.htm","primary":false,"translateUrl":null,"linkName":"itrm-ex312_8.htm","type":"EX-31.2","id":"NTFILEJ8rn42j1Si2sZ7V4","market":"us","size":17785},{"description":"EX-32.1","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000156459019018968/itrm-ex321_9.htm","primary":false,"translateUrl":null,"linkName":"itrm-ex321_9.htm","type":"EX-32.1","id":"NTFILE5XaEobUeiBMTFcG4","market":"us","size":10549},{"description":"EX-32.2","seq":5,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000156459019018968/itrm-ex322_6.htm","primary":false,"translateUrl":null,"linkName":"itrm-ex322_6.htm","type":"EX-32.2","id":"NTFILE3KLP1AMAe2f2o4XS","market":"us","size":10426}],"type_name":"财务报告","type_name_en":"Financial Report","titleTypeEn":"Quarterly Report","us_type":"usFinancials","us_type_zh":"财务报告","earn_infos":[],"event_type":"important_notice","event_name":"季度报告","pubTime":"2019-05-14 00:00","pubTimestamp":1557763200,"title_zh":"Quarterly report [Sections 13 or 15(d","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"4284719","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312518170379-ITRM","pdf_url":null,"pub_time":1526918400000,"showTitleType":true,"size":0,"source":"sec_us","summary":"","symbol":"ITRM","title":"","titleType":"SEC问询函","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518170379/0001193125-18-170379-index.htm","us_notice_code":"Form CORRESP","us_title_en":"[Cover]Correspondence","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518170379/filename1.htm","primary":true,"translateUrl":null,"linkName":"filename1.htm","type":"CORRESP","id":"NTFILE6gnZEwF8jEWGECsM","market":"us","size":8683}],"type_name":"交易披露","type_name_en":"Transaction Related","titleTypeEn":"Correspondence","us_type":"usAnnouncement","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"SEC问询函","pubTime":"2018-05-22 00:00","pubTimestamp":1526918400,"title_zh":"","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"4284707","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312518170385-ITRM","pdf_url":null,"pub_time":1526918400000,"showTitleType":true,"size":0,"source":"sec_us","summary":"","symbol":"ITRM","title":"","titleType":"SEC问询函","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518170385/0001193125-18-170385-index.htm","us_notice_code":"Form CORRESP","us_title_en":"[Cover]Correspondence","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518170385/filename1.htm","primary":true,"translateUrl":null,"linkName":"filename1.htm","type":"CORRESP","id":"NTFILED8bY5K7ugAX1x6pN","market":"us","size":11544}],"type_name":"交易披露","type_name_en":"Transaction Related","titleTypeEn":"Correspondence","us_type":"usAnnouncement","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"SEC问询函","pubTime":"2018-05-22 00:00","pubTimestamp":1526918400,"title_zh":"","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"4284735","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312518164732-ITRM","pdf_url":null,"pub_time":1526400000000,"showTitleType":true,"size":0,"source":"sec_us","summary":"","symbol":"ITRM","title":"","titleType":"SEC问询函","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518164732/0001193125-18-164732-index.htm","us_notice_code":"Form CORRESP","us_title_en":"[Amend] [Cover]General form for registration of securities under the Securities Act of 1933","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"AMENDMENT #2 TO FORM S-1","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518164732/d522368ds1a.htm","primary":true,"translateUrl":null,"linkName":"d522368ds1a.htm","type":"S-1/A","id":"NTFILEBWHJRutW3pNHGXqL","market":"us","size":2049759},{"description":"CONSTITUTION, AS CURRENTLY IN EFFECT.","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518164732/d522368dex31.htm","primary":false,"translateUrl":null,"linkName":"d522368dex31.htm","type":"EX-3.1","id":"NTFILEGjmetjFu7hRv9BT2","market":"us","size":300232},{"description":"FORM OF CONSTITUTION","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518164732/d522368dex32.htm","primary":false,"translateUrl":null,"linkName":"d522368dex32.htm","type":"EX-3.2","id":"NTFILEApoi7d7xWpkFGaRD","market":"us","size":442689},{"description":"OPINION OF A&L GOODBODY","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518164732/d522368dex51.htm","primary":false,"translateUrl":null,"linkName":"d522368dex51.htm","type":"EX-5.1","id":"NTFILEXUfv5uqm7YwgVCeQ","market":"us","size":26842},{"description":"2018 EQUITY INCENTIVE PLAN","seq":5,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518164732/d522368dex106.htm","primary":false,"translateUrl":null,"linkName":"d522368dex106.htm","type":"EX-10.6","id":"NTFILER5RZh1o5Lmtz3irv","market":"us","size":152801},{"description":"NON-EMPLOYEE DIRECTOR COMPENSATION POLICY","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518164732/d522368dex1018.htm","primary":false,"translateUrl":null,"linkName":"d522368dex1018.htm","type":"EX-10.18","id":"NTFILE3Z9Wh4E6byjDwibT","market":"us","size":16083},{"description":"CONSENT OF KPMG","seq":7,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518164732/d522368dex231.htm","primary":false,"translateUrl":null,"linkName":"d522368dex231.htm","type":"EX-23.1","id":"NTFILEkNstRXS7r78Lj39m","market":"us","size":2124},{"description":"GRAPHIC","seq":9,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518164732/g522368g0322073442413.jpg","primary":false,"translateUrl":null,"linkName":"g522368g0322073442413.jpg","type":"GRAPHIC","id":"NTFILEHT4gBJMw4q91kCpe","market":"us","size":2253},{"description":"GRAPHIC","seq":10,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518164732/g522368g12p78.jpg","primary":false,"translateUrl":null,"linkName":"g522368g12p78.jpg","type":"GRAPHIC","id":"NTFILEFZjCzGyX7drfXeWw","market":"us","size":3421},{"description":"GRAPHIC","seq":11,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518164732/g522368g19c10.jpg","primary":false,"translateUrl":null,"linkName":"g522368g19c10.jpg","type":"GRAPHIC","id":"NTFILEytzR4oqmozDjFb4o","market":"us","size":130605},{"description":"GRAPHIC","seq":12,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518164732/g522368g20i14.jpg","primary":false,"translateUrl":null,"linkName":"g522368g20i14.jpg","type":"GRAPHIC","id":"NTFILEDVQmLurVekurjmAW","market":"us","size":131580},{"description":"GRAPHIC","seq":13,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518164732/g522368g29x80.jpg","primary":false,"translateUrl":null,"linkName":"g522368g29x80.jpg","type":"GRAPHIC","id":"NTFILE7q92bvSeW2cbtqcL","market":"us","size":136035},{"description":"GRAPHIC","seq":14,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518164732/g522368g43z47.jpg","primary":false,"translateUrl":null,"linkName":"g522368g43z47.jpg","type":"GRAPHIC","id":"NTFILE7bgwrvEahegHCQER","market":"us","size":83256},{"description":"GRAPHIC","seq":15,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518164732/g522368g47p15.jpg","primary":false,"translateUrl":null,"linkName":"g522368g47p15.jpg","type":"GRAPHIC","id":"NTFILE5VYjxNeiDoWKYNjY","market":"us","size":159013},{"description":"GRAPHIC","seq":16,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518164732/g522368g73n73.jpg","primary":false,"translateUrl":null,"linkName":"g522368g73n73.jpg","type":"GRAPHIC","id":"NTFILE6xPxYYUZLCfASjzT","market":"us","size":47677},{"description":"","seq":17,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518164732/filename17.htm","primary":false,"translateUrl":null,"linkName":"filename17.htm","type":"CORRESP","id":"NTFILE8ygDkUyPur7YCNif","market":"us","size":18255}],"type_name":"交易披露","type_name_en":"Transaction Related","titleTypeEn":"Correspondence","us_type":"usAnnouncement","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"SEC问询函","pubTime":"2018-05-16 00:00","pubTimestamp":1526400000,"title_zh":"","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"4284728","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312518155571-ITRM","pdf_url":null,"pub_time":1525708800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"","symbol":"ITRM","title":"","titleType":"SEC问询函","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518155571/0001193125-18-155571-index.htm","us_notice_code":"Form CORRESP","us_title_en":"[Cover]Correspondence","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518155571/filename1.htm","primary":true,"translateUrl":null,"linkName":"filename1.htm","type":"CORRESP","id":"NTFILE74ev3wceWWTXFj7G","market":"us","size":43996},{"description":"GRAPHIC","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518155571/g522368g57e82.jpg","primary":false,"translateUrl":null,"linkName":"g522368g57e82.jpg","type":"GRAPHIC","id":"NTFILE5dH7xWBC6YZLxxGk","market":"us","size":9547}],"type_name":"交易披露","type_name_en":"Transaction Related","titleTypeEn":"Correspondence","us_type":"usAnnouncement","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"SEC问询函","pubTime":"2018-05-08 00:00","pubTimestamp":1525708800,"title_zh":"","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"4284730","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312518152964-ITRM","pdf_url":null,"pub_time":1525363200000,"showTitleType":true,"size":0,"source":"sec_us","summary":"","symbol":"ITRM","title":"","titleType":"[修订]招股说明书","type":"usProspectusesRegistrations","url":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518152964/0001193125-18-152964-index.htm","us_notice_code":"Form S-1/A","us_title_en":"[Amend] General form for registration of securities under the Securities Act of 1933","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"AMENDMENT #1 TO FORM S-1","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518152964/d522368ds1a.htm","primary":true,"translateUrl":null,"linkName":"d522368ds1a.htm","type":"S-1/A","id":"NTFILEDq8UhCusyviiwdxd","market":"us","size":2034214},{"description":"AMENDMENT TO EMPLOYMENT AGREEMENT - COREY N. FISHMAN","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518152964/d522368dex1013.htm","primary":false,"translateUrl":null,"linkName":"d522368dex1013.htm","type":"EX-10.13","id":"NTFILE6J8Vh3q47Qb4zfF8","market":"us","size":11266},{"description":"AMENDMENT TO EMPLOYMENT AGREEMENT - JUDITH M. MATTHEWS","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518152964/d522368dex1016.htm","primary":false,"translateUrl":null,"linkName":"d522368dex1016.htm","type":"EX-10.16","id":"NTFILE57D89TAGXXgoXH3y","market":"us","size":11223},{"description":"LOAN AND SECURITY AGREEMENT","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518152964/d522368dex1019.htm","primary":false,"translateUrl":null,"linkName":"d522368dex1019.htm","type":"EX-10.19","id":"NTFILE7xD8eYVkbLxkyzBY","market":"us","size":342318},{"description":"INTELLECTUAL PROPERTY SECURITY AGREEMENT","seq":5,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518152964/d522368dex1020.htm","primary":false,"translateUrl":null,"linkName":"d522368dex1020.htm","type":"EX-10.20","id":"NTFILECJTZi39JQ93frzTt","market":"us","size":31766},{"description":"WARRANT TO SUBSCRIBE FOR SHARES - SILICON VALLEY BANK","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518152964/d522368dex1021.htm","primary":false,"translateUrl":null,"linkName":"d522368dex1021.htm","type":"EX-10.21","id":"NTFILEB7CyUXkb56eYTjZ1","market":"us","size":82000},{"description":"WARRANT TO SUBSCRIBE FOR SHARES - LIFE SCIENCES FUND II LLC","seq":7,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518152964/d522368dex1022.htm","primary":false,"translateUrl":null,"linkName":"d522368dex1022.htm","type":"EX-10.22","id":"NTFILE4pLEpBDArkGdR1yw","market":"us","size":76930},{"description":"ADDITIONAL FORM OF WARRANT TO SUBSCRIBE FOR ORDINARY SHARES- SILICON VALLEY BANK","seq":8,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518152964/d522368dex1023.htm","primary":false,"translateUrl":null,"linkName":"d522368dex1023.htm","type":"EX-10.23","id":"NTFILEGc5BVw1vb1Wxnbse","market":"us","size":77517},{"description":"ADDITIONAL FORM OF WARRANT TO SUBSCRIBE FOR ORDINARY SHARES- LIFE SCIENCES FD II","seq":9,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518152964/d522368dex1024.htm","primary":false,"translateUrl":null,"linkName":"d522368dex1024.htm","type":"EX-10.24","id":"NTFILEETEo3JEeDrCFxjrC","market":"us","size":73594},{"description":"CONSENT OF KPMG","seq":10,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518152964/d522368dex231.htm","primary":false,"translateUrl":null,"linkName":"d522368dex231.htm","type":"EX-23.1","id":"NTFILEHvevP7gvSkZkJchR","market":"us","size":1966},{"description":"GRAPHIC","seq":11,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518152964/g522368g19c10.jpg","primary":false,"translateUrl":null,"linkName":"g522368g19c10.jpg","type":"GRAPHIC","id":"NTFILE3B3Dn7etHzWMsm1D","market":"us","size":130605},{"description":"GRAPHIC","seq":12,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518152964/g522368g20i14.jpg","primary":false,"translateUrl":null,"linkName":"g522368g20i14.jpg","type":"GRAPHIC","id":"NTFILE8BwRLtTvd7KcUmvx","market":"us","size":131580},{"description":"GRAPHIC","seq":13,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518152964/g522368g29x80.jpg","primary":false,"translateUrl":null,"linkName":"g522368g29x80.jpg","type":"GRAPHIC","id":"NTFILEAftBkaCZgg2NHj2p","market":"us","size":136035},{"description":"GRAPHIC","seq":14,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518152964/g522368g43z47.jpg","primary":false,"translateUrl":null,"linkName":"g522368g43z47.jpg","type":"GRAPHIC","id":"NTFILEFTp4GnbT8Q3MBW7K","market":"us","size":83256},{"description":"GRAPHIC","seq":15,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518152964/g522368g47p15.jpg","primary":false,"translateUrl":null,"linkName":"g522368g47p15.jpg","type":"GRAPHIC","id":"NTFILEweptjMXrnCfxoUhW","market":"us","size":159013},{"description":"GRAPHIC","seq":16,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518152964/g522368g73n73.jpg","primary":false,"translateUrl":null,"linkName":"g522368g73n73.jpg","type":"GRAPHIC","id":"NTFILEFRBfLnsBx4XyZKXb","market":"us","size":47677}],"type_name":"招股注册","type_name_en":"Recruitment Registration","titleTypeEn":"[Amend]Public Prospectus","us_type":"usProspectusesRegistrations","us_type_zh":"招股注册","earn_infos":[],"event_type":"important_notice","event_name":"[修订]招股说明书","pubTime":"2018-05-04 00:00","pubTimestamp":1525363200,"title_zh":"","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"4284749","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312518146797-ITRM","pdf_url":null,"pub_time":1525104000000,"showTitleType":true,"size":0,"source":"sec_us","summary":"","symbol":"ITRM","title":"","titleType":"SEC问询函","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518146797/0001193125-18-146797-index.htm","us_notice_code":"Form CORRESP","us_title_en":"[Cover]General form for registration of securities under the Securities Act of 1933","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"S-1","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518146797/d522368ds1.htm","primary":true,"translateUrl":null,"linkName":"d522368ds1.htm","type":"S-1","id":"NTFILEHtzCG7eLPn2Y1tm4","market":"us","size":1859895},{"description":"FORM OF UNDERWRITING AGREEMENT","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518146797/d522368dex11.htm","primary":false,"translateUrl":null,"linkName":"d522368dex11.htm","type":"EX-1.1","id":"NTFILEBaSTDxcKYXRUT9qz","market":"us","size":175578},{"description":"CONSTITUTION, AS CURRENTLY IN EFFECT","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518146797/d522368dex31.htm","primary":false,"translateUrl":null,"linkName":"d522368dex31.htm","type":"EX-3.1","id":"NTFILE8UoZD3rkdC13NX71","market":"us","size":294770},{"description":"FORM OF CONSTITUTION, POST - IPO","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518146797/d522368dex32.htm","primary":false,"translateUrl":null,"linkName":"d522368dex32.htm","type":"EX-3.2","id":"NTFILECPzp3H6AQvMwukdq","market":"us","size":436348},{"description":"FORM OF ORDINARY SHARE CERTIFICATE OF REGISTRANT","seq":5,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518146797/d522368dex41.htm","primary":false,"translateUrl":null,"linkName":"d522368dex41.htm","type":"EX-4.1","id":"NTFILEFY2Fh7QoNyF6sZqc","market":"us","size":31790},{"description":"FORM OF OPINION OF A&L GOODBODY","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518146797/d522368dex51.htm","primary":false,"translateUrl":null,"linkName":"d522368dex51.htm","type":"EX-5.1","id":"NTFILE4fpRxxSZDN72zuka","market":"us","size":27207},{"description":"PFIZER LICENSE AGREEMENT","seq":7,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518146797/d522368dex101.htm","primary":false,"translateUrl":null,"linkName":"d522368dex101.htm","type":"EX-10.1","id":"NTFILEDqZrhqRVMq1GzDYS","market":"us","size":335270},{"description":"AMENDED AND RESTATED INVESTOR RIGHTS AGREEMENT","seq":8,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518146797/d522368dex102.htm","primary":false,"translateUrl":null,"linkName":"d522368dex102.htm","type":"EX-10.2","id":"NTFILE7v64ArgkBQCKrHBo","market":"us","size":235904},{"description":"2015 EQUITY INCENTIVE PLAN","seq":9,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518146797/d522368dex103.htm","primary":false,"translateUrl":null,"linkName":"d522368dex103.htm","type":"EX-10.3","id":"NTFILEEoZhHSeKwhWuFs9Z","market":"us","size":108036},{"description":"FORMS OF 2015 U.S. STOCK OPTION AGR, GRANT NOTICE AND NOTICE OF EXERCISE","seq":10,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518146797/d522368dex104.htm","primary":false,"translateUrl":null,"linkName":"d522368dex104.htm","type":"EX-10.4","id":"NTFILEHivVSNE5zz7WLzFr","market":"us","size":82463},{"description":"FORMS OF 2015 IRISH STOCK OPTION AGR, GRANT NOTICE AND NOTICE OF EXERCISE","seq":11,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518146797/d522368dex105.htm","primary":false,"translateUrl":null,"linkName":"d522368dex105.htm","type":"EX-10.5","id":"NTFILE2C3yveSKYVvashTf","market":"us","size":85136},{"description":"2018 EQUITY INCENTIVE PLAN","seq":12,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518146797/d522368dex106.htm","primary":false,"translateUrl":null,"linkName":"d522368dex106.htm","type":"EX-10.6","id":"NTFILE4HsUpGJVvb5GJfxH","market":"us","size":152756},{"description":"FORMS OF 2018 U.S. STOCK OPTION TERMS AND CONDITIONS AND GRANT NOTICE","seq":13,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518146797/d522368dex107.htm","primary":false,"translateUrl":null,"linkName":"d522368dex107.htm","type":"EX-10.7","id":"NTFILEEtYJAtzZFEatXb4H","market":"us","size":43898},{"description":"FORMS OF 2018 INT'L STOCK OPTION TERMS AND CONDITIONS AND GRANT NOTICE","seq":14,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518146797/d522368dex108.htm","primary":false,"translateUrl":null,"linkName":"d522368dex108.htm","type":"EX-10.8","id":"NTFILEAoyjL4bzevmhEE4B","market":"us","size":54100},{"description":"FORM OF 2018 RESTRICTED SHARE UNIT AWARD AGREEMENT","seq":15,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518146797/d522368dex109.htm","primary":false,"translateUrl":null,"linkName":"d522368dex109.htm","type":"EX-10.9","id":"NTFILEETt6Vg7hwc1CeN97","market":"us","size":51486},{"description":"FORM OF INDEMNITY AGREEMENT (REGISTRANT)","seq":16,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518146797/d522368dex1010.htm","primary":false,"translateUrl":null,"linkName":"d522368dex1010.htm","type":"EX-10.10","id":"NTFILEEk1oWse1z5ypKPgh","market":"us","size":77239},{"description":"FORM OF INDEMNITY AGREEMENT (INTERUM THERAPEUTICS US LIMITED)","seq":17,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518146797/d522368dex1011.htm","primary":false,"translateUrl":null,"linkName":"d522368dex1011.htm","type":"EX-10.11","id":"NTFILEjMReHYxYUTRActeQ","market":"us","size":54687},{"description":"EMPLOYMENT TERMS - COREY N. FISHMAN","seq":18,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518146797/d522368dex1012.htm","primary":false,"translateUrl":null,"linkName":"d522368dex1012.htm","type":"EX-10.12","id":"NTFILE89HFRLqheizEABbh","market":"us","size":82726},{"description":"EMPLOYMENT TERMS - MICHAEL W. DUNNE","seq":19,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518146797/d522368dex1014.htm","primary":false,"translateUrl":null,"linkName":"d522368dex1014.htm","type":"EX-10.14","id":"NTFILE2SDbKyaoixBABM3p","market":"us","size":82199},{"description":"EMPLOYMENT TERMS - JUDITH M. MATTHEWS","seq":20,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518146797/d522368dex1015.htm","primary":false,"translateUrl":null,"linkName":"d522368dex1015.htm","type":"EX-10.15","id":"NTFILEFoNYseC3FpJ91Emm","market":"us","size":81754},{"description":"EMPLOYMENT TERMS - JEFFREY SCHAFFNIT","seq":21,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518146797/d522368dex1017.htm","primary":false,"translateUrl":null,"linkName":"d522368dex1017.htm","type":"EX-10.17","id":"NTFILEEmgh3WvoW9Kyb62e","market":"us","size":84840},{"description":"SUBSIDIARIES OF THE REGISTRANT","seq":22,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518146797/d522368dex211.htm","primary":false,"translateUrl":null,"linkName":"d522368dex211.htm","type":"EX-21.1","id":"NTFILECTM3J5n1db3gh5YD","market":"us","size":2424},{"description":"CONSENT OF KPMG","seq":23,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518146797/d522368dex231.htm","primary":false,"translateUrl":null,"linkName":"d522368dex231.htm","type":"EX-23.1","id":"NTFILEFyn99Yo4BkgKk3wy","market":"us","size":1966},{"description":"GRAPHIC","seq":25,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518146797/g522368dsp64.jpg","primary":false,"translateUrl":null,"linkName":"g522368dsp64.jpg","type":"GRAPHIC","id":"NTFILE4jk2ACS1KuquX8m6","market":"us","size":1000949},{"description":"GRAPHIC","seq":26,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518146797/g522368g0322073442413.jpg","primary":false,"translateUrl":null,"linkName":"g522368g0322073442413.jpg","type":"GRAPHIC","id":"NTFILEDs9w5z3C18SQC2Cx","market":"us","size":2253},{"description":"GRAPHIC","seq":27,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518146797/g522368g0420093516187.jpg","primary":false,"translateUrl":null,"linkName":"g522368g0420093516187.jpg","type":"GRAPHIC","id":"NTFILEGPNYuyZ6FzT9EXoX","market":"us","size":2411},{"description":"GRAPHIC","seq":28,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518146797/g522368g19c10.jpg","primary":false,"translateUrl":null,"linkName":"g522368g19c10.jpg","type":"GRAPHIC","id":"NTFILE9RDATU568AQ7AsuQ","market":"us","size":130605},{"description":"GRAPHIC","seq":29,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518146797/g522368g20i14.jpg","primary":false,"translateUrl":null,"linkName":"g522368g20i14.jpg","type":"GRAPHIC","id":"NTFILECyF9kFwSYrzV5NF8","market":"us","size":131580},{"description":"GRAPHIC","seq":30,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518146797/g522368g29x80.jpg","primary":false,"translateUrl":null,"linkName":"g522368g29x80.jpg","type":"GRAPHIC","id":"NTFILEBXc4u9EP4LneZ1xM","market":"us","size":136035},{"description":"GRAPHIC","seq":31,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518146797/g522368g43z47.jpg","primary":false,"translateUrl":null,"linkName":"g522368g43z47.jpg","type":"GRAPHIC","id":"NTFILEHAHvAjYMym3Ep6Q9","market":"us","size":83256},{"description":"GRAPHIC","seq":32,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518146797/g522368g47p15.jpg","primary":false,"translateUrl":null,"linkName":"g522368g47p15.jpg","type":"GRAPHIC","id":"NTFILEGw3SWopBj18Gprtm","market":"us","size":159013},{"description":"GRAPHIC","seq":33,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518146797/g522368g73n73.jpg","primary":false,"translateUrl":null,"linkName":"g522368g73n73.jpg","type":"GRAPHIC","id":"NTFILEBhBn3pUXZTczQQSe","market":"us","size":47677},{"description":"","seq":34,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1659323/000119312518146797/filename34.htm","primary":false,"translateUrl":null,"linkName":"filename34.htm","type":"CORRESP","id":"NTFILE3jrpsJSaDvYvQ1dH","market":"us","size":12550}],"type_name":"交易披露","type_name_en":"Transaction Related","titleTypeEn":"Correspondence","us_type":"usAnnouncement","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"SEC问询函","pubTime":"2018-05-01 00:00","pubTimestamp":1525104000,"title_zh":"","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0}],"pageSize":20,"totalPage":10,"pageCount":10,"totalSize":195,"code":"91000000","status":"200"}],"@#url:\"https://hq.skytigris.cn/fundamental/corporate_actions/details/ITRM\",params:#limit:5,,,undefined,":[{"market":"US","date":"2025-05-13","symbol":"ITRM","fiscalQuarterEnding":"2025/03","expectedEps":-0.14,"name":null,"time":"盘前","type":"earning","dateTimestamp":1747108800000,"reportTimeType":"pre","actualEps":-0.14},{"market":"US","date":"2025-02-07","symbol":"ITRM","fiscalQuarterEnding":"2024/12","expectedEps":-0.25,"name":null,"time":"盘前","type":"earning","dateTimestamp":1738904400000,"reportTimeType":"pre","actualEps":-0.12},{"market":"US","date":"2024-11-14","symbol":"ITRM","fiscalQuarterEnding":"2024/09","expectedEps":-0.23,"name":null,"time":"盘前","type":"earning","dateTimestamp":1731560400000,"reportTimeType":"pre","actualEps":-0.3},{"market":"US","date":"2024-08-14","symbol":"ITRM","fiscalQuarterEnding":"2024/06","expectedEps":-0.52,"name":null,"time":"盘前","type":"earning","dateTimestamp":1723608000000,"reportTimeType":"pre","actualEps":-0.3},{"market":"US","date":"2024-05-13","symbol":"ITRM","fiscalQuarterEnding":"2024/03","expectedEps":-0.57,"name":null,"time":"盘前","type":"earning","dateTimestamp":1715572800000,"reportTimeType":"pre","actualEps":-0.46}],"@#url:\"https://hq.skytigris.cn/fundamental/dividend/history\",params:#symbol:\"ITRM\",market:\"US\",,,undefined,":[],"@#url:\"https://hq.skytigris.cn/fundamental/estimate/recommendation\",params:#symbol:\"ITRM\",market:\"US\",delay:false,,,undefined,":{"strongBuy":0,"buy":1,"hold":0,"sell":0,"strongSell":0,"meanLabel":"BUY","meanPercent":1,"analysts":2,"updateTime":1746763200000},"@#url:\"https://hq.skytigris.cn/value_analysis/stock/ITRM\",params:#withQuantilePoint:true,period:\"5year\",factor:\"peRate\",delay:false,algorithm:1,,,undefined,":{"brief":{"id":"ITRM","date":"2025-07-15","current":-1.772735,"percent":0.177092,"low":-6.680036,"twenty":-1.698144,"median":-0.731459,"eighty":-0.275945,"high":16.020247,"avg":-0.492383,"sd":2.916416,"marketCap":40000000},"quantilePoints":[{"date":"2020-07-17","current":-0.236668,"twenty":-1.888466,"median":-1.117988,"eighty":-0.393882,"marketCap":23347305},{"date":"2020-07-24","current":-0.243123,"twenty":-1.886586,"median":-1.115978,"eighty":-0.388034,"marketCap":23984050},{"date":"2020-07-31","current":-0.223759,"twenty":-1.881572,"median":-1.109332,"eighty":-0.382547,"marketCap":22073817},{"date":"2020-08-07","current":-0.261888,"twenty":-1.867783,"median":-1.105971,"eighty":-0.381062,"marketCap":21876261},{"date":"2020-08-14","current":-0.228834,"twenty":-1.862142,"median":-1.100928,"eighty":-0.378258,"marketCap":19115180},{"date":"2020-08-21","current":-0.193746,"twenty":-1.859008,"median":-1.09639,"eighty":-0.371643,"marketCap":16184185},{"date":"2020-08-28","current":-0.192475,"twenty":-1.838324,"median":-1.095045,"eighty":-0.367501,"marketCap":16077990},{"date":"2020-09-04","current":-0.151285,"twenty":-1.825789,"median":-1.092524,"eighty":-0.359305,"marketCap":12637257},{"date":"2020-09-11","current":-0.152556,"twenty":-1.814507,"median":-1.092524,"eighty":-0.356251,"marketCap":12743452},{"date":"2020-09-18","current":-0.167481,"twenty":-1.807257,"median":-1.090002,"eighty":-0.34827,"marketCap":13990188},{"date":"2020-09-25","current":-0.165269,"twenty":-1.803824,"median":-1.085818,"eighty":-0.34483,"marketCap":13805407},{"date":"2020-10-02","current":-0.269515,"twenty":-1.801972,"median":-1.077397,"eighty":-0.341727,"marketCap":22513434},{"date":"2020-10-09","current":-0.261888,"twenty":-1.800092,"median":-1.058908,"eighty":-0.337509,"marketCap":21876261},{"date":"2020-10-16","current":-0.227563,"twenty":-1.781626,"median":-1.052185,"eighty":-0.331628,"marketCap":19008984},{"date":"2020-10-23","current":-0.217878,"twenty":-1.750859,"median":-1.030939,"eighty":-0.329328,"marketCap":18200020},{"date":"2020-10-30","current":-0.196601,"twenty":-1.731138,"median":-1.019128,"eighty":-0.308427,"marketCap":16422633},{"date":"2020-11-06","current":-0.20697,"twenty":-1.715587,"median":-1.001315,"eighty":-0.303103,"marketCap":17288806},{"date":"2020-11-13","current":-0.21568,"twenty":-1.706787,"median":-0.992427,"eighty":-0.293674,"marketCap":18016391},{"date":"2020-11-20","current":-0.357976,"twenty":-1.700361,"median":-0.961321,"eighty":-0.295814,"marketCap":23075489},{"date":"2020-11-27","current":-0.509124,"twenty":-1.696735,"median":-0.952434,"eighty":-0.298394,"marketCap":32818668},{"date":"2020-12-04","current":-0.562467,"twenty":-1.695527,"median":-0.94799,"eighty":-0.301392,"marketCap":36257182},{"date":"2020-12-11","current":-0.619014,"twenty":-1.693133,"median":-0.934659,"eighty":-0.302741,"marketCap":39902268},{"date":"2020-12-18","current":-0.676599,"twenty":-1.690431,"median":-0.9322,"eighty":-0.30434,"marketCap":43614258},{"date":"2020-12-24","current":-0.763536,"twenty":-1.683113,"median":-0.930215,"eighty":-0.305221,"marketCap":49218324},{"date":"2020-12-31","current":-0.753031,"twenty":-1.664819,"median":-0.928305,"eighty":-0.305655,"marketCap":48541132},{"date":"2021-01-08","current":-0.93653,"twenty":-1.662532,"median":-0.927371,"eighty":-0.306707,"marketCap":60369658},{"date":"2021-01-15","current":-0.921302,"twenty":-1.653421,"median":-0.926535,"eighty":-0.309573,"marketCap":59388037},{"date":"2021-01-22","current":-1.446672,"twenty":-1.651563,"median":-0.927401,"eighty":-0.318746,"marketCap":93253945},{"date":"2021-01-29","current":-1.073583,"twenty":-1.627942,"median":-0.930215,"eighty":-0.324478,"marketCap":69204244},{"date":"2021-02-05","current":-2.391993,"twenty":-1.662989,"median":-0.9322,"eighty":-0.328159,"marketCap":154190240},{"date":"2021-02-12","current":-5.529993,"twenty":-1.694318,"median":-0.934659,"eighty":-0.329483,"marketCap":356468898},{"date":"2021-02-19","current":-5.065082,"twenty":-1.706787,"median":-0.93653,"eighty":-0.330044,"marketCap":326500269},{"date":"2021-02-26","current":-4.012915,"twenty":-1.781626,"median":-0.94799,"eighty":-0.331628,"marketCap":258676538},{"date":"2021-03-05","current":-3.694818,"twenty":-1.807257,"median":-0.952434,"eighty":-0.332831,"marketCap":238171690},{"date":"2021-03-12","current":-5.259794,"twenty":-1.846148,"median":-0.961321,"eighty":-0.333582,"marketCap":273540828},{"date":"2021-03-19","current":-5.667003,"twenty":-1.877583,"median":-0.992427,"eighty":-0.335422,"marketCap":294718182},{"date":"2021-03-26","current":-4.784715,"twenty":-1.898495,"median":-1.000574,"eighty":-0.336415,"marketCap":248833914},{"date":"2021-04-01","current":-4.954386,"twenty":-1.911657,"median":-1.011313,"eighty":-0.337145,"marketCap":257657816},{"date":"2021-04-09","current":-4.479308,"twenty":-1.951956,"median":-1.023914,"eighty":-0.338237,"marketCap":232950901},{"date":"2021-04-16","current":-3.732757,"twenty":-1.983736,"median":-1.050623,"eighty":-0.339028,"marketCap":194125743},{"date":"2021-04-23","current":-4.072098,"twenty":-2.022596,"median":-1.052185,"eighty":-0.340323,"marketCap":211773548},{"date":"2021-04-30","current":-4.236832,"twenty":-2.099062,"median":-1.06311,"eighty":-0.340564,"marketCap":220340666},{"date":"2021-05-07","current":-3.685699,"twenty":-2.126013,"median":-1.073583,"eighty":-0.341379,"marketCap":191678462},{"date":"2021-05-14","current":-1.395089,"twenty":-2.32094,"median":-1.084969,"eighty":-0.342468,"marketCap":188095696},{"date":"2021-05-21","current":-1.514668,"twenty":-2.230057,"median":-1.088811,"eighty":-0.34311,"marketCap":204218181},{"date":"2021-05-28","current":-1.926552,"twenty":-2.144189,"median":-1.091675,"eighty":-0.34397,"marketCap":259751201},{"date":"2021-06-04","current":-2.12585,"twenty":-2.129992,"median":-1.092524,"eighty":-0.344257,"marketCap":286622016},{"date":"2021-06-11","current":-2.497874,"twenty":-2.30578,"median":-1.092927,"eighty":-0.345495,"marketCap":336780858},{"date":"2021-06-18","current":-2.697172,"twenty":-2.389253,"median":-1.09597,"eighty":-0.345895,"marketCap":363651674},{"date":"2021-06-25","current":-2.750319,"twenty":-2.62367,"median":-1.097113,"eighty":-0.346252,"marketCap":370817228},{"date":"2021-07-02","current":-1.886692,"twenty":-2.642337,"median":-1.103449,"eighty":-0.347161,"marketCap":254377035},{"date":"2021-07-09","current":-1.74054,"twenty":-2.635579,"median":-1.106811,"eighty":-0.347161,"marketCap":234671774},{"date":"2021-07-16","current":-1.541241,"twenty":-2.635579,"median":-1.109332,"eighty":-0.34827,"marketCap":207800958},{"date":"2021-07-23","current":-1.501382,"twenty":-2.632445,"median":-1.116016,"eighty":-0.34827,"marketCap":202426793},{"date":"2021-07-30","current":-1.03489,"twenty":-2.588571,"median":-1.11577,"eighty":-0.34827,"marketCap":139531178},{"date":"2021-08-06","current":-1.030506,"twenty":-2.537734,"median":-1.108491,"eighty":-0.355436,"marketCap":138940020},{"date":"2021-08-13","current":-1.113016,"twenty":-2.497874,"median":-1.105971,"eighty":-0.355436,"marketCap":127449185},{"date":"2021-08-20","current":-1.003837,"twenty":-2.391993,"median":-1.100928,"eighty":-0.356795,"marketCap":114947362},{"date":"2021-08-27","current":-1.070078,"twenty":-2.378295,"median":-1.097113,"eighty":-0.356869,"marketCap":122532528},{"date":"2021-09-03","current":-1.087317,"twenty":-2.365008,"median":-1.096751,"eighty":-0.357586,"marketCap":124506502},{"date":"2021-09-10","current":-1.035601,"twenty":-2.350813,"median":-1.09597,"eighty":-0.357898,"marketCap":118584592},{"date":"2021-09-17","current":-0.99857,"twenty":-2.318942,"median":-1.092927,"eighty":-0.359383,"marketCap":114344204},{"date":"2021-09-24","current":-0.859383,"twenty":-2.287535,"median":-1.092524,"eighty":-0.363175,"marketCap":98406192},{"date":"2021-10-01","current":-0.959463,"twenty":-2.231375,"median":-1.091786,"eighty":-0.364621,"marketCap":109866207},{"date":"2021-10-08","current":-0.848369,"twenty":-2.166142,"median":-1.088986,"eighty":-0.366474,"marketCap":97145055},{"date":"2021-10-15","current":-0.878856,"twenty":-2.135414,"median":-1.087317,"eighty":-0.367501,"marketCap":100636052},{"date":"2021-10-22","current":-0.833365,"twenty":-2.126885,"median":-1.08412,"eighty":-0.368198,"marketCap":95426966},{"date":"2021-10-29","current":-0.852359,"twenty":-2.119964,"median":-1.081092,"eighty":-0.368357,"marketCap":97601981},{"date":"2021-11-05","current":-0.900245,"twenty":-2.115985,"median":-1.076623,"eighty":-0.36992,"marketCap":103085242},{"date":"2021-11-12","current":-1.053246,"twenty":-2.107887,"median":-1.071355,"eighty":-0.371643,"marketCap":103816343},{"date":"2021-11-19","current":-0.917882,"twenty":-2.103462,"median":-1.069759,"eighty":-0.374283,"marketCap":90473754},{"date":"2021-11-26","current":-0.904716,"twenty":-2.097182,"median":-1.065981,"eighty":-0.375245,"marketCap":89176049},{"date":"2021-12-03","current":-0.797352,"twenty":-2.083079,"median":-1.058908,"eighty":-0.376894,"marketCap":78593356},{"date":"2021-12-10","current":-0.89767,"twenty":-2.071484,"median":-1.054365,"eighty":-0.378149,"marketCap":88481503},{"date":"2021-12-17","current":-0.880795,"twenty":-2.055019,"median":-1.052185,"eighty":-0.378367,"marketCap":86818247},{"date":"2021-12-23","current":-0.849087,"twenty":-2.04123,"median":-1.050741,"eighty":-0.379271,"marketCap":83692788},{"date":"2021-12-31","current":-0.726517,"twenty":-2.02815,"median":-1.040629,"eighty":-0.380778,"marketCap":71611349},{"date":"2022-01-07","current":-0.756186,"twenty":-2.014243,"median":-1.03489,"eighty":-0.381033,"marketCap":74535743},{"date":"2022-01-14","current":-0.723179,"twenty":-2.006032,"median":-1.02721,"eighty":-0.381139,"marketCap":71282353},{"date":"2022-01-21","current":-0.619524,"twenty":-2.005673,"median":-1.023338,"eighty":-0.381234,"marketCap":61065211},{"date":"2022-01-28","current":-0.593378,"twenty":-2.004419,"median":-1.014646,"eighty":-0.381401,"marketCap":58488078},{"date":"2022-02-04","current":-0.752107,"twenty":-1.996271,"median":-1.007434,"eighty":-0.382189,"marketCap":74133637},{"date":"2022-02-11","current":-0.759895,"twenty":-1.983736,"median":-1.001315,"eighty":-0.38291,"marketCap":74901293},{"date":"2022-02-18","current":-0.67812,"twenty":-1.978095,"median":-0.997929,"eighty":-0.384094,"marketCap":66840912},{"date":"2022-02-25","current":-0.686093,"twenty":-1.955531,"median":-0.993423,"eighty":-0.384952,"marketCap":67626846},{"date":"2022-03-04","current":-0.682014,"twenty":-1.955531,"median":-0.989828,"eighty":-0.385673,"marketCap":67224740},{"date":"2022-03-11","current":-0.695365,"twenty":-1.952397,"median":-0.982533,"eighty":-0.387836,"marketCap":68540723},{"date":"2022-03-18","current":-0.778809,"twenty":-1.951294,"median":-0.973829,"eighty":-0.388084,"marketCap":76765602},{"date":"2022-03-25","current":-0.830358,"twenty":-1.942995,"median":-0.966633,"eighty":-0.390719,"marketCap":81846757},{"date":"2022-04-01","current":-0.714621,"twenty":-1.926552,"median":-0.961321,"eighty":-0.391266,"marketCap":65433542},{"date":"2022-04-08","current":-0.635982,"twenty":-1.924192,"median":-0.958984,"eighty":-0.392882,"marketCap":58233036},{"date":"2022-04-14","current":-0.614555,"twenty":-1.914164,"median":-0.953915,"eighty":-0.393834,"marketCap":56271154},{"date":"2022-04-22","current":-0.562692,"twenty":-1.911657,"median":-0.949472,"eighty":-0.39412,"marketCap":51522298},{"date":"2022-04-29","current":-0.508225,"twenty":-1.910403,"median":-0.942806,"eighty":-0.394132,"marketCap":46535095},{"date":"2022-05-06","current":-0.496811,"twenty":-1.903822,"median":-0.93653,"eighty":-0.394132,"marketCap":45489980},{"date":"2022-05-13","current":10.391768,"twenty":-1.897241,"median":-0.934851,"eighty":-0.394132,"marketCap":40081051},{"date":"2022-05-20","current":12.835211,"twenty":-1.888551,"median":-0.933643,"eighty":-0.391157,"marketCap":49505409},{"date":"2022-05-27","current":10.61995,"twenty":-1.886607,"median":-0.9322,"eighty":-0.385529,"marketCap":40961148},{"date":"2022-06-03","current":10.458321,"twenty":-1.886586,"median":-0.930215,"eighty":-0.382588,"marketCap":40337746},{"date":"2022-06-10","current":10.966977,"twenty":-1.882825,"median":-0.928338,"eighty":-0.381171,"marketCap":42299629},{"date":"2022-06-17","current":9.7405,"twenty":-1.877583,"median":-0.927386,"eighty":-0.378367,"marketCap":37569108},{"date":"2022-06-24","current":9.474288,"twenty":-1.871316,"median":-0.926535,"eighty":-0.375116,"marketCap":36542329},{"date":"2022-07-01","current":10.144572,"twenty":-1.863395,"median":-0.923709,"eighty":-0.368346,"marketCap":39127613},{"date":"2022-07-08","current":11.409079,"twenty":-1.860888,"median":-0.92159,"eighty":-0.365195,"marketCap":44004816},{"date":"2022-07-15","current":12.692598,"twenty":-1.854303,"median":-0.919647,"eighty":-0.357664,"marketCap":48955349},{"date":"2022-07-22","current":11.632507,"twenty":-1.837056,"median":-0.917882,"eighty":-0.355436,"marketCap":44866578},{"date":"2022-07-29","current":10.458321,"twenty":-1.83143,"median":-0.915745,"eighty":-0.347383,"marketCap":40337746},{"date":"2022-08-05","current":12.357459,"twenty":-1.820775,"median":-0.910464,"eighty":-0.345495,"marketCap":47662719},{"date":"2022-08-12","current":-4.470636,"twenty":-1.820775,"median":-0.907552,"eighty":-0.342824,"marketCap":47728507},{"date":"2022-08-19","current":-3.116785,"twenty":-1.860888,"median":-0.911577,"eighty":-0.34397,"marketCap":33274793},{"date":"2022-08-26","current":-3.093867,"twenty":-1.885332,"median":-0.917843,"eighty":-0.344257,"marketCap":33030126},{"date":"2022-09-02","current":-2.795939,"twenty":-1.901002,"median":-0.918366,"eighty":-0.345495,"marketCap":29849447},{"date":"2022-09-09","current":-2.69281,"twenty":-1.911657,"median":-0.919736,"eighty":-0.345862,"marketCap":28748443},{"date":"2022-09-16","current":-2.200083,"twenty":-1.951294,"median":-0.9222,"eighty":-0.346025,"marketCap":23488089},{"date":"2022-09-23","current":-1.821944,"twenty":-1.955531,"median":-0.925772,"eighty":-0.347161,"marketCap":19451074},{"date":"2022-09-30","current":-1.85632,"twenty":-1.970908,"median":-0.927253,"eighty":-0.347161,"marketCap":19818075},{"date":"2022-10-07","current":-2.096953,"twenty":-1.983736,"median":-0.927431,"eighty":-0.34827,"marketCap":22387074},{"date":"2022-10-14","current":-1.890696,"twenty":-1.983736,"median":-0.929697,"eighty":-0.34827,"marketCap":20185067},{"date":"2022-10-21","current":-2.096953,"twenty":-2.005283,"median":-0.931223,"eighty":-0.34827,"marketCap":22387074},{"date":"2022-10-28","current":-1.925072,"twenty":-2.006271,"median":-0.933624,"eighty":-0.355436,"marketCap":20552068},{"date":"2022-11-04","current":-1.844861,"twenty":-2.005673,"median":-0.934659,"eighty":-0.355436,"marketCap":19695732},{"date":"2022-11-11","current":-0.420183,"twenty":-2.005673,"median":-0.934851,"eighty":-0.356795,"marketCap":18288894},{"date":"2022-11-18","current":-0.370998,"twenty":-2.005283,"median":-0.933643,"eighty":-0.356869,"marketCap":16148053},{"date":"2022-11-25","current":-0.373808,"twenty":-2.000581,"median":-0.933178,"eighty":-0.356854,"marketCap":16270387},{"date":"2022-12-02","current":-0.390672,"twenty":-1.994941,"median":-0.930215,"eighty":-0.35693,"marketCap":17004389},{"date":"2022-12-09","current":-0.333055,"twenty":-1.985754,"median":-0.928338,"eighty":-0.356523,"marketCap":14496548},{"date":"2022-12-16","current":-0.306354,"twenty":-1.983736,"median":-0.927386,"eighty":-0.34827,"marketCap":13334377},{"date":"2022-12-23","current":-0.230581,"twenty":-1.982641,"median":-0.925935,"eighty":-0.346934,"marketCap":10036260},{"date":"2022-12-30","current":-0.23609,"twenty":-1.975492,"median":-0.923709,"eighty":-0.34483,"marketCap":10276034},{"date":"2023-01-06","current":-0.261385,"twenty":-1.966324,"median":-0.92159,"eighty":-0.342679,"marketCap":11377037},{"date":"2023-01-13","current":-0.337271,"twenty":-1.957881,"median":-0.919647,"eighty":-0.340323,"marketCap":14680048},{"date":"2023-01-20","current":-0.33165,"twenty":-1.955531,"median":-0.918124,"eighty":-0.340108,"marketCap":14435381},{"date":"2023-01-27","current":-0.340081,"twenty":-1.954904,"median":-0.917803,"eighty":-0.338237,"marketCap":14802382},{"date":"2023-02-03","current":-0.414562,"twenty":-1.952176,"median":-0.911021,"eighty":-0.338606,"marketCap":18044226},{"date":"2023-02-10","current":-0.359756,"twenty":-1.949634,"median":-0.907108,"eighty":-0.340081,"marketCap":15658718},{"date":"2023-02-17","current":-0.351324,"twenty":-1.941702,"median":-0.903394,"eighty":-0.340081,"marketCap":15291717},{"date":"2023-02-24","current":-0.323218,"twenty":-1.936531,"median":-0.900719,"eighty":-0.340081,"marketCap":14068380},{"date":"2023-03-03","current":-0.342892,"twenty":-1.926552,"median":-0.898808,"eighty":-0.337271,"marketCap":14924716},{"date":"2023-03-10","current":-0.28024,"twenty":-1.925072,"median":-0.894339,"eighty":-0.335704,"marketCap":12197722},{"date":"2023-03-17","current":-0.309341,"twenty":-1.924192,"median":-0.890827,"eighty":-0.333055,"marketCap":13745269},{"date":"2023-03-24","current":-0.274913,"twenty":-1.923468,"median":-0.885719,"eighty":-0.33165,"marketCap":12215471},{"date":"2023-03-31","current":-0.286398,"twenty":-1.913613,"median":-0.883232,"eighty":-0.329391,"marketCap":12725828},{"date":"2023-04-06","current":-0.283563,"twenty":-1.912048,"median":-0.882816,"eighty":-0.328277,"marketCap":12599829},{"date":"2023-04-14","current":-0.310115,"twenty":-1.911657,"median":-0.881023,"eighty":-0.323218,"marketCap":13779632},{"date":"2023-04-21","current":-0.323663,"twenty":-1.910403,"median":-0.879973,"eighty":-0.323218,"marketCap":14381624},{"date":"2023-04-28","current":-0.305045,"twenty":-1.903822,"median":-0.876667,"eighty":-0.320913,"marketCap":13554362},{"date":"2023-05-05","current":-0.309341,"twenty":-1.902174,"median":-0.868003,"eighty":-0.320407,"marketCap":13745269},{"date":"2023-05-12","current":-0.323663,"twenty":-1.897221,"median":-0.862764,"eighty":-0.320407,"marketCap":14381624},{"date":"2023-05-19","current":-0.275487,"twenty":-1.891755,"median":-0.855552,"eighty":-0.317867,"marketCap":14001083},{"date":"2023-05-26","current":-0.295496,"twenty":-1.890696,"median":-0.853796,"eighty":-0.31507,"marketCap":15017979},{"date":"2023-06-02","current":-0.298,"twenty":-1.882825,"median":-0.852359,"eighty":-0.309341,"marketCap":15145250},{"date":"2023-06-09","current":-0.280811,"twenty":-1.865901,"median":-0.848901,"eighty":-0.306498,"marketCap":14271645},{"date":"2023-06-16","current":-0.283364,"twenty":-1.849444,"median":-0.841855,"eighty":-0.304557,"marketCap":14401387},{"date":"2023-06-23","current":-0.273152,"twenty":-1.823123,"median":-0.828782,"eighty":-0.300381,"marketCap":13882418},{"date":"2023-06-30","current":-0.280811,"twenty":-1.801345,"median":-0.81404,"eighty":-0.295732,"marketCap":14271645},{"date":"2023-07-07","current":-0.280811,"twenty":-1.740032,"median":-0.786411,"eighty":-0.294528,"marketCap":14271645},{"date":"2023-07-14","current":-0.298681,"twenty":-1.699891,"median":-0.778809,"eighty":-0.292634,"marketCap":15179840},{"date":"2023-07-21","current":-0.288469,"twenty":-1.684971,"median":-0.763536,"eighty":-0.291022,"marketCap":14660871},{"date":"2023-07-28","current":-0.268047,"twenty":-1.647728,"median":-0.760265,"eighty":-0.288633,"marketCap":13622934},{"date":"2023-08-04","current":-0.255283,"twenty":-1.613427,"median":-0.753031,"eighty":-0.287637,"marketCap":12974223},{"date":"2023-08-11","current":-0.257835,"twenty":-1.594388,"median":-0.743577,"eighty":-0.286404,"marketCap":13103965},{"date":"2023-08-18","current":-0.229146,"twenty":-1.584334,"median":-0.738589,"eighty":-0.285726,"marketCap":12908022},{"date":"2023-08-25","current":-0.208357,"twenty":-1.566485,"median":-0.726888,"eighty":-0.283696,"marketCap":11736936},{"date":"2023-09-01","current":-0.203726,"twenty":-1.544971,"median":-0.723179,"eighty":-0.283364,"marketCap":11476116},{"date":"2023-09-08","current":-0.189836,"twenty":-1.534444,"median":-0.713908,"eighty":-0.280846,"marketCap":10693653},{"date":"2023-09-15","current":-0.182449,"twenty":-1.514668,"median":-0.704451,"eighty":-0.280811,"marketCap":10277553},{"date":"2023-09-22","current":-0.16731,"twenty":-1.509722,"median":-0.695059,"eighty":-0.278854,"marketCap":9424760},{"date":"2023-09-29","current":-0.160921,"twenty":-1.500249,"median":-0.686093,"eighty":-0.277846,"marketCap":9064827},{"date":"2023-10-06","current":-0.166755,"twenty":-1.490927,"median":-0.678406,"eighty":-0.275975,"marketCap":9393461},{"date":"2023-10-13","current":-0.175946,"twenty":-1.484626,"median":-0.663576,"eighty":-0.274204,"marketCap":9911191},{"date":"2023-10-20","current":-0.155341,"twenty":-1.465635,"median":-0.650677,"eighty":-0.272996,"marketCap":8750538},{"date":"2023-10-27","current":-0.15511,"twenty":-1.449813,"median":-0.646266,"eighty":-0.271773,"marketCap":8737497},{"date":"2023-11-03","current":-0.173631,"twenty":-1.432476,"median":-0.639288,"eighty":-0.270165,"marketCap":9780780},{"date":"2023-11-10","current":-0.180043,"twenty":-1.395957,"median":-0.635193,"eighty":-0.267383,"marketCap":10142017},{"date":"2023-11-17","current":-0.494821,"twenty":-1.384223,"median":-0.626936,"eighty":-0.264834,"marketCap":15388428},{"date":"2023-11-24","current":-0.965144,"twenty":-1.378861,"median":-0.625606,"eighty":-0.264834,"marketCap":30015016},{"date":"2023-12-01","current":-0.7889,"twenty":-1.37209,"median":-0.625606,"eighty":-0.264834,"marketCap":24534013},{"date":"2023-12-08","current":-0.71625,"twenty":-1.363151,"median":-0.626312,"eighty":-0.265164,"marketCap":22274671},{"date":"2023-12-15","current":-0.750768,"twenty":-1.338258,"median":-0.626312,"eighty":-0.265164,"marketCap":23348149},{"date":"2023-12-22","current":-0.699872,"twenty":-1.325151,"median":-0.626312,"eighty":-0.265164,"marketCap":21765328},{"date":"2023-12-29","current":-0.86404,"twenty":-1.325455,"median":-0.62489,"eighty":-0.264834,"marketCap":26870776},{"date":"2024-01-05","current":-0.86404,"twenty":-1.323937,"median":-0.624879,"eighty":-0.264504,"marketCap":26870776},{"date":"2024-01-12","current":-0.838119,"twenty":-1.315847,"median":-0.624879,"eighty":-0.264504,"marketCap":26064652},{"date":"2024-01-19","current":-0.816518,"twenty":-1.292641,"median":-0.623221,"eighty":-0.264174,"marketCap":25392883},{"date":"2024-01-26","current":-0.717196,"twenty":-1.26325,"median":-0.624879,"eighty":-0.264504,"marketCap":22304087},{"date":"2024-02-02","current":-0.665311,"twenty":-1.237165,"median":-0.624879,"eighty":-0.264504,"marketCap":20690497},{"date":"2024-02-09","current":-0.686912,"twenty":-1.207317,"median":-0.621563,"eighty":-0.264504,"marketCap":21362266},{"date":"2024-02-16","current":-0.64803,"twenty":-1.189604,"median":-0.621563,"eighty":-0.264504,"marketCap":20153082},{"date":"2024-02-23","current":-0.583227,"twenty":-1.180968,"median":-0.619524,"eighty":-0.264504,"marketCap":18137773},{"date":"2024-03-01","current":-0.535705,"twenty":-1.15508,"median":-0.614011,"eighty":-0.264834,"marketCap":16659881},{"date":"2024-03-08","current":-0.65235,"twenty":-1.141859,"median":-0.60742,"eighty":-0.264834,"marketCap":20287435},{"date":"2024-03-15","current":-0.626429,"twenty":-1.135216,"median":-0.60742,"eighty":-0.264834,"marketCap":19481312},{"date":"2024-03-22","current":-0.682591,"twenty":-1.130927,"median":-0.60742,"eighty":-0.264834,"marketCap":21227913},{"date":"2024-03-28","current":-0.686912,"twenty":-1.121064,"median":-0.60742,"eighty":-0.264834,"marketCap":21362266},{"date":"2024-04-05","current":-0.65477,"twenty":-1.113495,"median":-0.600738,"eighty":-0.264504,"marketCap":25124175},{"date":"2024-04-12","current":-0.702091,"twenty":-1.105971,"median":-0.600738,"eighty":-0.264504,"marketCap":26939925},{"date":"2024-04-19","current":-0.612189,"twenty":-1.096824,"median":-0.600738,"eighty":-0.264504,"marketCap":23490301},{"date":"2024-04-26","current":-0.672123,"twenty":-1.093438,"median":-0.600796,"eighty":-0.264834,"marketCap":25790050},{"date":"2024-05-03","current":-0.681679,"twenty":-1.092074,"median":-0.600796,"eighty":-0.264834,"marketCap":26156718},{"date":"2024-05-10","current":-0.694623,"twenty":-1.087383,"median":-0.600796,"eighty":-0.264834,"marketCap":26653364},{"date":"2024-05-17","current":-0.688566,"twenty":-1.079758,"median":-0.600796,"eighty":-0.264834,"marketCap":24501229},{"date":"2024-05-24","current":-0.646693,"twenty":-1.072246,"median":-0.600796,"eighty":-0.264834,"marketCap":23011290},{"date":"2024-05-31","current":-0.600169,"twenty":-1.069695,"median":-0.600169,"eighty":-0.264834,"marketCap":21355801},{"date":"2024-06-07","current":-0.655998,"twenty":-1.065715,"median":-0.600169,"eighty":-0.264834,"marketCap":23342387},{"date":"2024-06-14","current":-0.544339,"twenty":-1.052244,"median":-0.593378,"eighty":-0.264504,"marketCap":19369215},{"date":"2024-06-21","current":-0.535034,"twenty":-1.035331,"median":-0.584158,"eighty":-0.264174,"marketCap":19038117},{"date":"2024-06-28","current":-0.558296,"twenty":-1.026041,"median":-0.577583,"eighty":-0.263763,"marketCap":19865862},{"date":"2024-07-05","current":-0.521077,"twenty":-1.009337,"median":-0.574706,"eighty":-0.263763,"marketCap":18541471},{"date":"2024-07-12","current":-0.746721,"twenty":-0.999075,"median":-0.574237,"eighty":-0.263763,"marketCap":26570590},{"date":"2024-07-15","current":-0.763005,"twenty":-0.997801,"median":-0.574237,"eighty":-0.263763,"marketCap":27150011},{"date":"2024-08-02","current":-0.544339,"twenty":-0.969653,"median":-0.561546,"eighty":-0.262941,"marketCap":19369215},{"date":"2024-08-09","current":-0.747354,"twenty":-0.961321,"median":-0.561546,"eighty":-0.262941,"marketCap":26593098},{"date":"2024-08-16","current":-0.977567,"twenty":-0.955396,"median":-0.559264,"eighty":-0.262941,"marketCap":27701312},{"date":"2024-08-23","current":-0.969554,"twenty":-0.958505,"median":-0.559264,"eighty":-0.262941,"marketCap":27474252},{"date":"2024-08-30","current":-0.905451,"twenty":-0.959463,"median":-0.559264,"eighty":-0.262941,"marketCap":25657773},{"date":"2024-09-06","current":-0.897438,"twenty":-0.959463,"median":-0.559264,"eighty":-0.262941,"marketCap":25430713},{"date":"2024-09-13","current":-0.889426,"twenty":-0.955396,"median":-0.559264,"eighty":-0.262941,"marketCap":25203653},{"date":"2024-09-20","current":-0.8734,"twenty":-0.945515,"median":-0.559264,"eighty":-0.262941,"marketCap":24749533},{"date":"2024-09-27","current":-0.837342,"twenty":-0.945515,"median":-0.559264,"eighty":-0.262941,"marketCap":23727763},{"date":"2024-10-04","current":-0.798079,"twenty":-0.945515,"median":-0.559264,"eighty":-0.262941,"marketCap":22615170},{"date":"2024-10-11","current":-0.745114,"twenty":-0.945515,"median":-0.559264,"eighty":-0.262941,"marketCap":21114303},{"date":"2024-10-18","current":-0.8734,"twenty":-0.945515,"median":-0.559264,"eighty":-0.262941,"marketCap":24749533},{"date":"2024-10-25","current":-0.937503,"twenty":-0.945515,"median":-0.56258,"eighty":-0.262941,"marketCap":26566012},{"date":"2024-10-31","current":-0.969554,"twenty":-0.962496,"median":-0.57105,"eighty":-0.262941,"marketCap":27474252},{"date":"2024-11-08","current":-1.04167,"twenty":-0.969554,"median":-0.577583,"eighty":-0.26285,"marketCap":29517792},{"date":"2024-11-15","current":-1.089747,"twenty":-0.974916,"median":-0.593378,"eighty":-0.26285,"marketCap":30880151},{"date":"2024-11-22","current":-1.315363,"twenty":-0.985278,"median":-0.600855,"eighty":-0.262941,"marketCap":40189609},{"date":"2024-11-29","current":-1.819145,"twenty":-0.997545,"median":-0.604828,"eighty":-0.262941,"marketCap":55582170},{"date":"2024-12-06","current":-2.55761,"twenty":-1.019015,"median":-0.612189,"eighty":-0.262941,"marketCap":78145229},{"date":"2024-12-13","current":-1.783123,"twenty":-1.033904,"median":-0.614847,"eighty":-0.262941,"marketCap":54481533},{"date":"2024-12-20","current":-1.575992,"twenty":-1.045661,"median":-0.621563,"eighty":-0.262941,"marketCap":48152870},{"date":"2024-12-27","current":-1.801134,"twenty":-1.055307,"median":-0.624901,"eighty":-0.262941,"marketCap":55031852},{"date":"2025-01-03","current":-1.648038,"twenty":-1.062225,"median":-0.625032,"eighty":-0.262941,"marketCap":50354144},{"date":"2025-01-10","current":-1.621021,"twenty":-1.072246,"median":-0.625672,"eighty":-0.262941,"marketCap":49528666},{"date":"2025-01-17","current":-1.386873,"twenty":-1.078,"median":-0.628083,"eighty":-0.262941,"marketCap":42374526},{"date":"2025-01-24","current":-1.350851,"twenty":-1.089185,"median":-0.63481,"eighty":-0.262941,"marketCap":41273889},{"date":"2025-01-31","current":-1.41389,"twenty":-1.113797,"median":-0.637774,"eighty":-0.262941,"marketCap":43200003},{"date":"2025-02-07","current":-1.341845,"twenty":-1.145837,"median":-0.642875,"eighty":-0.262941,"marketCap":40998729},{"date":"2025-02-14","current":-2.093812,"twenty":-1.194605,"median":-0.649778,"eighty":-0.262941,"marketCap":51872107},{"date":"2025-02-21","current":-2.079854,"twenty":-1.331646,"median":-0.65467,"eighty":-0.262941,"marketCap":51526293},{"date":"2025-02-28","current":-1.908161,"twenty":-1.358055,"median":-0.658389,"eighty":-0.262941,"marketCap":47272780},{"date":"2025-03-07","current":-1.912349,"twenty":-1.386873,"median":-0.665303,"eighty":-0.262941,"marketCap":47376524},{"date":"2025-03-14","current":-1.870472,"twenty":-1.41389,"median":-0.669631,"eighty":-0.262941,"marketCap":46339082},{"date":"2025-03-21","current":-2.024019,"twenty":-1.444366,"median":-0.673951,"eighty":-0.267246,"marketCap":50143037},{"date":"2025-03-28","current":-1.800679,"twenty":-1.487231,"median":-0.676405,"eighty":-0.267246,"marketCap":44610012},{"date":"2025-04-04","current":-1.633174,"twenty":-1.501382,"median":-0.681087,"eighty":-0.267246,"marketCap":40460243},{"date":"2025-04-11","current":-1.535462,"twenty":-1.522986,"median":-0.682591,"eighty":-0.267383,"marketCap":38039545},{"date":"2025-04-17","current":-1.465669,"twenty":-1.544513,"median":-0.684953,"eighty":-0.267383,"marketCap":36310475},{"date":"2025-04-25","current":-1.814637,"twenty":-1.549421,"median":-0.686912,"eighty":-0.267246,"marketCap":44955826},{"date":"2025-05-02","current":-1.507545,"twenty":-1.56338,"median":-0.6911,"eighty":-0.267246,"marketCap":37347917},{"date":"2025-05-09","current":-1.465669,"twenty":-1.56338,"median":-0.694623,"eighty":-0.267246,"marketCap":36310475},{"date":"2025-05-16","current":-1.422858,"twenty":-1.56338,"median":-0.697871,"eighty":-0.267246,"marketCap":32105376},{"date":"2025-05-23","current":-1.650594,"twenty":-1.570969,"median":-0.702091,"eighty":-0.267246,"marketCap":37244000},{"date":"2025-05-30","current":-1.737281,"twenty":-1.579596,"median":-0.706491,"eighty":-0.267246,"marketCap":39200000},{"date":"2025-06-06","current":-1.684099,"twenty":-1.594388,"median":-0.712833,"eighty":-0.269351,"marketCap":38000000},{"date":"2025-06-13","current":-1.765822,"twenty":-1.621021,"median":-0.71625,"eighty":-0.270599,"marketCap":39844000},{"date":"2025-06-20","current":-1.767417,"twenty":-1.633114,"median":-0.720971,"eighty":-0.270599,"marketCap":39880000},{"date":"2025-06-27","current":-1.80819,"twenty":-1.650083,"median":-0.723179,"eighty":-0.270599,"marketCap":40800000},{"date":"2025-07-03","current":-1.70874,"twenty":-1.675093,"median":-0.724957,"eighty":-0.272371,"marketCap":38556000},{"date":"2025-07-11","current":-1.914554,"twenty":-1.684091,"median":-0.728916,"eighty":-0.274209,"marketCap":43200000},{"date":"2025-07-15","current":-1.772735,"twenty":-1.698144,"median":-0.731459,"eighty":-0.275945,"marketCap":40000000}],"updateTime":1752720763467}}}